LOCUS       NM_001411491            1462 bp    mRNA    linear   ROD 08-AUG-2023
DEFINITION  Mus musculus alcohol dehydrogenase 6B (class V) (Adh6b), transcript
            variant 2, mRNA.
ACCESSION   NM_001411491 XM_006502558
VERSION     NM_001411491.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1462)
  AUTHORS   Szalai G, Veres M, Duester G, Lawther R, Lockhart M and Felder MR.
  TITLE     Tissue expression pattern of class II and class V genes found in
            the Adh complex on mouse chromosome 3
  JOURNAL   Biochem Genet 46 (11-12), 685-695 (2008)
   PUBMED   18802746
  REMARK    GeneRIF: Adh6b gene expression patterns.
REFERENCE   2  (bases 1 to 1462)
  AUTHORS   Gonzalez-Duarte R and Albalat R.
  TITLE     Merging protein, gene and genomic data: the evolution of the
            MDR-ADH family
  JOURNAL   Heredity (Edinb) 95 (3), 184-197 (2005)
   PUBMED   16121213
  REMARK    Review article
REFERENCE   3  (bases 1 to 1462)
  AUTHORS   Szalai G, Duester G, Friedman R, Jia H, Lin S, Roe BA and Felder
            MR.
  TITLE     Organization of six functional mouse alcohol dehydrogenase genes on
            two overlapping bacterial artificial chromosomes
  JOURNAL   Eur J Biochem 269 (1), 224-232 (2002)
   PUBMED   11784316
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC079845.31.
            
            On Aug 26, 2022 this sequence version replaced XM_006502558.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189676.73367.1,
                                           SRR5189679.107113.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AC079845.31        58011-58036
            27-91               AC079845.31        58239-58303
            92-190              AC079845.31        58836-58934
            191-292             AC079845.31        60106-60207
            293-431             AC079845.31        65669-65807
            432-519             AC079845.31        68205-68292
            520-739             AC079845.31        68417-68636
            740-1000            AC079845.31        68818-69078
            1001-1136           AC079845.31        70039-70174
            1137-1275           AC079845.31        73684-73822
            1276-1462           AC079845.31        74711-74897
FEATURES             Location/Qualifiers
     source          1..1462
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 64.21 cM"
     gene            1..1462
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="alcohol dehydrogenase 6B (class V)"
                     /db_xref="GeneID:100417514"
                     /db_xref="MGI:MGI:2446626"
     exon            1..26
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            27..91
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            92..190
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    101..103
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="upstream in-frame stop codon"
     CDS             152..1306
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /EC_number="1.1.1.1"
                     /codon_start=1
                     /product="alcohol dehydrogenase 6B (class V)"
                     /protein_id="NP_001398420.1"
                     /db_xref="GeneID:100417514"
                     /db_xref="MGI:MGI:2446626"
                     /translation="

MEQASLATKTSSNVIRCRAAVAWTTNAPLSIEEVEVDPPKAGEVRVKIIASGICGTDNHTLEGKMKTPFPVILGHEGAGVVESVGPGVTTVKPGDKVLMFPLPECRECFYCLYPKGNFCEKENILSPTGLMLDGTSRFTCRGKKIYNIMGTSTFTEYTVVHEIAVAKIEAAAPMDTVCIMSCAVPTGFGAVFNTAQVTPGSSCVVFGLGGIGSAIVMACKASGACRIIGVDINEEKFPRARALGVTDCLNPNKLKKPVQEVVKEMTGVGVDFAFEAIGLIETMVAALKSCNRSYGVCVIMGVAPTGSQLSFDPLVLLPGRTLKSSVLGGYKTRDDIPKLVTDYVQKKINIDPLITHRLPFPKINEGFRLLQEGKCIRCVLSMRP"

     misc_feature    179..1297
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="Medium chain reductase/dehydrogenase
                     (MDR)/zinc-dependent alcohol dehydrogenase-like family;
                     Region: MDR; cl16912"
                     /db_xref="CDD:450120"
     misc_feature    order(311..319,326..328,695..697,707..709,770..787,
                     842..847,857..859,902..904,977..982,1049..1054,1124..1132)
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /note="NAD(P) binding site [chemical binding]; other site"
                     /db_xref="CDD:176178"
     exon            191..292
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            293..431
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            432..519
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            520..739
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            740..1000
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1136
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1275
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..1462
                     /gene="Adh6b"
                     /gene_synonym="Adh5b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agtccgccctgcatttactctctgaggtgttaaatgtgcagagcttggtaggacactcccgtatacgtggcacttcggcaggtagaggcagtccagcaggtaaccgcttgagacagaagagccctccagtctaaaccttccagaagcaaagatggaacaagccagcctcgccacaaaaacatccagcaatgtcatcagatgccgggcagctgttgcctggaccactaatgccccgctgtccattgaggaggttgaagttgatccaccaaaggctggtgaggttcgagttaagattatagcctctgggatctgtggcactgataatcataccttagaagggaaaatgaaaacgccatttcctgtcatcctgggccacgagggagctggagttgtggagagtgttggaccaggtgtaaccactgtaaagccaggagataaagtcttaatgttccctcttccggaatgtcgagaatgcttctactgcctctaccctaagggcaacttctgtgagaaagaaaatattctctctccaactggattaatgttggatggaaccagcagatttacctgcagagggaagaaaatctataatataatggggaccagcacgttcacggaatatactgtggtgcatgagattgcagtggcgaagatcgaggctgctgcccctatggatacagtctgcatcatgagctgcgcggtgccgacaggctttggagctgtgtttaacacagctcaggtcacccctggctcttcctgtgtggtgtttggactcggaggaattggctctgccatcgtcatggcctgcaaagcctctggagcatgtagaatcatcggggttgacatcaatgaggagaaatttcctcgggcaagagccttgggggtcaccgactgtctcaaccctaacaagctgaagaagcctgtgcaggaggtggtgaaggaaatgacaggggttggtgttgactttgcctttgaggccatcggactcattgaaaccatggttgcggctttgaagtcatgcaataggagctacggagtgtgtgtgattatgggagtagctccgaccggttcccagctctcttttgacccattggtacttctccctggaagaaccctaaaatcttctgttttgggagggtataaaaccagagatgacatccctaaactagtaactgactacgttcaaaagaaaattaatatagatcctcttataacccatagactgcctttcccaaaaatcaatgaaggattcagattgttgcaagagggaaaatgcatccgttgtgtcctctctatgagaccctgatggtgaccggcacacgggcatctcagcagtgctcttctatgcttctttacctccttggagattaaactgcaaactatggagatcagaacaggaaacacacacacacaattttaacgaattaaactgttaaagaaaataaactatctcaaaactctt

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