LOCUS       NM_001020506             918 bp    mRNA    linear   VRT 16-SEP-2023
DEFINITION  Danio rerio taste receptor, type 2, member 203 (tas2r203), mRNA.
ACCESSION   NM_001020506
VERSION     NM_001020506.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 918)
  AUTHORS   Kowatschew D and Korsching SI.
  TITLE     An Ancient Adenosine Receptor Gains Olfactory Function in Bony
            Vertebrates
  JOURNAL   Genome Biol Evol 13 (9) (2021)
   PUBMED   34499158
REFERENCE   2  (bases 1 to 918)
  AUTHORS   Behrens M, Di Pizio A, Redel U, Meyerhof W and Korsching SI.
  TITLE     At the Root of T2R Gene Evolution: Recognition Profiles of
            Coelacanth and Zebrafish Bitter Receptors
  JOURNAL   Genome Biol Evol 13 (1) (2021)
   PUBMED   33355666
REFERENCE   3  (bases 1 to 918)
  AUTHORS   Ohmoto M, Okada S, Nakamura S, Abe K and Matsumoto I.
  TITLE     Mutually exclusive expression of Galphaia and Galpha14 reveals
            diversification of taste receptor cells in zebrafish
  JOURNAL   J Comp Neurol 519 (8), 1616-1629 (2011)
   PUBMED   21452212
REFERENCE   4  (bases 1 to 918)
  AUTHORS   Oike H, Nagai T, Furuyama A, Okada S, Aihara Y, Ishimaru Y, Marui
            T, Matsumoto I, Misaka T and Abe K.
  TITLE     Characterization of ligands for fish taste receptors
  JOURNAL   J Neurosci 27 (21), 5584-5592 (2007)
   PUBMED   17522303
REFERENCE   5  (bases 1 to 918)
  AUTHORS   Go Y.
  CONSRTM   SMBE Tri-National Young Investigators
  TITLE     Proceedings of the SMBE Tri-National Young Investigators' Workshop
            2005. Lineage-specific expansions and contractions of the bitter
            taste receptor gene repertoire in vertebrates
  JOURNAL   Mol Biol Evol 23 (5), 964-972 (2006)
   PUBMED   16484289
REFERENCE   6  (bases 1 to 918)
  AUTHORS   Ishimaru Y, Okada S, Naito H, Nagai T, Yasuoka A, Matsumoto I and
            Abe K.
  TITLE     Two families of candidate taste receptors in fishes
  JOURNAL   Mech Dev 122 (12), 1310-1321 (2005)
   PUBMED   16274966
REFERENCE   7  (bases 1 to 918)
  AUTHORS   Pfister P and Rodriguez I.
  TITLE     Olfactory expression of a single and highly variable V1r pheromone
            receptor-like gene in fish species
  JOURNAL   Proc Natl Acad Sci U S A 102 (15), 5489-5494 (2005)
   PUBMED   15809442
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY764272.1.
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="9"
                     /map="9"
     gene            1..918
                     /gene="tas2r203"
                     /gene_synonym="T2R1; tas2r1l; tas2r4"
                     /note="taste receptor, type 2, member 203"
                     /db_xref="GeneID:553135"
                     /db_xref="ZFIN:ZDB-GENE-050510-3"
     CDS             1..918
                     /gene="tas2r203"
                     /gene_synonym="T2R1; tas2r1l; tas2r4"
                     /note="taste receptor, type 2, member 4; bitter taste
                     receptor; taste receptor, type 2, member 1 like; zfT2R4"
                     /codon_start=1
                     /product="taste receptor, type 2, member 203"
                     /protein_id="NP_001018342.1"
                     /db_xref="GeneID:553135"
                     /db_xref="ZFIN:ZDB-GENE-050510-3"
                     /translation="

MEPWLYALISSPLCLIGMVFNLLFFFCLMRPVSGVTLRNPLRFLLIVVLVNSTFQYLVIAVTIIMLLFDYIFWLETVTRALIYQFFCGNFLCNAWISIFYYISIVPQHHAIFIWIKRNIKAILYGGFILNQIVLTFAISTGAVTYFFLGPVPVNFTALELNSTALAQTLEADMFLFHVANFSYLLYCTCPLVTLIVSWGKTFFYLRGHMKKMGQSGESFSQPQQKSQMRVTVTGMVQAALFLPSSLWTVAAALLYITGLFEEVDPSRFITMTFCSLSSLGNLLCFGFSQSVFRRGIVSVIKKLKG"

     misc_feature    160..>669
                     /gene="tas2r203"
                     /gene_synonym="T2R1; tas2r1l; tas2r4"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; Region: 7tm_GPCRs; cl28897"
                     /db_xref="CDD:475119"
     misc_feature    235..294
                     /gene="tas2r203"
                     /gene_synonym="T2R1; tas2r1l; tas2r4"
                     /note="TM helix 3 [structural motif]; Region: TM helix 3"
                     /db_xref="CDD:410628"
     misc_feature    379..429
                     /gene="tas2r203"
                     /gene_synonym="T2R1; tas2r1l; tas2r4"
                     /note="TM helix 4 [structural motif]; Region: TM helix 4"
                     /db_xref="CDD:410628"
     misc_feature    517..597
                     /gene="tas2r203"
                     /gene_synonym="T2R1; tas2r1l; tas2r4"
                     /note="TM helix 5 [structural motif]; Region: TM helix 5"
                     /db_xref="CDD:410628"
     exon            1..918
                     /gene="tas2r203"
                     /gene_synonym="T2R1; tas2r1l; tas2r4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atggagccatggctgtacgctttaatctccagtcccctctgcctcataggcatggttttcaacctcctcttctttttctgcctcatgcggccagtctccggagtgacgcttcgtaatccactgcgcttcttgttaattgttgtgctcgtcaattctacatttcaatatctggtcatagccgtgaccattattatgcttctttttgattacattttctggctggaaacagttaccagagctctgatttatcaattcttttgcggaaacttcttgtgcaatgcctggatcagcattttctactacatatcaattgttcctcaacatcatgccatcttcatctggattaagaggaatattaaagctattttatatgggggcttcattctaaatcaaatagtgcttacgtttgctatatctacgggggcagtgacatatttttttcttgggcccgtcccagttaattttactgcacttgaactgaactcaacagcactagcacaaaccttagaggcagacatgtttttgtttcatgtggcaaatttttcatatttgctatattgcacctgcccgttggtcacactgatagtctcttggggcaaaacttttttttatctgcgtggacatatgaaaaagatgggacagagcggcgagtctttttcccagccccagcagaagagccagatgcgagtcacagtgacaggtatggtgcaggcagcactgttcctacccagtagcctgtggacagtagcagctgctctcctctacattacaggcctctttgaagaggtggatcccagcaggtttatcacaatgactttctgctcactgtccagcttgggaaatctgctgtgtttcggattctcccagtctgtgtttcgccgtgggattgtaagtgtgattaaaaagctaaaaggttga

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