LOCUS       NM_001007566            2780 bp    mRNA    linear   INV 04-MAY-2019
DEFINITION  Ciona intestinalis kinesin family member 3B (kif3b), mRNA.
ACCESSION   NM_001007566
VERSION     NM_001007566.1
KEYWORDS    RefSeq.
SOURCE      Ciona intestinalis (vase tunicate)
  ORGANISM  Ciona intestinalis
            Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
            Cionidae; Ciona.
REFERENCE   1  (bases 1 to 2780)
  AUTHORS   Still IH, Vettaikkorumakankauv AK, DiMatteo A and Liang P.
  TITLE     Structure-function evolution of the transforming acidic coiled coil
            genes revealed by analysis of phylogenetically diverse organisms
  JOURNAL   BMC Evol. Biol. 4, 16 (2004)
   PUBMED   15207008
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2780)
  AUTHORS   Satou Y, Yamada L, Mochizuki Y, Takatori N, Kawashima T, Sasaki A,
            Hamaguchi M, Awazu S, Yagi K, Sasakura Y, Nakayama A, Ishikawa H,
            Inaba K and Satoh N.
  TITLE     A cDNA resource from the basal chordate Ciona intestinalis
  JOURNAL   Genesis 33 (4), 153-154 (2002)
   PUBMED   12203911
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Ivan Still. The reference sequence was derived
            from EAAA01000249.1.
            
            Summary: The protein encoded by this gene is similar to a human
            protein that acts as a heterodimer with kinesin family member 3A to
            aid in chromosome movement during mitosis and meiosis. The human
            protein is a plus end-directed microtubule motor and can interact
            with the SMC3 subunit of the cohesin complex. In addition, the
            human protein may be involved in the intracellular movement of
            membranous organelles. This protein and kinesin family member 3A
            form the kinesin II subfamily of the kinesin superfamily. [provided
            by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK112783.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00013799, SAMD00028078
                                           [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-298               EAAA01000249.1     11770-12067         c
            299-475             EAAA01000249.1     10989-11165         c
            476-670             EAAA01000249.1     10420-10614         c
            671-788             EAAA01000249.1     10103-10220         c
            789-909             EAAA01000249.1     9659-9779           c
            910-979             EAAA01000249.1     9357-9426           c
            980-1089            EAAA01000249.1     9174-9283           c
            1090-1241           EAAA01000249.1     8790-8941           c
            1242-1369           EAAA01000249.1     8475-8602           c
            1370-1542           EAAA01000249.1     8018-8190           c
            1543-1767           EAAA01000249.1     7511-7735           c
            1768-1863           EAAA01000249.1     7285-7380           c
            1864-2003           EAAA01000249.1     6689-6828           c
            2004-2190           EAAA01000249.1     6054-6240           c
            2191-2282           EAAA01000249.1     5817-5908           c
            2283-2780           EAAA01000249.1     4924-5421           c
FEATURES             Location/Qualifiers
     source          1..2780
                     /organism="Ciona intestinalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:7719"
                     /chromosome="1"
                     /map="1"
     gene            1..2780
                     /gene="kif3b"
                     /note="kinesin family member 3B"
                     /db_xref="GeneID:493586"
     exon            1..298
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    151..153
                     /gene="kif3b"
                     /note="upstream in-frame stop codon"
     CDS             157..2391
                     /gene="kif3b"
                     /EC_number="5.6.1.3"
                     /codon_start=1
                     /product="kinesin family member 3B"
                     /protein_id="NP_001007567.1"
                     /db_xref="GeneID:493586"
                     /translation="

MSKSKSSECVKVVVRCRPLNQKEVEGNHESVVSMDVKSGQVQIKNPKSPNDPPKSFTFDAIYDWNCTQSDIFEETFHPLLDSVLNGFNGTIFAYGQTGTGKTFTMEGVRSNPELRGAIPRSFEHIYKHIARTKDQQYLVRASYLEIYQEDIRDLLSKDQSKRLELKERPDTGVYVKDLLSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEDGLDGKNHIRVGKLNLVDLAGSERQAKSGATGERLKEATKINLSLSALGNVISSLVDGKGHIPYRDSKLTRLLQDSLGGNAKTVMVANIGPASYNSDETLTTLRYANRAKNIQNKPKINEDPKDALLREFQEEIAKLKANLESRSKGGRKKKTRRRRNADGEMVEESGSDDDEDDDDDSSLSEEQQAKLEKEKNRILQDKSMAEEERERLLKEQQAKLEELKRQQEAKDELTAKIKAMQSKLLVGGRTIVDHTNEQERELEERRLLLAEQRRKERSMKQQLEAREESALEAQESYSSLRQEVDEKTKRLKKMYTRLQQLKAEISDLQEINCREREDLEISQMKMNRELKQKLLIIENFIPSDERARLEERIIYNEENDQWELKSVTNTAHNTMMQRPKSAHSGSSRPTSQYAKMAAAVGFNPRYKGDNVLLVELDMPTRTTQDYEGPTIAPKVQAALDAALQEEGDLQLDASDEKFVKKTKPRLKSAKSRPRTAKKNGISNGTDKPSLYPTSRGLVPK"

     misc_feature    178..1170
                     /gene="kif3b"
                     /note="Kinesin motor domain, kinesins II or KIF3_like
                     proteins; Region: KISc_KIF3; cd01371"
                     /db_xref="CDD:276822"
     misc_feature    order(205..207,439..441,448..450,454..465,886..888)
                     /gene="kif3b"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:276822"
     misc_feature    order(1027..1029,1036..1038,1045..1047)
                     /gene="kif3b"
                     /note="microtubule interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:276822"
     misc_feature    <1387..>1902
                     /gene="kif3b"
                     /note="Chromosome segregation ATPase Smc [Cell cycle
                     control, cell division, chromosome partitioning]; Region:
                     Smc; COG1196"
                     /db_xref="CDD:440809"
     exon            299..475
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            476..670
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            671..788
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            789..909
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            910..979
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1089
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1241
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1369
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1542
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1767
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1768..1863
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1864..2003
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2190
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2191..2282
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2283..2780
                     /gene="kif3b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2773..2778
                     /regulatory_class="polyA_signal_sequence"
                     /gene="kif3b"
ORIGIN      

ggaatttgtagtcatagtgcagtgaagtccaaacgatcaattcacatttctcatacgaacatcagaacagttatttttaaaggttgtgcgtttttggtataaagaacgaatatacacatgctggaataagtagaaagagccctaaggtcctaaagcatgtcgaaatcaaaaagttctgaatgcgtcaaagttgtggttcgttgtcgtcctttaaaccagaaagaggtagaagggaatcatgaaagcgtcgtatccatggatgtaaagtctggtcaagttcaaattaaaaaccccaaaagtccaaatgatccaccaaaatcctttactttcgatgctatctatgattggaactgcacgcaaagcgatatatttgaagaaacatttcatccactccttgattctgttctcaatggatttaatggaaccatatttgcttacggtcaaactggaacaggaaaaacgtttaccatggaaggtgttcgttcaaacccagaacttcgtggtgcaataccaagatcttttgaacatatttacaaacatatcgcacgaaccaaagaccagcaatacttggtgcgcgcttcttatctagaaatttaccaagaagatatcagagatttattgtcaaaagatcaaagcaaaagattagaacttaaagaaagaccagatacaggtgtatatgttaaagatcttttgtcttttgtaacaaaatctgtgaaagaaattgaacatgttatgaatgttggaaaccaaaaccgcagtgttggtgcaaccaacatgaatgaacatagctcacgatcccacgcaatatttgtgatcaccattgaatgtagtgaggatggtctggatggaaagaatcacattcgagttgggaaattaaacttggttgatcttgctggaagtgaaagacaagcaaaatctggtgcgacaggagaaagattgaaagaagcaacaaaaattaatttatctctttctgctcttgggaacgttatttcatcactggtggatggtaaggggcatattccgtatcgagattccaaacttacaaggttattgcaagactcacttggtggaaatgctaaaactgtgatggttgccaacattggaccagcaagttataactcggatgaaactttaaccacattaagatacgccaacagagctaaaaatattcaaaataaaccaaagattaatgaagatcctaaagatgccttactgagggagttccaggaggaaatagcaaaattaaaagcaaatcttgaaagtcgttcaaaaggtggaagaaaaaagaaaacgagaagaagaagaaatgcagacggagagatggtggaagagtccgggagtgatgatgatgaggatgatgatgatgatagtagtttatcagaggagcaacaagccaagttggagaaggagaagaaccgaatcttgcaagataagagcatggctgaggaggaaagagaaaggttgttaaaggaacaacaagcaaaactagaagagctgaagaggcaacaggaagctaaagatgaactgactgcaaagataaaagcgatgcaaagcaaactcctcgttggtggaagaaccatcgtggatcatacgaatgagcaagagcgagagctggaggagcggaggttgcttctagctgagcagagaaggaaagaacgatcgatgaaacaacaacttgaggcaagggaggagtcagcactcgaggcgcaagagagctacagttcgttgagacaggaagttgatgaaaaaaccaaacgactgaaaaagatgtacaccagacttcagcaacttaaagctgaaataagtgacctgcaagaaataaattgtcgggaacgagaagacctggagatttctcaaatgaagatgaacagagagttaaagcagaagttgttgatcattgaaaactttattccaagtgatgagagagctcgcttggaggagagaattatttataatgaagaaaatgatcaatgggagctgaaatctgtaacaaacacagctcataatacaatgatgcaacgtccgaaaagtgcccacagtggcagcagtcgacctacttctcagtatgcaaagatggctgctgcagttggtttcaatcctcgatacaaaggtgacaacgtattactggtggagttggacatgcccactcgaacaacacaagattatgaagggcctaccattgcaccaaaggttcaagcagcattagatgcagctttgcaggaggaaggtgatttacaacttgatgcgagtgatgagaagtttgtaaagaaaactaaaccaagactaaagtcggcaaaatctcgtccccgtacagcaaagaagaatggaatatcaaacgggacggacaaaccatcgttgtatccaacatctcggggtttagttccaaaataaatttcacagtttgattttaatccaatcatacaatttctataaagaaggccaattaaactaaaaaatacatattaatatatagggttaagctttattgtgtgaaagctttgtttagatcataaagtaaagtgctactgtgaaaaaagctgcattttactgaagtatttctcacttgatattccaaatgtgatcagttccctgttttgaattcatatattttctgttgtgcaaactgttgtcgtaatgtctatttgcacgcgcttttatcactgttacatgttgtgagacctttaaaagtattttcttcctattttagtgaattttgtgtgaaaatttttatataggtttcaatgcggtgctcaacgttgcttgcaaatatccaataaacg

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