LOCUS       NM_213351               1597 bp    mRNA    linear   VRT 15-OCT-2021
DEFINITION  Danio rerio calmodulin 1a (calm1a), mRNA.
ACCESSION   NM_213351
VERSION     NM_213351.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1597)
  AUTHORS   Can H, Chanumolu SK, Gonzalez-Munoz E, Prukudom S, Otu HH and
            Cibelli JB.
  TITLE     Comparative analysis of single-cell transcriptomics in human and
            Zebrafish oocytes
  JOURNAL   BMC Genomics 21 (1), 471 (2020)
   PUBMED   32640983
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1597)
  AUTHORS   Xue Y, Liu D, Cui G, Ding Y, Ai D, Gao S, Zhang Y, Suo S, Wang X,
            Lv P, Zhou C, Li Y, Chen X, Peng G, Jing N, Han JJ and Liu F.
  TITLE     A 3D Atlas of Hematopoietic Stem and Progenitor Cell Expansion by
            Multi-dimensional RNA-Seq Analysis
  JOURNAL   Cell Rep 27 (5), 1567-1578 (2019)
   PUBMED   31042481
REFERENCE   3  (bases 1 to 1597)
  AUTHORS   Sahu SU, Visetsouk MR, Garde RJ, Hennes L, Kwas C and Gutzman JH.
  TITLE     Calcium signals drive cell shape changes during zebrafish
            midbrain-hindbrain boundary formation
  JOURNAL   Mol Biol Cell 28 (7), 875-882 (2017)
   PUBMED   28148652
REFERENCE   4  (bases 1 to 1597)
  AUTHORS   Wu M, Wu D, Wang C, Guo Z, Li B and Zuo Z.
  TITLE     Hexabromocyclododecane exposure induces cardiac hypertrophy and
            arrhythmia by inhibiting miR-1 expression via up-regulation of the
            homeobox gene Nkx2.5
  JOURNAL   J Hazard Mater 302, 304-313 (2016)
   PUBMED   26476318
REFERENCE   5  (bases 1 to 1597)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1597)
  AUTHORS   Mueller RL, Huang C and Ho RK.
  TITLE     Spatio-temporal regulation of Wnt and retinoic acid signaling by
            tbx16/spadetail during zebrafish mesoderm differentiation
  JOURNAL   BMC Genomics 11, 492 (2010)
   PUBMED   20828405
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1597)
  AUTHORS   Sato Y, Hashiguchi Y and Nishida M.
  TITLE     Temporal pattern of loss/persistence of duplicate genes involved in
            signal transduction and metabolic pathways after teleost-specific
            genome duplication
  JOURNAL   BMC Evol Biol 9, 127 (2009)
   PUBMED   19500364
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 1597)
  AUTHORS   Pujic Z, Omori Y, Tsujikawa M, Thisse B, Thisse C and Malicki J.
  TITLE     Reverse genetic analysis of neurogenesis in the zebrafish retina
  JOURNAL   Dev Biol 293 (2), 330-347 (2006)
   PUBMED   16603149
REFERENCE   9  (bases 1 to 1597)
  AUTHORS   Friedberg F and Taliaferro L.
  TITLE     Calmodulin genes in zebrafish (revisited)
  JOURNAL   Mol Biol Rep 32 (1), 55-60 (2005)
   PUBMED   15865211
REFERENCE   10 (bases 1 to 1597)
  AUTHORS   Friedberg F and Rhoads AR.
  TITLE     Multiple calmodulin genes in fish
  JOURNAL   Mol Biol Rep 29 (4), 377-382 (2002)
   PUBMED   12549824
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC053150.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053150.1, CK028287.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505371, SAMEA3505372
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1597
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     gene            1..1597
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /note="calmodulin 1a"
                     /db_xref="GeneID:406660"
                     /db_xref="ZFIN:ZDB-GENE-030131-8308"
     exon            1..69
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    25..27
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /note="upstream in-frame stop codon"
     CDS             67..516
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /EC_number="2.7.11.19"
                     /note="CALMx2"
                     /codon_start=1
                     /product="calmodulin-1a"
                     /protein_id="NP_998516.1"
                     /db_xref="GeneID:406660"
                     /db_xref="ZFIN:ZDB-GENE-030131-8308"
                     /translation="

MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK"

     misc_feature    67..513
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /note="calmodulin; Provisional; Region: PTZ00184"
                     /db_xref="CDD:185504"
     exon            70..100
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /inference="alignment:Splign:2.1.0"
     exon            101..244
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /inference="alignment:Splign:2.1.0"
     exon            245..351
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /inference="alignment:Splign:2.1.0"
     exon            352..487
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /inference="alignment:Splign:2.1.0"
     exon            488..1541
                     /gene="calm1a"
                     /gene_synonym="CaMbeta; sb:cb617; wu:fb08d09; wu:fb69c08;
                     wu:fj34a08; zgc:63926"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggagagcggagcatcgctgcagtctagagtagattaacaaacccagtccactctccaccctcagacatggctgaccaactcaccgaggagcaaattgcagagtttaaggaggctttctccttatttgataaggatggtgatggtactatcaccaccaaggagctgggcacagtgatgcgctcgctcggacagaaccccacagaagctgaactccaggacatgataaacgaggtggacgctgatggtaacggaaccattgactttcctgaatttctgacaatgatggcccggaaaatgaaagacacagacagcgaggaggagatccgcgaagctttccgagtgtttgacaaggacgggaacggctacatcagtgcggcagagcttcgccatgtcatgacaaacctgggtgagaaactaacagatgaagaggtggatgaaatgatcagagaagctgacatcgacggtgacggtcaggtcaattacgaagaatttgtacaaatgatgacggcaaagtgaagctcttctgttttctcctgacctctttagaagacaaaaaaaaaatcagtcaaatgttttacttacctcttacgcaaaaatattcatttattcatactgtttctgtatagaaaaaaactgaatgttgaaaaaaggaaaatgtccatatatagaaaaaaatatatttaaaaacacaaaaacaaaaaaagacataaccaaacataaatgacctgcatgtactggttagtggtcctgttcccaaagaactgcttagacatctacgaaaaagatcaatcaattaatcctgatatcgaaccttcagaaactaaagtaaaagcatctggtgaactgcttaactggttccatttgctagtggtgatgtttgggctggccaatcgtcttctacttcctgtttctgttttacatgcatgcagcttgagtctggagccgctattggggcggaaaacctcagcgatgtctgtcggagcgttctgggggagaattttaaaagagggttgactggtttcgggggaggcgggatcgggtggagggtggtttttctgaatctgcatagtggacgaatgaatgggacctttgcagtttgcttcaataactaaataaagagatatttttaagaaaaatgagcagttaagagattttaaactacgtttggcatgtcaggatatttggagttttgtttctttgtgcattgtgcccgatagtaggggcgtttagcgggagggagtggcttgggagtttcagggcgtgacctttcaccttatgtggaagtgttttttcgggtaagggcaacggtgactgactgtaccattaaaatgtttttaatctttagttcttctctgggctctgatcgtgagcatgtcgaattattattattttgtttttttctctctggagagcgcgaaagagggcttttggccaccaggggtttgtttcgactgcccaccttcagttctgtttatgttcattccaagttgtacatgctcgtcttttgatttttttttccaataaaagaacatgaacttgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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