LOCUS       NM_001004112            1180 bp    mRNA    linear   VRT 09-OCT-2022
DEFINITION  Danio rerio four and a half LIM domains 5 (fhl5), mRNA.
ACCESSION   NM_001004112
VERSION     NM_001004112.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1180)
  AUTHORS   Zhang Y, Heylen L, Partoens M, Mills JD, Kaminski RM, Godard P,
            Gillard M, de Witte PAM and Siekierska A.
  TITLE     Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish
            Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug
            Discovery
  JOURNAL   Front Mol Neurosci 15, 881933 (2022)
   PUBMED   35686059
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1180)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1180)
  AUTHORS   Luo Q, Wu C, Sun S, Lu F, Xie L, Zhao H, Zhong X and Zhou Q.
  TITLE     The spatial-temporal expression and functional divergence of bach
            homologs in zebrafish Danio rerio
  JOURNAL   J Fish Biol 88 (4), 1584-1597 (2016)
   PUBMED   26992035
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079524.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079524.1, EE695034.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505375, SAMEA4476769
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1180
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     gene            1..1180
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /note="four and a half LIM domains 5"
                     /db_xref="GeneID:445475"
                     /db_xref="ZFIN:ZDB-GENE-040822-3"
     exon            1..37
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..880
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /codon_start=1
                     /product="four and a half LIM domains protein 5"
                     /protein_id="NP_001004112.1"
                     /db_xref="GeneID:445475"
                     /db_xref="ZFIN:ZDB-GENE-040822-3"
                     /translation="

MSTERFDCHYCKDTLLGKKYILKEDTQYCTKCYENLFANCCEVCSLPIGCNCKDLSYKDRHWHENCFKCAKCSRSLVDKPFAAKDELMLCTECYSHEYSSKCSTCKKTVMPGSRKMEYKGNSWHETCFLCQRCQQPIGTKSFIPKDNNYFCVPCFEKQFAYQCCACKKAITTGGVTYHDKPWHRECFTCIGCKRQLAGQRFTSRENYPYCLDCFSNLYAKKCVGCTKAITSLAGAKYISFEERQWHSECFTCMQCSVSLVGRGFLTQRDDILCTDCGREK"

     misc_feature    146..322
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /note="The first LIM domain of Four and a half LIM domains
                     protein (FHL); Region: LIM1_FHL; cd09343"
                     /db_xref="CDD:188729"
     misc_feature    order(158..160,167..169,224..226,233..235,242..244,
                     251..253,305..307,314..316)
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188729"
     misc_feature    341..511
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /note="LIM is a small protein-protein interaction domain,
                     containing two zinc fingers; Region: LIM; cl02475"
                     /db_xref="CDD:413332"
     misc_feature    order(341..343,350..352,407..409,416..418,425..427,
                     434..436,488..490,497..499)
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188810"
     misc_feature    524..679
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /note="The third LIM domain of Four and a half LIM domains
                     protein (FHL); Region: LIM3_FHL; cd09346"
                     /db_xref="CDD:188732"
     misc_feature    order(524..526,533..535,584..586,593..595,602..604,
                     611..613,665..667,674..676)
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188732"
     misc_feature    701..868
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /note="The fourth LIM domain of Four and a half LIM
                     domains protein (FHL); Region: LIM4_FHL; cd09347"
                     /db_xref="CDD:188733"
     misc_feature    order(701..703,710..712,773..775,782..784,791..793,
                     800..802,854..856,863..865)
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188733"
     exon            38..196
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /inference="alignment:Splign:2.1.0"
     exon            197..371
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /inference="alignment:Splign:2.1.0"
     exon            372..541
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /inference="alignment:Splign:2.1.0"
     exon            542..728
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /inference="alignment:Splign:2.1.0"
     exon            729..1156
                     /gene="fhl5"
                     /gene_synonym="zgc:92375"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ccctgaagcccttcagaagcccattcaaccaccgaagatgtctactgaaagattcgactgccattactgcaaggacactttacttggaaagaaatacatcctaaaagaggacacacagtattgcacaaaatgctacgagaatctgtttgccaactgctgcgaggtgtgttcgctgcccattggatgcaactgtaaggacctctcctacaaggaccggcactggcatgaaaattgcttcaagtgtgctaagtgcagcagatcattggtggacaaaccgtttgctgctaaagatgagcttatgctttgcaccgagtgttactctcatgagtattcctctaagtgtagcacttgcaagaagaccgtcatgccaggatcacggaaaatggagtacaaagggaacagctggcatgagacatgctttctgtgtcaacgctgtcagcagccaataggaaccaagtctttcatcccaaaagataacaattacttctgtgttccttgtttcgagaagcagtttgcctaccagtgctgtgcttgtaaaaaggccataacaactggcggtgtcacatatcacgataagccctggcaccgagagtgtttcacttgcattggatgcaagagacaactagcaggccagcgctttacctccagagaaaactacccatactgcctggactgtttcagcaatctctacgccaagaaatgcgtgggctgcaccaaggcgattactagcttggcaggtgctaaatacatctcgtttgaggagcgccagtggcacagcgagtgtttcacgtgtatgcagtgctcagtgtctctggtgggtcgtggcttccttacacagcgggacgacatactgtgcaccgactgtggcagagagaaatgagctcagacgaccacaagagcctctaccaatattgcaggagagatactgtaggcgaaatatatgtagatttagatttgggtgcataatgtttaaacatgaacaatgaaaagattcattatctgtgtcaccagctaattaggatgcttaatgttttgttgaaatagtttaaatcaaaggcaattttttgagtaattgtcttcaagaagcatggaataatattgaaattgtttgaactttgtgtgtttttaatcaataaacttgtgtcttcttcctgtcaaaaaaaaaaaaaaaaaaaaaaaa

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