LOCUS       NM_131765               1955 bp    mRNA    linear   VRT 08-OCT-2023
DEFINITION  Danio rerio claudin e (cldne), mRNA.
ACCESSION   NM_131765
VERSION     NM_131765.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1955)
  AUTHORS   Mo C, Li W, Jia K, Liu W and Yi M.
  TITLE     Proper Balance of Small GTPase rab10 Is Critical for PGC Migration
            in Zebrafish
  JOURNAL   Int J Mol Sci 22 (21), 11962 (2021)
   PUBMED   34769390
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1955)
  AUTHORS   Phatak M, Kulkarni S, Miles LB, Anjum N, Dworkin S and Sonawane M.
  TITLE     Grhl3 promotes retention of epidermal cells under endocytic stress
            to maintain epidermal architecture in zebrafish
  JOURNAL   PLoS Genet 17 (9), e1009823 (2021)
   PUBMED   34570762
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1955)
  AUTHORS   Hou Y, Lee HJ, Chen Y, Ge J, Osman FOI, McAdow AR, Mokalled MH,
            Johnson SL, Zhao G and Wang T.
  TITLE     Cellular diversity of the regenerating caudal fin
  JOURNAL   Sci Adv 6 (33), eaba2084 (2020)
   PUBMED   32851162
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1955)
  AUTHORS   Liu H, Duncan K, Helverson A, Kumari P, Mumm C, Xiao Y, Carlson JC,
            Darbellay F, Visel A, Leslie E, Breheny P, Erives AJ and Cornell
            RA.
  TITLE     Analysis of zebrafish periderm enhancers facilitates identification
            of a regulatory variant near human KRT8/18
  JOURNAL   Elife 9, e51325 (2020)
   PUBMED   32031521
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1955)
  AUTHORS   Li EB, Truong D, Hallett SA, Mukherjee K, Schutte BC and Liao EC.
  TITLE     Rapid functional analysis of computationally complex rare human
            IRF6 gene variants using a novel zebrafish model
  JOURNAL   PLoS Genet 13 (9), e1007009 (2017)
   PUBMED   28945736
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1955)
  AUTHORS   Clelland ES and Kelly SP.
  TITLE     Tight junction proteins in zebrafish ovarian follicles: stage
            specific mRNA abundance and response to 17beta-estradiol, human
            chorionic gonadotropin, and maturation inducing hormone
  JOURNAL   Gen Comp Endocrinol 168 (3), 388-400 (2010)
   PUBMED   20553723
REFERENCE   7  (bases 1 to 1955)
  AUTHORS   Siddiqui M, Sheikh H, Tran C and Bruce AE.
  TITLE     The tight junction component Claudin E is required for zebrafish
            epiboly
  JOURNAL   Dev Dyn 239 (2), 715-722 (2010)
   PUBMED   20014098
  REMARK    GeneRIF: important for zebrafish epiboly
REFERENCE   8  (bases 1 to 1955)
  AUTHORS   Reischauer S, Levesque MP, Nusslein-Volhard C and Sonawane M.
  TITLE     Lgl2 executes its function as a tumor suppressor by regulating ErbB
            signaling in the zebrafish epidermis
  JOURNAL   PLoS Genet 5 (11), e1000720 (2009)
   PUBMED   19911055
REFERENCE   9  (bases 1 to 1955)
  AUTHORS   Day KR and Jagadeeswaran P.
  TITLE     Microarray analysis of prothrombin knockdown in zebrafish
  JOURNAL   Blood Cells Mol Dis 43 (2), 202-210 (2009)
   PUBMED   19442542
REFERENCE   10 (bases 1 to 1955)
  AUTHORS   Loh YH, Christoffels A, Brenner S, Hunziker W and Venkatesh B.
  TITLE     Extensive expansion of the claudin gene family in the teleost fish,
            Fugu rubripes
  JOURNAL   Genome Res 14 (7), 1248-1257 (2004)
   PUBMED   15197168
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF359425.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF359425.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1955
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="15"
                     /map="15"
     gene            1..1955
                     /gene="cldne"
                     /gene_synonym="cb84; cldn28a; fb16e12; wu:fb16e12"
                     /note="claudin e"
                     /db_xref="GeneID:81584"
                     /db_xref="ZFIN:ZDB-GENE-010328-5"
     exon            1..1939
                     /gene="cldne"
                     /gene_synonym="cb84; cldn28a; fb16e12; wu:fb16e12"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..678
                     /gene="cldne"
                     /gene_synonym="cb84; cldn28a; fb16e12; wu:fb16e12"
                     /codon_start=1
                     /product="claudin e"
                     /protein_id="NP_571840.1"
                     /db_xref="GeneID:81584"
                     /db_xref="ZFIN:ZDB-GENE-010328-5"
                     /translation="

MVSMCREILGMCLAIIGFLGAIIICALPMWKVTAFIGANIVTAQTIWEGLWMNCVMQSTGQMQCKIYDSLLALPQDLQAARALVVIAIIVSFFALILGIAGGKCTNFVEREDAKAKVSIASGVIFIIAGVLVLVPVCWSANTIIRDFYNPLLTDAQRREMGASLYIGWGVAALLIIGGGILCSSCPPKDEKYNMKYSQPRSTATSRAYV"

     misc_feature    58..591
                     /gene="cldne"
                     /gene_synonym="cb84; cldn28a; fb16e12; wu:fb16e12"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
     regulatory      1914..1919
                     /regulatory_class="polyA_signal_sequence"
                     /gene="cldne"
                     /gene_synonym="cb84; cldn28a; fb16e12; wu:fb16e12"
ORIGIN      

cagaaaacacacgttcaacttcacaagcccacaaacaaacaagcaaacatggtgtctatgtgccgagagatcctgggcatgtgcctggccatcattggcttcttgggagccattattatttgtgctttgcccatgtggaaggtgaccgcgttcatcggagccaacatcgtgacggcgcagaccatctgggagggtttgtggatgaactgtgtgatgcagagcacgggacagatgcagtgtaagatctacgactcgctcctggccttgcctcaggacctgcaggccgctcgagctctcgtggtcatcgccatcatcgtcagctttttcgcgctcatcctgggcatcgccggcgggaaatgcaccaacttcgtggaaagggaagacgccaaggctaaagtgtccatcgccagcggcgtgatcttcatcattgctggagttctggtgctggtgcctgtttgctggtccgccaacaccatcatcagagatttctacaatcctctgctcacggatgctcagcggagggagatgggggcttcgctgtacatcggatggggcgtcgcagcgctgctgatcatcggaggtggaatcctgtgcagctcctgccctccaaaagatgaaaaatacaacatgaaatactcccagccgcgctccaccgccaccagcagagcctacgtctgagagctacgccgagatcgcaaagacttttggagactctctctcactctttcgttctaagacttgccaagaagatcaattgaaagactgtgtctgatattgcatatatagtggttatatagtgaggatgtatatatgtgctgtgattatacacacttttgagctgaatgaacacaactcttgagatttctgttggcacaacttaactgtttcatgtcaaattcacttaacggctaataacttaatcgatttgtgttgtgccgacgtgaatgaactgtgtggaagcctgcatttgttttacagcgtgcactcaagaaaatgatgtttgcagatgttttggaaaataatgcttgccgtttgttcaaactactcatttgaaatgagctgaaacaacacaattcttgagtttctttgggacaacctaattgttttatgctcaattcaattaaaattgttaaaaaataataagcttacttaattcattgatgttccattatcaaaaattgactaaataaacttaattgttggtggttcattccactgtggcgaccctggattaataaaattattttaaaaaataattagctaacataattcattgatgttccaccaacaaaatttgactaaataaacttatttgttggcggtttattccactgtggcgaccctggattaataaaaaaattattaaaaaaaaaacaaaaaagctaacttaattccttggttttccaccatcaaaaattgactaaataaacttaatactcggtggttgattccattgtggcgaataaaattataaaaaacatattaagctaagttaattccttgatgttttcccaacgtaatttgattaagttaacttagttgagtggattcaacataaaacaattaggttttccctccaaaaaactcaagctaattttaaataagtagtttgaagaaggcatttattgagtgcagatccctgaaagagaaaaatgtgcatttataatgtgattttattcaatatttttggttgatttttagtttttttttaacaatgcattcttataatatacgtttaatatgacgagagaaatagtttctttaaatgtaagacgtaagctttaatactgtaaagattaaatgtgcattaacttagcttttgtgtttgtttgtcagtgtataaattaactttttttttgcataaagatgtgttaatcagtaaaactgtcctgatatttgtttttgtttattataataaatggttctgtaaaactgtaaaaaaaaaaaaaaaaaaa

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