ver.2
Home
|
Help
|
Advanced search
Previous release (v1)
2025-12-08 13:20:45, GGRNA.v2 : RefSeq release 232 (Sep, 2025)
LOCUS NR_029489 82 bp RNA linear PRI 11-SEP-2024
DEFINITION Homo sapiens microRNA 19a (MIR19A), microRNA.
ACCESSION NR_029489
VERSION NR_029489.1
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 82)
AUTHORS Luo,J., Wang,L., Cui,C., Chen,H., Zeng,W. and Li,X.
TITLE MicroRNA-19a-3p inhibits endothelial dysfunction in atherosclerosis
by targeting JCAD
JOURNAL BMC Cardiovasc Disord 24 (1), 394 (2024)
PUBMED 39080547
REMARK GeneRIF: MicroRNA-19a-3p inhibits endothelial dysfunction in
atherosclerosis by targeting JCAD.
Publication Status: Online-Only
REFERENCE 2 (bases 1 to 82)
AUTHORS Fernandez-Sanjurjo,M., Pinto-Hernandez,P., Davalos,A.,
Diaz-Martinez,A.E., Martin-Hernandez,R., Castilla-Silgado,J.,
Toyos-Rodriguez,C., Whitham,M., Amado-Rodriguez,L.,
Muniz-Albaiceta,G., Terrados,N., Fernandez-Garcia,B. and
Iglesias-Gutierrez,E.
TITLE Next-generation sequencing reveals that miR-16-5p, miR-19a-3p,
miR-451a, and miR-25-3p cargo in plasma extracellular vesicles
differentiates sedentary young males from athletes
JOURNAL Eur J Sport Sci 24 (6), 766-776 (2024)
PUBMED 38874986
REMARK GeneRIF: Next-generation sequencing reveals that miR-16-5p,
miR-19a-3p, miR-451a, and miR-25-3p cargo in plasma extracellular
vesicles differentiates sedentary young males from athletes.
REFERENCE 3 (bases 1 to 82)
AUTHORS Chen,H., Li,X., Chen,W., Wu,T. and Liu,S.
TITLE LncRNA HOTAIR Inhibits miR-19a-3p to Alleviate Foam Cell Formation
and Inflammatory Response in Atherosclerosis
JOURNAL Int J Med Sci 21 (3), 521-529 (2024)
PUBMED 38250607
REMARK GeneRIF: LncRNA HOTAIR Inhibits miR-19a-3p to Alleviate Foam Cell
Formation and Inflammatory Response in Atherosclerosis.
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 82)
AUTHORS Yang,X., Luo,Y., Li,M., Jin,Z., Chen,G. and Gan,C.
TITLE Long non-coding RNA NBR2 suppresses the progression of colorectal
cancer by downregulating miR-19a to regulate M2 macrophage
polarization
JOURNAL Chin J Physiol 66 (6), 546-557 (2023)
PUBMED 38149567
REMARK GeneRIF: Long non-coding RNA NBR2 suppresses the progression of
colorectal cancer by downregulating miR-19a to regulate M2
macrophage polarization.
REFERENCE 5 (bases 1 to 82)
AUTHORS Du,L., Dou,K., Zhang,D., Xia,H., Liang,N., Wang,N., Sun,J. and
Bai,R.
TITLE MiR-19a-3p Promotes Aerobic Glycolysis in Ovarian Cancer Cells via
IGFBP3/PI3K/AKT Pathway
JOURNAL Folia Biol (Praha) 69 (5-6), 163-172 (2023)
PUBMED 38583177
REMARK GeneRIF: MiR-19a-3p Promotes Aerobic Glycolysis in Ovarian Cancer
Cells via IGFBP3/PI3K/AKT Pathway.
REFERENCE 6 (bases 1 to 82)
AUTHORS Griffiths-Jones,S., Grocock,R.J., van Dongen,S., Bateman,A. and
Enright,A.J.
TITLE miRBase: microRNA sequences, targets and gene nomenclature
JOURNAL Nucleic Acids Res 34 (Database issue), D140-D144 (2006)
PUBMED 16381832
REFERENCE 7 (bases 1 to 82)
AUTHORS Ota,A., Tagawa,H., Karnan,S., Tsuzuki,S., Karpas,A., Kira,S.,
Yoshida,Y. and Seto,M.
TITLE Identification and characterization of a novel gene, C13orf25, as a
target for 13q31-q32 amplification in malignant lymphoma
JOURNAL Cancer Res 64 (9), 3087-3095 (2004)
PUBMED 15126345
REFERENCE 8 (bases 1 to 82)
AUTHORS Dostie,J., Mourelatos,Z., Yang,M., Sharma,A. and Dreyfuss,G.
TITLE Numerous microRNPs in neuronal cells containing novel microRNAs
JOURNAL RNA 9 (2), 180-186 (2003)
PUBMED 12554860
REMARK Erratum:[RNA. 2003 May;9(5):631-2]
REFERENCE 9 (bases 1 to 82)
AUTHORS Mourelatos,Z., Dostie,J., Paushkin,S., Sharma,A., Charroux,B.,
Abel,L., Rappsilber,J., Mann,M. and Dreyfuss,G.
TITLE miRNPs: a novel class of ribonucleoproteins containing numerous
microRNAs
JOURNAL Genes Dev 16 (6), 720-728 (2002)
PUBMED 11914277
REFERENCE 10 (bases 1 to 82)
AUTHORS Lagos-Quintana,M., Rauhut,R., Lendeckel,W. and Tuschl,T.
TITLE Identification of novel genes coding for small expressed RNAs
JOURNAL Science 294 (5543), 853-858 (2001)
PUBMED 11679670
COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation
provided by NCBI staff in collaboration with miRBase. The reference
sequence was derived from AL162375.24.
This sequence is a reference standard in the RefSeqGene project.
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
that are involved in post-transcriptional regulation of gene
expression in multicellular organisms by affecting both the
stability and translation of mRNAs. miRNAs are transcribed by RNA
polymerase II as part of capped and polyadenylated primary
transcripts (pri-miRNAs) that can be either protein-coding or
non-coding. The primary transcript is cleaved by the Drosha
ribonuclease III enzyme to produce an approximately 70-nt stem-loop
precursor miRNA (pre-miRNA), which is further cleaved by the
cytoplasmic Dicer ribonuclease to generate the mature miRNA and
antisense miRNA star (miRNA*) products. The mature miRNA is
incorporated into a RNA-induced silencing complex (RISC), which
recognizes target mRNAs through imperfect base pairing with the
miRNA and most commonly results in translational inhibition or
destabilization of the target mRNA. The RefSeq represents the
predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
Sequence Note: This record represents a predicted microRNA
stem-loop as defined by miRBase. Some sequence at the 5' and 3'
ends may not be included in the intermediate precursor miRNA
produced by Drosha cleavage.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript is intronless :: LM608162.1 [ECO:0000345]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-82 AL162375.24 23217-23298
FEATURES Location/Qualifiers
source 1..82
/organism="Homo sapiens"
/mol_type="transcribed RNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q31.3"
gene 1..82
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/note="microRNA 19a"
/db_xref="GeneID:406979"
/db_xref="HGNC:HGNC:31574"
/db_xref="MIM:609418"
/db_xref="miRBase:MI0000073"
precursor_RNA 1..82
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/product="microRNA 19a"
/db_xref="GeneID:406979"
/db_xref="HGNC:HGNC:31574"
/db_xref="MIM:609418"
/db_xref="miRBase:MI0000073"
exon 1..82
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/inference="alignment:Splign:2.1.0"
variation 1
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:1594014031"
variation 2
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="t"
/db_xref="dbSNP:750595412"
variation 6
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="t"
/db_xref="dbSNP:2501246793"
variation 7..10
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="ct"
/replace="ctct"
/db_xref="dbSNP:761092550"
variation 7
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:1477297925"
variation 9
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="t"
/db_xref="dbSNP:1168187778"
variation 10..12
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="t"
/replace="tgt"
/db_xref="dbSNP:1875275146"
variation 10
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="g"
/replace="t"
/db_xref="dbSNP:2501246842"
ncRNA 14..35
/ncRNA_class="miRNA"
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/product="hsa-miR-19a-5p"
/db_xref="miRBase:MIMAT0004490"
/db_xref="GeneID:406979"
/db_xref="HGNC:HGNC:31574"
/db_xref="MIM:609418"
/db_xref="miRBase:MI0000073"
variation 14
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1875275359"
variation 15
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:756288295"
variation 16
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="t"
/db_xref="dbSNP:1566344357"
variation 18
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="t"
/db_xref="dbSNP:1875275939"
variation 19
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="t"
/db_xref="dbSNP:1051963210"
variation 20
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="g"
/replace="t"
/db_xref="dbSNP:1875276298"
variation 21
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="t"
/db_xref="dbSNP:780315531"
variation 22
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:1162564162"
variation 24
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:2501246925"
variation 26
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="t"
/db_xref="dbSNP:1170543143"
variation 28
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="g"
/db_xref="dbSNP:1388542964"
variation 31
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1442807536"
variation 33
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="c"
/db_xref="dbSNP:1403138754"
variation 35..42
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="aagaa"
/replace="aagaagaa"
/db_xref="dbSNP:764765453"
variation 36
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1341300736"
variation 38
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="t"
/db_xref="dbSNP:2501247020"
variation 40
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="g"
/db_xref="dbSNP:2501247031"
variation 46
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:1399638017"
variation 47
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:2501247050"
ncRNA 49..71
/ncRNA_class="miRNA"
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/product="hsa-miR-19a-3p"
/db_xref="miRBase:MIMAT0000073"
/db_xref="GeneID:406979"
/db_xref="HGNC:HGNC:31574"
/db_xref="MIM:609418"
/db_xref="miRBase:MI0000073"
variation 49
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="g"
/replace="t"
/db_xref="dbSNP:750154321"
variation 51..66
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="tgcaaa"
/replace="tgcaaatctatgcaaa"
/db_xref="dbSNP:2501247069"
variation 52
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:749350150"
variation 53
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="g"
/db_xref="dbSNP:1875278335"
variation 55
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:890231900"
variation 58
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1323869733"
variation 60
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:1182598123"
variation 67
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="c"
/db_xref="dbSNP:755092873"
variation 68
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="g"
/db_xref="dbSNP:1265327793"
variation 70
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:778783279"
variation 71
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:748058730"
variation 72..77
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="tgg"
/replace="tggtgg"
/db_xref="dbSNP:1875279684"
variation 72
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:771832462"
variation 77
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="a"
/replace="g"
/db_xref="dbSNP:772879142"
variation 78
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="t"
/db_xref="dbSNP:993053169"
variation 80
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="t"
/db_xref="dbSNP:1257895319"
variation 82
/gene="MIR19A"
/gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG;
MIRH1; MIRHG1; MIRN19A; miRNA19A"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:374554651"
ORIGIN
gcagtcctctgttagttttgcatagttgcactacaagaagaatgtagttgtgcaaatctatgcaaaactgatggtggcctgc
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]