LOCUS       NM_001199902             664 bp    mRNA    linear   ROD 13-JAN-2022
DEFINITION  Mus musculus prefoldin 4 (Pfdn4), transcript variant 3, mRNA.
ACCESSION   NM_001199902
VERSION     NM_001199902.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Ewart-Toland A, Briassouli P, de Koning JP, Mao JH, Yuan J, Chan F,
            MacCarthy-Morrogh L, Ponder BA, Nagase H, Burn J, Ball S, Almeida
            M, Linardopoulos S and Balmain A.
  TITLE     Identification of Stk6/STK15 as a candidate low-penetrance
            tumor-susceptibility gene in mouse and human
  JOURNAL   Nat Genet 34 (4), 403-412 (2003)
   PUBMED   12881723
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL954701.10.
            
            On Jan 13, 2022 this sequence version replaced NM_001199902.1.
            
            Transcript Variant: This variant (3) uses an alternate in-frame
            splice site in the central coding region, compared to variant 1,
            resulting in an isoform (3) that is shorter than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048510.1, BU842167.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                AL954701.10        10052-10083
            33-140              AL954701.10        14353-14460
            141-269             AL954701.10        15176-15304
            270-664             AL954701.10        17287-17681
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 91.91 cM"
     gene            1..664
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="prefoldin 4"
                     /db_xref="GeneID:109054"
                     /db_xref="MGI:MGI:1923512"
     exon            1..32
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..401
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /codon_start=1
                     /product="prefoldin subunit 4 isoform 3"
                     /protein_id="NP_001186831.1"
                     /db_xref="CCDS:CCDS57190.1"
                     /db_xref="GeneID:109054"
                     /db_xref="MGI:MGI:1923512"
                     /translation="

MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEDAKKTLQEEIDALESRVASIQRVLADLKVQLYAKFGSNINLEADES"

     misc_feature    63..362
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="prefoldin subunit 4; Region: Prefoldin_4; cd23165"
                     /db_xref="CDD:467481"
     misc_feature    order(63..65,69..80,87..92,99..101,291..293,300..305,
                     309..314,321..326,330..338,342..350,354..362)
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="prefoldin/TRiC interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:467481"
     misc_feature    63..176
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="coiled coil [structural motif]; Region: coiled
                     coil"
                     /db_xref="CDD:467481"
     misc_feature    order(162..167,177..179,192..194,198..227,243..245,
                     255..257)
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="prefoldin oligomer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:467481"
     misc_feature    237..362
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="coiled coil [structural motif]; Region: coiled
                     coil"
                     /db_xref="CDD:467481"
     exon            33..140
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /inference="alignment:Splign:2.1.0"
     exon            141..269
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /inference="alignment:Splign:2.1.0"
     exon            270..664
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agtccaagatggcggccaccatgaagaaggcggctgcagaagacgtgaatgttactttcgaagatcagcaaaaaataaacaaatttgctcggaatacgagtcgaatcacagagctaaaggaggaaatagaagtgaagaagaacttagaggacgcctgtgatgacatcatgctggcagatgacgactgcttaatgattccctaccagatcggagacgttttcatcagccactctcaagaagaaacacaggaaatgttagaagatgcaaagaaaactttgcaagaagagattgatgccttagagtccagagtggcgtccatccagcgggtgttagccgacctgaaggtgcagctatacgcgaaatttggcagcaacataaacctcgaggcagatgaaagctaaacattttataatactttttttttatcttgttttaataaacttgaatattgtcttaaatgataatttcccttctccaaatgaaacaaaaggaaaactttcttttttaagaattttcatttaattaatggaaacgcctattttcacatgtcttgcttatttattttatatttttaaaagaagacagtgttcatgtatgtattttgcataatgattgtatcaattttaggagctttatgtcatgttattaaaatcggttaaacagt

//