LOCUS       NM_001002340            1592 bp    mRNA    linear   VRT 23-MAR-2024
DEFINITION  Danio rerio claudin 7a (cldn7a), mRNA.
ACCESSION   NM_001002340
VERSION     NM_001002340.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1592)
  AUTHORS   Garcia-Concejo,A. and Larhammar,D.
  TITLE     Protein kinase C family evolution in jawed vertebrates
  JOURNAL   Dev Biol 479, 77-90 (2021)
   PUBMED   34329618
REFERENCE   2  (bases 1 to 1592)
  AUTHORS   She,P., Zhang,H., Peng,X., Sun,J., Gao,B., Zhou,Y., Zhu,X., Hu,X.,
            Lai,K.S., Wong,J., Zhou,B., Wang,L. and Zhong,T.P.
  TITLE     The Gridlock transcriptional repressor impedes vertebrate heart
            regeneration by restricting expression of lysine methyltransferase
  JOURNAL   Development 147 (18) (2020)
   PUBMED   32988975
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1592)
  AUTHORS   Li,X., Song,G., Zhao,Y., Zhao,F., Liu,C., Liu,D., Li,Q. and Cui,Z.
  TITLE     Claudin7b is required for the formation and function of inner ear
            in zebrafish
  JOURNAL   J Cell Physiol 233 (4), 3195-3206 (2018)
   PUBMED   28834538
REFERENCE   4  (bases 1 to 1592)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1592)
  AUTHORS   Carvalho,C.M., Vasanth,S., Shinawi,M., Russell,C., Ramocki,M.B.,
            Brown,C.W., Graakjaer,J., Skytte,A.B., Vianna-Morgante,A.M.,
            Krepischi,A.C., Patel,G.S., Immken,L., Aleck,K., Lim,C.,
            Cheung,S.W., Rosenberg,C., Katsanis,N. and Lupski,J.R.
  TITLE     Dosage changes of a segment at 17p13.1 lead to intellectual
            disability and microcephaly as a result of complex genetic
            interaction of multiple genes
  JOURNAL   Am J Hum Genet 95 (5), 565-578 (2014)
   PUBMED   25439725
REFERENCE   6  (bases 1 to 1592)
  AUTHORS   Baltzegar,D.A., Reading,B.J., Brune,E.S. and Borski,R.J.
  TITLE     Phylogenetic revision of the claudin gene family
  JOURNAL   Mar Genomics 11, 17-26 (2013)
   PUBMED   23726886
REFERENCE   7  (bases 1 to 1592)
  AUTHORS   Davey,C., Tallafuss,A. and Washbourne,P.
  TITLE     Differential expression of neuroligin genes in the nervous system
            of zebrafish
  JOURNAL   Dev Dyn 239 (2), 703-714 (2010)
   PUBMED   20063411
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC075926.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC075926.1, EG576581.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1592
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="7"
                     /map="7"
     gene            1..1592
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="claudin 7a"
                     /db_xref="GeneID:436612"
                     /db_xref="ZFIN:ZDB-GENE-040718-29"
     exon            1..419
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    155..157
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="upstream in-frame stop codon"
     CDS             197..835
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="claudin 7 like"
                     /codon_start=1
                     /product="claudin-7-A"
                     /protein_id="NP_001002340.1"
                     /db_xref="GeneID:436612"
                     /db_xref="ZFIN:ZDB-GENE-040718-29"
                     /translation="

MANSGVQLLGFGLSLIGIIGLIVGTILPQWKMSAYVGDSIITAVATYQGLWMSCAFQSTGQLQCKIYDSILQLDSDLQATRALMIVGIIVSIAGLGVASIGMKCTTCGADDKVRKTRTAMTGGIILLVGALCAVVACSWFAHNVIRAFYNPFTPVNTKFEFGAAIFIAWGGSFLDVLGGAMLAASCPRSKQVSKYPKSNSTRSANGSNKEYV"

     misc_feature    206..742
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
     misc_feature    218..280
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     transmembrane region"
     misc_feature    440..502
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     transmembrane region"
     misc_feature    554..616
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     transmembrane region"
     misc_feature    683..745
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     transmembrane region"
     misc_feature    767..832
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            420..584
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /inference="alignment:Splign:2.1.0"
     exon            585..669
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /inference="alignment:Splign:2.1.0"
     exon            670..1552
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gcctataaacacatccagctgcgtgactggctgctaggttttgttttgggggaaaagttccacagcttcatcgtcagtatagtctgagcgttcctccagagaggaacaggtgcgggacaggataagggattatcgacgtttctctaaagtttattgaaaactgttgctcagcttgccatttaagcttcgaaaagaaatggcaaactcgggcgttcagttgcttgggttcggtctctctctgattggcatcattggactgatcgtgggcaccatcctgccccagtggaagatgtccgcgtatgtgggagacagtatcatcaccgcagtggccacttaccagggactgtggatgtcctgcgcatttcagagcaccggacaacttcagtgcaaaatctatgactctattctgcagctggacagtgacctgcaagcaacccgagctttgatgattgtggggatcattgtgtccattgctggtctcggtgtggccagtataggcatgaagtgcaccacttgtggagctgacgacaaagttcgcaagactcgcacggccatgactggaggcatcatacttcttgtaggagccctctgtgcagttgtcgcctgctcgtggtttgcccataatgtgatccgagcattctacaaccccttcactccagtcaacaccaagtttgagtttggagcagccattttcatagcttggggtggctcatttcttgatgttctcggtggagccatgttggctgcctcttgccctcgaagtaaacaagtgtcaaaatatcctaaaagtaactctacacgatcagccaacggcagcaacaaagagtatgtgtgagcaagactgcctctcactggacagacattgtaacagcttcaaaaggtgaagactttcttcagcagaataatcactgagcatgctgttgaagaaatgaggtgagaaacgagaaggaaaaccgctcacactgttgaatgttcccttgataaaaaagtggcaaccagttgtctaaaagtttgaataaaaatatatatttacaaactctatgggaggttttaaaatggaggattgtagaaatctagcgccagtagaaatactcacagccctcagtgcttcagctaagttgttttatgtgtgtaattaaggaggagaaacttttgatagtgggccaaatatgtcggcgttcccaaagtgtccactagggagcactagaaacaacacaatgagcaagtgtttcctaaaatgggagagatttcccagagcttttgtttgtggagtgtttatcctacaacagacgaagtgctaacattattaacactcacatgagtcattgttgtgtagtttgatgtaatcacagtgtttgaagtattataaatcttctttcttttactaaacacatttctgcattaactcacacttgtcattactttacccataagcccttttgaatactacatatagtacttataaatgcttcccgataatgtaaatgttagttaaatattgttcatacatttgtgttacatgcttattttcaataaatttgctttcatcctaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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