LOCUS       NM_204889               1268 bp    mRNA    linear   VRT 19-SEP-2023
DEFINITION  Gallus gallus LIM homeobox 2 (LHX2), mRNA.
ACCESSION   NM_204889
VERSION     NM_204889.1
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 1268)
  AUTHORS   Tang H, Finn RD and Thomas PD.
  TITLE     TreeGrafter: phylogenetic tree-based annotation of proteins with
            Gene Ontology terms and other annotations
  JOURNAL   Bioinformatics 35 (3), 518-520 (2019)
   PUBMED   30032202
REFERENCE   2  (bases 1 to 1268)
  AUTHORS   Burge S, Kelly E, Lonsdale D, Mutowo-Muellenet P, McAnulla C,
            Mitchell A, Sangrador-Vegas A, Yong SY, Mulder N and Hunter S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1268)
  AUTHORS   Avraham O, Hadas Y, Vald L, Zisman S, Schejter A, Visel A and Klar
            A.
  TITLE     Transcriptional control of axonal guidance and sorting in dorsal
            interneurons by the Lim-HD proteins Lhx9 and Lhx1
  JOURNAL   Neural Dev 4, 21 (2009)
   PUBMED   19545367
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1268)
  AUTHORS   Nohno T, Kawakami Y, Wada N, Ishikawa T, Ohuchi H and Noji S.
  TITLE     Differential expression of the two closely related LIM-class
            homeobox genes LH-2A and LH-2B during limb development
  JOURNAL   Biochem Biophys Res Commun 238 (2), 506-511 (1997)
   PUBMED   9299541
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB005882.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB005882.1, HAEK01102847.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA103992428, SAMEA103992559
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1268
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="17"
                     /map="17"
     gene            1..1268
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /note="LIM homeobox 2"
                     /db_xref="CGNC:762"
                     /db_xref="GeneID:395705"
     exon            1..126
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..1209
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /note="LIM homeodomain"
                     /codon_start=1
                     /product="LIM/homeobox protein Lhx2"
                     /protein_id="NP_990220.1"
                     /db_xref="CGNC:762"
                     /db_xref="GeneID:395705"
                     /translation="

MLFHSLSGSEMHGVIDEMDRRTKTEAAAISSAIDRGETETQTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDNLVYCRLHFETLIQGEYQVHFNHSDVAAGKGPALGAGSANTLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDGDHLDRDQQYPSNQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKTSDSTLQAGTPSGPASEISNASMSPSSTPTTLTDLTNPTMPTVTSVLTSVPGSLEVHESRSPSQTTLTNLF"

     misc_feature    136..327
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /note="The first LIM domain of Lhx2; Region: LIM1_Lhx2;
                     cd09469"
                     /db_xref="CDD:188853"
     misc_feature    order(166..168,175..177,229..231,238..240,247..249,
                     256..258,313..315,322..324)
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188853"
     misc_feature    340..516
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /note="The second LIM domain of Lhx2 and Lhx9 family;
                     Region: LIM2_Lhx2_Lhx9; cd09377"
                     /db_xref="CDD:188763"
     misc_feature    order(352..354,361..363,418..420,427..429,436..438,
                     445..447,502..504,511..513)
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188763"
     misc_feature    787..957
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            127..332
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /inference="alignment:Splign:2.1.0"
     exon            333..715
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /inference="alignment:Splign:2.1.0"
     exon            716..921
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1268
                     /gene="LHX2"
                     /gene_synonym="LH-2A"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

tcagcgatgcttttccacagcctgtccggctcggagatgcacggtgtcatcgacgagatggatcggagaaccaaaaccgaagcagcggccatcagctcggctatagacaggggagagaccgaaacgcagaccatgccttccatcagcagtgaccgggctgccttgtgcgccggctgcgggggaaaaatctccgaccgttattacctcctggctgtggacaaacagtggcacatgcgctgcctgaagtgctgtgaatgtaaactcaacctggagtccgagctcacctgcttcagcaaggacggcagcatttactgcaaggaggattactacaggagattttcggtgcagagatgtgcgagatgtcacctggggatttctgcctctgaaatggtcatgagggccagggatttggtatatcacttaaattgcttcacttgcaccacttgcaacaagatgctgaccaccggcgaccacttcggcatgaaggacaatctggtgtattgccgcctccatttcgagactctcatccaaggggagtaccaggtgcatttcaatcactcggatgtagctgctgggaagggcccagcgttgggtgcgggctctgctaatactttgggactgccttattataacggcgtggggactgtccagaaggggagacccaggaaaaggaagagcccagggcctggggcagatctggcagcctacaacgcagctttaagctgcaatgaaaacgatggtgaccacctggatagagaccagcaataccccagcaatcaaaaaacaaagcgtatgaggacatcattcaaacaccaccagttgcggacaatgaagtcatactttgctattaaccacaatcctgatgccaaggacttgaaacagctagctcagaaaactggcctgaccaaaagagttcttcaggtttggtttcaaaatgctcgagccaaattcagacggaacctcttacgtcaagaaaacacaggggtggataagacttcagattcaacactccaagcagggaccccatcaggtcctgcatcagaaatatccaatgcctccatgagtccatccagcactcccactactttaacggacttgactaatcctactatgcctactgtgacatctgtcttgacgtcagtgcccggaagtcttgaggtccatgaatcccgaagtccttcacagacaactctcacaaatcttttctgatgactcttctccaataatttctttaaaaaagaaattattcttagttgaaattccaagtg

//