LOCUS       NM_200774               1430 bp    mRNA    linear   VRT 12-APR-2020
DEFINITION  Danio rerio required for meiotic nuclear division 5 homolog B
            (rmnd5b), mRNA.
ACCESSION   NM_200774
VERSION     NM_200774.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Ma JX, Li JY, Fan DD, Feng W, Lin AF, Xiang LX and Shao JZ.
  TITLE     Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking
            Protein That Involves in Multiple Innate Immune Signaling Pathways
            in a Zebrafish Model
  JOURNAL   Front Immunol 9, 1327 (2018)
   PUBMED   29942316
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1430)
  AUTHORS   Sun XJ, Xu PF, Zhou T, Hu M, Fu CT, Zhang Y, Jin Y, Chen Y, Chen
            SJ, Huang QH, Liu TX and Chen Z.
  TITLE     Genome-wide survey and developmental expression mapping of
            zebrafish SET domain-containing genes
  JOURNAL   PLoS ONE 3 (1), e1499 (2008)
   PUBMED   18231586
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1430)
  AUTHORS   Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y,
            Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT and
            Chen Z.
  TITLE     Hematopoietic gene expression profile in zebrafish kidney marrow
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (46), 16240-16245 (2004)
   PUBMED   15520368
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC059606.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059606.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="wild-type"
                     /db_xref="taxon:7955"
                     /chromosome="14"
                     /map="14"
     gene            1..1430
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /note="required for meiotic nuclear division 5 homolog B"
                     /db_xref="GeneID:393747"
                     /db_xref="ZFIN:ZDB-GENE-040426-1744"
     exon            1..22
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
     exon            23..196
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    46..48
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /note="upstream in-frame stop codon"
     CDS             58..1233
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /EC_number="2.3.2.27"
                     /codon_start=1
                     /product="E3 ubiquitin-protein transferase RMND5B"
                     /protein_id="NP_957068.1"
                     /db_xref="GeneID:393747"
                     /db_xref="ZFIN:ZDB-GENE-040426-1744"
                     /translation="

MEQCACVERELEKVLHRFVTYGHQSEERLDELLNNVCELRSRLLAYGVQDADLSVLHQTMAQCCKEIKETVQMLASRHKDIHGSVSKVGKAIDRNFDAEVSAVVAENVWDSPERQKYLSETIVEHLYRQGMLSVAEDLCQESGVVIDMSMKQPFLELNRILEALRTQDLRPALEWAVTNRQRLLDLNSTLEFKLHRLYFISLLNGGIGKQQEALQYARHFQPFASQHQRDIQILMGSLVYLRHGIENSPYRSLLETDQWAEICNIFTRDACALLGLSVESPLSVSFASGCMALPVLMNIKQVIEQRQCSGVWTHKDELPIEIDLGKKCWYHSVFACPILRQQTSESNPPMKLICGHVISRDALNKLTNAGKLKCPYCPMEQNPSDAKQIYF"

     misc_feature    514..948
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /note="CTLH/CRA C-terminal to LisH motif domain; Region:
                     CTLH; pfam10607"
                     /db_xref="CDD:402305"
     misc_feature    1054..1230
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /note="Degenerated RING finger found in protein RMD5
                     homolog B (RMD5B); Region: dRING_RMD5B; cd16795"
                     /db_xref="CDD:438449"
     exon            197..339
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
     exon            340..477
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
     exon            478..578
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
     exon            579..745
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
     exon            746..911
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1014
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1169
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1411
                     /gene="rmnd5b"
                     /gene_synonym="zgc:73277"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ctggtgaactggtgtcaaacaggacgtggtgtgtgtgtgtgtttgtaagctgtgctgatggagcagtgtgcgtgtgtggagcgagaactggagaaggtgctgcaccggttcgtcacatatggacatcagtcagaggaacggctggacgaactcctaaataacgtctgtgagctgaggagtcgactgctcgcttatggtgttcaggatgcagatctctcagtgctgcatcaaaccatggcccagtgctgtaaggagatcaaggaaaccgtgcagatgcttgcctccagacacaaggacatccacggcagcgtgtccaaagtgggcaaagccatcgacagaaattttgatgcggaggtgagtgcagtagttgctgagaatgtgtgggactctccagagaggcagaaatacctcagtgaaaccatcgttgaacacctgtatcgacagggcatgctgagtgttgcagaagacctctgccaggagtctggtgtagtaatcgacatgagcatgaaacaaccctttctggagctcaaccgcattttagaggctttaagaacacaagatctcagaccggctttagaatgggcagtgacgaaccgtcagcggctgctggatctgaacagcacccttgagtttaagctgcacagactgtatttcatcagcctgctcaatgggggcatcggcaaacagcaggaggcgctacagtacgctcgacatttccaacccttcgcctcacagcatcagagagatattcagatcttaatgggcagtcttgtgtacctccgccatgggatcgagaactctccgtaccgcagtcttctggagacggaccagtgggctgagatctgtaacatcttcacacgcgacgcttgtgctctgcttggcctctctgtagagtctccactcagtgtcagttttgcgtccggctgtatggcacttcctgtgctcatgaacatcaagcaggtcattgaacagagacagtgcagcggggtttggacacataaggatgagctgccaattgaaatagacctgggaaagaagtgctggtatcactcagtgttcgcctgtcctatcctgaggcagcaaacatcagagagcaatcctcccatgaagctcatctgtggacacgtcatatccagagacgctctgaacaaactcaccaatgctggaaagcttaaatgcccgtattgtccaatggagcagaatccctcagatgccaaacagatctacttctgatgtctctctcctctctcttctggatgaaacgttgaaggcagttccgatgattctccttcaaaggcaatgatgagcctccagtggtggattcaacccctgaaaacgccgccaccttcctctccaaagctttcgtttccagaggcgggtggccacggcagcgttcctgtagatgcaaagttaaaaaaaaaaaaaaaaaa

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