LOCUS       XM_039097015            7573 bp    mRNA    linear   ROD 22-FEB-2024
DEFINITION  PREDICTED: Rattus norvegicus ST8 alpha-N-acetyl-neuraminide
            alpha-2,8-sialyltransferase 5 (St8sia5), transcript variant X6,
            mRNA.
ACCESSION   XM_039097015
VERSION     XM_039097015.2
DBLINK      BioProject: PRJNA1074393
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086036) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Feb 22, 2024 this sequence version replaced XM_039097015.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7573
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     gene            1..7573
                     /gene="St8sia5"
                     /gene_synonym="SATV; SIAT8-E; SIAT8E; ST8SiaV"
                     /note="ST8 alpha-N-acetyl-neuraminide
                     alpha-2,8-sialyltransferase 5; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 4
                     ESTs, 3 long SRA reads"
                     /db_xref="GeneID:364901"
                     /db_xref="RGD:1302934"
     CDS             6166..7077
                     /gene="St8sia5"
                     /gene_synonym="SATV; SIAT8-E; SIAT8E; ST8SiaV"
                     /codon_start=1
                     /product="alpha-2,8-sialyltransferase 8E isoform X5"
                     /protein_id="XP_038952943.1"
                     /db_xref="GeneID:364901"
                     /db_xref="RGD:1302934"
                     /translation="

MVKQSELFERWKSLQICKWAMDASEASLFNRSTLSRCCNAPNFLFTTQKNTPVETNLRYEVESSGLYHIDQEIFKMFPKEMPYYRSQFKKCAVVGNGGILKNSGCGKEINSADFVFRCNLPPISGIYTTDVGEKTDVVTVNPSIIIDRFHKLEKWRRPFFSVLQRYENASVLLPAFYNVRNTLVSFRVKYMLDDFQSRQPVYFFHPQYLSSVSRYWLSLGVRARRISTGLILVTAALELCEEVHLFGFWAFPMNPSGFFITHHYYDNVKPKPGFHAMPSEIFTFLRMHSRGILRVHTGTCNCC"

     misc_feature    6235..7056
                     /gene="St8sia5"
                     /gene_synonym="SATV; SIAT8-E; SIAT8E; ST8SiaV"
                     /note="glycosyltransferase family 29; Region: GT29;
                     cl45931"
                     /db_xref="CDD:480271"
     misc_feature    order(6448..6456,6517..6522,6586..6588,6844..6852,
                     6904..6909,6946..6954,6988..6990)
                     /gene="St8sia5"
                     /gene_synonym="SATV; SIAT8-E; SIAT8E; ST8SiaV"
                     /note="active site"
                     /db_xref="CDD:467690"
     polyA_site      7573
                     /gene="St8sia5"
                     /gene_synonym="SATV; SIAT8-E; SIAT8E; ST8SiaV"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

gcaattacgatctcacagcacagctgaagggactgagtcacctccaggtggtatgcagtagagagacagcacgccagggtaatgttgactctgaggtcccagctctggtgggagacgtgagagggattcttcacctgggctgtgggctggtcacccatgatgatgagcgctgtttaaatgtccacccatacatctctccccgcccttgactgttggaccaaacctgggtttaagaagactgcttctctgcagatttcccaaggaagatacatatagagaggtggcctattttaaccctaatatgggaaaactcacttactttaggctcacttactctctcccctacctctcccacttttttctgaaggtgggtgcagtgaactttattgatggtattgaaagagtagggctccctgggcccctcctgttattctgggggtctgggatggtaactgtgagggagatgctcagtgttgagggatgagttgggattgggattcctcagtgccctacagcctttctcttgttctcatgtcctcgctggggtgggtggtccagggattcttactccttggaggccacgtaggccgtgaggtccaccactctgctgctgtagccgtattcattgtcataccaggaaatgagctttacaaaggtgtcattgagagcaatgccagtcccagcatcgaaggtggaagagtgggagctgctgttgaagttgcaggagacaacctgatcctcagtgtaactcaagatgccctttagtgggccctcagatgtctgcttcgctatcttcttgatgtcttcatacttggcagccttcttcaggtgacagatccattccatgacagatatactgagggtaggaacatggaagaccatgtcaaatgagcttcccattcacctctgggatgaccttgcccatagccttggcagcaccagtggatacatggatgatgttctgggctactccatggccatcacaccacagttttccagaggggtcgtccacagtcttctgagtggcagtgatggcatggactatgatcttgggcccttccatgatggcaaagttgtcatggatgacctcggccaggggggcagttggtggtacagggagcactgtgacagtcttgagtgagttgtcatacatttcgtggttcacatccatcgcaagcactggggcatcatgggcagaatgggcagagatgctaacctttttggccccacccttcaagtggctccaagatagtgaagatactggtagactccatgcatactcggcaccagcaccaccccatttgatgttagcaggatgtcactcctggaagatgggtttggccttcccaatgacggcattctcagccttgactgtgctgttgaacttgccatgggtagagccacactggagcatgtagaccaggtaggccatgtagttgaggtcagtgatgcagtcagattcactttgccaggtaagaaggcagcccttctaatcagttgcctgatatggccaaatcctttcaccccgacctttaccatgtgtctaagggccaaggctggcactgcacaagaagacgtggctgtctctgaaacaggaaggagcagagagcctctttcccacttctgttctctcttcactcttcaggagggggatttttttttcctgatcccttgacctctgaggttaatattttccctgtctcagcctgcacctgggggttcacaatttcagaacaatcccgtttccaaggtggaacttgaggtgtaacagtgggcttgaacacttcccaatagcctggcccgcatgaccacccttccattctgcctcctgtaagagtgcctccccctcagggtagtttgagatgcgggctggctcagcgtgaacctttcagatgaattttcacttctttggaaaaataaagtgggcacaaaagagagacagatctcttgggttgcatccaaatgagaggaatttggagagtcggctttggcagaatcgctcctggctgggtgctggggaaacacagcaaagcaaatatggtgtcttcccccattcatcccacgtacctgatgtaggcctcccacggcccgacagtatcaggcttcaagcagatgaggttggtggtggaagtggaggctatgccaggaggctcttaagatagtgttgctttatgggcttccaacctctgagatttggggatcataatgagtctcagcacagtctcctctcttatggggcatctacactcacgagttcactctcagaaagtttccttccctctgattctgctcctgctcctgtaagttggcattaattcaactgttcagcagacagaaaggaggtcagtcacgcagttggagcatgccaaggaccccaaggttaaaataccccacacaggtaagctcctcacagcctcacgaaggtgttactgaggccccctgaagagacattcccaacagggccagatgccagctttgcccctgattcagggcattgtcttggagaggcagcactgcatgtttgggccatgtctccttaaaactgaagggaagccctagtgaactttctagcttcactgttttgattgacttttttctttttaaatcactacttttggaggtcacagagccaagcaatgcattcccagtctcccactggctttgctgatgcccctgagtgtgagtcttgtcagtactggttgtctaagttacttctcagggactctaagactgcttttgtcaaagctacaggctcactactaaagcccacataggtacccagtgactgatctcttggtgtcagagggccaaacccacccactatttcttaagccttcctcccataaggggccacgaggctggatcacacacaggcagatcatggctcatttcacccagtcacctctccctgcacctcaggccactcctccccataaccaccgtgtgaacatactctccattacaaaactcacagtttcagtggttatcctattctgcagcaggagaaacagggctggctcagtaaccacccctctgctgaagcagcttccaccatagcagccagctcccaggcaccctgacctgtcccctctcacacccctaccctctcaccttcctcgtggttccgcccttcttgcctgctccactgtctctgagcacttcacaccaggacttggcaaaggtgggaggacggagagaggtggagaacggaaggaaaaggaggtgggggctgggccaggaagccagtgtatcaatttgatatttgataatccaatcaggggtacttctagtgcccacctccccacccccacctccaaattaaaggctatagattctcctagaagctccacacactctcctagtttggtgggcaccaagactgtcactggagagtaagtgatggaggctcacaaagatggcaggaggccaccctccatcgagggctgtcctgtgagaagtccttcctcatactaagtgtgaccctttttcctgtgctcactaggagcttctacttgctttttattgcttcacagagcactaacatccatccgtcctctctgcagctgtccctgatgtgttggaaagcatcaatacttccccttcttcctggccctggaacccagtctccaacattccctcccctagctctactattcctcaagacttcagccattacccaccccaccccagtcttacattaacacatgcccacgaagcgttatctgctattgtcaaggtcactgtgacctctaagtggtcatatcagtgccaccttcccttcttccttgaccccactggcactgggtggagctgtcccttgtgtcctgaaaaggcccttggtccctgggctccacatcctggtttgtcctcgttcctgcataccgttcttctcagtctaacctcaggcctgtctttccccctccccacctctaagagctcatggggtgtctctgtccatcgactctggatcgtgtgttttgtcctgtgcatcccatttgtacctgactcttacctgctgcctctcaccctctgatggctgagggtcacagagaacactccttggccattctccttaccattcatacccaagtcattgggtggctccatcacaccactccgtagactttgttcatccaaatactgaatcttagcactcccctcagggtccatctctgcactactgctcaggtttctctcccctaccccttgctttcaacctcttggtgccatgcgccatctccttacactgctgagtttcttctcctctcggaacccccttctcagccagtgtgaacttttaaatcaaattatgttgtcccctgcctaaatgcttttcaaactcctgacccatgacccagcccttctgatgctaccaccctgttccagtcatcctggctgccgtcataccgcagctggctagctcttgctgtataaactggtcgcacatctgcccagggctgcatccctccctctgctcactgtctggagacaccttcactaacctggtcgtctcagagtccctctagtttcctacctgcattgcttctgcagcactcattctgctatgttgagaagcacctcgagggaggagccttggcctggctagttgatcactactaaggtagaaatagcctgacacgcaagggaggctcaacaagcattcagtgaggaagagataagccttcctgacccctgaggggtacaggcaggccacgaggaatcatgtttaagtcatttctaggggaggtggagatgtgcccagtgggtgttggcacagagaggggagggcaggaaggtggcctggagatgctgaccaggtagatctctgaatgaagtaagtaggaaaacatctcagagccagagtcagacaccagggaaacaggcagagcgaattacagcctgtgctggggcggagaccagggccactaccgaggcaaagatctggagggataaaggagaaggagatgacttgggtgcagctctgggcttagcacaaggagatggtgaccaaagcccagtagggtcagtgagacctccaaccaggggccatgttaagcagtcagagctaagctggacctcaggaatgctgtcagggtcccctggactggcttagaagaggttaccttacagggactgtgctggccgccaggtcaagggctgcagctggggaagggattatgggatggagtctctgaatttgttattgctccttacctacccagaccccaaccaaggggagcggtgacagtgcagactttgcaaagtggtgtggtagaacagactgaccatggggatatccagaactaattccagaacagcaaaatgtaagcttttatttatttagtttattcgtttattatttttgcagtgttagggtttaaatgtaggactttgcccatgctaagcaactactcaaccatccacctacactcacagcctgcttttaccttaattaaaaaaaaaataacattcaagatagatccttcctaagcgtccccagctggccttgaagtgactctagcccatgtaggccttgaacttgtggtcctcctgcttcagcctcccccagagctgggtttataagtctgtgccaccaggtccatgtcactaagcctgctgcctgttaatatttagaccttttagctctggtgactcctggcatagggaaaccacacctcagagagaacaggttaagtcaaagattgctgagcagacatggagggcccccggcaatgcctcctcccagcagtcacagcctttggcggctggtggtagggagccctgagtccctctgcacctatccgggggcacttacagccctggtacttgtcagtctgcagctctccgactgctttctgctgatggggcgtgtgctcgctccagacagcagctgttcttgtgctggaaatagcacggatctcgctgaagggctgtcgcctttgggagagaagggggctgcttattgacaaagcccccagggagccgtcgctgtcagagttggcgaggggcgactgctgaagtgatggagaccctggggttctgggcgcttggaagcctgagctttcctctctgtcgtacttcgaattttacaaggaacctttagaatttaactccacgagatgcctggagctgaggcaggagatcctggaggtgaaggtgctgtccatggtgaagcagtctgaactgttcgaaaggtggaagagcctccagatatgcaaatgggcgatggacgcctcggaagccagcctcttcaacaggtccaccttgtccaggtgttgcaatgcccccaactttctcttcaccacccagaagaacaccccggttgagacgaatctcaggtatgaggtggagtccagtggcttgtatcacatcgaccaagagatcttcaaaatgtttcccaaggaaatgccctactaccgctctcagtttaagaagtgtgctgtggtgggcaatggcggcatcttgaagaacagcggctgcgggaaggagatcaacagcgctgacttcgtcttccggtgcaatctgccccctatctcagggatatataccacagatgtgggagagaagacagatgtggtcaccgtgaatcccagcatcataattgacaggttccacaagttggagaagtggcggcggcccttcttcagcgtgctgcagaggtacgagaacgcctcggtgctgctgccggccttctacaatgtgcgcaacaccctcgtgtccttccgagtcaagtacatgctggacgacttccagtcgcggcagcccgtctacttcttccatcctcagtacctgagcagcgtgtcgcgctactggctcagcctgggcgtgcgcgcacggcgcatcagcaccggcctcatcctggtcactgcggccctggagctctgcgaggaggtgcacctgttcggtttctgggccttccccatgaacccctccggcttcttcatcacgcaccactactatgacaatgtcaagcccaagcccggctttcatgctatgccctcggagatcttcaccttcctgcgcatgcacagccgcggcatcctccgcgtgcacacaggcacctgcaattgctgctgaaaaacaggcccaccacgggtgtttcagctcctgtcctcctccccgaaggatcccctgtccctgccattatggctgttgtcactccctaaggatttagggtttgtgtttgggtcctggggagggaggcagggagacattcatttaacaggatagagcacagatccaggtctcattcagacctttggctgcccgagtttcatacggggaactcagccataaagcaccatcttgaaactcacggcctgggtgccagcccttccagggaacaaacagtatgagtgtcctagtcacaccacctggctgagctcaaaagacttcagggatatctaatcaaaacccgtgttagcatatccccacgagtccaggagctgagagccatgccctttaaaacagctcttggacacacacagccttggtgcctctaggttccagcctgcatttaacctttgacaagaaggaaataaaccagaccagccatttgcactaagatcttcaa

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