LOCUS       XM_074041445            3605 bp    mRNA    linear   ROD 19-MAY-2025
DEFINITION  PREDICTED: Castor canadensis nuclear factor kappa B subunit 1
            (Nfkb1), transcript variant X2, mRNA.
ACCESSION   XM_074041445
VERSION     XM_074041445.1
DBLINK      BioProject: PRJNA1254772
KEYWORDS    RefSeq.
SOURCE      Castor canadensis (American beaver)
  ORGANISM  Castor canadensis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Castorimorpha; Castoridae; Castor.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_133394) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_047511655.1-RS_2025_05
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 05/09/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3605
                     /organism="Castor canadensis"
                     /mol_type="mRNA"
                     /db_xref="taxon:51338"
                     /chromosome="9"
     gene            1..3605
                     /gene="Nfkb1"
                     /note="nuclear factor kappa B subunit 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 17 Proteins, and 99% coverage of the annotated genomic
                     feature by RNAseq alignments, including 36 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:109682963"
     CDS             7..2925
                     /gene="Nfkb1"
                     /codon_start=1
                     /product="nuclear factor NF-kappa-B p105 subunit isoform
                     X2"
                     /protein_id="XP_073897546.1"
                     /db_xref="GeneID:109682963"
                     /translation="

MKVMSNRFKYSSFQIFHLNALPHTIFKAELFPPDMPLSTDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTDACVRGYNPGLLVHPELGYLQAEGGGDRQLTDQEKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGAGGSTGNPGPGYGFPHYGFPTYGGITFHPGTTKSNAGMKHGIINTECENDPEGYDNSDDRETVNLSGKESKPTEQDKESGKSSSGNEVTLTYRVGVKEENACRFQDNLFLEKAMQLAKRHANALFDYAVTGDVKVLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLLEVTSGLVSDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRSGADLSLLDRLGNSVLHLAAKEGHDTILSIVLKHRKAALLIDHPNGEGLNAIHIAVMSNSLPCLLLLVASGADVNARERKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTKLAALLKAAGADPLVENFEPLYDLDDPWENAGEDEGVVPGTTPLDMAANWQVFDILNGKPYEPEFTPDEQGDMKQLNEDAKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTIKELVEALRQMGYTEAIEVIQAAFCTSGTTVSSPKKNTSQAHLLPHSPSTRQHIDELQDSDSICDSGVETSFRKLSFTESLTGSSSLITLNKMPHNYGQEGPIEGKI"

     polyA_site      3605
                     /gene="Nfkb1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

aatgttatgaaagtcatgagtaacagatttaaatattcatcttttcagatatttcacttgaatgcattgccccatacaatatttaaagcagaattatttccaccagatatgccactgtcaacagatggcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttatgtatgtgaaggcccatcacatggtgggcttcctggtgcatctagtgaaaagaacaagaagtcctatcctcaggtcaaaatctgcaactatgtgggacctgcaaaagttattgttcagttggtcaccaatggaaaaaatatccacttgcatgcccacagcctggtgggaaaacactgtgaggacgggatctgcactgtgactgctggacccaaggacatggtggtcggctttgcaaatttgggaatacttcatgtgacgaagaaaaaagtctttgaaacactggaggcacgaatgacggatgcatgtgtaaggggctataatcctggactgttggtgcaccctgaacttggctatctgcaggcagaaggtggaggggaccgacaactcacagatcaagaaaaggagcttatccggcaagcagcgctgcagcagacaaaggagatggatctcagcgtggtgcgcctcatgttcacggcttttctccctgacagcactgggagcttcacaaggcgtctggaacccgtggtatcagacgccatctatgacagcaaagcccccaatgcatccaacttgaaaattgtaagaatggacaggacagcaggatgtgtaactggaggggaagaaatttatcttctctgtgacaaagttcagaaggatgacatccagattcgattttatgaagaggaggaaaacggtggagtttgggagggatttggagatttttctcccacagatgtccatagacaatttgccattgtcttcaaaactccaaagtataaggatgtcaacattacgaaaccagcttctgtgtttgtccaacttcggaggaaatctgatttggaaactagcgaaccaaaaccttttctctactacccggaaatcaaagataaagaggaagtgcagaggaagcggcagaagctcatgcccaacttttcggatagtttcggtggtggcagtggtgcgggagctggaggcggaggcatgtttggtagtggcggtgcaggagggagtactggaaatccaggtccagggtatggctttccacactatggatttcctacatatggtgggattaccttccatcctggaaccactaaatccaatgctgggatgaagcatggaatcataaacactgaatgtgaaaatgaccctgaaggttatgacaacagtgatgacagagagactgtaaatctctctgggaaagaaagcaaacccacagaacaagataaggagtcgggcaagtccagcagcgggaatgaggttactctgacgtacagggtgggagtaaaggaagagaatgcttgtaggtttcaggataacctcttcctagagaaggccatgcagctcgccaaacgtcacgccaatgccctttttgactatgcagtaacgggagatgtgaaggtgctgctggctgtccagcgccatctcactgcagtgcaggatgagaatggagacagtgtcttacacttagccatcatccaccttcatgctcagcttgtgagagatctgctagaagtcacatctggtttggtttctgatgacattatcaacatgagaaacgatctgtaccagacacccttacacttggcagtgatcactaagcaggaagatgtggtggaggacttgctgaggtctggggccgacctgagccttctggaccgtttgggtaactctgttttgcacctagctgccaaagaaggacatgatacaattctcagtatcgtactcaaacacagaaaggcagcactacttattgaccaccccaatggggaaggtctgaatgccatacacatagccgtgatgagcaatagtctgccatgtctgctgctgctggtggcctctggggcagatgtcaatgctcgggagcggaagtctgggcgcacggcactgcacctggctgtggaacatgacaacatttctttggcgggctgcctactcctggagggtgatgcccatgtggacagtaccacctatgatggaactacacccttacatattgcagctgggagagggtccaccaaactggcagcgcttctcaaagcagcaggagcagatcccttggtagagaactttgagcctctgtatgacctagatgacccatgggagaatgctggagaggatgagggagtggtgcctggaaccacacctctggatatggctgccaactggcaggtgtttgacatattaaatgggaaaccatatgagccagagttcacacctgatgaacaaggagatatgaaacagcttaacgaagatgcaaagctacaactctacaagttgctagaaattcctgatccagacaaaaactgggctactctggcacagaaattaggtctggggatacttaataatgcctttcggctgagtcctgctccttctaaaactcttatggataactatgaggtctctgggggaactatcaaagagctggtggaggccttgcgacagatgggctacactgaggcaattgaagtgatccaggcagccttctgcacctcaggaaccacagtgtccagccccaagaagaacacctctcaggctcacttgctgccccactcaccttccacaaggcagcacatagatgagcttcaagacagtgacagcatctgtgacagtggtgtggagacatccttccgcaaactcagctttacagagtctctgactggcagcagctcattgataactctgaacaaaatgccccacaattacgggcaggaaggaccaatagaaggcaaaatttagcctacagacgatttccctcaccagtaaaccaaaaccctaaaattccagtgcatcgtcccaaagaaggaaggtaaagtgcatccagaggtgctcagaggagaaccagcctgccgggatcattctggatttccttccaggccttctaaacttggcttcctttcttggttcttacatgaattttagttggtccacgtacagatagtatatagcaatcacagcactcggggtgagctgacatgtcgctgggggtgacgggtttattgagctttaccggctgctgctggattacagctgcttcctgttgtccttgctgctgtccctctgctgccgtcccaatgtccccacctggtgatctttctagccgccatggcacaatgttcattcagattaaggattaagaaaagagatattttaaaatgagagtcacttgatatgcaataaaaaggcttattgctttttctaatgtgcttctctgtgatttgaaaaaaaaaaacccatgaacttattaatatttaaacatggctgcaatcagtgccgaaaatagtattttcccctttttctgcattttgctattgtaaatatgttttttagatcaaatactttaaaagaaaaaaaatgttggatataaaatgctattttttattttacttttataataaaaggaaaagcaaattgttgaa

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