LOCUS       NM_001177738            1648 bp    mRNA    linear   VRT 23-SEP-2023
DEFINITION  Gallus gallus fascin actin-bundling protein 2, retinal (FSCN2),
            mRNA.
ACCESSION   NM_001177738 XM_426754
VERSION     NM_001177738.2
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 1648)
  AUTHORS   Tang H, Finn RD and Thomas PD.
  TITLE     TreeGrafter: phylogenetic tree-based annotation of proteins with
            Gene Ontology terms and other annotations
  JOURNAL   Bioinformatics 35 (3), 518-520 (2019)
   PUBMED   30032202
REFERENCE   2  (bases 1 to 1648)
  AUTHORS   Burge S, Kelly E, Lonsdale D, Mutowo-Muellenet P, McAnulla C,
            Mitchell A, Sangrador-Vegas A, Yong SY, Mulder N and Hunter S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAENSK010000317.1.
            
            On Sep 23, 2021 this sequence version replaced NM_001177738.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GU907099.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN05341171 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-902               JAENSK010000317.1  3926866-3927767     c
            903-1059            JAENSK010000317.1  3925622-3925778     c
            1060-1181           JAENSK010000317.1  3925425-3925546     c
            1182-1349           JAENSK010000317.1  3925175-3925342     c
            1350-1648           JAENSK010000317.1  3924808-3925106     c
FEATURES             Location/Qualifiers
     source          1..1648
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="18"
                     /map="18"
     gene            1..1648
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="fascin actin-bundling protein 2, retinal"
                     /db_xref="CGNC:16285"
                     /db_xref="GeneID:429198"
     exon            1..902
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..1555
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="fascin homolog 2, actin-bundling protein, retinal"
                     /codon_start=1
                     /product="fascin-2"
                     /protein_id="NP_001171209.1"
                     /db_xref="CGNC:16285"
                     /db_xref="GeneID:429198"
                     /translation="

MPTNGIHQVLKIQFGLINCESRYLTAESFGYKVNASAPSLKRKQIWTLEQDEADSSVVFLKSHLGRYLGADKDGQVRCEAEQPGRDERFSIITQSDGRWALQSAPHRRFFGGREDRLSCFAPSITEGELWTVHLAMHPQANLLSVSRRRYAHLSAHEDEIATDSNLPWGVDALITLCFQDKKYSLRTADERYLRCDGILVPEPGARTGYTLEFKAGKLAFKDCDGKYLAPTGPTGTLKSGRSSKPGKDELFDLEESHPQVVFTAANGRFVSIRQGVNVSANQDEELNHETFQLQIDRDTKKCSLHTNAGSYWTLVAHGGIQAVATEVAANTMFDIEWRGRRVALRASNGRYVCTKRNGQLAAVSDAVGEDEEFTLKLINRPMLVLRGEHGFVCYHRGSNLLDSNRSVYDVFHVGFSDGAYQIRGQGGKFWYVASSGAVCSDGDLSEDFFFEFRERGRVAIKGKNGRYLRGDPAGTLRADSESVLRATLWEY"

     misc_feature    98..487
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="first fascin-like domain, beta-trefoil fold, found
                     in fascin-2 and similar proteins; Region:
                     beta-trefoil_FSCN2_rpt1; cd23345"
                     /db_xref="CDD:467453"
     misc_feature    order(110..112,119..121,125..127,221..223,227..229,
                     251..253,257..259,350..352,374..376,380..382,473..475)
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:467453"
     misc_feature    order(197..205,212..214,482..484)
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="putative actin-binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:467453"
     misc_feature    488..844
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="second fascin-like domain, beta-trefoil fold, found
                     in fascin-2 and similar proteins; Region:
                     beta-trefoil_FSCN2_rpt2; cd23349"
                     /db_xref="CDD:467457"
     misc_feature    710..724
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:467457"
     misc_feature    848..1216
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="third fascin-like domain, beta-trefoil fold, found
                     in fascin-2 and similar proteins; Region:
                     beta-trefoil_FSCN2_rpt3; cd23353"
                     /db_xref="CDD:467461"
     misc_feature    order(1094..1096,1202..1216)
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="putative actin-binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:467461"
     misc_feature    1217..1552
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="fourth fascin-like domain, beta-trefoil fold, found
                     in fascin-2 and similar proteins; Region:
                     beta-trefoil_FSCN2_rpt4; cd23357"
                     /db_xref="CDD:467465"
     misc_feature    order(1217..1222,1316..1318,1322..1324,1331..1333,
                     1337..1339,1424..1429)
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="putative actin-binding site 2 [polypeptide
                     binding]; other site"
                     /db_xref="CDD:467465"
     misc_feature    1235..1249
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /note="putative actin-binding site 1 [polypeptide
                     binding]; other site"
                     /db_xref="CDD:467465"
     exon            903..1059
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1181
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1349
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1648
                     /gene="FSCN2"
                     /gene_synonym="fascin-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

cattgcggcagcggcgcccggcagcgcagacgtccccgcagccccctggggccgcccccccccccggcagaggcggaagatgccaacgaatgggatccaccaggtcctgaagatccagttcgggctgatcaactgcgagagccgctacctgacggcggagagcttcggctacaaggtgaacgcctcggcgcccagcctgaagcgcaagcagatatggacgctggagcaggacgaggccgacagctccgtcgtcttcctcaagagccacctgggccgctacctgggggccgacaaggacgggcaggtgcgctgcgaggccgagcagccgggccgcgatgagcgcttcagcatcatcacgcagtcggacgggcgctgggcgctgcagtcggcgccgcaccggcgcttcttcggcggccgcgaggaccggctgtcctgcttcgcgcccagcatcaccgagggcgagctgtggaccgtgcacctggccatgcacccgcaggccaacctgctgagcgtcagccgccgccgctacgcgcacctgagcgcccacgaggacgagatcgccaccgacagcaacctgccctggggggtggacgcgctcatcacgctctgcttccaggacaagaagtacagcctgcgcaccgccgacgagcgctacctgcgctgcgatgggatcctggtgcccgagcccggcgcccgcaccggatacacgctggagttcaaggcgggcaagctggccttcaaggactgtgacgggaagtacctggcgcccaccgggcccaccggcacgctcaagtccgggcgcagctccaagccgggcaaggacgaactcttcgatctggaggagagtcacccccaggtggtgttcacggcagccaacggcagattcgtctccatccggcagggcgtcaacgtgtcggccaaccaggacgaggagctgaaccacgagaccttccagctgcagatcgaccgtgacaccaagaagtgcagcctgcacaccaacgctggcagctactggaccctggtggcccacgggggcatccaggctgtggccaccgaagttgctgccaacaccatgtttgacatcgagtggcgcgggcggcgcgtggccctgcgtgccagcaacggccgctatgtgtgcaccaagaggaacgggcagctggcggccgtcagcgacgccgtgggggaggacgaggagttcaccctgaagctgatcaaccggcccatgctggtgctgcggggcgagcacggcttcgtctgctaccaccgcggctccaacctgctcgactccaaccgctccgtctacgacgtcttccacgtgggcttcagcgacggcgcctatcagatccgaggtcaggggggaaagttctggtacgtggcgagcagcggggcggtctgcagcgacggggacctctccgaggatttcttcttcgagttccgggagcgcgggcgcgtcgccatcaaagggaagaacgggcggtacctgcgtggggacccggccggcaccctgcgggccgacagcgagtcggtgctgcgggccacgctctgggaatactgagcccggggacggggggacccggtggcaccgatggcagcagccgcgtcccccaccctccccaactcacgtcattaaagtgcgtctggattgcag

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