2024-09-08 11:44:26, GGRNA.v2 : RefSeq release 225 (Jul, 2024)
LOCUS XM_056122744 6235 bp mRNA linear MAM 09-OCT-2023 DEFINITION PREDICTED: Sorex fumeus argonaute RISC component 4 (AGO4), transcript variant X3, mRNA. ACCESSION XM_056122744 VERSION XM_056122744.1 DBLINK BioProject: PRJNA972655 KEYWORDS RefSeq. SOURCE Sorex fumeus (smoky shrew) ORGANISM Sorex fumeus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Soricidae; Soricinae; Sorex. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_026606104) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_029834395.1-RS_2023_10 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.2 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 10/04/2023 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..6235 /organism="Sorex fumeus" /mol_type="mRNA" /db_xref="taxon:62283" /chromosome="Unknown" gene 1..6235 /gene="AGO4" /note="argonaute RISC component 4; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 5 Proteins" /db_xref="GeneID:130031409" CDS 36..2420 /gene="AGO4" /codon_start=1 /product="protein argonaute-4 isoform X2" /protein_id="XP_055978719.1" /db_xref="GeneID:130031409" /translation="
MVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA"
misc_feature 45..299 /gene="AGO4" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 330..482 /gene="AGO4" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 483..845 /gene="AGO4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(639..641,684..686,726..728,738..740,792..794, 813..815,819..821) /gene="AGO4" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_feature 984..2291 /gene="AGO4" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the...; Region: Piwi_ago-like; cd04657" /db_xref="CDD:240015" misc_feature order(1395..1397,1407..1409,1443..1454,1461..1463, 1485..1487,1494..1496,1506..1508,1518..1520) /gene="AGO4" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240015" misc_feature order(1599..1601,1605..1607,1845..1847,2259..2261) /gene="AGO4" /note="active site" /db_xref="CDD:240015" ORIGIN
aagcggcctcgtagagtcaacaggtagtagatacaatggtgcgacacttcaagatgcaaatatttggtgaccggcagcctggctatgatggcaaaagaaacatgtacacagcacatccactgccaattggacgagatagggttgatatggaagtgacccttccaggtgagggtaaggaccagacctttaaagtgtctgttcagtgggtgtcagttgtaagccttcagttgctgttagaagccttggccggacacttgaatgaggtgccagatgattcggtacaagcccttgatgtcatcacaagacaccttccctccatgaggtatactccagtgggccgttcctttttctcacctcctgaaggttactaccaccctctgggagggggcagggaagtttggtttggttttcatcagtctgtgagacctgccatgtggaatatgatgcttaacattgatgtatctgcaactgctttctaccgggctcaacctatcattgaattcatgtgtgaagttttagatattcagaatatcaatgagcagaccaaacctctaaccgactcccagcgtgtcaagtttaccaaagaaatcagaggtcttaaagttgaggtgactcactgtggacagatgaaacgcaaatatcgagtttgtaatgtcactagacggccagccagtcatcaaacttttcccttgcagctagaaaatggtcaagctatggaatgtacagtagctcaatactttaagcaaaagtatagtttgcagctgaaatatccccatcttccctgtctccaagtgggacaagaacaaaagcatacatacttgccacttgaggtctgtaatatagtggcaggacagcgatgtattaagaagcttacagacaatcagacttccacgatgatcaaagccacagcaaggtctgctcctgacagacaggaagaaatcagtagactggtgaagagtaacagcatggtgggtggacctgatccataccttaaagaatttggtatcgttgtgcacaatgaaatgacagagctcacaggcagggtacttcctgctccaatgctgcaatatggaggccggaataaaacagtagccactcccaaccagggtgtctgggacatgcgaggaaagcagttttatgctggcattgaaattaaagtctgggcagttgcttgttttgcacctcagaaacaatgtagagaagatttacttaagagttttactgaccagcttcgtaaaatctctaaggatgcaggcatgcctatccaaggtcaaccatgtttctgcaagtatgcacaaggtgcagacagcgtggagcccatgtttaaacatctgaaaatgacatacgtgggcctacagttaatcgtggttatcttgcctggaaagacaccggtatatgcggaggtgaaacgagttggagataccctcctgggaatggccacacagtgtgtccaggtgaaaaatgttgtgaagacctcaccccaaaccctttccaacctttgcctgaagataaatgcaaagcttggaggaatcaacaatgtgcttgtacctcatcaaaggccctcagtgttccagcagcctgtcatctttctgggcgcggatgtcacacaccctccagcaggcgatgggaagaaaccctccattgctgctgtggttggcagtatggatggccaccccagccggtactgtgccactgttcgagtgcagacctcccgccaagagatttcccaggagcttctctatagccaggaggtaatccaggaccttactaacatggttcgagagttgctgatccagttctataaatctacacgtttcaaacccacgcggatcatctattaccgtggaggagtatcggagggacaaatgaaacaggtagcttggccagaactaatagcaatccgaaaggcatgcattagcttggaagaagattaccggccaggaataacctatattgtggtacagaaaagacatcacacacgactcttctgtgcagacaaaacagaaagggtggggaaaagtggcaacgtcccagcaggcactactgtggatagcaccatcacacatccatctgagtttgacttttacctctgtagtcatgcaggaattcagggaaccagccgtccttcgcattaccaggtcctgtgggatgataactgcttcactgcagatgagctccagctattaacttaccaactgtgccacacctatgtgcggtgcacacgctcagtctctattccagcccctgcatattatgcccgacttgtagcattcagagcaagatatcatctagtggataaagatcatgacagtgctgaaggcagtcatgtgtcaggacagagcaatggccgagatcctcaggccttggcgaaggctgtgcagatccaccatgatacccagcacacaatgtattttgcctgagagtgtcagaaaaagaactcaaccagcttggcaccccattcagcctcataatgtttcaaatgcctaccgcctctagagagccaagttgacttcaggtggtcttctaccagcagcttggaatagttgcactgattctattcttcatagcactgtctaatgcatcaacaaaatcgagccatttaaaaaaaaagaaaaagtaatagatactcatagattgtcttttctgatgcactggactgaatttttacctcatcatacaaaggctgatcagcctgaactgtctaaaggactttacaagaaaggtttctatggaatattttgctagctgtggtgttcaccgcatccctctagtcttataaaagaagattattccttttttctgtattcattttgtggggtatatgcgtaagtgggagagaaaaaccaaacaatttacttcagttcagcgtaactatttaattgtgtgggtacacagactttttaatggagatttctgactctgccactgtaaatgcctttaacgagcattaatttttttaaatttttacagagttttattagttttactactttatcttataactgactacagacttgtgctagtgcaagtcaggctgccaggcaatcacactgtatttggctgtagattcatatgggcagttctgttatttggttgacttctgtgaatgtgtaacacaagcagatgtaatgcatatcatggtggccggtaacactgccatggcaaaaagcactcatacttcccccactttgagaaaaaaatattagcttttagtatttttcaaagttttcaaaagtgcccattttatgctgctgtgtggtttgttagatctaaatgacttttaaacttttctcatagaaaattaacgttggcaataaacattttttaaggtcccatctcttcctccccaacaatgtagttttctagatgagattttggtatgattttatcagctctttcttattgatcataatctggcaatttctgatactggtcagataagacatatatttccatgctttttaaaagaattatttttatctgttttatagtcacaattggtgtcctgtcattttgttttaaaataagctagaaccaggatgcaattggatgggctttgccgatccttaaggtacattgagtgatgctgcaacttgcaaaaatgtaccagcatttaaaacttctttgcctggggatcaaggttacccacagaattacttgcagtgtacattttttcttccccttctctatgaaatgtacttagtggggtttccttccttttataaaattaaaactgcaagaaaagattaatttctctttaaaagattctgaatcctcttcataaggagacaggattcctttcttatccaaacaaaggaggttgatctgaagcaagcatcagctgaaatgtaaggggaaatgtattttgtatttagtgtagataatactttgtgaatggacagcagttacatagaatcttggtagttccagccagtgtttcccagccccagttttactgacttgtggttcactagcctagatcctcaggagtgagagctaagaaaggggcagaaaaatcccagagaagccacactccataggactgaggaaggtgctggggaagacgcagacgcagagcggtaaatgactttgccgcctctgtctggaaaccactggtaggggaacactggatctggtggtgaagggtgcttgcatatactcattagccagtccaaatctcttcaactagccttctcaaaatcccagcaatataaaacattgtttttcttcagtcttttaaataagcttgtaaatacattgaagtttacatttccacgtgctgttgatcagcggcgccaccagtgtttgctgaaactggtctcttgagggttttataatgtatatcgagtcctatagctcagtaagatggctgcagatatcattattctctgcgtatagggggtgaaagcaagctctgtgattgaggcacaaaataggtaggagtgaagaaatggcaatgttaatttttaagattttccttttttttttttttggcaaatacctcacttggataatacaaatcaggacatgttggtgaggggctggctgctgcttttattcacacttgttcagggagagcacagaaaatgcccttcagcatggccaccctgaacccaagaggaggacacagatccttttttcttcttcttcttctttttttttcttttttaggagcaggaggactctcaggggtccaggatatgaagaattcttggtggctggctggctggctggctggctggccagcaagccccacacttgtacttgagtgcctctggtttatgaataaggcacagagcacaaaggagcatcgcttcttaccctctccttgcctgtatggagcagagagtgaggcagagtaccagaaagccctgatcacttgcctgcagttgactatatgctcgaccttgaactatgtacagttcgtatgacttagtcagtcctagtacactggagagaatcagtgtggtggtggaggaaatgccgggaggcctattttttttttttaaatgcaggaaaacagcacctttaagggtgcaatgctgtcgtttagagtgaaaagaaagaaatccagaagaacaaggattattagaaaaaaacttgctgagggttgaattttaagaggtaattgctgcagaatccgagttacagcaatacacttgcaagcaagactgaatgggcagttttcatgtaattgggcctgactcgggactgactgaattgttatgcatgtgtcaatcaatgggaggtgtgcatctctagaagtagtttttggctgtttgatttttttaaatgcagcctgtttaggcactgttatgtggtgtgaaagatttaaatgtagcaatgcgaaagagtaacaatttgggaataagagttgggggcttatgaagagagtggcaaagacccaaactttgaaccaattatgttttactgttgttagctgttgacttctgaatggtttgtaatggcttcatgcagccagcagtctgggcaggcagaacacgttaattcttactgtaaattctatttgctgcttccaaaggtgatgatttacaagcagacatattccatatgatctgtaccttaggatctggtgcccagcctatttaccagagcttatctacctgcttcagctacctgccctcatgggaaaggtaattaattcactgtttcacaaggctcactctctctttccagccctcgtgaccctttgtggatgtgctgtctgactcttgctcaatagcaaagtggtagctctgctttcattttaagaaagtggaggttgagggcattgtatcaatactgcttcagttccaaggatttttcctcataaaattaaagggaagatcttactgatcaaccatttccttgtcccttgctattgacatattcatgctctttctgtgtctagtggctgaaaatgtttgcatttgttcacttgactaatggtgtaatttttgtttctatattgttagacttgtaatgttttaaaaatgtattttattaaatttgaactggatgtatgtctctagcaatacgaggtactttctaaactattaagggaggggtggtattcccatgttgagataaaaggatggttgtttaaattttacaaattttttggcctgcagggatattttgtgttcatgtgtcaaaaaaaaaaagaaaaaaagaataaattggcatttgtgtgccaaaagttgtttttcttgtcaattgtctaataaatatggag
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@meso_cacase at
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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