2024-11-01 09:00:59, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_011282 7401 bp mRNA linear ROD 02-JUN-2024 DEFINITION Mus musculus Ros1 proto-oncogene (Ros1), mRNA. ACCESSION NM_011282 VERSION NM_011282.2 KEYWORDS RefSeq; RefSeq Select. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. REFERENCE 1 (bases 1 to 7401) AUTHORS Kiyozumi,D. and Ikawa,M. TITLE Adhesion G protein-coupled receptor G2 is dispensable for lumicrine signaling regulating epididymal initial segment differentiation and gene expressiondagger JOURNAL Biol Reprod 109 (4), 474-481 (2023) PUBMED 37531264 REFERENCE 2 (bases 1 to 7401) AUTHORS Kiyozumi,D., Shimada,K., Chalick,M., Emori,C., Kodani,M., Oura,S., Noda,T., Endo,T., Matzuk,M.M., Wreschner,D.H. and Ikawa,M. TITLE A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility JOURNAL Nat Commun 14 (1), 2354 (2023) PUBMED 37095084 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 7401) AUTHORS Jun,H.J., Ali,Z.A. and Charest,A. TITLE Male sterility in ROS1 receptor tyrosine kinase conditionally deleted in epididymal epithelial JOURNAL Biochim Biophys Acta Mol Cell Res 1870 (3), 119413 (2023) PUBMED 36535370 REFERENCE 4 (bases 1 to 7401) AUTHORS Su,J., Miao,X., Archambault,D., Mager,J. and Cui,W. TITLE ZC3H4-a novel Cys-Cys-Cys-His-type zinc finger protein-is essential for early embryogenesis in micedagger JOURNAL Biol Reprod 104 (2), 325-335 (2021) PUBMED 33246328 REFERENCE 5 (bases 1 to 7401) AUTHORS Kiyozumi,D., Noda,T., Yamaguchi,R., Tobita,T., Matsumura,T., Shimada,K., Kodani,M., Kohda,T., Fujihara,Y., Ozawa,M., Yu,Z., Miklossy,G., Bohren,K.M., Horie,M., Okabe,M., Matzuk,M.M. and Ikawa,M. TITLE NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility JOURNAL Science 368 (6495), 1132-1135 (2020) PUBMED 32499443 REFERENCE 6 (bases 1 to 7401) AUTHORS Narayana,L. and Nagarajan,L. TITLE A mouse c-ros genomic clone: identification of a highly conserved 22-amino acid segment in the juxta-membrane domain JOURNAL Gene 118 (2), 297-298 (1992) PUBMED 1324876 REFERENCE 7 (bases 1 to 7401) AUTHORS Tessarollo,L., Nagarajan,L. and Parada,L.F. TITLE c-ros: the vertebrate homolog of the sevenless tyrosine kinase receptor is tightly regulated during organogenesis in mouse embryonic development JOURNAL Development 115 (1), 11-20 (1992) PUBMED 1638975 REFERENCE 8 (bases 1 to 7401) AUTHORS Haefliger,J.A., Bruzzone,R., Jenkins,N.A., Gilbert,D.J., Copeland,N.G. and Paul,D.L. TITLE Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping JOURNAL J Biol Chem 267 (3), 2057-2064 (1992) PUBMED 1370487 REFERENCE 9 (bases 1 to 7401) AUTHORS Siracusa,L.D., Jenkins,N.A. and Copeland,N.G. TITLE Identification and applications of repetitive probes for gene mapping in the mouse JOURNAL Genetics 127 (1), 169-179 (1991) PUBMED 1673105 REFERENCE 10 (bases 1 to 7401) AUTHORS Justice,M.J., Siracusa,L.D., Gilbert,D.J., Heisterkamp,N., Groffen,J., Chada,K., Silan,C.M., Copeland,N.G. and Jenkins,N.A. TITLE A genetic linkage map of mouse chromosome 10: localization of eighteen molecular markers using a single interspecific backcross JOURNAL Genetics 125 (4), 855-866 (1990) PUBMED 1975791 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC155831.7 and AC153950.8. On Sep 14, 2006 this sequence version replaced NM_011282.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U15443.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-414 AC155831.7 66584-66997 415-459 AC155831.7 80005-80049 460-519 AC155831.7 81607-81666 520-546 AC155831.7 82855-82881 547-607 AC155831.7 88927-88987 608-756 AC155831.7 91715-91863 757-895 AC155831.7 93087-93225 896-1097 AC155831.7 95581-95782 1098-1174 AC155831.7 96412-96488 1175-1297 AC155831.7 97821-97943 1298-1482 AC155831.7 98938-99122 1483-1580 AC155831.7 99922-100019 1581-2077 AC155831.7 106550-107046 2078-2290 AC155831.7 115868-116080 2291-2401 AC155831.7 116953-117063 2402-2580 AC155831.7 118403-118581 2581-2772 AC155831.7 119497-119688 2773-2873 AC155831.7 130842-130942 2874-3088 AC155831.7 132051-132265 3089-3249 AC155831.7 132729-132889 3250-3394 AC155831.7 133267-133411 3395-3657 AC155831.7 135847-136109 3658-3721 AC155831.7 137707-137770 3722-3924 AC155831.7 138409-138611 3925-4130 AC155831.7 140827-141032 4131-4414 AC155831.7 143425-143708 4415-4591 AC155831.7 145766-145942 4592-4791 AC155831.7 159920-160119 4792-4936 AC155831.7 161687-161831 4937-5169 AC155831.7 162926-163158 5170-5346 AC155831.7 165630-165806 5347-5515 AC155831.7 170714-170882 5516-5633 AC155831.7 173830-173947 5634-5824 AC155831.7 176474-176664 5825-5908 AC153950.8 1623-1706 5909-6044 AC153950.8 5681-5816 6045-6207 AC153950.8 7690-7852 6208-6272 AC153950.8 10533-10597 6273-6402 AC153950.8 11482-11611 6403-6500 AC153950.8 16563-16660 6501-6701 AC153950.8 17252-17452 6702-6836 AC153950.8 18857-18991 6837-7000 AC153950.8 32628-32791 7001-7401 AC153950.8 37339-37739 FEATURES Location/Qualifiers source 1..7401 /organism="Mus musculus" /mol_type="mRNA" /db_xref="taxon:10090" /chromosome="10" /map="10 26.18 cM" gene 1..7401 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Ros1 proto-oncogene" /db_xref="GeneID:19886" /db_xref="MGI:MGI:97999" exon 1..414 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" misc_feature 250..252 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="upstream in-frame stop codon" CDS 289..7311 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /EC_number="2.7.10.1" /note="proto-oncogene tyrosine-protein kinase ROS; c-ros-1; proto-oncogene c-Ros-1; c-Ros receptor tyrosine kinase; receptor tyrosine kinase c-ros oncogene 1" /codon_start=1 /product="proto-oncogene tyrosine-protein kinase ROS precursor" /protein_id="NP_035412.2" /db_xref="CCDS:CCDS23838.1" /db_xref="GeneID:19886" /db_xref="MGI:MGI:97999" /translation="
MKNICWLTLKLVKFVVLGCIIWISVAQSTVLSSCLTSCVTNLGRQLDSGTRYNLSEACIHGCQFWNSVDQETCALKCNDTYATICERESCEVGCSNAEGSYEEEVLESTELPTAPFASSIGSHGVTLRWNPANISGVKYIIQWKYAQLPGSWTFTETVSKLSYTVEPLHPFTEYIFRVVWIFTAQLHLYSPPSPSYRTHPYGVPETAPLILNMESWSPDTVEVSWAPPHFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEGPEAESTVTTPSPSVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLWSDAIHHNITGISVYAQQQVVYFSEGTVIWMKGAANMSDVSDLRIFYQGSGLVSSISIDWLYQRMYFIMDKLVYVCELKNCSNLEEITPFSLIAPQKVVVDSYNGYLFYLLRDGIYRVNLPLPSGRDTKAVRIVESGTLKDFAVKPQSKRIIYFNDTMQLFMSTFLDGSAFHRVLPWVPLVTVKSFACENNDFLITDGKAIFQQDSLSFNEFIVGCDLSHIEEFGFGNLVIFGSSVQSYPLPGHPQEVSVLFGSREALIQWTPPALAIGASPSAWQNWTYEVKVYSQDILEITQVFSNISGTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVGTTLVPATEPPFIMAVKEDGLWSKPLCSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTKGNVYVRPLNGMDISENYHIPSIVGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIVTHVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKKVIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWSGGDATITEFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSEPAKFNQFTIIQTSLKPLPGNFSSTPKVIPDPVQESSFRIEGHTSSFQILWNEPPAVDWGIVFYSVEFSTHSKFLIIEQQSLPIFTVEGLEPYTLFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSSGRYTKKNEVVVEFRWNKPKHENGVLTKFEIFYHISKQSGTNRSTEDWMSASVIPPVMSFQLEAVSPEYTVAFQVRVFTSKGPGPFSDIVMSKTSEIKPCPYLISLLGNKIVFLDMDQNQVLWTFSLEGDVSTVGYTTDDEMGYFAQGDTLFLLNLRNHSSSKLFQDALVSDIRVIAVDWIARHLYFALKASQNGTQIFNVDLEHKVKSPREVKTCKAHTTIISFSIYPLLSRLYWTEVSDLGHQMFYCNISNHTSQHVLQPKASNQHGRSQCSCNVTESELSGAMTVDTSDPDRPWIYFTKRQEIWAMDLEGCQCWKVIMVPTIPGKRIISLTVDGEFIYWIMKTKDDAQIYQAKKGSGAILSQVKASRSKHILAYSSALQPFPDKAYLSLASDMVEATILYATNTSLTLKLPPVKTNLTWHGITHPTSTYLIYYMEANRANSSDRRHKMLESQENVARIEGLQPFSMYMIQIAVKNYYSEPLEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTESHKPNGPKESVRYQLVMSYLAPIPETPLRQGEFPSAKLSLLITKLSGGQLYVMKVLACHPEEMWCTESHPVSVNMFDTPEKPSALVPENTSLQLDWKARSNVNLTGFWFELQKWKYNEFYHVKASCSQGPVYVCNITDLQPYTSYNIRVVVVYTTGENSSSIPESFKTKAGVPSKPGIPKLLEGSKNSIQWEKAEDNGSRLMYYTLEVRKGISNDSQNQSSRWKVVFNGSCSSICTWRSKNLKGTFQFRAVAANEIGLGEYSEISEDITLVEDGVWITETSFILTIIVGIFLVATVPLTFVWHRSLKSHKASKEGLSVLNDNDKELAELRGLAAGVGLANACYAVHTVPTQEEIENLPAFPREKLSLRLLLGSGAFGEVYEGTAIDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTFHGPSLTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYKNDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQLFRNVFLNNVSHCGEAAPTGGVINKGFEGEDDEMVTLNSDDTMPVALMETKNQEGLNYMVLATKCSQGEGSYEGPLGPKELGSCDLKKDKKQPQADKDFCQEPQVAYGSPGLSEGLNYACLAHSEHGDVSE"
sig_peptide 289..372 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="COORDINATES: ab initio prediction:SignalP:6.0" mat_peptide 373..7308 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /product="Proto-oncogene tyrosine-protein kinase ROS. /id=PRO_0000278115" /note="propagated from UniProtKB/Swiss-Prot (Q78DX7.1)" misc_feature 445..447 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q78DX7.1); glycosylation site" misc_feature <586..>1176 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain [General function prediction only]; Region: FN3; COG3401" /db_xref="CDD:442628" misc_feature 1288..1290 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q78DX7.1); glycosylation site" misc_feature 1372..1374 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q78DX7.1); glycosylation site" misc_feature 1990..2280 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature order(1990..1992,2197..2199,2242..2244) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature order(2245..2250,2254..2259) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 3091..3093 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q78DX7.1); glycosylation site" misc_feature 3319..3321 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q78DX7.1); glycosylation site" misc_feature 3397..3717 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature order(3397..3399,3634..3636,3679..3681) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Interdomain contacts [active]" /db_xref="CDD:238020" misc_feature order(3682..3687,3691..3696) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 4015..4017 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q78DX7.1); glycosylation site" misc_feature <4789..>5544 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain [General function prediction only]; Region: FN3; COG3401" /db_xref="CDD:442628" misc_feature 5236..5511 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature 5314..5316 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q78DX7.1); glycosylation site" misc_feature order(5476..5481,5485..5490) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 5524..5805 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063" /db_xref="CDD:238020" misc_feature order(5779..5784,5788..5793) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Cytokine receptor motif [active]" /db_xref="CDD:238020" misc_feature 5851..5913 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="propagated from UniProtKB/Swiss-Prot (Q78DX7.1); transmembrane region" misc_feature 6130..6915 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Catalytic domain of the Protein Tyrosine Kinase, C-ros; Region: PTKc_c-ros; cd05044" /db_xref="CDD:270640" misc_feature order(6130..6132,6142..6144,6199..6201,6205..6207, 6343..6354,6361..6366,6502..6504,6514..6519,6523..6525, 6571..6573,6625..6639,6664..6666,6766..6768) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="active site" /db_xref="CDD:270640" misc_feature order(6130..6132,6142..6144,6199..6201,6205..6207, 6343..6354,6361..6366,6514..6519,6523..6525,6571..6573) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="ATP binding site [chemical binding]; other site" /db_xref="CDD:270640" misc_feature order(6502..6504,6514..6516,6625..6639,6664..6666, 6766..6768) /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="polypeptide substrate binding site [polypeptide binding]; other site" /db_xref="CDD:270640" misc_feature 6568..6645 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="activation loop (A-loop); other site" /db_xref="CDD:270640" misc_feature 7087..7089 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Phosphotyrosine, by autocatalysis. /evidence=ECO:0000269|PubMed:11266449; propagated from UniProtKB/Swiss-Prot (Q78DX7.1); phosphorylation site" misc_feature 7267..7269 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="Phosphotyrosine, by autocatalysis. /evidence=ECO:0000250|UniProtKB:P08922; propagated from UniProtKB/Swiss-Prot (Q78DX7.1); phosphorylation site" exon 415..459 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 460..519 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 520..546 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 547..607 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 608..756 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 757..895 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 896..1097 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 1098..1174 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 1175..1297 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 1298..1482 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 1483..1580 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 1581..2077 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 2078..2290 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 2291..2401 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 2402..2580 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 2581..2772 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 2773..2873 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 2874..3088 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 3089..3249 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 3250..3394 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 3395..3657 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 3658..3721 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 3722..3924 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 3925..4130 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 4131..4414 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 4415..4591 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 4592..4791 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 4792..4936 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 4937..5169 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 5170..5346 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 5347..5515 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 5516..5633 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 5634..5824 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 5825..5908 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 5909..6044 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 6045..6207 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 6208..6272 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 6273..6402 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 6403..6500 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 6501..6701 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 6702..6836 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 6837..7000 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" exon 7001..7401 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /inference="alignment:Splign:2.1.0" regulatory 7373..7378 /regulatory_class="polyA_signal_sequence" /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="hexamer: AATAAA" polyA_site 7395 /gene="Ros1" /gene_synonym="c-ros; Ros-1" /note="major polyA site" ORIGIN
cctggatctaacttttagccagggaatgtcttttgttatgggagcaaaaggaagctaaactataaaatagccttgctgcgatgttctgggctatctaagatccaaaggtctaaactaatccaaaggcctcaatattctttttaaagagagaatgatattctaacattgcgaaagaaaacagaaaacctacttgtcacacttgcaactgaagtatgaagcctaaagagttcttaaagcaaggtggagctatgaggaccccagctgtgtaggaagccagccctcctgaggatgaagaacatctgctggctcaccctgaaacttgtgaagtttgtggtccttgggtgcatcatatggatttctgtggcacagagtacagttctgagcagctgcctaacgtcctgtgtaactaacctgggcaggcagcttgacagtggcacacggtacaatctgagtgaggcgtgcatccatggatgtcagttttggaactctgtagatcaggaaacgtgtgctttaaagtgtaatgacacctacgccaccatttgtgagagggagtcctgtgaggtcggctgcagcaatgcggagggtagctacgaagaggaagtgctggaaagcacagaacttcctacagcaccctttgcatcttccattggaagtcatggtgtgacattacgctggaaccctgccaacatctctggagtcaaatacataattcaatggaaatatgcccaacttccaggaagctggactttcacggagaccgtgtccaagctctcatacacggtggaacccctgcatccattcacagaatatatttttcgagtggtttggatcttcacagcccaactgcatctttattccccaccaagtcccagttacaggactcatccttatggagttccagaaactgcacctctcatcctgaacatggaaagctggagccctgatactgtggaggtcagctgggctccacctcatttcccaggtggacctattttgggttataatttaaggctcatcagtaaaaatcaaaaattagattcagggacacagagaaccagtttccagttttattctactctaccaaacaccacctacaggttttctatcgcagcagtcaatgaagttggtgaggggccagaagcagaatctacagttaccactccatccccatcagttcaagaagaagaacaatggctctttttatccagaaaaacttctctaagaaagaggtctttgaagtacttagtagatgaagcacattgcctttggtcagatgctatacaccataatattacaggaatatcagtctatgctcagcagcaagtggtttatttttcagaaggaactgtcatctggatgaagggggctgccaacatgtctgatgtgtctgacctgagaattttttaccaaggctcaggtctagtgtcttctatctccatagactggctgtaccaaaggatgtatttcatcatggataaactggtatatgtctgtgaattaaagaattgctcaaatttagaggaaatcactcccttctctcttattgcacctcagaaagttgtggttgactcctacaatgggtacctcttttatctcctgagagacggcatctacagagtcaatctccctttgccatctggcagggacaccaaagctgtgcgtattgtggagagtggcacattaaaggactttgcagtaaagccccaatccaagcgaatcatttacttcaatgacaccatgcaactcttcatgtcaacgtttctggatggctctgccttccaccgggtcctgccttgggtcccccttgtgactgtgaagagctttgcttgtgaaaacaatgacttcctcatcacagatggcaaggccatttttcagcaggactccctgtctttcaatgaattcatcgtgggatgtgacctgagtcacatagaagagtttgggtttggtaacttggtcatctttggctcctctgtccagtcataccctctgccaggacatccacaggaggtctcagtgctgtttggttctcgagaggcccttattcagtggacgcctcctgctctcgccataggagccagtccttccgcctggcagaactggacttatgaagtcaaagtttattcccaggacatccttgaaatcactcaagttttctcgaacataagcgggaccatgcttaatgtacccgaactgcagagttctacaaagtacactgtctctgtgagagcaagttctcctaaaggcccaggcccctggtcagcaccatcagtgggtaccaccttggtaccagctactgaaccaccattcatcatggctgtgaaagaagatgggctctggagcaaaccactctgtagttttggtccaggagaattcctgtcctctgatgtaggaaacgtgtcagatatggattggtacaacaacagcctctactacagtgacacaaaaggcaacgtttatgtgcggcctctgaatgggatggatatctcagagaattatcacatacccagcattgtaggagctggggctttggcctttgaatggctgggtcactttctctactgggctgggaagacatatgtgatccaaaggcagtctgtgttgacgggacacacggacattgtgactcatgtgaagctgttggtgaatgacatggctgtggattcagttggtggctatctctattggacaacactctactcagttgaaagcaccagactcaatggagaaagttctcttgtactacaggctcagccctggctctctggaaaaaaggttattgctctaacactagacctcagtgatgggctcctgtattggctggtgcaggacaatcagtgtattcatctgtacacagctgttcttcgaggatggagtggtggggatgctaccatcacagagtttgcagcctggagtacttctgaaatctcccagaatgcactgatgtactacagtggtagactcttctggatcaatggatttaggatcattacagcacaggaaataggtcagagaaccagtgtgtctgtttcggagccagcgaaattcaatcagttcacaattatacagacatctctcaagcctctgccaggaaacttttcctctactcccaaggttatcccagatcctgttcaggagtcttcatttcgaattgaaggacacacttcaagtttccaaatcctgtggaatgagccccctgcggtggactggggcatcgttttctacagtgtggaatttagcactcattccaagttcctgattattgaacaacagtctttacctatttttactgtggaaggactggagccctataccttatttaatctttctgtcactccttatacctactggggaaagggccaaaaaacatctctatcatttcgtgcacctgaatcagttccatcagcaccagaaaaccccagaatatttatattgtcaagcggaagatacaccaagaagaatgaagttgtggtagagttcaggtggaataaacctaagcatgaaaatggagtgctaaccaaatttgaaatcttctatcacatatctaaacaaagtggcacaaatagatcaactgaagactggatgtctgccagtgttatacccccagtgatgtcttttcaacttgaggctgtgagtcctgagtatactgttgccttccaggttagagtcttcacatccaaagggccagggccattttctgatatagtgatgtctaaaacatcagaaatcaagccatgtccgtatctcatatctcttctcggcaataagatcgtgtttctagacatggatcaaaatcaagttttgtggacattttccctggagggagacgtcagcacagtggggtacacaacagacgatgaaatggggtatttcgctcaaggagacacgctcttccttctgaatttgcgtaatcattccagttccaagcttttccaggatgcactggtttctgacattagagttattgctgttgattggattgcaaggcacctctactttgctctgaaagcatcacaaaacggaacacagatattcaatgttgaccttgaacacaaggtgaaatcccccagggaggtgaagacttgcaaagcacatacaacaataatttctttctctatatatcccctcttgagtcgcttgtattggacagaagtttcagatctgggccatcagatgttctactgcaatattagcaatcacacctcgcaacatgttctacaacccaaggcttcaaaccaacatggaaggagtcaatgttcttgtaatgtgacagaatctgagttaagtggggcaatgactgtggatacctctgacccagacagaccatggatatactttaccaaaaggcaagagatctgggccatggatctggaaggatgtcagtgttggaaagtcatcatggtacctactatccctggaaaaagaatcattagcttaacagtggatggggagtttatatattggatcatgaaaacaaaggatgatgcccaaatttatcaagcaaagaagggaagcggggccatcctttcccaagtgaaggcctccaggagtaagcatatcttggcttacagttctgctctgcagccttttccagataaagcatatctgtctctagcttcagatatggtagaagcaactatattatatgccaccaacaccagcctcacactcaaattacctccagtcaagacaaacctcacgtggcatggtattacccaccccacgtcaacatacctgatttactatatggaagctaatagggcaaacagctctgacaggagacacaaaatgctggaatcacaggagaatgtagcccggattgaaggtctgcagccattttcaatgtacatgattcagatagctgtgaagaactattattcagagcctttagaacatttacctcttggaaaagagattcaaggacaaactaaaagtggagtgcctggggcagtttgtcatatcaacgcaactgtgttgtcggacaccagtctccatgtattctggacagaatcccataagccaaacggaccaaaagagtcagtccgctatcagctggttatgtcatacctggctcccattcctgagactcctctaagacagggtgaatttccaagtgccaagctttctctgctcatcactaaactatctggtggacagctctatgtgatgaaggttctggcgtgccaccctgaggaaatgtggtgtactgagagtcatcctgtcagtgtcaacatgtttgacacaccagagaaaccctctgccttggttccagagaacactagtctgcagttagattggaaggctcgatcaaacgttaacctcaccggattttggtttgaactccagaagtggaaatataatgagttttaccatgtcaaagcttcatgcagccaaggtccagtttatgtctgtaacatcacagatctacaaccttacacctcctataacattcgagtggtggtggtctatacgacaggagaaaatagctcctccattccagagagtttcaagacaaaagccggagtcccaagcaaaccaggtattcctaaattactagaagggagtaaaaattccatccagtgggaaaaagctgaagataatgggagcagattgatgtactacacccttgaggtcagaaaaggcatttcaaatgactcacagaaccagagttcaaggtggaaggtggtgtttaatgggtcctgcagtagcatttgcacatggagatcaaaaaacctaaaaggaacatttcagttcagagcagttgctgcaaatgaaattggacttggagaatatagtgaaatcagtgaagacattacattagtggaagatggtgtttggataacagaaacaagttttatacttactatcatagttgggatatttctggttgctacagtcccactgacctttgtctggcatagaagcttgaaaagtcacaaagcttccaaggaaggcctctcggttctcaacgacaacgacaaagagttggctgagcttcgaggtctggcggctggagtgggactggccaatgcctgctacgcagtacatactgttccaacccaagaagagattgaaaatcttcctgccttccctcgggagaagctgagcctgcgtcttttgttgggaagtggagcttttggagaagtgtatgaaggcacagctatagacatcctaggcgtgggaagtggagaaatcaaagtggcagtgaagaccttgaagaaaggttcaacagaccaggagaagattgagttcctgaaggaggcgcacctgatgagcaagtttaatcaccccaacattctgaagcagctgggagtctgtctgttaggcgaaccccagtacattattctggaactgatggaagggggagaccttctaagctatctgcgcaaagctcgggggacaacgtttcatggtccttcactcaccttgcttgaccttgtagagctgtgtgtagatatttcaaaaggctgcgtctacttggagcagatgcacttcattcacagggatctggcagctcggaattgccttgtatcagtgaaagactacaccagtcctcgggtagtcaagattggtgactttggattggcaagagaaatctataaaaatgattattatagaaagagaggggaaggcctgcttcctgttcggtggatggctcctgaaaacttgatggacggaatcttcacttctcagtctgatgtatggtcctttggaattttggtgtgggagattttaactctcggtcatcaaccttatccagcgcattccaaccttgatgttttaaactatgtgcaagcaggagggagactggagccaccaagaaattgtcctgatgatctgtggaatttaatgtcccaatgctgggctcaagaacctgaccaaagacccactttccataacattcaaaaccagcttcagttattcagaaatgttttcttaaacaatgtttctcattgtggagaagcagctcccaccggtggagtcatcaacaaaggctttgaaggtgaagatgatgaaatggtcactttgaactcagatgacacgatgccagttgccttgatggaaaccaagaaccaagaaggattaaattatatggtgcttgccacaaaatgtagccaaggtgaaggaagttatgagggtcctctaggccctaaggaacttgggtcatgtgatctgaagaaagacaagaagcaaccacaggcagacaaagatttctgccaggaaccacaggtggcttatggctctcctggcctgtctgaaggcctgaattatgcctgtcttgctcacagtgaacatggagatgtgtctgaataatagtgtctcgtaggaaatacagcactgagatcaacatcgtgttaagttacttgcagaaaagaataaagttgtggtggcagttgactctga
//
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@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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