LOCUS       NM_001001130            2286 bp    mRNA    linear   ROD 16-OCT-2021
DEFINITION  Mus musculus zinc finger protein 85 (Zfp85), mRNA.
ACCESSION   NM_001001130
VERSION     NM_001001130.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2286)
  AUTHORS   Krebs CJ, Larkins LK, Price R, Tullis KM, Miller RD and Robins DM.
  TITLE     Regulator of sex-limitation (Rsl) encodes a pair of KRAB
            zinc-finger genes that control sexually dimorphic liver gene
            expression
  JOURNAL   Genes Dev 17 (21), 2664-2674 (2003)
   PUBMED   14563677
REFERENCE   2  (bases 1 to 2286)
  AUTHORS   Marine JC, Gilbert DJ, Bellefroid EJ, Martial JA, Ihle JN, Copeland
            NG and Jenkins NA.
  TITLE     Chromosomal location of fifteen unique mouse KRAB-containing zinc
            finger loci
  JOURNAL   Mamm Genome 7 (6), 413-416 (1996)
   PUBMED   8662221
REFERENCE   3  (bases 1 to 2286)
  AUTHORS   Bellefroid EJ, Marine JC, Matera AG, Bourguignon C, Desai T, Healy
            KC, Bray-Ward P, Martial JA, Ihle JN and Ward DC.
  TITLE     Emergence of the ZNF91 Kruppel-associated box-containing zinc
            finger gene family in the last common ancestor of anthropoidea
  JOURNAL   Proc Natl Acad Sci U S A 92 (23), 10757-10761 (1995)
   PUBMED   7479878
REFERENCE   4  (bases 1 to 2286)
  AUTHORS   Ihle JN, Smith-White B, Sisson B, Parker D, Blair DG, Schultz A,
            Kozak C, Lunsford RD, Askew D, Weinstein Y et al.
  TITLE     Activation of the c-H-ras proto-oncogene by retrovirus insertion
            and chromosomal rearrangement in a Moloney leukemia virus-induced
            T-cell leukemia
  JOURNAL   J Virol 63 (7), 2959-2966 (1989)
   PUBMED   2542606
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV658296.1, BK001637.1 and BC055337.1.
            
            On Feb 7, 2019 this sequence version replaced NM_001001130.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.5023495.1, BC055756.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-650               DV658296.1         39-688
            651-2027            BK001637.1         587-1963
            2028-2286           BC055337.1         1960-2218
FEATURES             Location/Qualifiers
     source          1..2286
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 34.74 cM"
     gene            1..2286
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="zinc finger protein 85"
                     /db_xref="GeneID:22746"
                     /db_xref="MGI:MGI:107767"
     exon            1..140
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    15..17
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="upstream_AUG_codon; putative N-terminal extension:
                     MTPLDRTLLSVLPGSFYVCDSPNSAVFSKLGQCGLFFALN"
     CDS             135..1556
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="KRAB-zinc finger protein 71; regulator of
                     sex-limitation candidate 2; zinc finger protein 85,
                     related sequence 1"
                     /codon_start=1
                     /product="zinc finger protein 85"
                     /protein_id="NP_001001130.1"
                     /db_xref="CCDS:CCDS36717.1"
                     /db_xref="GeneID:22746"
                     /db_xref="MGI:MGI:107767"
                     /translation="

MKDLLSFTDVAIDFSADECECLDSAQWNLYKEVMLENYSNLVFLGLAFSKPYLVTFLEQSSDPWSMKRKESAAIHLGSKPHKCKECGKAFDRNSVLIQHQRIHTGERSYKCEECGKSFNYSSSFKQHQRIHTGEKPYKCEVCGKAFNCSSYLGKHQRIHTGEKRYKCEECGKPFTNCSGLIVHRRVHTGEKPYKCEECGKAFSVGTTLSNHQRIHTGEKPYKCEECGMAFNVRFLLSKHQQTHTGEKPYKCKECGKAFNCSSSLHQHQQIHRGEKLYKCDDCGQAFSCSSYLYKHRRIHTGMKPSKCKECGKTFYCSVNLIYHQRIHTGEKPYKCNECGKAFSIYSRFMKHQRIHSGEKPYKCKECEKAFNNCYNLIQHQRIHTGEKPYKCKDCGKAFHYTSSLAQHERIHTGEKPYKCEECGKAFNSSSNLKNHWRLHTGEKPYKCEQCGKAFKDCSSFTRHYRIHTRENPD"

     misc_feature    147..329
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="krueppel associated box; Region: KRAB; smart00349"
                     /db_xref="CDD:214630"
     misc_feature    375..>527
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="N-terminal domain of Oryza sativa transcription
                     factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana
                     SUF4 (AtSUF4), and similar proteins; Region: SUF4-like;
                     cd20908"
                     /db_xref="CDD:411020"
     misc_feature    381..446
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:411020"
     misc_feature    381..443
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    order(396..398,402..404,408..410,414..419,426..431,
                     438..440,480..482,486..488,498..503,510..515,522..524,
                     564..566,570..572,576..578,582..587,594..599,606..608)
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:275368"
     misc_feature    order(396..398,414..416,435..437,441..443,462..464,
                     483..485)
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="putative DNA binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:411020"
     misc_feature    453..1550
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="FOG: Zn-finger [General function prediction only];
                     Region: COG5048"
                     /db_xref="CDD:227381"
     misc_feature    465..527
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:411020"
     misc_feature    465..527
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    549..611
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    633..695
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    717..779
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    801..863
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    885..947
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    969..1031
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1053..1115
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1137..1199
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1221..1283
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    order(1236..1238,1242..1244,1248..1250,1254..1259,
                     1266..1271,1278..1280,1320..1322,1326..1328,1338..1343,
                     1350..1355,1362..1364,1404..1406,1410..1412,1416..1418,
                     1422..1427,1434..1439,1446..1448)
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]; other site"
                     /db_xref="CDD:275368"
     misc_feature    1305..1367
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1389..1451
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     misc_feature    1473..1535
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /note="C2H2 Zn finger [structural motif]; Region: C2H2 Zn
                     finger"
                     /db_xref="CDD:275368"
     exon            141..267
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            268..363
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            364..2286
                     /gene="Zfp85"
                     /gene_synonym="KRAB19; Rslcan2; Zfp71; Zfp85-rs1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ctctctctttctgtatgaccccgctagacaggactctgctctctgtgcttccgggttctttttacgtttgtgattctccaaactctgcggtgttctcaaagttgggacagtgtggcttgttcttcgcgcttaacatgaaggaccttctgtcattcacagatgtggccattgatttctctgcagatgagtgtgaatgtctggactctgctcagtggaatttgtataaggaagtgatgttggagaattacagcaaccttgtgttcctgggtcttgctttctctaagccatacctggtcacatttctggagcagagttcagatccgtggagcatgaagaggaaagaatcagcggccatccatctaggatcaaaaccccataaatgtaaagagtgtgggaaggcctttgataggaactcagtccttattcagcatcaaagaatacatactggagagagatcctataaatgtgaagaatgtggcaaatcatttaattattcttccagctttaaacagcaccaaagaattcatactggcgagaaaccctacaaatgtgaagtgtgtggcaaagcttttaactgttcttcatatctgggtaagcatcaaagaatccacactggagagaaacgctacaaatgtgaagaatgtggtaaaccttttactaattgttcaggacttattgttcaccgaagagtacatactggagagaaaccctacaaatgtgaagaatgtggcaaggcctttagtgttggcacaacactctctaaccatcagagaattcacactggagagaaaccttacaaatgtgaagaatgtggtatggcctttaatgttcgctttcttctttctaagcaccagcaaactcatactggggagaaaccctacaaatgtaaagaatgtggcaaagcttttaactgttcttccagccttcaccaacaccaacagattcataggggagagaaactctataagtgtgatgactgtgggcaggcctttagctgttcatcatatctgtataagcatcgtcgaatccatactggcatgaaacccagcaaatgcaaggaatgtggcaagactttttactgttctgtaaatcttatttaccaccagagaattcatactggagagaaaccatataaatgtaatgagtgtggaaaagcttttagcatttactcaagatttatgaaacaccagcgaatacatagtggagaaaaaccctataaatgcaaagaatgtgagaaggcctttaataattgttataatctaattcaacaccaaagaattcatactggagagaaaccctacaaatgtaaagactgtggcaaagcctttcattatacttcaagccttgctcaacatgaaagaattcacactggagagaaaccctacaaatgtgaagaatgtggcaaggcctttaactcttcttcgaatcttaaaaatcattggagactccatactggtgagaagccttacaaatgtgaacaatgtgggaaagcctttaaagactgttctagctttactcgacactatagaattcatactagagaaaacccagactagctcaaccatgtcgcaaagtcttccataatcatttactgataattctacactaaaaaaattcatatgagaaggaaaggaacaagggaagaccgttaataatagctcagcccttatttaccctcttccattaaatgcaggaaagatcttataatgtgaagaagatggccgtgatgagcaatctatacttatgcagcatcaaaattttcattttacagaaactctgcaaatgcaagtattgtgggaaatgcacactcagtaccagtgaattataataactgtatacatgcataatgactcaggaaggaacactgtcaagtacataaaactgagacaaccgaactcttacagtgagaagcactgtgtacactgtgttgcaagagcacatggatcttaagagatataagagacaaattccaggagttgtagagaatttagccaaggaataaatactgcttataatcggcaggaaaatgtttggtgtaatataaaaactcattacacactttagatcatgcagataagtctgtgaggacatcagtatgttataaatccaaattataacctcagttttgtcaagtgaaaagaacacaaggactagtgattttatcagaagaacaagactgagtcctgaggtttccgagtccttttttttccccaaagaccatatatacattattggaatatgaagtttagtaacttttgtaaataaaaagaagctgtttttaatgta

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