LOCUS       NM_001399756            2179 bp    mRNA    linear   ROD 28-APR-2025
DEFINITION  Rattus norvegicus homeobox D8 (Hoxd8), transcript variant 2, mRNA.
ACCESSION   NM_001399756 XM_039106383
VERSION     NM_001399756.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2179)
  AUTHORS   van den Akker,E., Fromental-Ramain,C., de Graaff,W., Le
            Mouellic,H., Brulet,P., Chambon,P. and Deschamps,J.
  TITLE     Axial skeletal patterning in mice lacking all paralogous group 8
            Hox genes
  JOURNAL   Development 128 (10), 1911-1921 (2001)
   PUBMED   11311170
REFERENCE   2  (bases 1 to 2179)
  AUTHORS   Zappavigna,V., Renucci,A., Izpisua-Belmonte,J.C., Urier,G.,
            Peschle,C. and Duboule,D.
  TITLE     HOX4 genes encode transcription factors with potential auto- and
            cross-regulatory capacities
  JOURNAL   EMBO J 10 (13), 4177-4187 (1991)
   PUBMED   1756725
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jan 13, 2022 this sequence version replaced XM_039106383.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.17199.1,
                                           SRR26643290.11916.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-786               JAXUCZ010000003.1  80015223-80016008
            787-2179            JAXUCZ010000003.1  80016397-80017789
FEATURES             Location/Qualifiers
     source          1..2179
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q23"
     gene            1..2179
                     /gene="Hoxd8"
                     /note="homeobox D8"
                     /db_xref="GeneID:100912936"
                     /db_xref="RGD:6489440"
     exon            1..786
                     /gene="Hoxd8"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..1079
                     /gene="Hoxd8"
                     /note="isoform 2 is encoded by transcript variant 2;
                     homeobox protein Hox-D8-like"
                     /codon_start=1
                     /product="homeobox protein Hox-D8 isoform 2"
                     /protein_id="NP_001386685.1"
                     /db_xref="GeneID:100912936"
                     /db_xref="RGD:6489440"
                     /translation="

MSSYFVNPLYSKYKAAAAAAAAAAAAAAAGEAINPTYYDCHFAPEVSGRHAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPGCGGGGGPGPGQNYFHAGAGSPVAAYQAAPPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHTLALTERQVKIWFQNRRMKWKKENNRDKFPASRPEAKDGDPKKEVSGLEEDGAEGPTN"

     misc_feature    630..1028
                     /gene="Hoxd8"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]; Region: COG5576"
                     /db_xref="CDD:227863"
     misc_feature    798..968
                     /gene="Hoxd8"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            787..2179
                     /gene="Hoxd8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gacacggaggcgcgagagccgggcatgagcggccggcggccggacggtcgggcctgagggggaaagcgcgcgccgggcgacgaggcccggcggcccccgcggctcgagcgagccgccccagaggcccccgcggcagcgcggccgagctgaggcgcgctcctcaccggctccgtgccgcccgtccgcccgcggccgccgccccgatgagctcctacttcgtgaacccgctgtactccaagtacaaggcggcggccgcggcggcggcggcggcggcggcggcggccgcggcgggcgaggccatcaatcccacttactacgactgtcatttcgcgcccgaggtcagcggccgccacgccgccgccctgcagctctatggcaacagcgccgccggcttcccgcacgcgcccccgcaggcgcacgcgcacccgcacccgtcgccgccgcccgggtgcggcggagggggcggcccgggccccggccagaactacttccacgccggcgcgggcagcccagtcgctgcctaccaggccgccccacctcctcctccgcaccctccgcctccaccgccgcctcccccctgcggcgggattgcctgtcacggggagcccgcgaagttttacggatacgataacttacagagacagccgatttttacgacccagcaagaggccgagctggtacaatatcctgactgtaaatcgtccagtggtaatattggcgaggacccagaccacttaaatcagagctcgtctccttctcaaatgtttccctggatgagaccacaagctcctggtagacggagaggaagacaaacctacagtcgcttccaaaccttagagttggaaaaggaattcctttttaacccttatctgaccaggaagagaagaatcgaggtctcccatactctggccctcacggagagacaggtaaaaatctggttccagaacaggagaatgaagtggaaaaaagagaacaacagagacaagtttccagcgtcccggccggaggcaaaggatggagaccccaaaaaggaagtctcagggctggaggaagacggagccgaaggccccacaaactaaacctttacatttcatcatagactgttaagactagtgatcagtataagtatatactggtggacgccaccgtttctcccctcttcctttttggaaaggactttacctgtgtttcaagctaccttaatgtcgctgctcttgaggtttctgcgctttgaaggggacttgggtgttttcaaagaaagtagttttgtagtgtcgcatagaggcagtccttgagctggtccgtagagggtaatttgatactgaccttgtagctatatttttataatggtagtttttaacgtctgagctggtgatttgcctcaacaacataaacttcctaatgatcagcactagatgattgaatataaaatgctttattaatcaaacaagtgcacttgaacattttaaatctttatggtgagtaaattaaaagaagtttattaataatgtttttaaaattatgcctgcaaaatatttactttattatttgattaaatgtattatttatatttttctttctgcttttgtaacaatggtttgcgtgtcttctggtttacttccagaaggttcctttgagcattttgtaaatgttgtcagggaagagtctgggccaaatattggaaaagcacattagctgaagagtgcaatgtactgtccaggctgccggcttccttaaacctgggagtgttgtgccagtgagtttaaggatgatgtcaaatttagtcctgtgtctgtagtttgtacaaattaaggccatcaaataatctagagaattaatacttgaaatcttattgcaacattttcactaactgttcgtcctggcaagtggccttgctttcattttgaagcccgcttgtgatcacctgggatttctaggtctttgctctatgctgctttttcaagtaggtgccatatttattgtattctccttgcactgctcctatgcttgctgtgttcatctcagatgtcggttggtacgtccatcctctgctgttcttcaggaaagccatggcctcgcccatttgaaatgagccctgagtgtaaatgcagaaactccgagtgtaaacaaccgctccagagcatagctccttaataaagagatgtacctccataaagag

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