LOCUS       NM_001399755            2182 bp    mRNA    linear   ROD 28-APR-2025
DEFINITION  Rattus norvegicus homeobox D8 (Hoxd8), transcript variant 1, mRNA.
ACCESSION   NM_001399755 XM_039106382
VERSION     NM_001399755.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2182)
  AUTHORS   van den Akker,E., Fromental-Ramain,C., de Graaff,W., Le
            Mouellic,H., Brulet,P., Chambon,P. and Deschamps,J.
  TITLE     Axial skeletal patterning in mice lacking all paralogous group 8
            Hox genes
  JOURNAL   Development 128 (10), 1911-1921 (2001)
   PUBMED   11311170
REFERENCE   2  (bases 1 to 2182)
  AUTHORS   Zappavigna,V., Renucci,A., Izpisua-Belmonte,J.C., Urier,G.,
            Peschle,C. and Duboule,D.
  TITLE     HOX4 genes encode transcription factors with potential auto- and
            cross-regulatory capacities
  JOURNAL   EMBO J 10 (13), 4177-4187 (1991)
   PUBMED   1756725
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jan 13, 2022 this sequence version replaced XM_039106382.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.11964.1,
                                           SRR26643285.11936.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-786               JAXUCZ010000003.1  80015223-80016008
            787-2182            JAXUCZ010000003.1  80016394-80017789
FEATURES             Location/Qualifiers
     source          1..2182
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q23"
     gene            1..2182
                     /gene="Hoxd8"
                     /note="homeobox D8"
                     /db_xref="GeneID:100912936"
                     /db_xref="RGD:6489440"
     exon            1..786
                     /gene="Hoxd8"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..1082
                     /gene="Hoxd8"
                     /note="isoform 1 is encoded by transcript variant 1;
                     homeobox protein Hox-D8-like"
                     /codon_start=1
                     /product="homeobox protein Hox-D8 isoform 1"
                     /protein_id="NP_001386684.1"
                     /db_xref="GeneID:100912936"
                     /db_xref="RGD:6489440"
                     /translation="

MSSYFVNPLYSKYKAAAAAAAAAAAAAAAGEAINPTYYDCHFAPEVSGRHAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPGCGGGGGPGPGQNYFHAGAGSPVAAYQAAPPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHTLALTERQVKIWFQNRRMKWKKENNRDKFPASRPEAKDGDPKKEVSGLEEDGAEGPTN"

     misc_feature    630..1031
                     /gene="Hoxd8"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]; Region: COG5576"
                     /db_xref="CDD:227863"
     misc_feature    801..971
                     /gene="Hoxd8"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            787..2182
                     /gene="Hoxd8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gacacggaggcgcgagagccgggcatgagcggccggcggccggacggtcgggcctgagggggaaagcgcgcgccgggcgacgaggcccggcggcccccgcggctcgagcgagccgccccagaggcccccgcggcagcgcggccgagctgaggcgcgctcctcaccggctccgtgccgcccgtccgcccgcggccgccgccccgatgagctcctacttcgtgaacccgctgtactccaagtacaaggcggcggccgcggcggcggcggcggcggcggcggcggccgcggcgggcgaggccatcaatcccacttactacgactgtcatttcgcgcccgaggtcagcggccgccacgccgccgccctgcagctctatggcaacagcgccgccggcttcccgcacgcgcccccgcaggcgcacgcgcacccgcacccgtcgccgccgcccgggtgcggcggagggggcggcccgggccccggccagaactacttccacgccggcgcgggcagcccagtcgctgcctaccaggccgccccacctcctcctccgcaccctccgcctccaccgccgcctcccccctgcggcgggattgcctgtcacggggagcccgcgaagttttacggatacgataacttacagagacagccgatttttacgacccagcaagaggccgagctggtacaatatcctgactgtaaatcgtccagtggtaatattggcgaggacccagaccacttaaatcagagctcgtctccttctcaaatgtttccctggatgagaccacaagcagctcctggtagacggagaggaagacaaacctacagtcgcttccaaaccttagagttggaaaaggaattcctttttaacccttatctgaccaggaagagaagaatcgaggtctcccatactctggccctcacggagagacaggtaaaaatctggttccagaacaggagaatgaagtggaaaaaagagaacaacagagacaagtttccagcgtcccggccggaggcaaaggatggagaccccaaaaaggaagtctcagggctggaggaagacggagccgaaggccccacaaactaaacctttacatttcatcatagactgttaagactagtgatcagtataagtatatactggtggacgccaccgtttctcccctcttcctttttggaaaggactttacctgtgtttcaagctaccttaatgtcgctgctcttgaggtttctgcgctttgaaggggacttgggtgttttcaaagaaagtagttttgtagtgtcgcatagaggcagtccttgagctggtccgtagagggtaatttgatactgaccttgtagctatatttttataatggtagtttttaacgtctgagctggtgatttgcctcaacaacataaacttcctaatgatcagcactagatgattgaatataaaatgctttattaatcaaacaagtgcacttgaacattttaaatctttatggtgagtaaattaaaagaagtttattaataatgtttttaaaattatgcctgcaaaatatttactttattatttgattaaatgtattatttatatttttctttctgcttttgtaacaatggtttgcgtgtcttctggtttacttccagaaggttcctttgagcattttgtaaatgttgtcagggaagagtctgggccaaatattggaaaagcacattagctgaagagtgcaatgtactgtccaggctgccggcttccttaaacctgggagtgttgtgccagtgagtttaaggatgatgtcaaatttagtcctgtgtctgtagtttgtacaaattaaggccatcaaataatctagagaattaatacttgaaatcttattgcaacattttcactaactgttcgtcctggcaagtggccttgctttcattttgaagcccgcttgtgatcacctgggatttctaggtctttgctctatgctgctttttcaagtaggtgccatatttattgtattctccttgcactgctcctatgcttgctgtgttcatctcagatgtcggttggtacgtccatcctctgctgttcttcaggaaagccatggcctcgcccatttgaaatgagccctgagtgtaaatgcagaaactccgagtgtaaacaaccgctccagagcatagctccttaataaagagatgtacctccataaagag

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