LOCUS       NM_001190445            1076 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus Fanconi anemia core complex associated protein 20
            (Faap20), transcript variant 1, mRNA.
ACCESSION   NM_001190445
VERSION     NM_001190445.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1076)
  AUTHORS   Zhang T, Wilson AF, Mahmood Ali A, Namekawa SH, Andreassen PR,
            Ruhikanta Meetei A and Pang Q.
  TITLE     Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell
            Depletion in Mice Under Genotoxic Stress
  JOURNAL   Stem Cells 33 (7), 2320-2330 (2015)
   PUBMED   25917546
REFERENCE   2  (bases 1 to 1076)
  AUTHORS   Lin Q, Donahue SL, Moore-Jarrett T, Cao S, Osipovich AB and Ruley
            HE.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK011291.1 and AL670413.19.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC096420.1, AK011291.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                AK011291.1         2-95
            95-95               AL670413.19        208712-208712
            96-891              AK011291.1         96-891
            892-892             AL670413.19        215155-215155
            893-1072            AK011291.1         892-1071
            1073-1076           AL670413.19        215336-215339
FEATURES             Location/Qualifiers
     source          1..1076
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 86.17 cM"
     gene            1..1076
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /note="Fanconi anemia core complex associated protein 20"
                     /db_xref="GeneID:67513"
                     /db_xref="MGI:MGI:1914763"
     exon            1..97
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..596
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /note="isoform a is encoded by transcript variant 1;
                     likely orthologue of H. sapiens chromosome 1 open reading
                     frame 86 (C1orf86); Fanconi anemia-associated protein of
                     20 kDa; FANCA-associated protein of 20 kDa"
                     /codon_start=1
                     /product="Fanconi anemia core complex-associated protein
                     20 isoform a"
                     /protein_id="NP_001177374.1"
                     /db_xref="CCDS:CCDS57317.1"
                     /db_xref="GeneID:67513"
                     /db_xref="MGI:MGI:1914763"
                     /translation="

MEEERRLRGRLSRRRPPAGGGPPNCRPWFLSEGSKSEPWAALLRSTVSGTADWTPNRQPLPPLPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGSSRHLFCEPEGSLGSPTPSLKGCPALNSGRTPSAQECVPVQSPLALLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDVVW"

     misc_feature    36..125
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3UN58.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    135..470
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /note="FAAP20 FANCA interaction domain; Region:
                     FANCA_interact; pfam15751"
                     /db_xref="CDD:434907"
     misc_feature    183..305
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /note="propagated from UniProtKB/Swiss-Prot (Q3UN58.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    390..392
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q6NZ36; propagated from
                     UniProtKB/Swiss-Prot (Q3UN58.2); phosphorylation site"
     misc_feature    483..587
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /note="Ubiquitin-binding zinc-finger; Region: UBZ_FAAP20;
                     pfam15750"
                     /db_xref="CDD:434906"
     exon            98..242
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            243..523
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            524..1076
                     /gene="Faap20"
                     /gene_synonym="2610002J02Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

aagtctcacttccgccggacgctgtttggagaaggatggaggaggagcggagactgcgggggaggctgagccgtcggaggccgcccgcggggggcgggccccctaactgccgcccttggtttctctcggagggaagtaagagtgagccctgggctgctctgttgcgcagcaccgtgagcgggaccgcggattggaccccgaaccgtcagccattaccaccgctgcctgcttttcccagccaggagtctctacctgacccagagtccactgtgcctcctgaggccttcactgtgggatccaagactttctcctggacgcctttgccacctgcccttcgtggctctggaagctcccgccacctgttctgtgaacctgaaggctccctggggtcacctactccatccctgaaaggatgccctgcactaaattctggtcgaactcccagcgcccaggagtgtgtgcctgtgcagagtccacttgcgttgctgagttgcccgttgtgccagaaggcgtttgacccgaagctgacccagctagatgtggatagccaccttgctcagtgcttggctgagtgcaccgaagatgtggtgtggtgagcatcagggtgccttgctgtatctccttcaaacctacacaccgacattggatgtggcttctgagacatcgtcgtgtggacacctgagtattggctccttctggttttgttcatgggcattggacataatgctggtcactgacagcaggcagcactgatcctctgtggactcatcttcattgtcagcctgacaggatgtggaatcacccaggagacacatctcaggtgtgcctgtgaaaccgttcccagagattacctgggacaggaagtcccagctgaatgtgggtggcaccgtggcctggggtcccactgattgaaaagggaaaatggagaaattgagctgtttcctcactggggatgtgatgagatgcaccgctcgcctgctacggcagccatagctacttttgctactgtgccctccttgccacagggactgtaccttaactgtgagccagaataaattttaagttgctttccagta

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