LOCUS       XM_005158556            3679 bp    mRNA    linear   VRT 08-SEP-2024
DEFINITION  PREDICTED: Danio rerio NRDE-2, necessary for RNA interference,
            domain containing (nrde2), mRNA.
ACCESSION   XM_005158556
VERSION     XM_005158556.5
DBLINK      BioProject: PRJNA13922
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_007128.7) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 8, 2024 this sequence version replaced XM_005158556.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_000002035.6-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/15/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3679
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
     gene            1..3679
                     /gene="nrde2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 EST, 22 long SRA reads, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 57 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:794348"
                     /db_xref="ZFIN:ZDB-GENE-111117-3"
     misc_feature    1
                     /gene="nrde2"
                     /experiment="COORDINATES: cap analysis [ECO:0007248]"
                     /note="transcription start site"
     CDS             37..3504
                     /gene="nrde2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="XP_005158613.1"
                     /db_xref="GeneID:794348"
                     /db_xref="ZFIN:ZDB-GENE-111117-3"
                     /translation="

MALFPSFSGLSGSNSSAESKAPADLEWLSNQSFSTEDALKTHQRATDRARAETEEPAGTSEEKHKERGDNHGKSKKRKKEKKKKHKKKRSRDNSESSGFESDTIYPSDLLKKENTDREEAQVRVSETFMWLDDLQTPTDSPFCIDRRADRANWQYKSLYRGDIARYKRKGGSCLGLDLRTQAVTWTDGGPEKKRVDKKAERYFSSSTRQLLQTRGLLALPILSEGSATNSDPYIKLAVCAEEQGSSTQTPESWVNPLGIYDPGTTLWLEGKGQPEVKGEQQSTEAQESNSTLLSARVEEFNRNLRENPTDIKLWLDFVHFQDELAFGSGSFSSAGDCDAEMRKMSLRAVLEKKLSIMDRAVESNPSDVDLKLEKLRLCKELWEPAVLQKEWKKLVFIHPNSAPLWKKYLLFTQSHFSTFSVSKVNGVFGKCLSTLSAVQDGSMVSHPPLPGTQEDLLDIFLQQCHFLRQAGHTEKAVCLFQALLDFTFFKPDNVKNLATRQQVDFFEPFWDSGEPRIGERGARGWKAWMLQQEKGGWVIPPEPDDDEEEEQEDSEIKDKTWPKWKIWLDVEASREANQWLPWRPDKTKGQSEEDCEDPDRQVLFDDIGPSMIRVDRADLQAQLILAFLQFLGLPGALTKFFTASSSSFLLDDLTFLEEGPDPERPLTSYDLPVTGICAVGHMTCLSGCRRQAGLCKAGEEFLHNVLHQTLRLVPAQDQAAITLCWLQYEKLKVLRCLRSGNKRQMKSQGKRSKRLAKRLLKEPENRGSLALWREYAHLEWLLGNLEEARKVFDTALSMGVSRGLNDHVLCKLCFLYAQLEVEQALSSETVSTFSKAVYILTKLAEGASYTPFSGQINPVVILKARKAYEQALLSILPEQNTDSNAGASKKHNRTSSLIGCFGLFQYLTMGIDAAQAVYSQAIQKLIPSHFNSEAAEGSRRRSTIFADCEAVAVQHVALLRHHTNTNVFPLSRLRLALTDALSLLPSSASLWHLYLQTENHYHSAGRTRRFFHSMAKKTDSVVPYLFAITAEQRLKQLLDSVQRSRLPGEALPTLPVNGLSNRIRCLFESATGTEHGAHCPLLWRMYLNFMVCDGNADRGSGIFYKALQEVPWVKGLYMDAVQLFPERVQEFLDLMTEKELRLRMPMEEVDILLEE"

     misc_feature    457..744
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(457..483,490..495,505..510,514..516,520..564,
                     571..579,583..591,613..621,631..636,640..645,652..672,
                     691..702,721..744)
                     /gene="nrde2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    931..1932
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
     polyA_site      3679
                     /gene="nrde2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

attatcccgcgtctgttttgatgtattagaagcagcatggctctgttcccgtccttctctggactgtcaggcagcaacagctctgcagaaagtaaagctccagcggatctggaatggctgagtaatcagagcttcagcactgaagatgctttgaagactcaccagcgagccacagacagagcccgagcagagacagaggaaccggcaggcacaagtgaggagaagcataaagagagaggagacaaccatggaaaatcgaagaaaagaaagaaagaaaaaaagaaaaaacacaaaaagaagaggagcagagataactctgaaagtagtgggttcgaatcagacaccatatatcccagtgaccttctaaaaaaggagaacactgacagagaggaagctcaagttcgggtgagcgagacctttatgtggctggatgacctccagacccccactgactcccccttctgcatcgacaggagagctgaccgtgccaactggcaatacaaatccctttataggggagacatagccaggtataaaaggaagggaggctcgtgtctagggttggacttgagaacgcaggctgtgacctggactgatggaggaccagagaagaagcgagtggacaagaaagcagaacgctatttctcttcttccacccgtcagctgcttcaaacaaggggtctgctagctttgcctatactctctgaaggcagcgccaccaactctgatccctatataaaacttgcagtctgtgctgaagaacagggctcttctacccaaacacctgaatcatgggtcaatccgctgggcatttatgatcctggaaccaccttgtggctggagggcaagggccagccggaggtcaagggagaacaacagagcactgaggcccaagagagcaacagcactcttctgagcgctcgagtggaggagtttaacaggaacctacgggagaatcctacagacatcaagctgtggttggactttgtacactttcaggatgagctggccttcggttctgggtctttctcttctgccggtgactgtgatgcagaaatgaggaagatgtctctacgtgctgtgctggagaagaagctctccatcatggacagagcagtggaaagtaacccttctgacgttgacctgaaattagaaaaactccgtctgtgcaaggagttatgggagcctgccgtcctgcagaaagagtggaagaaactagtgttcattcatccaaacagcgcacctttatggaagaagtatctgctcttcacacagagccatttcagcaccttctcagtgtctaaggtcaatggagttttcggcaagtgtctgagcacgcttagtgcagtccaggatggcagcatggtgtctcaccctccacttccaggcacacaggaagacctcttggatatctttctgcagcagtgccatttcctgcgtcaggcaggtcatacagagaaagctgtttgcctttttcaagccctactggacttcactttcttcaagccagacaatgtaaagaatctggccaccagacaacaggtggatttttttgagccattttgggacagtggagagcccaggattggggagcggggggctcgcggatggaaggcttggatgcttcaacaggagaaaggaggatgggtgattccacctgagccagatgatgacgaagaggaagagcaggaggactctgagatcaaagacaaaacttggcctaagtggaagatctggttagatgtggaggcgtcccgagaggcaaaccaatggctgccatggagaccagataaaaccaagggccaatcagaagaggactgcgaggacccagacagacaggtcttatttgatgatattggcccatccatgattcgtgttgacagagcagatctccaggcgcagctaattctggcattcctgcagttcctcggtctccccggagctctaaccaagttctttacagcatcttcttctagctttctgctggacgatctcaccttccttgaagagggccctgatccggagcgaccactgacctcttatgacctcccagtgactgggatctgtgctgtgggtcacatgacatgtcttagtggatgcaggaggcaagcagggctgtgtaaagctggagaggagtttcttcacaatgttttgcatcaaactctccgactggtccctgcacaggatcaagctgctattactctgtgctggctgcagtacgagaaactcaaggtgctgaggtgtttacgaagtggaaataaaagacaaatgaagtctcaggggaagcgcagtaaacgtcttgcaaaaaggctgctaaaggagccagagaacaggggcagtctggcactttggagagaatatgcccatctggagtggcttctaggaaatctggaagaggctcgaaaagtttttgacactgctttgagtatgggtgtttctaggggtcttaatgaccatgttctctgcaagctctgctttctttacgcccagctagaggtagaacaggctttaagcagtgaaacagtttctacattctccaaagctgtctacattctgactaaattagcagaaggtgcttcctacactcctttctctggccagatcaacccagtggtcatattgaaggccagaaaggcctatgagcaggccctgttgagtattttacccgaacagaacacagacagcaatgctggagcttcaaagaaacacaataggacgtccagtctaattggatgttttggactttttcagtacctaacaatggggatcgatgcagcacaagctgtgtacagtcaggccatccaaaaactcattcccagccatttcaattcagaagcagcagagggatctcggagaagatccacgatctttgcggactgtgaggctgttgctgtccagcatgtagcactgctgcgccatcacactaacactaatgtgttccccctatcccgactgagactggcacttacagatgcgctctccttactgccctccagtgcctcattatggcatctctacctgcaaacagagaaccactaccacagcgcaggccgaactcgcaggttctttcacagcatggcaaagaaaactgacagtgttgtgccgtatctcttcgccatcactgcagaacaacgtcttaaacagttgctggactctgtgcaaaggtctcgtcttcctggtgaagctcttcccaccctgccagtgaatggtcttagcaatcgtatccgttgtctgtttgaaagcgctacaggaacagagcatggagcccactgtcctctgctgtggagaatgtatctgaacttcatggtgtgtgatgggaatgcagacagaggcagtggaatcttttacaaggctttacaggaagtgccctgggtaaagggcttgtacatggatgcagtgcagctgtttcctgaacgtgtgcaggagtttttagacctcatgactgagaaggagttgcgtctgagaatgcccatggaggaggtggacatcctgctggaggagtagccatcaaacccttcccgtaatacaccagaatcaacaaccgctgttcattagccaacagaaacagaatctctctcaacaaacagtaaaaaaaataattaattacagattttatttatttttatccatttctaaatgtattttttgtaattttgagattaaataatgtttcatttaa

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