LOCUS       NM_001400627            3101 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus RecQ mediated genome instability 1 (Rmi1),
            transcript variant 2, mRNA.
ACCESSION   NM_001400627 XM_039096369
VERSION     NM_001400627.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3101)
  AUTHORS   Suwa,A., Yoshino,M., Yamazaki,C., Naitou,M., Fujikawa,R.,
            Matsumoto,S., Kurama,T., Shimokawa,T. and Aramori,I.
  TITLE     RMI1 deficiency in mice protects from diet and genetic-induced
            obesity
  JOURNAL   FEBS J 277 (3), 677-686 (2010)
   PUBMED   20050919
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Jan 26, 2022 this sequence version replaced XM_039096369.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643288.56656.1,
                                           SRR26643291.38813.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-235               JAXUCZ010000017.1  6269017-6269251     c
            236-831             JAXUCZ010000017.1  6266653-6267248     c
            832-916             JAXUCZ010000017.1  6265095-6265179     c
            917-3101            JAXUCZ010000017.1  6261961-6264145     c
FEATURES             Location/Qualifiers
     source          1..3101
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..3101
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="RecQ mediated genome instability 1"
                     /db_xref="GeneID:306734"
                     /db_xref="RGD:1310671"
     exon            1..235
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /inference="alignment:Splign:2.1.0"
     exon            236..831
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /inference="alignment:Splign:2.1.0"
     exon            832..916
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    898..900
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="upstream in-frame stop codon"
     exon            917..3101
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /inference="alignment:Splign:2.1.0"
     CDS             946..2799
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="RMI1, RecQ mediated genome instability 1, homolog"
                     /codon_start=1
                     /product="recQ-mediated genome instability protein 1"
                     /protein_id="NP_001387556.1"
                     /db_xref="GeneID:306734"
                     /db_xref="RGD:1310671"
                     /translation="

MSVASAVLRVETWLLATWNIKVPLMWLEACVNWIQEENNSANLSQAQINKQVLEQWLLTDLRDLEHPLLPDDILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKSTTNDLVSAETQTAPEPWQVRPSRMLMLQLTDGVTQVQGMEYQSIPALHSALPPGTKILVHGHILFRLGVLLLKAENVKVLGGEVDGLAEEYAQEKILARLIGEPDPTVSVIPNNSNPSAPRVSGDLDAALGPSDEELLASLDESEEPAASDDVTVGRLSFSTGPSSDTAPTIQTGFEPGCNISSRPKEKLPNQPVHFTDGEFDDFSLEEALLLEETVQKEKMEAKASQPLSLKESVGKRVEEAFSPRPGGLNHTASTHKQGNSHFSEKTSEQMIHEDTLFDCSSTRHHRKRLLAHDFTKDSKISEVDDVAQQTTNSSDVHCLSNKMLNRKPDLSEKSSQHSKGNGHPFQTCSSRSFENNTNLSIGMDLHCPPFIYLSVLMARKPKEVTTVKVKAFIVTLTGNLSSSGGFWCVTAKVSDGTAYLDVDFIDEILTSMIGYSVPEMKQLKKDPLKYKKFLEGLQKCQRDLIDLCCLMTVSYDPSSCKGMVLELQDVGVEHLENLKKRLNK"

     misc_feature    985..1557
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="RecQ mediated genome instability protein; Region:
                     RMI1_N; pfam08585"
                     /db_xref="CDD:462527"
     misc_feature    2386..2778
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="Recq-mediated genome instability protein 1,
                     C-terminal OB-fold; Region: RMI1_C; pfam16099"
                     /db_xref="CDD:465021"
ORIGIN      

gctgctcacgtgtgcggggaaagggggcggccgcgggggattttcgagccccgagggagttgggcgggggctggaggaggaggagggacgcccgagcgcggcggattgggcgggaagaagtgaaaagagaggggaagagaaaaccctaggaacaggaaagggagagcaccgggcggcgcgcggccccgggatcacgctactgccgctgtcgtgcgaggcgaggcggcaaggccagggcttctctgtgtatccctggctggagctccctctgtagacccaggctgtcctcaatctcagcttcgattgcctctgcctccgagtactgggataaagaagtgtgttgctgctggccagtccggcttcatgatcacttacgtcagtgctaatacatcactttttacctctgactttctttttggattaccttccaagaatcctgaagttatcttggtgtctttaacaagtcaaaaataggtgtttttttcttttttttaacatattggatgtgtgactgtgcacacatggctatacaagcaagtgggagccacagccagccttgtggagttggttctctcctctacccattggaccataggagtggactcatttattacgtttggtggcaggacctttaccctaagccatcttcctggcccaacttaatttttagaagaaaatagaaacataaaatgaatataaatatttgttactgatttaagatctcacctattgattgaacatcacatacaatatctagggatagtattctattaaaaaatttgaatctgattgaaaactaatcatggagtcaagtatgcctaaaccttagtgagtcatttctctgcagaagaggctttgagtactgaccatccagcgtgaaatccggtcattagatcttaggctgtcctgctaagtggtggatgtggatgctcctatttaaaagaaatgagtgtagctagtgctgtattaagagtcgaaacctggcttttggcaacatggaatattaaagtgcctctgatgtggctggaagcttgtgttaactggatccaagaagaaaataatagtgctaacttgagtcaggcacaaataaataagcaagtgttagagcaatggcttcttactgacctgagagacctggaacatcctctcttacctgatgacattttagaaattccaaagggagaactgaatgggttttatgctctacagatcaattccttggttgacgtaagtcagcctgcgtattcccagatacaaaagctgagaggaaagagtacaaccaatgatctagtgtcagcggaaacgcagacggccccagagccatggcaagtaaggccttctcggatgctgatgctgcagctcactgacggtgtcacacaagtccaggggatggaataccagtctattcccgctctccacagtgctcttcctccaggtacaaagatcctagttcatgggcacattttgttccgccttggtgttctcttactgaaggcagaaaacgtgaaggtgctaggaggggaggtagatggtcttgcagaagaatatgcccaagagaaaatacttgcaagattaattggagaacctgaccctacagtttcagtcattccaaataattctaatcccagcgcgcccagagtttcaggggatttagatgctgctttggggccttcagacgaagaactcttggcaagccttgatgaaagtgaagagcctgcagcaagtgatgatgtgacggtggggagactcagcttcagcacaggcccttcctcagatactgccccaacaattcagactggttttgagccgggatgtaatatttcttcaaggccaaaggagaaactaccaaaccagcctgtgcatttcactgatggagaatttgatgacttttccctggaagaggccttgcttttggaagaaacggtccagaaagagaaaatggaagcaaaagcatcacagccactgagtttgaaggagagcgtgggtaaacgtgtggaggaggccttctcacctagacctgggggtctgaaccacacagcctcgactcataaacaaggaaacagccacttcagtgagaaaacatctgaacagatgatccatgaagacacactttttgactgttcatctactagacaccatcgtaagagactcttagctcatgattttacaaaagacagtaagatttcagaagtagatgatgtagcacaacaaaccaccaacagttcagatgtacattgcttaagtaataaaatgttaaacaggaagccggacctatcagagaagagttcacaacattctaaaggaaatggccaccctttccagacttgttcttcaagatcatttgagaataatactaacctatctattggcatggacttacactgtccaccctttatctatttgtctgttctaatggccagaaagccaaaggaagttaccactgtgaaagtcaaagcatttattgtcactttaactggaaatctctcaagttccggtggcttttggtgtgtgactgcaaaggtttctgatggtactgcatatctagatgtagattttatagatgaaatacttaccagtatgatagggtattcagtaccagaaatgaaacagttaaaaaaggaccctcttaaatataaaaaattcctagaagggttacaaaaatgccagcgagatctgatagatttgtgttgcctaatgactgtttcatatgatccgtcttcgtgtaaaggcatggtactggaattgcaagatgttggtgtggaacacctcgagaacctaaagaagcggttgaataaataattgccagaatactattggagcacacttttaaaacaggcaaatatttggaatcaaatttgtttgttctcaattttggaattctgtaaaagaaaaagcttcagagcttaaaaatggctgaggcagctcagtggtggtttctgccaggtgtggtgacctgagtttgatctcctggtcccttgaggcaaaaggagagacccagcttcagcttccagaatctgttgttagtcctctacacaggtagcataggacacacacagttggtaaatgatgtttaaaaataaagatatttaatcaaaaatgta

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