2024-09-08 11:44:01, GGRNA.v2 : RefSeq release 225 (Jul, 2024)
LOCUS XM_056110923 3877 bp mRNA linear MAM 09-OCT-2023 DEFINITION PREDICTED: Sorex fumeus argonaute RISC catalytic component 2 (AGO2), mRNA. ACCESSION XM_056110923 VERSION XM_056110923.1 DBLINK BioProject: PRJNA972655 KEYWORDS RefSeq. SOURCE Sorex fumeus (smoky shrew) ORGANISM Sorex fumeus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Soricidae; Soricinae; Sorex. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_026606068) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_029834395.1-RS_2023_10 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.2 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 10/04/2023 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3877 /organism="Sorex fumeus" /mol_type="mRNA" /db_xref="taxon:62283" /chromosome="Unknown" gene 1..3877 /gene="AGO2" /note="argonaute RISC catalytic component 2; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 26 Proteins" /db_xref="GeneID:130020313" CDS 150..2729 /gene="AGO2" /codon_start=1 /product="protein argonaute-2" /protein_id="XP_055966898.1" /db_xref="GeneID:130020313" /translation="
MYSGAGPVLTPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"
misc_feature 423..647 /gene="AGO2" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 675..827 /gene="AGO2" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 828..1190 /gene="AGO2" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(984..986,1029..1031,1071..1073,1083..1085, 1137..1139,1158..1160,1164..1166) /gene="AGO2" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_feature 1323..2600 /gene="AGO2" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the...; Region: Piwi_ago-like; cd04657" /db_xref="CDD:240015" misc_feature order(1734..1736,1746..1748,1782..1793,1800..1802, 1824..1826,1833..1835,1845..1847,1857..1859) /gene="AGO2" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240015" misc_feature order(1938..1940,1944..1946,2154..2156,2568..2570) /gene="AGO2" /note="active site" /db_xref="CDD:240015" ORIGIN
cgcccgggccgcgtcgggtaaacctgtttggcgaggcggccgcgccggggcggatcgcgcggcccgggctccctcgcggctcgcggcgtcggggcccctggcgcgcgcacggccgcccctcggccccggagcccctcggcggcgccaccatgtactcgggagccggccccgtgctcacgcctccagcgccgccacctcccatccaaggatatgccttcaagccgccgcccagacccgacttcgggacctccgggagaacaatcaaactgcaggccaacttctttgaaatggacattcccaaaatcgacatctaccattatgaactggatatcaagcctgagaagtgcccaaggagagtgaacagggaaatcgtggagcatatggtccagcactttaaaactcagatcttcggggatcggaagccagtgtttgatggaaggaagaacctctacacggccatgccgctgcccatcggcagagacaaggtggagctggaggtgacgctgccgggggagggcaaggaccgcatcttcaaggtgtccatcaagtgggtgtcctgcgtgagcctgcaggcgctgcacgatgcactttcggggcggctgcccagcgtccctttcgagaccatccaggccctggacgtggtcatgaggcatttgccatccatgaggtacacgcccgtgggccgctccttcttcaccgcctccgaaggctgctccaacccgttgggcgggggccgcgaggtctggttcggcttccaccagtcggtgcggccatccctgtggaagatgatgctcaatatcgacgtctctgccactgcattctacaaggcccagccagtaatcgagtttgtgtgtgaagtcttggattttaaaagtatcgaagagcaacagaaacctctgacagattcccaaagggtgaagtttaccaaagaaatcaaaggcctgaaggtggagatcacacactgtgggcagatgaagaggaagtaccgcgtctgcaacgtgacccggcggcccgccagccaccagacgttcccgctgcagcaggagagtgggcagaccgtggagtgcaccgtggcccagtacttcaaggacagacacaagctggtcctgcgctacccccacctcccgtgtctgcaggtcggccaggagcagaagcacacctacctccctctcgaggtgtgcaacatcgtggctgggcagcgctgcatcaagaagctgacggacaatcagacctcaaccatgatcagggcgaccgcccgctccgcgcccgaccgccaggaggagatcagcaagctgatgcgcagcgccagcttcaacacggacccatacgtgcgtgagtttggaatcatggtcaaggatgagatgaccgacgtgactggccgcgtcctgcagcctccttccatcctctacgggggccggaacaaagcaatcgccacacctgtgcagggggtctgggacatgcgcaacaaacagttccatacaggcatcgagatcaaagtgtgggccatcgcctgctttgcaccccaacgccagtgcacggaggtgcacctcaagtccttcaccgagcagctccggaagatctccagggacgcagggatgcccatccaggggcagccttgcttctgcaagtacgcccagggcgctgacagcgtggagcccatgttccggcacctgaagaacacctatgccggcctgcagctggtggtggtcatcctgccgggcaagacccctgtctacgctgaggtcaagcgcgtgggggacacggtgctgggcatggccacacagtgtgtgcagatgaagaatgtgcagaggaccacaccccagacgctgtccaacctctgcctgaagatcaatgtcaagctgggcggcgtcaacaacatcctgcttccccagggcaggcctccagtgttccagcagcccgtcatcttcctcggggctgatgtcacacacccccctgctggtgatggcaagaaaccctccattgcagctgtcgtgggcagcatggatgcccaccccaaccgctactgtgccactgtgcgggtgcagcagcaccggcaagaaatcatccaggacctggcggccatggtgcgggagctgctcatccagttctacaagtccacacgcttcaagcccacccgcatcatcttctaccgtgatggcgtgtccgagggccagttccagcaggtgctgcaccatgagttgctggccatccgcgaggcgtgcatcaagctggagaaagactaccagccgggcatcaccttcatcgtggtgcagaagaggcaccacacgcggctcttctgcactgacaagaacgagcgggtggggaaaagtgggaacatcccagcaggcaccactgtggacacaaagatcacccaccccaccgagtttgacttctacctgtgcagccacgctggcatccagggaaccagcaggccttcccactaccatgtgctctgggatgacaatcgcttctcttcggacgagctgcagatcctcacctaccagctgtgtcacacctacgtgcgctgcacgcgctcggtgtccatcccagcacccgcctactacgcccacctggtggcctttcgggccaggtaccacctggtggacaaagaacacgatagtgctgaaggaagccatacctccgggcagagcaacggccgagaccatcaggcgctggccaaggccgtgcaggtccaccaggacacgctgcgcaccatgtacttcgcttgactgttgacatgtttacgattgtgcaccagttggattcacatgagaccagctacactcagaccaacagaggcccaccccttccgtgcagcccgcgggaacatgaggcgtcgtcggcttcgctagattcgccatttccagattgccttccgtccccgatttcagacttggatttggaactgcagcctgtgtgagacccactgcctaggaagtatggtttgccaaaatctctaagctgcttgttaacacagagtcccgtgttcccgaacatctcccagaaccagtctatgaactcagggctttaaaacatttttaatttatttggttattcgatgtactcgtttctaacacacgattctctatggaagggatgggctcgaactagccgtgagcactctgagagggagccacccaccgcacgggtggttttaaagccttgagcctcccggttccaagtgaccgagcgtgctccttcccgggctgccccagccccttggccgcccccacccgccctgggcaaagagccaggagcaagcagaggtgggcggtgtgcgtttacactcgtgggcccagagagattggcaggcaagtgccattttggtagagatttatgtaaaacaaaacaaaaaaagagcaaagacagaatgccggcggtctgatcgcgggctcgcctctaggactgtgatgtttattcccaaagtttctgaagaatacgggtctgtgggatggacacagtacaatcctctctcactgcgtgtctgtgacgtgaagaaagtagatacctggtttgcagtattactgggataggtagaaactttttcattttgggactacggggtgcttcttcctgttacctgttcagcgtgtcagagtattagtggggcggggggcggtgccaccccgtggcccccggtgctggcgagcgggagcctgtgtgtctccaggggtgctgcggcccgtacctccctcccagggcgccaccccaccccgccccgtaggacccccacccgacgaagcacaaattgggtgtgctgaccctcccgtcctggaccgggttccgtgaggggcacccctccccggtggaagggtggatgcactgagacagacacggggctgcccgctgtggaagcagttgcaccaagggagcggct
//
by
@meso_cacase at
DBCLS
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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