LOCUS       NM_001002131            1448 bp    mRNA    linear   VRT 02-APR-2024
DEFINITION  Danio rerio proteasome 26S subunit, non-ATPase 8 (psmd8), mRNA.
ACCESSION   NM_001002131
VERSION     NM_001002131.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1448)
  AUTHORS   Cahill,T., Chan,S., Overton,I.M. and Hardiman,G.
  TITLE     Transcriptome Profiling Reveals Enhanced Mitochondrial Activity as
            a Cold Adaptive Strategy to Hypothermia in Zebrafish Muscle
  JOURNAL   Cells 12 (10), 1366 (2023)
   PUBMED   37408201
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1448)
  AUTHORS   Tu,X., Wang,H.B., Huang,Q., Cai,Y., Deng,Y.P., Yong,Z., Hu,Q.,
            Feng,J., Jordan,J.B. and Zhong,S.
  TITLE     Screening Study on the Anti-Angiogenic Effects of Traditional
            Chinese Medicine - Part II: Wild Chrysanthemum
  JOURNAL   J Cancer 12 (1), 124-133 (2021)
   PUBMED   33391408
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1448)
  AUTHORS   Bayes,A., Collins,M.O., Reig-Viader,R., Gou,G., Goulding,D.,
            Izquierdo,A., Choudhary,J.S., Emes,R.D. and Grant,S.G.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1448)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1448)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX936429.8 and BX908775.18.
            
            On Aug 8, 2023 this sequence version replaced NM_001002131.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC071432.1, GFIL01031643.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA2168446,
                                           SAMEA2168447 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               BX936429.8         149402-149554
            154-226             BX936429.8         151741-151813
            227-329             BX936429.8         151900-152002
            330-495             BX936429.8         153954-154119
            496-596             BX936429.8         154200-154300
            597-708             BX936429.8         154408-154519
            709-827             BX936429.8         156714-156832
            828-1448            BX908775.18        81570-82190         c
FEATURES             Location/Qualifiers
     source          1..1448
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="18"
                     /map="18"
     gene            1..1448
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /note="proteasome 26S subunit, non-ATPase 8"
                     /db_xref="GeneID:415221"
                     /db_xref="ZFIN:ZDB-GENE-040625-136"
     exon            1..153
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    7..9
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /note="upstream in-frame stop codon"
     CDS             43..846
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /note="proteasome (prosome, macropain) 26S subunit,
                     non-ATPase, 8"
                     /codon_start=1
                     /product="26S proteasome non-ATPase regulatory subunit 8"
                     /protein_id="NP_001002131.1"
                     /db_xref="GeneID:415221"
                     /db_xref="ZFIN:ZDB-GENE-040625-136"
                     /translation="

MASVLKETAGLYETLKAEWNKKNPNLNKCGELLSKLKISLLELNFLPTTGTKLTKQQLILARDVLEIGALWSILKKDIPSFERYMAQLKCYYFDYKDELPESAYRHQLLGLNLLFLLSQNRVSEFHTELERLSAKDIQTNVYIRHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDTLLDTIRDEIAGCIEKAYEQIQFNEATRVLFFSSPKKMTDYAKKRNWTQSPDGYYSFSTQHQKTEEVTIPSTELAKQVIEYARQLEMIV"

     misc_feature    394..738
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /note="CSN8/PSMD8/EIF3K family; Region: CSN8_PSD8_EIF3K;
                     pfam10075"
                     /db_xref="CDD:462954"
     exon            154..226
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            227..329
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            330..495
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            496..596
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            597..708
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            709..1448
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gtgttctgacaggccggtgtcgtacatttttgcagaatcaccatggcgtctgtgttgaaagagactgcgggattatatgaaacattgaaagccgagtggaataaaaagaacccaaacctcaataaatgcggtgagctcttgagcaagttaaagatttccctgttggagttgaactttctaccaaccactgggaccaaactaaccaaacagcagcttatcctcgcacgagatgttttggagattggagcgctgtggagcattctgaagaaagacatcccctcatttgaacgctacatggctcagcttaaatgctactactttgattacaaggatgagttgcctgagtcggcctacaggcaccagttgctgggactaaacctgctcttcctgctctctcagaaccgagtgtctgaatttcacacagagctggaaagactgagcgcaaaggacatccagacgaacgtctacatcagacacccagtttcattagagcagtatctgatggagggcagttacaacaaggtatttcttgccaaaggaaatattcccgcggagagctacaccttctttattgatactcttcttgataccatccgagatgagattgcaggttgtatagagaaagcatatgaacagattcaattcaatgaagccacgcgggtgcttttcttttcctctccaaaaaagatgacagactatgcaaagaaaagaaactggacccagagtcctgatggatactactcattcagcacccagcatcaaaagacagaggaggtgaccatcccctccacagaactggccaaacaagtcatcgagtatgcaagacagctggaaatgattgtgtagtgtggatatttgacacatgtatacataaaggttcacatttgttcatccaaacatacaaataaaagcattgtacagtggccatatatctggactcagtttagacagcggatgacacacccacaaataatggatctcagaggcctacgaatgatcaatatctgcctgtatcagggtctcttggtatgattgtgtgttggatgtgtgttttcagtaactctcttgcattactggtgatcatctaataaccgctctaagtttttttggaaataaacatttaatacgtatagtttgaatatcaagttgttttttcccctcaatgtttaatgggttttttttaacaaaagtgagtttgagagtttggaaaagtgggtctagatagtatgttggggatggaagctaaacttcactgcttattcaatgtaatcccaggagtattcattgaattattgtactctccgccttgtatcctagcaactgtgagaggattggttaaaagtttgcagatgtttttctttgtttatcctgtaatgggataaaaatcccccaaattgtcaaaaggaagtgacagttcatagtaaataaaactgttttttctgattctt

//