LOCUS       NM_001411492            1397 bp    mRNA    linear   ROD 08-AUG-2023
DEFINITION  Mus musculus alcohol dehydrogenase 6B (class V) (Adh6b), transcript
            variant 3, mRNA.
ACCESSION   NM_001411492
VERSION     NM_001411492.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1397)
  AUTHORS   Szalai G, Veres M, Duester G, Lawther R, Lockhart M and Felder MR.
  TITLE     Tissue expression pattern of class II and class V genes found in
            the Adh complex on mouse chromosome 3
  JOURNAL   Biochem Genet 46 (11-12), 685-695 (2008)
   PUBMED   18802746
  REMARK    GeneRIF: Adh6b gene expression patterns.
REFERENCE   2  (bases 1 to 1397)
  AUTHORS   Gonzalez-Duarte R and Albalat R.
  TITLE     Merging protein, gene and genomic data: the evolution of the
            MDR-ADH family
  JOURNAL   Heredity (Edinb) 95 (3), 184-197 (2005)
   PUBMED   16121213
  REMARK    Review article
REFERENCE   3  (bases 1 to 1397)
  AUTHORS   Szalai G, Duester G, Friedman R, Jia H, Lin S, Roe BA and Felder
            MR.
  TITLE     Organization of six functional mouse alcohol dehydrogenase genes on
            two overlapping bacterial artificial chromosomes
  JOURNAL   Eur J Biochem 269 (1), 224-232 (2002)
   PUBMED   11784316
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC079845.31.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784647.358166.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164140 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AC079845.31        58011-58036
            27-125              AC079845.31        58836-58934
            126-227             AC079845.31        60106-60207
            228-366             AC079845.31        65669-65807
            367-454             AC079845.31        68205-68292
            455-674             AC079845.31        68417-68636
            675-935             AC079845.31        68818-69078
            936-1071            AC079845.31        70039-70174
            1072-1210           AC079845.31        73684-73822
            1211-1397           AC079845.31        74711-74897
FEATURES             Location/Qualifiers
     source          1..1397
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 64.21 cM"
     gene            1..1397
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="alcohol dehydrogenase 6B (class V)"
                     /db_xref="GeneID:100417514"
                     /db_xref="MGI:MGI:2446626"
     exon            1..26
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            27..125
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    36..38
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="upstream in-frame stop codon"
     CDS             87..1241
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /EC_number="1.1.1.1"
                     /codon_start=1
                     /product="alcohol dehydrogenase 6B (class V)"
                     /protein_id="NP_001398421.1"
                     /db_xref="GeneID:100417514"
                     /db_xref="MGI:MGI:2446626"
                     /translation="

MEQASLATKTSSNVIRCRAAVAWTTNAPLSIEEVEVDPPKAGEVRVKIIASGICGTDNHTLEGKMKTPFPVILGHEGAGVVESVGPGVTTVKPGDKVLMFPLPECRECFYCLYPKGNFCEKENILSPTGLMLDGTSRFTCRGKKIYNIMGTSTFTEYTVVHEIAVAKIEAAAPMDTVCIMSCAVPTGFGAVFNTAQVTPGSSCVVFGLGGIGSAIVMACKASGACRIIGVDINEEKFPRARALGVTDCLNPNKLKKPVQEVVKEMTGVGVDFAFEAIGLIETMVAALKSCNRSYGVCVIMGVAPTGSQLSFDPLVLLPGRTLKSSVLGGYKTRDDIPKLVTDYVQKKINIDPLITHRLPFPKINEGFRLLQEGKCIRCVLSMRP"

     misc_feature    114..1232
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="Medium chain reductase/dehydrogenase
                     (MDR)/zinc-dependent alcohol dehydrogenase-like family;
                     Region: MDR; cl16912"
                     /db_xref="CDD:450120"
     misc_feature    order(246..254,261..263,630..632,642..644,705..722,
                     777..782,792..794,837..839,912..917,984..989,1059..1067)
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:176178"
     exon            126..227
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            228..366
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            367..454
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            455..674
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            675..935
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1071
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1210
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1397
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agtccgccctgcatttactctctgagtccagcaggtaaccgcttgagacagaagagccctccagtctaaaccttccagaagcaaagatggaacaagccagcctcgccacaaaaacatccagcaatgtcatcagatgccgggcagctgttgcctggaccactaatgccccgctgtccattgaggaggttgaagttgatccaccaaaggctggtgaggttcgagttaagattatagcctctgggatctgtggcactgataatcataccttagaagggaaaatgaaaacgccatttcctgtcatcctgggccacgagggagctggagttgtggagagtgttggaccaggtgtaaccactgtaaagccaggagataaagtcttaatgttccctcttccggaatgtcgagaatgcttctactgcctctaccctaagggcaacttctgtgagaaagaaaatattctctctccaactggattaatgttggatggaaccagcagatttacctgcagagggaagaaaatctataatataatggggaccagcacgttcacggaatatactgtggtgcatgagattgcagtggcgaagatcgaggctgctgcccctatggatacagtctgcatcatgagctgcgcggtgccgacaggctttggagctgtgtttaacacagctcaggtcacccctggctcttcctgtgtggtgtttggactcggaggaattggctctgccatcgtcatggcctgcaaagcctctggagcatgtagaatcatcggggttgacatcaatgaggagaaatttcctcgggcaagagccttgggggtcaccgactgtctcaaccctaacaagctgaagaagcctgtgcaggaggtggtgaaggaaatgacaggggttggtgttgactttgcctttgaggccatcggactcattgaaaccatggttgcggctttgaagtcatgcaataggagctacggagtgtgtgtgattatgggagtagctccgaccggttcccagctctcttttgacccattggtacttctccctggaagaaccctaaaatcttctgttttgggagggtataaaaccagagatgacatccctaaactagtaactgactacgttcaaaagaaaattaatatagatcctcttataacccatagactgcctttcccaaaaatcaatgaaggattcagattgttgcaagagggaaaatgcatccgttgtgtcctctctatgagaccctgatggtgaccggcacacgggcatctcagcagtgctcttctatgcttctttacctccttggagattaaactgcaaactatggagatcagaacaggaaacacacacacacaattttaacgaattaaactgttaaagaaaataaactatctcaaaactctt

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