LOCUS       NM_001085348             779 bp    mRNA    linear   ROD 07-AUG-2023
DEFINITION  Mus musculus reproductive homeobox 2E (Rhox2e), mRNA.
ACCESSION   NM_001085348 XM_001474270 XM_001474291
VERSION     NM_001085348.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 779)
  AUTHORS   MacLean,J.A. 2nd, Lorenzetti,D., Hu,Z., Salerno,W.J., Miller,J. and
            Wilkinson,M.F.
  TITLE     Rhox homeobox gene cluster: recent duplication of three family
            members
  JOURNAL   Genesis 44 (3), 122-129 (2006)
   PUBMED   16496311
REFERENCE   2  (bases 1 to 779)
  AUTHORS   Morris L, Gordon J and Blackburn CC.
  TITLE     Identification of a tandem duplicated array in the Rhox alpha locus
            on mouse chromosome X
  JOURNAL   Mamm Genome 17 (2), 178-187 (2006)
   PUBMED   16465597
REFERENCE   3  (bases 1 to 779)
  AUTHORS   Maclean JA 2nd, Chen MA, Wayne CM, Bruce SR, Rao M, Meistrich ML,
            Macleod C and Wilkinson MF.
  TITLE     Rhox: a new homeobox gene cluster
  JOURNAL   Cell 120 (3), 369-382 (2005)
   PUBMED   15707895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL808133.17.
            
            On or before Dec 27, 2007 this sequence version replaced
            XM_001474270.1, XM_001474291.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.318817.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                AL808133.17        10266-10360
            96-507              AL808133.17        10523-10934
            508-553             AL808133.17        19088-19133
            554-779             AL808133.17        21382-21607
FEATURES             Location/Qualifiers
     source          1..779
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 21.83 cM"
     gene            1..779
                     /gene="Rhox2e"
                     /gene_synonym="Rhox2.5; Rhox2d"
                     /note="reproductive homeobox 2E"
                     /db_xref="GeneID:100040016"
                     /db_xref="MGI:MGI:3770272"
     exon            1..95
                     /gene="Rhox2e"
                     /gene_synonym="Rhox2.5; Rhox2d"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..604
                     /gene="Rhox2e"
                     /gene_synonym="Rhox2.5; Rhox2d"
                     /note="reproductive homeobox 2D"
                     /codon_start=1
                     /product="reproductive homeobox 2E"
                     /protein_id="NP_001078817.1"
                     /db_xref="CCDS:CCDS53055.1"
                     /db_xref="GeneID:100040016"
                     /db_xref="MGI:MGI:3770272"
                     /translation="

MERQSVNYKLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPEFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL"

     misc_feature    428..586
                     /gene="Rhox2e"
                     /gene_synonym="Rhox2.5; Rhox2d"
                     /note="Homeodomain; DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:238039"
     misc_feature    order(434..436,554..556,563..568,575..577)
                     /gene="Rhox2e"
                     /gene_synonym="Rhox2.5; Rhox2d"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     exon            96..507
                     /gene="Rhox2e"
                     /gene_synonym="Rhox2.5; Rhox2d"
                     /inference="alignment:Splign:2.1.0"
     exon            508..553
                     /gene="Rhox2e"
                     /gene_synonym="Rhox2.5; Rhox2d"
                     /inference="alignment:Splign:2.1.0"
     exon            554..779
                     /gene="Rhox2e"
                     /gene_synonym="Rhox2.5; Rhox2d"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gaataaggacttccacggctttacagacatggagcgacaaagcgtcaattacaagcttgatgtgggacctgaggaggatgaggaaaatgcgaatggtgtaaagactctgatggtcttgctggctggagagggaagaaacgagggagagagtggacggggcctgcctgggtcgggagcctcagcagcggaaggatacagagcaggagaaataagtgcaggtgggcctgctgcgccagtagccgacctcatggataacagcaaccaagaggaccttggtgccactggctgtgaccaggagaaggagaagcagccagaggagccagtccctgattccatgggagatttggaaaatgtaaagcgtgtgtccgggccgtggtccactgttaatcctgtgagagtgttggtgcccgaattccgccacggttggcaacagagcttcaatgtgctgcaactacaagagctggagagcatcttccagtgcaatcactacatcagcactaaggaggcaaatcgcctggcaagatccatgggagtgagtgaagccacagtgcaggaatggtttttgaagaggagagaaaaatacaggagttataagaggctgtaaatgctcagaggtcctcttcctgcttcccacagcatctctctgtgaaggctatggagaagccccagggatccacgcttcctcaaggcgccatagccagacgatgttttcccgccaaagtcctgttacaacacagttatctcctcaatacttgtattagcaataaagagctgaattc

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