LOCUS       NM_153573               2707 bp    mRNA    linear   ROD 12-SEP-2023
DEFINITION  Mus musculus FK506 binding protein 14 (Fkbp14), transcript variant
            1, mRNA.
ACCESSION   NM_153573
VERSION     NM_153573.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2707)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2707)
  AUTHORS   Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa
            K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito
            R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T,
            Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe
            M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held
            WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA,
            Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts
            P, Muramatsu M, Okazaki Y, Kawai J and Hayashizaki Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY775871.1, AK081692.1 and BC024846.1.
            
            On Jun 3, 2018 this sequence version replaced NM_153573.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC029109.1, AK030620.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                BY775871.1         2-21
            21-1369             AK081692.1         2-1350
            1370-2707           BC024846.1         1751-3088
FEATURES             Location/Qualifiers
     source          1..2707
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 27.01 cM"
     gene            1..2707
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /note="FK506 binding protein 14"
                     /db_xref="GeneID:231997"
                     /db_xref="MGI:MGI:2387639"
     exon            1..328
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    99..101
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /note="upstream in-frame stop codon"
     CDS             132..767
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /EC_number="5.2.1.8"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; peptidyl-prolyl cis-trans isomerase FKBP14;
                     rotamase; PPIase FKBP14"
                     /codon_start=1
                     /product="peptidyl-prolyl cis-trans isomerase FKBP14
                     isoform 1 precursor"
                     /protein_id="NP_705801.1"
                     /db_xref="CCDS:CCDS20157.1"
                     /db_xref="GeneID:231997"
                     /db_xref="MGI:MGI:2387639"
                     /translation="

MRFFLWNAILALWVTVLSGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPVWFTLGILEVLKGWDQGLKGMCVGEKRKLTVPPALGYGKEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWRLSKHEVKVYLQKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISAREFTYVHDEL"

     sig_peptide     132..188
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     mat_peptide     189..764
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /product="Peptidyl-prolyl cis-trans isomerase FKBP14.
                     /id=PRO_0000025522"
                     /note="propagated from UniProtKB/Swiss-Prot (P59024.1)"
     misc_feature    243..527
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase;
                     Region: FKBP_C; pfam00254"
                     /db_xref="CDD:425560"
     misc_feature    552..743
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /note="EF-hand domain pair; Region: EF-hand_7; pfam13499"
                     /db_xref="CDD:433258"
     misc_feature    657..659
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (P59024.1); glycosylation site"
     misc_feature    753..764
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /note="propagated from UniProtKB/Swiss-Prot (P59024.1);
                     Region: Prevents secretion from ER.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU10138"
     exon            329..480
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /inference="alignment:Splign:2.1.0"
     exon            481..608
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /inference="alignment:Splign:2.1.0"
     exon            609..2690
                     /gene="Fkbp14"
                     /gene_synonym="FKBP-14; FKBP22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agaaaaagtgccacgtcttcctgggagtgtgtctgttgggggagtcctgaacttgcttggcctaagctgtctccgcttttggcacatttttaactctatgaagtcgggggcctttcctctgctttggtaacatgaggtttttcttgtggaacgctatcttggcactgtgggtcacggttctgagcggagctctgattcctgagccagaagtgaaaatcgaagttctccagaagccattcatctgccatcgcaagaccaagggaggggatctgatgttggtccactacgaaggctatttagaaaaggacggctccctgtttcattccactcacaaacataacaatggtcagcctgtctggttcaccctgggcatactggaggttctcaaaggctgggaccaaggcttgaagggaatgtgtgtgggagagaagcgaaagctcaccgttcctcctgccctgggctatggcaaagaaggaaaaggtaaaatccctccagagagcacactgatattcaacattgacctcctggaaattcgaaatggcccaaggtcccacgagtcgtttcaagaaatggacctcaatgacgactggagactctctaagcatgaggttaaagtgtatttacagaaggagtttgagaagcacggtgccgtggtgaatgaaagccatcacgatgctttggtggaagatatttttgataaagaagatgaagacaaagatggatttatatctgccagagaatttacatatgtgcacgacgaactgtagggacgcgcctgccattttatacacgttcatttctaatggaaaggcagcacctttgaacaaagcttttctctttgcctttcttgtttttagttttatattctttttctattatttaaagaacctcagagactttgtaaatatcgttcgtatctttccagtgagttattgggcaggaacggttgtctttgagtagaggactcccaggccgcttctaagctcacatgggagttggctttgcttccttgcttctttctaatggtaacatggcaactggaaacacaccccagcatacacacagggtgtagcacagaccagggccctgtacttctccctccctctgtcttctcaaagtccagttactggcatatttgaaagcttttgtgctagttcaaggcttgctattttcatgttatagtgaagtgattttttctttacctgcttttgagtccctgcttgcaggcaggaggaatatggtggaccttattccttaagagctctggccttactgtggagatacacaatgtggatgaatgagggaggtagcaactcatgaataggtggtcagagacgtcctagtggctaataaaccattacaataagtcagacaaataatatatttgtttccttgtaatcaacacaccaaaatatggtaggcatggcagagagttgtatttataattaatgtttacttttggagctaccaagttagccttctggttcttaaataaataaagtttgcagctagtatattactttgcaacagcattgaatcctgggagaaattagtatgtcaatgagacttccccatttctgattcatgaaaaataaggctaaccaataacagctactattaatactgggcactgacatttatcattttatctcaaattggcttccaaaaatgactactacttctgttttttagattgtttttaatcaaattggcttttatcttaaaacaaacttcccagacctccatttgttatgctcctcatagtttacacgtgcacaattgcctgactgggggtgtctgacacccctgggaagctgctgggtcttggggtacttctttataggtgagaagctctgttcagagattggctggtgagcccagccttggtgcctaagctgtagatgcaccttcagtccctgagttcagtcttccacttctctgctaatgaagatgcagcaagtttgcgtctctctctcttggtccttatttcccttagcatcttcacctctggggataattcctgccagttcctagctgatcacagctttccttaggatccaggaaggtctgtgttttctgagaatagtcttgctttgtgtgtctctctcccagtaaccccctgagaggggttaggtgtatgtcttatggcatctaagttcacctgttcctgtcacttcctgttgtttgtagacattgtattgcaacacgaattctgcattgacattgttactggcgagaattactcaagggcttgttcttgaagatgtcaggggtaactgtaactgttgccacctgcatttttctggggaggttgtgagaaagccagtgagtgtcgtagaccagtggtgtgtcttgaaggctgctttgctccaagctgccaccaccatctgcgctggagcagtgaagaagaaagaatcttgaccactcaattacatggatttttatcagatctcagctaaactttcaaacagaagtatgaaagaaagacatacctggagaaaatggttgttaaagccatctgccattgtgtatagcaatgcctttgcaccctcccattagtgggaatagtcaaacaccaaatgtgacttcacatgtatatactttgactcctagctgctctctgtgtaatatttaaatttctatgtctattgtgacactctttttgaaaataaagtttatttgggaaataaaaaaaaaaaaaaaaaaa

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