LOCUS       NM_001411493            1491 bp    mRNA    linear   ROD 08-AUG-2023
DEFINITION  Mus musculus alcohol dehydrogenase 6B (class V) (Adh6b), transcript
            variant 4, mRNA.
ACCESSION   NM_001411493
VERSION     NM_001411493.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Szalai G, Veres M, Duester G, Lawther R, Lockhart M and Felder MR.
  TITLE     Tissue expression pattern of class II and class V genes found in
            the Adh complex on mouse chromosome 3
  JOURNAL   Biochem Genet 46 (11-12), 685-695 (2008)
   PUBMED   18802746
  REMARK    GeneRIF: Adh6b gene expression patterns.
REFERENCE   2  (bases 1 to 1491)
  AUTHORS   Gonzalez-Duarte R and Albalat R.
  TITLE     Merging protein, gene and genomic data: the evolution of the
            MDR-ADH family
  JOURNAL   Heredity (Edinb) 95 (3), 184-197 (2005)
   PUBMED   16121213
  REMARK    Review article
REFERENCE   3  (bases 1 to 1491)
  AUTHORS   Szalai G, Duester G, Friedman R, Jia H, Lin S, Roe BA and Felder
            MR.
  TITLE     Organization of six functional mouse alcohol dehydrogenase genes on
            two overlapping bacterial artificial chromosomes
  JOURNAL   Eur J Biochem 269 (1), 224-232 (2002)
   PUBMED   11784316
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC079845.31.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189673.178562.1,
                                           SRR5189679.90081.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849375,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AC079845.31        58011-58036
            27-120              AC079845.31        58200-58293
            121-219             AC079845.31        58836-58934
            220-321             AC079845.31        60106-60207
            322-460             AC079845.31        65669-65807
            461-548             AC079845.31        68205-68292
            549-768             AC079845.31        68417-68636
            769-1029            AC079845.31        68818-69078
            1030-1165           AC079845.31        70039-70174
            1166-1304           AC079845.31        73684-73822
            1305-1491           AC079845.31        74711-74897
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 64.21 cM"
     gene            1..1491
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="alcohol dehydrogenase 6B (class V)"
                     /db_xref="GeneID:100417514"
                     /db_xref="MGI:MGI:2446626"
     exon            1..26
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            27..120
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            121..219
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    130..132
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="upstream in-frame stop codon"
     CDS             181..1335
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /EC_number="1.1.1.1"
                     /codon_start=1
                     /product="alcohol dehydrogenase 6B (class V)"
                     /protein_id="NP_001398422.1"
                     /db_xref="GeneID:100417514"
                     /db_xref="MGI:MGI:2446626"
                     /translation="

MEQASLATKTSSNVIRCRAAVAWTTNAPLSIEEVEVDPPKAGEVRVKIIASGICGTDNHTLEGKMKTPFPVILGHEGAGVVESVGPGVTTVKPGDKVLMFPLPECRECFYCLYPKGNFCEKENILSPTGLMLDGTSRFTCRGKKIYNIMGTSTFTEYTVVHEIAVAKIEAAAPMDTVCIMSCAVPTGFGAVFNTAQVTPGSSCVVFGLGGIGSAIVMACKASGACRIIGVDINEEKFPRARALGVTDCLNPNKLKKPVQEVVKEMTGVGVDFAFEAIGLIETMVAALKSCNRSYGVCVIMGVAPTGSQLSFDPLVLLPGRTLKSSVLGGYKTRDDIPKLVTDYVQKKINIDPLITHRLPFPKINEGFRLLQEGKCIRCVLSMRP"

     misc_feature    208..1326
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="Medium chain reductase/dehydrogenase
                     (MDR)/zinc-dependent alcohol dehydrogenase-like family;
                     Region: MDR; cl16912"
                     /db_xref="CDD:450120"
     misc_feature    order(340..348,355..357,724..726,736..738,799..816,
                     871..876,886..888,931..933,1006..1011,1078..1083,
                     1153..1161)
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:176178"
     exon            220..321
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            322..460
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            461..548
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            549..768
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            769..1029
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1165
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1304
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1491
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agtccgccctgcatttactctctgaggtgttaaatgtgcagagcttgatgtgtttttctttcaaggtgttaaatgtgcagagcttggtaggacactcccgtatacgtggcacttcggcagtccagcaggtaaccgcttgagacagaagagccctccagtctaaaccttccagaagcaaagatggaacaagccagcctcgccacaaaaacatccagcaatgtcatcagatgccgggcagctgttgcctggaccactaatgccccgctgtccattgaggaggttgaagttgatccaccaaaggctggtgaggttcgagttaagattatagcctctgggatctgtggcactgataatcataccttagaagggaaaatgaaaacgccatttcctgtcatcctgggccacgagggagctggagttgtggagagtgttggaccaggtgtaaccactgtaaagccaggagataaagtcttaatgttccctcttccggaatgtcgagaatgcttctactgcctctaccctaagggcaacttctgtgagaaagaaaatattctctctccaactggattaatgttggatggaaccagcagatttacctgcagagggaagaaaatctataatataatggggaccagcacgttcacggaatatactgtggtgcatgagattgcagtggcgaagatcgaggctgctgcccctatggatacagtctgcatcatgagctgcgcggtgccgacaggctttggagctgtgtttaacacagctcaggtcacccctggctcttcctgtgtggtgtttggactcggaggaattggctctgccatcgtcatggcctgcaaagcctctggagcatgtagaatcatcggggttgacatcaatgaggagaaatttcctcgggcaagagccttgggggtcaccgactgtctcaaccctaacaagctgaagaagcctgtgcaggaggtggtgaaggaaatgacaggggttggtgttgactttgcctttgaggccatcggactcattgaaaccatggttgcggctttgaagtcatgcaataggagctacggagtgtgtgtgattatgggagtagctccgaccggttcccagctctcttttgacccattggtacttctccctggaagaaccctaaaatcttctgttttgggagggtataaaaccagagatgacatccctaaactagtaactgactacgttcaaaagaaaattaatatagatcctcttataacccatagactgcctttcccaaaaatcaatgaaggattcagattgttgcaagagggaaaatgcatccgttgtgtcctctctatgagaccctgatggtgaccggcacacgggcatctcagcagtgctcttctatgcttctttacctccttggagattaaactgcaaactatggagatcagaacaggaaacacacacacacaattttaacgaattaaactgttaaagaaaataaactatctcaaaactctt

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