LOCUS       XM_054571963            6326 bp    mRNA    linear   MAM 01-APR-2024
DEFINITION  PREDICTED: Pteronotus mesoamericanus argonaute RISC component 4
            (AGO4), mRNA.
ACCESSION   XM_054571963
VERSION     XM_054571963.1
DBLINK      BioProject: PRJNA947226
KEYWORDS    RefSeq.
SOURCE      Pteronotus mesoamericanus
  ORGANISM  Pteronotus mesoamericanus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera;
            Mormoopidae; Pteronotus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_026555092) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_021234165.1-RS_2024_03
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 03/28/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6326
                     /organism="Pteronotus mesoamericanus"
                     /mol_type="mRNA"
                     /isolate="MK-2021"
                     /db_xref="taxon:1884717"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="liver"
                     /dev_stage="adult"
                     /breed="Mesoamerican mustached bat"
     gene            1..6326
                     /gene="AGO4"
                     /note="argonaute RISC component 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 28
                     Proteins"
                     /db_xref="GeneID:129069305"
     CDS             68..2653
                     /gene="AGO4"
                     /codon_start=1
                     /product="protein argonaute-4"
                     /protein_id="XP_054427938.1"
                     /db_xref="GeneID:129069305"
                     /translation="

MEALGPGPPTSLFQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA"

     misc_feature    143..532
                     /gene="AGO4"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    563..715
                     /gene="AGO4"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    716..1078
                     /gene="AGO4"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(872..874,917..919,959..961,971..973,1025..1027,
                     1046..1048,1052..1054)
                     /gene="AGO4"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1217..2524
                     /gene="AGO4"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1628..1630,1640..1642,1676..1687,1694..1696,
                     1718..1720,1727..1729,1739..1741,1751..1753)
                     /gene="AGO4"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1832..1834,1838..1840,2078..2080,2492..2494)
                     /gene="AGO4"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

ggcggcggcggcggggcccggagcgggaggcgccggggaccggggcgaggcggcccccgccgccgccatggaggcgctgggaccaggacctccaaccagcctgttccagccacctcgtcgtcctggccttggaactgttggaaaaccaattcgactgttagccaatcattttcaggttcagattcctaaaatagatgtatatcactatgatgtggatattaaaccagaaaaacggcctcgtagagtcaacagggaggtagtagatacaatggtgcggcacttcaagatgcaaatatttggtgatcggcagcctggctatgatggcaaaagaaacatgtacacggcacatccactgccaattggacgggatagggttgatatggaagtgacccttccaggtgagggtaaagaccagacctttaaagtgtctgttcagtgggtgtcagttgtgagccttcagttgcttttagaagctttagccgggcacttgaatgaagtcccagatgactcagtacaagcacttgatgttatcacaagacaccttccctccatgaggtacactccagtgggccgttcctttttctcacctccggaaggttactaccaccctctgggagggggcagggaggtttggtttggctttcaccagtctgtgagacctgccatgtggaatatgatgctcaatattgatgtatctgcaactgctttctaccgggctcagcctatcattgagttcatgtgcgaggttttagacattcagaacatcaatgaacagaccaaacctctaacagactcccagcgtgtcaagtttaccaaagaaatcagaggtcttaaagttgaggtgactcactgtggacagatgaaacgaaaataccgagtttgtaatgtgactagacggccagccagtcatcaaacttttcctttacagctagaaaatggtcaagctatggaatgtactgtagctcaatattttaagcaaaagtatagtctgcagctgaaatatccccatcttccatgtctccaagtaggacaagaacaaaagcatacgtatttgccacttgaggtctgtaatatagtggcaggacagcgatgtataaagaaactcacagacaatcagacttccacgatgatcaaagccacagcaagatctgctcctgacagacaggaagaaatcagtagactggtgaagagtaacagcatggtgggtggacctgatccataccttaaagaatttggtattgttgtccacaatgaaatgacagagctcacaggcagggtacttccagctccaatgctacaatatggaggccggaataaaacagtagccacacccaaccagggtgtctgggacatgcgaggaaagcagttttatgctggcattgaaattaaagtttgggcagttgcttgttttgcgcctcagaaacaatgtagggaagatttactaaagagtttcactgaccagctccgtaaaatctctaaggatgcagggatgcccatccagggtcagccatgtttctgcaagtatgcacaaggtgcagacagcgtggagcccatgtttaaacatctgaaaatgacctatgtgggcctgcagctgatagtggtgatcttgcccgggaagacgccagtatatgcggaggtgaaacgtgttggagataccctcctgggtatggccacacaatgtgtccaggtgaaaaatgtagtgaagacctcaccacagaccctttccaacctttgtctgaagataaatgcaaagcttggaggaattaacaacgtgctcgtacctcatcaaaggccatcggtgttccagcagcccgtcatcttcctgggagcggatgtcacacacccgcctgcaggagacgggaagaagccttctattgctgctgtcgttggcagcatggatggccatcccagccggtactgtgcaaccgttcgggtgcagacttcccgccaggagatctcccaggaactcctgtatagtcaggaagtaatccaggaccttactaacatggttcgagagctgctgatccagttctacaaatccacacgcttcaaacccacacggatcatctattaccgtggaggggtgtccgagggacaaatgaaacaggtagcttggccagaactaatagcaattcgaaaggcatgtattagcttggaggaagattaccggccaggaataacctacattgtcgtacagaaaagacatcacacacgactcttctgtgcagataaaacagaaagggtgggcaaaagtggcaatgtaccagcaggcactaccgtggatagcaccatcacacatccgtctgagtttgacttttacctctgtagtcatgcaggaattcagggaaccagccgtccttcacattaccaggtcttgtgggatgacaactgcttcaccgcggatgagctccagctactgacttaccagctatgtcacacctatgtgcggtgtacacgctcagtctctattccggcccctgcatattatgcccggcttgtcgcattcagagcaaggtatcatctggtggataaagatcatgacagtgcagaaggcagtcatgtgtcaggacagagcaatggccgagatcctcaggccttggctaaagctgtgcagatccaccatgatacccagcacacaatgtattttgcctgagagtctcagaagaactcaaccaactgggcaccccatgcagcctcaaaatgtttcacatgcctactgcctctagagagagccaagttgacttcagtttgtcttctaccagcagctcggaatagttgcactgaataaatattttgcagcactgtctgatgcatcaacaaaattgagccatttttaaaaagtaatagatattcatagattgtcttttctgatgcactggactgaatttttacctcaacatgcaaaggctagtcagcctgaactttctaaaggactttacaagaaaggtttctatggaatattttgctagctgtggtgttcactgcatccctctagtcttataagagaagattattccttttttctgtattcatcgagtgggatgtatgcatcagtggaagagaaaaaccaaacaatctacttcagtttagtgaaactatttaattatgtgggtccatagactttttaatggagatttctgactttgccactgtaaatgcctttaacgagcattaatttttgaaagttttacagagttttattagttttactactttatcttattgatctctacagtcttgtgctggtgcgagtacaggctgccaggcaattgcactatatttggctcccgatttaaacaggcagttctcttatttggtcgacacttgtgaatgtgtaacgcacacagatgtaatgcatgtcacagtgacaaataacactgccgtggtaaaaagtactcatgttttccccctctttgaaaaaagctagcttttagtatttttcagagttttcaaaagtgcccattttatgctgctctgtggttcgtcagatccaaatgatttttaaacttttctcatagaaagttaactggcaataaacatttttaaggtcccttcactccatttcccccaccctcagcaatgagttttctagatgaaatcttggtatgattttatcagctatttcttataaatcataatctggcaattcctgaaatcagtcagaaaaaacgtatatttccatgtctttttaaagaattattttttatctcttttatagtcacagttggtatcctctcactttgttttaaaataagctagaatcaggatgcttccttactggataggctttgccaatcctgtaggtaccttgagtgatgctgcaacttgcaaaaaatgtaccagcatttaaaactttttcctgggaatcaaggttacttacacaattacttaagtgcagtgcaaatgttgtgcttctctttcaacctgaaatgtacttggtgaggtttccttccttttagtaaagcaaaaacttcataaaaaggttgattttttttttttcttaatagattctggattctgttcacagggagacaggattaatttcttgtccatacaaagggagttgatataaagcaagcatcagtgacagtgtcggggaaactcttttgtatttagtatagataatactttgtgaatggacaacagttacatagagtcttgctggttctagccagtgttgcccagaccagatttcactgacatacagttctctatcctggaacgtcaagagtcagagctgggaaagggggtaaaagactcggagccacactccacgtgggtgaggaaggtgctgggagaagagacagacacaatatggtaaaccgaatttgtcacctctgtctggaaacactggatctgatggtgaagggtgtttgctcgaactcattagtcggtccaaatcttttaaactagccttctcaaaatcccagcaatagaaagccctgtttttcttcagtcttttaaacaagcttgtaaatacattgaagtttacatttctatatgctgttgatcagcggcgccaccagtatttgctgggactggtctttgagagttttagtataatgtatatcgagttctgtagctcatgaagatgggtgcagcagacatccttattctctgcatataatgagaggaaagaaagcaagctctgtaattgaggcacaacatagtgaagagatggcagttgttaatttcttaagattttccttttgttcaaatacctcacttggatactacaaatcaggacatgttggtgaggggctggctactgcttttattcacacctgttcagggagagcacagaaaatacccttcagcatggccaccctggacccaagaggaggaaaaacaagctttttttaggaggaggattcactggagtccaggatgtgaagaacttggggtggctggctggctggctggccggccagcgggccccacacctgcacttgagtgcctcgggcttgcttgttcacgcactgaagaagcgtcacttctcaccatctccgggcatgaacggagcagggagcaaggcggagtgcctggaagccctgattcgcttgcctgcagttgggctctgtgctcgaccttgaactctacagtttgtatgacctcagtcactcctagtacactggggcaaatccctgtggtggtggaggaaaagccgggaggcctatttttataggaaaacagtaccttcaagggtgcaacgctgtcattttggaggaaaggaaagaaatatggaagaactaggattattggggggggaaaccttgttgaggggtgaacctttaacaagtaatcactgcagaatcagagttgcagcaatgctattgcaagcaagtctgaatgcgtagttttaattgggcctgacaatttgaatttgtaaccctctggactgactgaattgttatgcatgtgtcaatcaatgggaggtgtgcattctttagaagtaggtttaggatgcttggttttttaaacgcagcctgtttaggccctgtcatgtagtgtgaaagatttaaatgtagcaatgctaaagagtaacaatttagggacaaggtgcggggacattaagagagcggtgaagatccaaatgttgaaccggttatgttttttgttagctgttgaaccctgagcaatttataaagagaactagctggcttaacacagctagttgaggcaggcagaacatactcatccttactgtaaattctatttgctgcttccaaaggtgatgatttacaagcagacatattctgtatggtctgtattttaggacctggtgcccagcctatatcagagcttagctacctggctcaactacctacccttctggtggggaacggtaatctactgtttaacaaggctcaccctctccaccctgccctagcgaccctttgtggatgtgctgtaagattttcttgctcaatagcaaggtggtaactctgctttcattttaagaaagtggaggttgagggcattgtatcaatacggcttcaactccaaggattttcccttgtaaaattaaagggaagatcttgttattgattaatcattttcttatcccttgctattgacatattcatgctctttctatgtctagtgactgaaaatgtttgcatttgttcatttaactaatggtgtaatttttgtttctatattgttagacctgtaatgttttaaaatgtattttattaaatttggactggatgtatatctctagcaatacgaggtactttctaaactaatggaggatggtatccccatgttgaaataagatgatggttgtttaaattttgcaatttcttttttttttttttttggcc

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