ver.2
Home
|
Help
|
Advanced search
Previous release (v1)
2024-05-06 12:16:31, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NM_001360093 4376 bp mRNA linear ROD 31-OCT-2023
DEFINITION Mus musculus exocyst complex component 2 (Exoc2), transcript
variant 2, mRNA.
ACCESSION NM_001360093 XM_006516726
VERSION NM_001360093.1
KEYWORDS RefSeq.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 4376)
AUTHORS Xu J, Liu H, Lan Y and Jiang R.
TITLE Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene
Expression in Palate Development
JOURNAL Front Cell Dev Biol 9, 665109 (2021)
PUBMED 33898467
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 4376)
AUTHORS Xu J, Liu H, Lan Y, Park JS and Jiang R.
TITLE Genome-wide Identification of Foxf2 Target Genes in Palate
Development
JOURNAL J Dent Res 99 (4), 463-471 (2020)
PUBMED 32040930
REFERENCE 3 (bases 1 to 4376)
AUTHORS Seixas C, Choi SY, Polgar N, Umberger NL, East MP, Zuo X, Moreiras
H, Ghossoub R, Benmerah A, Kahn RA, Fogelgren B, Caspary T,
Lipschutz JH and Barral DC.
TITLE Arl13b and the exocyst interact synergistically in ciliogenesis
JOURNAL Mol Biol Cell 27 (2), 308-320 (2016)
PUBMED 26582389
REFERENCE 4 (bases 1 to 4376)
AUTHORS Xie L, Zhu D, Kang Y, Liang T, He Y and Gaisano HY.
TITLE Exocyst sec5 regulates exocytosis of newcomer insulin granules
underlying biphasic insulin secretion
JOURNAL PLoS One 8 (7), e67561 (2013)
PUBMED 23844030
REMARK GeneRIF: Exocyst sec5 regulates exocytosis of newcomer insulin
granules underlying biphasic insulin secretion.
Publication Status: Online-Only
REFERENCE 5 (bases 1 to 4376)
AUTHORS Heider MR and Munson M.
TITLE Exorcising the exocyst complex
JOURNAL Traffic 13 (7), 898-907 (2012)
PUBMED 22420621
REMARK Review article
REFERENCE 6 (bases 1 to 4376)
AUTHORS Nichols CD and Casanova JE.
TITLE Salmonella-directed recruitment of new membrane to invasion foci
via the host exocyst complex
JOURNAL Curr Biol 20 (14), 1316-1320 (2010)
PUBMED 20579884
REFERENCE 7 (bases 1 to 4376)
AUTHORS Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND and Robson P.
TITLE Resolution of cell fate decisions revealed by single-cell gene
expression analysis from zygote to blastocyst
JOURNAL Dev Cell 18 (4), 675-685 (2010)
PUBMED 20412781
REFERENCE 8 (bases 1 to 4376)
AUTHORS Saito T, Shibasaki T and Seino S.
TITLE Involvement of Exoc3l, a protein structurally related to the
exocyst subunit Sec6, in insulin secretion
JOURNAL Biomed Res 29 (2), 85-91 (2008)
PUBMED 18480549
REFERENCE 9 (bases 1 to 4376)
AUTHORS Mott HR, Nietlispach D, Hopkins LJ, Mirey G, Camonis JH and Owen D.
TITLE Structure of the GTPase-binding domain of Sec5 and elucidation of
its Ral binding site
JOURNAL J Biol Chem 278 (19), 17053-17059 (2003)
PUBMED 12624092
REMARK GeneRIF: the structure of the Ral-binding domain of Sec5
REFERENCE 10 (bases 1 to 4376)
AUTHORS Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng
EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC,
Babbitt PC and Ferrin TE.
TITLE BayGenomics: a resource of insertional mutations in mouse embryonic
stem cells
JOURNAL Nucleic Acids Res 31 (1), 278-281 (2003)
PUBMED 12520002
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AL606764.19 and AL645745.7.
On Jan 26, 2018 this sequence version replaced XM_006516726.2.
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
##Evidence-Data-START##
Transcript exon combination :: AK016532.1 [ECO:0000332]
RNAseq introns :: mixed sample support SAMN00849374,
SAMN00849375 [ECO:0006172]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-119 AL606764.19 84105-84223 c
120-178 AL606764.19 80290-80348 c
179-339 AL606764.19 74535-74695 c
340-516 AL606764.19 72041-72217 c
517-643 AL606764.19 69420-69546 c
644-757 AL606764.19 61233-61346 c
758-882 AL606764.19 59648-59772 c
883-963 AL606764.19 45095-45175 c
964-1109 AL606764.19 40657-40802 c
1110-1191 AL606764.19 40428-40509 c
1192-1294 AL606764.19 39578-39680 c
1295-1413 AL606764.19 34710-34828 c
1414-1539 AL606764.19 20114-20239 c
1540-1664 AL606764.19 16174-16298 c
1665-1730 AL606764.19 11473-11538 c
1731-1888 AL606764.19 11168-11325 c
1889-2010 AL606764.19 10656-10777 c
2011-2072 AL606764.19 9184-9245 c
2073-2153 AL606764.19 6214-6294 c
2154-2213 AL606764.19 5767-5826 c
2214-2275 AL606764.19 5044-5105 c
2276-2342 AL645745.7 137839-137905 c
2343-2459 AL645745.7 134698-134814 c
2460-2601 AL645745.7 126521-126662 c
2602-2657 AL645745.7 95906-95961 c
2658-2780 AL645745.7 92499-92621 c
2781-2842 AL645745.7 90445-90506 c
2843-2902 AL645745.7 87865-87924 c
2903-4376 AL645745.7 83785-85258 c
FEATURES Location/Qualifiers
source 1..4376
/organism="Mus musculus"
/mol_type="mRNA"
/strain="C57BL/6"
/db_xref="taxon:10090"
/chromosome="13"
/map="13"
gene 1..4376
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="exocyst complex component 2"
/db_xref="GeneID:66482"
/db_xref="MGI:MGI:1913732"
exon 1..119
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 120..178
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 179..339
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
misc_feature 189..191
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="upstream in-frame stop codon"
CDS 222..2996
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="isoform 1 is encoded by transcript variant 2;
exocyst complex component Sec5; SEC5-like 1; SEC5 homolog"
/codon_start=1
/product="exocyst complex component 2 isoform 1"
/protein_id="NP_001347022.1"
/db_xref="CCDS:CCDS26420.1"
/db_xref="GeneID:66482"
/db_xref="MGI:MGI:1913732"
/translation="
MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKCKLPQKNLEVLFHGMSADFTSENFSAAWYLIENHSTTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGHPGPHSPMLDLDNDVRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQSERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPLSLREGDGRQYGGWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIRCIMVTLQHTAEEIKRLAEKEDWVVDNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKTQEEVCQLCINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDTVAIYLTSESRSSFKQALEALPQLASGADKKSLEELLNKFKSSMHLQLTCFQAASPAVMKT"
misc_feature 243..494
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="IPT/TIG domain; Region: TIG; pfam01833"
/db_xref="CDD:426462"
misc_feature 615..2963
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="Exocyst complex component Sec5; Region: Sec5;
pfam15469"
/db_xref="CDD:434738"
misc_feature 1512..1514
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q96KP1; propagated from
UniProtKB/Swiss-Prot (Q9D4H1.1); phosphorylation site"
misc_feature 1515..1517
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q96KP1; propagated from
UniProtKB/Swiss-Prot (Q9D4H1.1); phosphorylation site"
misc_feature 1524..1526
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q96KP1; propagated from
UniProtKB/Swiss-Prot (Q9D4H1.1); phosphorylation site"
misc_feature 1539..1541
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="Phosphothreonine.
/evidence=ECO:0000250|UniProtKB:Q96KP1; propagated from
UniProtKB/Swiss-Prot (Q9D4H1.1); phosphorylation site"
misc_feature 1581..1583
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/note="N6-acetyllysine.
/evidence=ECO:0000250|UniProtKB:Q96KP1; propagated from
UniProtKB/Swiss-Prot (Q9D4H1.1); acetylation site"
exon 340..516
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 517..643
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 644..757
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 758..882
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 883..963
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 964..1109
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 1110..1191
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 1192..1294
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 1295..1413
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 1414..1539
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 1540..1664
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 1665..1730
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 1731..1888
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 1889..2010
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2011..2072
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2073..2153
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2154..2213
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2214..2275
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2276..2342
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2343..2459
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2460..2601
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2602..2657
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2658..2780
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2781..2842
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2843..2902
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
exon 2903..4376
/gene="Exoc2"
/gene_synonym="2410030I24Rik; Gm29675; Sec5; Sec5l1"
/inference="alignment:Splign:2.1.0"
ORIGIN
ttatggcaggtgtgcattgaggagcaacaccagttctctcatgttccagggagcaggaagaaatggaacatgtttgaaagcatggcccgtggcctaagggctaggcccaccttctgaagattccgagaggcaaacaagggtcttctgaaggtcctcggtaggagtctttacgttactggttgcttctataactggatcacgagtttgctgcacaaagtaccatgtctcgatcccggcagcccccacttgtaacaggcatctctccaaatgaaggaataccttggaccaaagtcacaattagaggggagaacctgggtactggtcccactgacctcataggcttgacaatttgtggacataattgcctcctcacggcagaatggatgtctgcgagtaaaattgtctgtcgagtgggacaagccaaaaatgacaaaggagacattattgtcacaactaagtcagggggtaaaggaacctcaactgtctcttttaagctactcaagcctgaaaaaataggcattttagatcagtctgcagtgtgggtggatgaaatgaattattatgatatgcggactgacaggaacaaagggattcctcccttgtctctccgtcctgcgaatcctcttggcattgaaattgagaaatgtaaacttcctcagaagaacttagaagtgttattccatggcatgagtgctgattttacaagtgagaatttttcagcagcctggtatctcatagagaatcactccaccaccagttttgagcagctcaagatggcggtcaccaacctcaaaaggcaggccaacaagaagagtgagggtagtctggcatatgtgaagggcggcctcagtaccttctttgaagctcaagatgctctctcagctatccatcaaaaactagaagcagatggaactgaaaaagtagaaggatccatgacacagaaattggagaatgtcctcaatagagcaagtaacaccgctgacacattgttccaagaagtattaggtcggaaagacaaggcagattccactaggaacgccctcaacgtacttcagcgatttaaatttctcttcaaccttcctctcaatattaaacggaatattcaaaagggggattatgatgtagttattaatgattatgaaaaagccaaatcgctctttgggaaaacggaggtgcaagttttcaagaaatattatgctgaagtagaagcaggaattgaagatctaagagagttacttctaaagaaattgctcgagactccatcaaccttacatgaccagaagcgctacataaggtatctttccgacctccatgcacctggtgaccctgcttggcagtgtattggagctcagcacaagtggaccctcaagctcatgcaagactgcaaagaaggccacatgaagagcctaaaaggtcacccaggcccgcacagccccatgctcgacctagacaacgatgtgcgcccctcggtgttgggccacctcagtcagacagcgtcactgaagagggggagcagctttcagtctggccgagatgacacatggaggtataagactccccacagagtggcatttgttgaaaaattaaccaagcttgtgttaagtcagctgcctaacttctggaaactctggatttcatatgttaatggaagtcttttcagtgagacggctgagaagtcaggccagagtgaaagatcaaagaatgtgaggcagagacaaaacgatttcaagaaaatgattcaagaagtaatgcactccctggtgaagctgatccggggagccctgcttccactcagcctccgagaaggggatgggaggcagtatggcggctgggaggtgcaggcagagctttcggggcagtggctcgcacacgttatccagaccataaggctaacatatgaatcactgaccgccctggagattcccaatgacatgttacagattatccaggacctaattttggatctccgaatacgttgcataatggtgacattgcagcatacggccgaagagataaagagattagctgaaaaagaagactgggttgttgataatgaaggactgacttccctaccatgtcagtttgaacagagcattgttcactccctgcagtccttgaagggtgttgtcgattgcaaacctggagaagccagcgtctttcaacagcctaaaacgcaggaggaggtttgccagttatgcatcaatatcatgcaggtttttatatactgcctggaacaactgagcaccaagcctgatgcagacatagatactactcatctttctgttgatgtttcttctcctgatttgtttggaagcatccatgaagacttcagtttgacttcagagcagaggcttttgatagtcctgagtaattgctgctatttagaacgtcacaccttcctaaacatagcagaacattttgaaaaacacaacttccagggaatagagaaaataacacaggttagcatggcatcgctgaaagaactggatcaacgactctttgaaaattacattgagctaaaagcagatcccattgttggatccttagaacctgggatctacgcaggctactttgattggaaggactgcctgcctccggcaggtgtcagaaactatttaaaagaagcattggtgaatataattgctgtgcatgcagaggtattcactatttccaaggaactggtgccacgggtcttggccagagtggtagaagcagtctctgaagagctgagccggctgatgcagtgcgtctcatccttcagcagaaatggagcactgcaggccagacttgaaatctgtgctctgagggacactgtagccatttacctgacctcggaaagcaggtctagttttaaacaggccctggaggccctgcctcagcttgcaagtggtgcggacaaaaagtcactggaagagctgctcaacaagttcaagagcagcatgcacttgcagctcacctgcttccaagctgcgtctccagcagtcatgaaaacataggctctgcaagaagagcatcagacatggcggtggagactgtcctcgtgctgtgcagcagagattacacgtcaagcactgcatttaacgtctcttttccccagcatggtggtgcagaaagatgcccatggatatttaatttcaatctatttaaactaccatagtttaaacatccaaataaacagtttttgttattgctagctttggtcctgaaaggctgtgtagcatactcttcaaaatgctgtgagtctggggatttctccatcatggtccagagcggcccatggtgtgtgtgtgtgcccttctcagtgcccctcttctaggcctactgttggcagtttccagcccaggtgagacatttgagaagagatttgaagtcacagtttttagagctttgtcctaaactttaaaataaccatttcatacaagtggttctaagctccccaccctgtttctgtaaagaaaaatatacagtctacacataaaaatgttaatatttggataaatttgtgatccacaagtcctcgtatgaactctgaatttcatagtctgactttcatttctcccagtgctaaacactgaagcttgtggttctcactcagccttaagctgatggatcactgcagtggtgtggggagggttcacaaggacctgtatgtggaggccctgtcacacccacaaggcctggggaaggcttgtggtcttcaatgcagcctaaagatgaagccaggctcctcggcaaggcagcactccctccccctctgccacttcccacgcggtgaaatgtcttgctccatagctggaaagaggctgctctggcatgggctgtgttttgtaaagatttgaggtgccccaagtgaccaggcactgagctgtgactcagtggtgagtggcttgcgcagtagagtcaggtcattgtgacctgcaggcagctttcacctcactccatccttccgtcagcctctgttgcacttcactcttcagactgatctgtggataatgtaggctcctcttctagagttgacaaaactaattccagagcacagcatatgtaccctgtggattatttaaggtaaatgagtgtatgtttatttatcacagtgactggaagtagaaattgtaatcctttgttgcaaaataagtatgtaccgcattgtctcctccctgtgtgctgttattatatctgacataaacaaactaaattccaaagcagaagtacagaaccatttgttattttaaacacctaataaatacagtgcacaaagccagtagttgtccttctctgtaagacccctatctttatttcaccatttttattagctctgtaattgcttatattcctgattttaaaatccacaataaatagtggagttctctctttta
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]