LOCUS       NM_001006029             954 bp    mRNA    linear   VRT 03-APR-2024
DEFINITION  Danio rerio trafficking protein particle complex subunit 6B
            (trappc6b), mRNA.
ACCESSION   NM_001006029
VERSION     NM_001006029.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Marin-Valencia,I., Novarino,G., Johansen,A., Rosti,B., Issa,M.Y.,
            Musaev,D., Bhat,G., Scott,E., Silhavy,J.L., Stanley,V., Rosti,R.O.,
            Gleeson,J.W., Imam,F.B., Zaki,M.S. and Gleeson,J.G.
  TITLE     A homozygous founder mutation in TRAPPC6B associates with a
            neurodevelopmental disorder characterised by microcephaly, epilepsy
            and autistic features
  JOURNAL   J Med Genet 55 (1), 48-54 (2018)
   PUBMED   28626029
REFERENCE   2  (bases 1 to 954)
  AUTHORS   Bayes,A., Collins,M.O., Reig-Viader,R., Gou,G., Goulding,D.,
            Izquierdo,A., Choudhary,J.S., Emes,R.D. and Grant,S.G.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 954)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 954)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083391.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083391.1, EH450189.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="23"
                     /map="23"
     gene            1..954
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="trafficking protein particle complex subunit 6B"
                     /db_xref="GeneID:450008"
                     /db_xref="ZFIN:ZDB-GENE-041010-122"
     exon            1..282
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    118..120
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="upstream in-frame stop codon"
     CDS             205..678
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="TRAPP complex subunit 6B; trafficking protein
                     particle complex 6b"
                     /codon_start=1
                     /product="trafficking protein particle complex subunit 6b"
                     /protein_id="NP_001006029.1"
                     /db_xref="GeneID:450008"
                     /db_xref="ZFIN:ZDB-GENE-041010-122"
                     /translation="

MADEALFQFLHSEIIQYVNSAETGESENGRCVSKLENMGFRVGQGLIERFTQDTPRFKDELDVMKFICKDFWTSVFKKQIDNLRTNHQGIYVLQDNKFRLLTQLSAGKQYLEHAPKFLAFTCGLVRGALSNIGVKSIVTAEVSVMPACKFQVMIQKM"

     misc_feature    211..669
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="Trs33 subunit of the TRAPP complex; Region:
                     TRAPPC6A_Trs33; cd14944"
                     /db_xref="CDD:271347"
     misc_feature    order(217..219,226..228,238..240,508..513,541..543,
                     553..555)
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="synbindin interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:271347"
     misc_feature    order(220..225,229..237,241..246,253..255,304..306,
                     316..318,325..330,337..342,349..351,424..426,433..435,
                     493..495,562..564)
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="BET3 interface [polypeptide binding]; other site"
                     /db_xref="CDD:271347"
     exon            283..350
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     exon            351..468
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     exon            469..552
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     exon            553..646
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     exon            647..937
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

aggaagtggaaccaatgtaaagaaggaccattcctttcaatcgaaaacactagcaaaatatttcacctataatgacattcgcacaatgaatagctgtctgtttattgaagcagcagttgatttatacctgtagtcggattggttggttctgccgttgttcgtcgccggtcagtttcagtggggcatcggctggactggctcgagatggcagatgaggctctttttcagttcctacacagtgaaatcattcagtatgtcaacagtgcagaaactggggaatcggagaatggacgatgtgtttctaaacttgagaacatgggctttcgtgtgggacaaggacttattgagaggtttacccaagacacgccacgctttaaagatgagcttgacgttatgaagttcatctgcaaagatttctggaccagtgtttttaagaagcagattgacaacctgagaacaaaccaccagggtatttatgtactacaagataacaagttccgcctactgacccaactgtctgctggcaaacagtatctggaacatgcgccgaagtttttagccttcacttgtggactggtccgaggagcactttcaaacattggtgtgaaaagtatcgtcacggcggaagtgtcagtcatgcctgcctgtaaattccaggtgatgattcagaagatgtgattcactacaatggagcatatagttcacaacgtgcatctcagttttattgccttgtcgttttttattgcctgcacattttatcaataatatcactatgaagtttttttttttaatttgcagtaacttgaaaactactggcattaaatgtattttgacatgtactgtattttttgttagtattttgacactcattatctgtccatattcactgttctgattattcatttgcactaatagcattaaagctagaatcctgctaaaaaaaaaaaaaaaaaa

//