LOCUS       XM_068672721           13698 bp    mRNA    linear   VRT 22-SEP-2024
DEFINITION  PREDICTED: Anas acuta argonaute RISC catalytic component 2 (AGO2),
            mRNA.
ACCESSION   XM_068672721
VERSION     XM_068672721.1
DBLINK      BioProject: PRJNA1122813
KEYWORDS    RefSeq.
SOURCE      Anas acuta (northern pintail)
  ORGANISM  Anas acuta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes;
            Anatidae; Anatinae; Anas.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_088980) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963932015.1-RS_2024_09
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 09/19/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13698
                     /organism="Anas acuta"
                     /mol_type="mRNA"
                     /db_xref="taxon:28680"
                     /chromosome="2"
     gene            1..13698
                     /gene="AGO2"
                     /note="argonaute RISC catalytic component 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 28 Proteins"
                     /db_xref="GeneID:137851528"
     CDS             328..2919
                     /gene="AGO2"
                     /codon_start=1
                     /product="protein argonaute-2"
                     /protein_id="XP_068528822.1"
                     /db_xref="GeneID:137851528"
                     /translation="

MYPGATSAGPVLAPPPPMPPPIQGYAFKPPPRPDFGSSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVAIKWMSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"

     misc_feature    613..837
                     /gene="AGO2"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    865..1017
                     /gene="AGO2"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    1018..1380
                     /gene="AGO2"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1174..1176,1219..1221,1261..1263,1273..1275,
                     1327..1329,1348..1350,1354..1356)
                     /gene="AGO2"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1513..2790
                     /gene="AGO2"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1924..1926,1936..1938,1972..1983,1990..1992,
                     2014..2016,2023..2025,2035..2037,2047..2049)
                     /gene="AGO2"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2128..2130,2134..2136,2344..2346,2758..2760)
                     /gene="AGO2"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      13698
                     /gene="AGO2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

cgcagccggccccacagccggggccgcggggcccctcaggcggcgcccgccctgcttcccgctcgccgcgggggctgagggagggaggcgggcagcaggcggggcgccccttccccgtgaccccacagctcctcccttctccccgctcctcagggccgccgagtaacctggttttaacgcgggccctcctccttttttttttttttttccctttttcttttcctcctccctttccccccccctcccttctcttccagcgttaagcgcggctcgggctgctccctttccctccctttccctcccctcgcagccgcctcacacggagacatgtacccgggagccacctccgccggacccgtgctcgcacctcctccaccaatgccaccaccaatccagggatatgccttcaaacctcctcctcgcccagatttcggctcttctgggagaacaatcaaactgcaggccaacttctttgaaatggacattcccaaaattgatatctaccattatgagttggacataaagccagaaaaatgccccagaagagttaacagggaaatagtggagcatatggttcagcactttaaaacacagatctttggggatcgcaagccagtgtttgatggaagaaaaaacctttatacagctatgccgcttcccattggaagagataaagtggagctggaggtcacgctgccaggagaaggcaaggacaggatatttaaggtggcaatcaagtggatgtcctgtgtgagcttgcaggctttacacgatgctctttctggccggcttccgagcgtcccgtttgaaaccatccaggctctggatgtggtgatgaggcacttgccttccatgagatatactcctgtggggcgatctttttttacagcatcagaagggtgctccaatccattaggtggtggcagagaggtttggtttggattccatcaatcagtcagaccttccttatggaaaatgatgttaaatattgatgtatctgcaactgcattttacaaagcacagccagttattgagtttgtatgtgaagttttggacttcaaaagtattgaagaacaacaaaaacctctgacagattcccaaagggtaaagtttaccaaagaaataaaaggtctgaaggtggagataacacactgtggacaaatgaaaagaaaatacagagtgtgcaatgtcaccagacgaccagcaagtcaccaaacattcccgcttcagcaggagaatggacaaacagttgaatgcactgtagctcagtattttaaggacaggcacaaattagttttgcgctatcctcacctcccatgtttacaagttggacaggagcagaagcacacgtaccttcctctggaggtgtgcaacatagtggcaggacaaagatgcataaaaaagctcaccgacaatcaaacttccactatgattcgagcaactgccagatcagcacctgaccgtcaggaagagattagcaaattgatgcggagtgcaagtttcaatactgacccttatgttcgtgagtttgggataatggtcaaggacgaaatgacagatgtgactggtagagtcctgcagcctccctcaatcctctacggaggcaggaataaagcaattgctacgccagttcaaggagtttgggacatgaggaataaacagtttcacactggaattgaaataaaggtttgggcaatcgcttgctttgctccccagcgccaatgcactgaagttcatcttaagtcctttacggaacagctgaggaagatttccagagatgcaggaatgccaatccaagggcagccgtgcttctgtaaatacgcccagggagccgacagcgtggagcccatgttcagacatctcaagaacacttacaccggcctgcagcttgttgtggtgattttgccaggaaagacaccagtctatgcggaggtgaagcgtgttggtgacaccgtgctgggaatggctacgcagtgtgttcagatgaagaacgtgcaaagaacaacaccacaaactctgtccaacctctgcttaaaaataaacgtcaaattaggaggtgtaaataacattttactgccacagggaagaccaccagtatttcaacagcctgtcatattccttggtgcagatgtaactcatcctccagctggggatggaaaaaagccttccattgctgcagttgtaggaagcatggacgctcaccctaatcgatactgtgccactgttcgggtccagcagcaccgccaagaaatcatccaagatttggctgccatggtcagggagttgcttatccagttctacaaatcaaccagatttaaaccaactcgtatcattttctacagagatggcgtttccgaggggcagtttcaacaggttctccatcatgaattgctggctatcagagaagcatgcattaaactagaaaaggattaccagcctggaattacattcatagttgtgcagaaaaggcatcacaccagactcttctgtacagataaaaatgaacgggttggaaaaagtggaaacattcctgctggcaccacagtggacacaaaaatcacccatccatcagagtttgacttctacctgtgtagtcatgctggtattcagggaacaagcagaccttcgcattaccacgtcctctgggatgacaatcgtttctcttcggatgagctgcagattctcacctaccagttgtgtcatacgtacgtacgctgcacccggtcggtttccatccctgcgcctgcctattacgcgcacctggttgccttccgagccaggtaccatctggtggataaagaacacgatagtgctgaaggcagccacacttcgggtcagagtaatggcagagatcatcaagcacttgctaaagcagttcaagttcatcaggacacgttgcgcactatgtactttgcttgacatgttttaatgtttagcgactcagtacaatagagagttggattcacatgagaccagctgcacttagaccaacagttgcccaagctacagtgacagccagccatgagggacgcctcttaatttctttcccatttgcaaagaaagccttccgtccagaatttcagacttgattgtgaactgcgttcttgtaccaaaccccacgattgttggaaatgtggtttgccaaaatctctaagctgtctgttataaaacagacccatattttataattgaaccaagagctgtgatctcagggcttagggaaaaacaaaacaaagcaacaaaacaccgacctcttcgttcagtttgctattcatttaaccgcttttaataatttggagagatctaattcatactcaagttggtgggcaaaaatgctgtgaattagcttttaatacaaagaaaaagcaaagcgttttttggctctttatgaagcctctattattctagatgcatttacaaaatgtttattttcaaaagagtgacaaaatcctggttttcaactgtcttacaaagattgttctctctgtgtctaagggcaaatgtattttctgaagcttgtttcttgaatgttttttattgtgctgcatttaaaaatgttttttcatagactaaagaagaatttaaaaaaaaaaaagaaacaaactcgtacctaaacttttaataggtccagttagattggcaagacgtgccatttttgagaagcaaaaattgtaaaggatttttttaatcacactgacagctaactttagaatttgtcatacaggactgtgacacttactttccaaagtctctaaggaatacgggtctgtggtgataaaatacagtacaatcttctttcactgttatgtttgaattaatgtaaattttatatatgtttcacagtattaatgtgatagactagatgctattatttatttttatttactaaggagtgctcattatgcttctgttaacatatcaagaatgctttggatttagaaattaaaaccttctcgtgaggacattactcttcaaatgcaaaaaaaaaaaaaaatatgcaactgactttgtgagagctcagagatacgtgcagtgtgtgttgtggagcttgtaatgtgtagaagggcttttcgagcgtgcacacagcagagcagggtttacctgtgccgttcagagacgcacacgagaccaacattctgtattttcaagcacaaaacacttgtttttttttatttatgtgttggttactggcgaagcgggcgctctgggagaggagagtggttcactgttggtgattttagacagaagtcagagaatctatgcagtaaagataaatcttaggaaactgaagtttacttttgaagggaggggaagctctcttcattatgcataaggtcaatggtaaatgtgagagttttgccattctcttcggagaagcattaattaaagctgataattgttagacaaacgcttctgttagtttgcacactgggttcagaagaaaaccataatccatatggaaaccattgcactaattacaatgccacaagcaggtttaggaggaaatgttaaaagcccaggaaatgttgatgttgacttgattttgttcgtcgtcataggataacttaaatacattggtaagaggcaggttgtgaaaatgtccttctcttccatttttgcgttgtcttttcccctttttctcttagcagaagctcagtcactgctctgagtccgtttacctctagccactgaggcgggtgcgtagctttaacccccgcggagctctgtgccatatagcagagggactaaacctggttgctgtcgaataagctagaaaatgcccgagctgtgctgcaaaaagagctgtaggtacataacttcgtacacctcgtagtgttgattgtcagtggtgtttaggtgaaataacgcgaatcctagtaacagaggagtggtgtttgtggtgttctcattccttgattgggctgctgggtcagattttcttcttggtcagttttgtaaacctagattattatttttttttttaaatgacgctggtgtaa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