LOCUS       XM_059128476            2577 bp    mRNA    linear   INV 24-AUG-2023
DEFINITION  PREDICTED: Musca domestica protein argonaute-2-like (LOC131805362),
            mRNA.
ACCESSION   XM_059128476
VERSION     XM_059128476.1
DBLINK      BioProject: PRJNA1002374
KEYWORDS    RefSeq.
SOURCE      Musca domestica (house fly)
  ORGANISM  Musca domestica
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Musca.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_026712121) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030504385.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/18/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2577
                     /organism="Musca domestica"
                     /mol_type="mRNA"
                     /strain="aabys"
                     /db_xref="taxon:7370"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="Whole body"
                     /dev_stage="adult"
     gene            1..2577
                     /gene="LOC131805362"
                     /note="protein argonaute-2-like; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 12
                     Proteins"
                     /db_xref="GeneID:131805362"
     CDS             172..2577
                     /gene="LOC131805362"
                     /codon_start=1
                     /product="protein argonaute-2-like"
                     /protein_id="XP_058984459.1"
                     /db_xref="GeneID:131805362"
                     /translation="

MKQQKGQVGVSAVMGKKNSGQTSCTGIVRGTRGTPGTVEVNYLKLLLDSMPNKVYHYDITITPVRSKQFVRLAFQKCKQKYFHDIEAAFDGKKSCYTPKRLSSPINGTVKVSDSNSRTIEFQVEIKETLDCEVDLNSLRTYHNDSVSDKPMRALQALYVILSESNHEKGLRVGRAFFCKPIKPHDLGDGYEAWTGLFEAVILGDQPFLNVDITHKSFPSESSLIDYLKNQKIGLDRDLRENKQVQSYLRGINIVYQPPESFKSFARKYKVLKIGNSASQLHFLNGDGLQMTVAEYFKSRGYSLKYPNLSCVEVGSTAHSIYLPMELCKIAGGQVLNRKDESTQVRNMIRFAATSTNVRKRKIMDMLQHFNLNASKIVQSFGIKIDLNFIKVPIRVLPSPIIEYLNGQTVNVKRGGWMMDKQQFLICTKPQAGKQVGHKWAIIYQSGIEYIHLDNFKKSVLKKAKDLNMHLENAAEIMKYTDIYSTLLNLAKSDYALVFVVLGRTAYYHIKQVADLKVGVLTQCIQDKTVKKIAQSPAIISNLLLGVNGKLNGTNHKILLNNADDMKELMAPIKNVMFMGADVTHPSPDQPHIPSVVGVTASHDRIGACYNMQYRLQQSTKEDIEDMESITNRHLEFYFQFMKTYPTHIIYYRDGVSDGQFPIIQRVELSAIQRACRKKGCDTKLTCIIAVKRHHTRFFPMKQQRDERDLNNVEPGTVVDQMITHPREVQFFMVSHQSIQSTAKPTRYNVILNESNFDIDLLQQLTYNLCHLFPRCNRSVSYPAPVYLAHVAAFRARVYLEG"

     misc_feature    439..654
                     /gene="LOC131805362"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    835..1161
                     /gene="LOC131805362"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(973..975,1015..1017,1045..1047,1057..1059,
                     1108..1110,1129..1131,1135..1137)
                     /gene="LOC131805362"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1294..2568
                     /gene="LOC131805362"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1687..1689,1699..1701,1735..1746,1753..1755,
                     1783..1785,1792..1794,1804..1806,1816..1818)
                     /gene="LOC131805362"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1912..1914,1918..1920,2128..2130,2536..2538)
                     /gene="LOC131805362"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gaacaaagaagaaaagacaaccagcagggtacagaaaataaacaacaaggtggacagccaaagcaacaacgaaatccagcacaactacaaaggggacaggcacaacaacaaggagaaaaagatcaaaatgtcaaaaatatcagtgtgcagcgctcacagcaaggaaggcagatgaagcagcaaaaaggacaagtgggggtttcagcagtcatgggaaaaaagaacagtggacagacatcctgtactggcattgttcgtggcacacgtggtacaccaggtactgtagaagttaactatttgaaattgttacttgatagtatgcccaacaaggtctatcactacgacattacaataactcctgtccgttcaaaacaatttgtaagacttgcttttcagaagtgtaaacaaaaatatttccatgatattgaggccgcttttgacggaaaaaagagttgctatacaccaaaacgtctttctagtccaatcaacggcacagttaaggtttcagactcaaacagccgcaccatagaattccaagtggagataaaggaaaccctggattgcgaggtggatctaaattcacttcggacataccacaatgattcagtgtccgacaaaccaatgagggccttgcaagcattgtatgttattttgtctgaaagtaatcacgaaaagggcctacgcgtcggtcgagcatttttttgcaaacccataaaaccacacgatttaggggatggttacgaagcttggactggtttgtttgaggctgtaattttaggcgatcagcccttcctaaatgtcgacatcacccacaaatcatttcctagtgagtctagcctgatcgattacttgaaaaatcagaaaatcggattagaccgagatttaagggagaacaaacaagtacagagttatcttagaggcattaatattgtgtatcaaccaccagaatcatttaaaagttttgccaggaaatacaaagtattgaaaatagggaattctgcttcccagctacatttcttaaatggtgatggtctacaaatgacggttgctgaatactttaaatctcggggatactcacttaagtatccgaatttaagttgtgttgaagtcggttcgacggctcattcgatatatttgccaatggaactatgtaagattgcagggggccaggtcttgaaccgtaaagacgaatcaacacaagtacggaacatgatacgttttgctgcaacttctactaatgttcgcaagagaaaaatcatggatatgctgcagcatttcaatcttaatgccagcaaaatcgtccaatcatttggtattaaaattgatttgaattttattaaagtgccaattcgagttttaccaagcccgattatcgaatatttgaacggtcaaactgttaatgtaaaacgcggtggttggatgatggacaagcaacaattcttgatttgtactaaaccgcaagcaggcaagcaggttggacacaaatgggcaataatatatcaatcaggaattgaatacatacatctggataattttaagaaatctgtcttaaaaaaggcaaaggatttaaacatgcatcttgaaaatgcggctgaaattatgaaatatacggatatttatagcactcttctgaatctggctaagagtgactatgctttagtctttgttgtcttaggcagaaccgcttattaccatattaagcaggttgctgatttaaaagtaggagttttaacgcagtgcatacaagacaaaactgttaaaaaaattgcgcaatctccagcaattatctcgaacctccttttgggggtaaacggaaagcttaacggaaccaaccacaagatattactgaacaatgctgatgacatgaaagagttaatggctcccattaaaaatgtgatgttcatgggtgctgatgtgacgcatccctctcccgatcagccccacattcctagcgtagtgggagttacggcttcacacgatcgaattggagcatgctataacatgcaatacagattgcaacaatctactaaggaagacattgaagatatggagtcgatcacgaatcggcatttggagttctatttccagtttatgaaaacgtatcctactcatattatctactatagagatggcgtctcggatggtcaatttcccattatacagagggttgaattgagtgcaatacagagggcttgtcgaaaaaagggatgtgatacaaaattgacctgcatcatcgcagttaagcggcatcacactcgattcttcccaatgaagcaacagcgcgatgaacgcgacttaaataatgttgaacctggtactgttgtcgaccagatgataacacaccctagagaagttcaattttttatggttagtcaccaatcgattcaaagcaccgccaaaccaactcgctataatgttattttaaatgaatcgaacttcgatattgatctcttgcaacaattaacctataatttgtgtcatttattcccacgttgcaaccgatctgtttcctatccggctccagtttatctggcgcatgtggccgcatttcgtgctcgggtttatttagaagggtga

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