LOCUS       XM_072319792            4257 bp    mRNA    linear   INV 19-MAR-2025
DEFINITION  PREDICTED: Diadema setosum protein argonaute-2-like (LOC140239984),
            mRNA.
ACCESSION   XM_072319792
VERSION     XM_072319792.1
DBLINK      BioProject: PRJNA1234140
KEYWORDS    RefSeq.
SOURCE      Diadema setosum
  ORGANISM  Diadema setosum
            Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa;
            Echinoidea; Euechinoidea; Acroechinoidea; Diadematoida;
            Diadematidae; Diadema.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_092700) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_964275005.1-RS_2025_03
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 03/17/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4257
                     /organism="Diadema setosum"
                     /mol_type="mRNA"
                     /db_xref="taxon:31175"
                     /chromosome="16"
     gene            1..4257
                     /gene="LOC140239984"
                     /note="protein argonaute-2-like; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 16
                     Proteins"
                     /db_xref="GeneID:140239984"
     CDS             84..2876
                     /gene="LOC140239984"
                     /codon_start=1
                     /product="protein argonaute-2-like"
                     /protein_id="XP_072175893.1"
                     /db_xref="GeneID:140239984"
                     /translation="

MYQPPPHPNLPYGVAQFPQAPIQRPQSGQPPRQQVLPPPIQPQQTTLPPMPPVPGVPAVPQGVPPAPTAGAPPKSELVALPTRPGFGEDGRPIVLRANHFQVKIPGIEIFHYDVTITPDKCPRRVNRDVIDTLVNAYKARYFQHNLPVFDGRRNMYCKEQLPLEHERVELEATLPGEGKDRVFKTQIRYVGKVSLALLESALKGEIEHMPYDAIQALDVIMRHLPSMRYTPVGRSFFSPPDEYFHPLGGGREVWFGFHQSIRPSMWKMMLNIDVSATAFYNAQSVIDFLCEVLDIQNISEHRRALSDSQRVKFTKEIKGLKIEITHCGNMRRKYRVCNVTKRPAQSQTFPWQLENGQTVECTVAKYFKERHNRILQYPHLPCLQVGQEQRHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREKEIKNLVHKANFNNDRYVRQFGLSISNDMVTIEGRVLPAPKIQYGGKQNKTQAIPAQGVWDMRGKQFHTGVEIRVWAIACFAPQHQCREEALRTFTAQLQKISNDAGMPIMGQPCFCKYAVGADQVEPMFRHLKSTYKGLQLIVVVLPGKTPVYAEVKRVGDTLLGIATQCVQVKNVNKTTAQTLSNLCLKINVKLGGINNILVPNIRPRVFAEPVIFLGADVTHPPAGDDKKPSIAAVVGSMDGHPSRYCASVRVQNHRVEIIQDLMGMVRELLMEFYRSTHFKPARIIMYRDGVSEGQFLQVLAQEMTAIRNACRSLEDFYEPGITFIVVQKRHHTRLFCAERREQIGRSGNIPAGTTVDSGITHPLEFDFFLCSHAGIQGTSRPSHYHVLWDDNRFKADELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDRYDHDSHQSGTNSNGGDGSSHHGSSSYSRSFEDMIRAVKVHDDTLKVMYFA"

     misc_feature    <93..>221
                     /gene="LOC140239984"
                     /note="Atrophin-1 family; Region: Atrophin-1; pfam03154"
                     /db_xref="CDD:460830"
     misc_feature    354..746
                     /gene="LOC140239984"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    774..923
                     /gene="LOC140239984"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    927..1289
                     /gene="LOC140239984"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1083..1085,1128..1130,1170..1172,1182..1184,
                     1236..1238,1257..1259,1263..1265)
                     /gene="LOC140239984"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1425..2702
                     /gene="LOC140239984"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1836..1838,1848..1850,1884..1895,1902..1904,
                     1926..1928,1935..1937,1947..1949,1959..1961)
                     /gene="LOC140239984"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2040..2042,2046..2048,2256..2258,2670..2672)
                     /gene="LOC140239984"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gaaagattctacgattcgggaaacgtaccgcggagtttgtcaaaaatatgggccttagatagatgaggaactgaaatcttaagatgtatcaacctccgccccatccgaatttgccgtatggggtggcccagtttccccaggcccccatccagcggccccagtccggccaaccccctcgccagcaagtcttgccgccccccatccagccccagcagaccacccttccaccgatgccaccggtcccaggggtacccgcggtgccccagggggttcctcccgctccgaccgcgggcgctcccccaaagtcggaactcgttgccctgccgacgcggccgggctttggagaggacggccgacccatcgtcctgagggccaatcacttccaggtcaagattccggggatcgagatctttcactatgacgtgaccatcactccagacaaatgtcctcgcagagtcaacagggatgtgattgacactctggttaatgcctacaaggctcgctacttccagcacaacctaccggtcttcgacgggcggagaaacatgtactgcaaggaacagctccctcttgagcacgaaagggtggagctcgaagcgaccttgccaggagaaggcaaggaccgggtgttcaagacccagatccgctacgtggggaaggtcagcctggccctgctggagtctgccctcaagggagagatagagcacatgccgtacgacgccatccaggcccttgacgtcatcatgaggcatctaccatcaatgaggtacaccccagtgggtcgttccttcttctccccgccggacgagtatttccaccccctgggagggggcagggaggtgtggtttggtttccaccagagcattcgcccctccatgtggaagatgatgctcaacattgatgtctcagccacagccttctacaatgcccagtcagtgatcgactttctgtgcgaggttctagacatccagaacatatcagagcatcggcgcgccctgtccgactcgcagagagtcaaattcaccaaagaaatcaaaggcttgaagattgaaataactcactgcggtaacatgagaaggaaatatcgggtgtgcaatgtgacaaagcgaccggctcaatcacaaacattcccatggcaactggagaatgggcagactgtggagtgcaccgttgccaagtacttcaaggagaggcataaccgaattttgcaataccctcaccttccctgtctgcaggttggacaggagcagcgccacacatacctacctctggaggtttgcaacattgtagccgggcaacgctgtatcaagaagctgactgacatgcaaacctccaccatgatcaaggcaactgcaagatcggccccagatagggaaaaggaaataaaaaacttggtgcacaaagcaaacttcaataatgaccgctacgtcagacagtttggcctcagcatcagcaacgacatggtcactattgagggaagagtgctgcccgctcccaagatccagtatgggggaaagcaaaacaagactcaggccatccccgcccagggcgtgtgggacatgaggggcaagcagttccacactggtgtcgagatccgagtctgggccatcgcctgcttcgcaccacagcaccagtgccgggaagaagccctcaggacattcacagcccagctccagaagatctccaacgatgcggggatgccaatcatgggccagccgtgcttctgcaagtacgccgttggcgctgaccaggtggagccgatgttcagacacctcaaatccacctacaaggggttgcagctcatcgtagtggtactgccgggcaagacacctgtatatgccgaggtgaagcgggttggcgacacgctgctgggaatcgccacccagtgcgtccaggtcaagaatgtcaacaagacgacagcgcagaccctctccaacctctgcctgaagatcaacgtcaagcttggtggcatcaacaatatcctggtgcctaacatcaggccaagggtctttgccgagccagtcatcttcctcggtgccgatgtcacccacccaccggcaggggatgacaagaagccatccattgctgcagtggtggggagcatggacggccatcccagccggtactgcgccagcgtgcgggtccagaaccaccgggtggagatcatccaggacctgatgggaatggtgagggaactgctgatggaattctaccgctccacacacttcaagccggccaggatcatcatgtaccgtgatggtgtcagcgagggacagtttcttcaggtgctagcccaggagatgacggcgattcgcaatgcctgccggtccctggaagacttctacgagccgggcatcaccttcatcgtggtgcagaagagacatcacaccagactcttctgtgcagagaggagggaacagatcgggagaagtggtaacatccctgctggtacgacagtggacagcggcatcacgcaccccctcgagttcgattttttcctttgcagtcatgctggcattcagggcacgagtcgaccctcccactaccacgtcctgtgggacgacaaccgctttaaggcggacgagctccagtgtctgacctaccagctgtgccacacctacgtccgctgcacccgaagcgtctccatccccgcccctgcctactacgcccacctcgtggccttccgcgcccgctaccacctcgtggagaaggaacacgaccgctacgaccatgacagccatcagtccggtactaacagcaatggtggggacggaagcagtcaccacggctcgtccagctacagccgaagcttcgaggacatgattcgggcggtcaaagttcacgacgacacactgaaggtcatgtactttgcatagagggcgtcgtcagcaggtgtctctcaaatgttttccaagacataaatgttcaaaaaagagaatctacaggtcagtgacacgttgacaaggagattgggtcaaagggtgaaaggtcaggggctgtgtgtttacagccatctgaaatgtatgacacacacacactcacacatatgatttatgtagaggtttcactgaaatgagtggcaactgaatgttcaataaagtatgtgcaggtcagtgacatattgacatggagattggggcaaagggtgaaaggtcaggggcttgtgttgatagccatctgaagtgtacgacacacacacactcatacatggtttatgtagaggtttcactgaaatgagtggcgactgaatgttcaataaagtatgtgcaggtcagtgacatattgacatggagattgggtcaaagggtgaaaggtcaggggcttgtgttttatacagccatctgaaatggatggcacacacacgcattcacacatgatgtatgtcgaggtttcactgaaatgagtggtgactgaatgttcaaaaaagtatctgcaggtcagtgacatgttgacatggcgattgggtcaaagggtgaaaggtcaagggcttgtgctcacagtcatctgaaatgaacgacacacacactcacctttggtgtatgtagaggtttcactgaaatgaggggagactgaaagttagtgtgtgacccaggtgcttatctgtcgaccgaaatgacaaccagtaacctcagcttgcctatcttacacatctcatgaggtcaggggtcatcaccactttgttgccatggtgaggagattcctttgtttgtttgtttaggttatttttaacattcatctaacattcattgcaaaacgaataagtcttttatcaagaaacacagtagactgctggtaggtctcacattatttgtacgaaatcaattttatggacagaacaatttcttattactgatacttattgtttctcagtttcttgtttgtgtgggttatttttacatgaactcttgctatttttcctgtcgaatatatcataaaattgatcatttccatgtaatcatgtaagaaaatcattttatcgcgtctgctcattttcagtcactactccgatgagacactgtgcatctaagttgttaagtcttttgatttttagcatggatcttacataactatgtagatatcacttgtgaaatgtagattgttgggttttgtactgaagacatgtttagaagaaggcaatattatgtggtattgagccaataaaatggggcaggtaattttttggaaagagtacttaaggggcatcagaggatattggcattgtaaaaattcaatttaatacaactttcatgcaaggag

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