LOCUS       NM_001013369             816 bp    mRNA    linear   ROD 13-JAN-2022
DEFINITION  Mus musculus prefoldin 4 (Pfdn4), transcript variant 2, mRNA.
ACCESSION   NM_001013369 XM_355370
VERSION     NM_001013369.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 816)
  AUTHORS   Ewart-Toland A, Briassouli P, de Koning JP, Mao JH, Yuan J, Chan F,
            MacCarthy-Morrogh L, Ponder BA, Nagase H, Burn J, Ball S, Almeida
            M, Linardopoulos S and Balmain A.
  TITLE     Identification of Stk6/STK15 as a candidate low-penetrance
            tumor-susceptibility gene in mouse and human
  JOURNAL   Nat Genet 34 (4), 403-412 (2003)
   PUBMED   12881723
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL935134.10 and AL954701.10.
            
            On Jan 13, 2022 this sequence version replaced NM_001013369.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR, lacks a
            portion of the 5' coding region, and uses a downstream start codon,
            compared to variant 2. The encoded isoform (2) is shorter at the
            N-terminus, compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC065407.1, AW990012.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-172               AL935134.10        98658-98829
            173-280             AL954701.10        14353-14460
            281-421             AL954701.10        15164-15304
            422-816             AL954701.10        17287-17681
FEATURES             Location/Qualifiers
     source          1..816
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 91.91 cM"
     gene            1..816
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="prefoldin 4"
                     /db_xref="GeneID:109054"
                     /db_xref="MGI:MGI:1923512"
     exon            1..172
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    71..73
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="upstream in-frame stop codon"
     exon            173..280
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /inference="alignment:Splign:2.1.0"
     exon            281..421
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /inference="alignment:Splign:2.1.0"
     CDS             320..553
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="prefoldin subunit 4 isoform 2"
                     /protein_id="NP_001013387.1"
                     /db_xref="CCDS:CCDS50808.1"
                     /db_xref="GeneID:109054"
                     /db_xref="MGI:MGI:1923512"
                     /translation="

MLADDDCLMIPYQIGDVFISHSQEETQEMLEDAKKTLQEEIDALESRVASIQRVLADLKVQLYAKFGSNINLEADES"

     misc_feature    <320..523
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /note="Prefoldin subunit; Region: Prefoldin_2; pfam01920"
                     /db_xref="CDD:396482"
     exon            422..816
                     /gene="Pfdn4"
                     /gene_synonym="0610025M10Rik; 1810063B06Rik; C-1; C1;
                     Pfd4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

cgagctgctgacctgagctccccctgccaccccgaccggaaggaatagggaacaggggacaataggtgattaggaaacaaactatttaccagtgtgtcgtgctgtttcttcaggccacctttccaaaaaatctccagtaggctgcccagcagtggccagttggtgggtccaggctgcagaagacgtgaatgttactttcgaagatcagcaaaaaataaacaaatttgctcggaatacgagtcgaatcacagagctaaaggaggaaatagaagtgaagaagaaacatctccagaacttagaggacgcctgtgatgacatcatgctggcagatgacgactgcttaatgattccctaccagatcggagacgttttcatcagccactctcaagaagaaacacaggaaatgttagaagatgcaaagaaaactttgcaagaagagattgatgccttagagtccagagtggcgtccatccagcgggtgttagccgacctgaaggtgcagctatacgcgaaatttggcagcaacataaacctcgaggcagatgaaagctaaacattttataatactttttttttatcttgttttaataaacttgaatattgtcttaaatgataatttcccttctccaaatgaaacaaaaggaaaactttcttttttaagaattttcatttaattaatggaaacgcctattttcacatgtcttgcttatttattttatatttttaaaagaagacagtgttcatgtatgtattttgcataatgattgtatcaattttaggagctttatgtcatgttattaaaatcggttaaacagt

//