LOCUS       XM_053823302            2865 bp    mRNA    linear   INV 24-FEB-2023
DEFINITION  PREDICTED: Anopheles nili protein argonaute-2 (LOC128730264),
            transcript variant X1, mRNA.
ACCESSION   XM_053823302
VERSION     XM_053823302.1
DBLINK      BioProject: PRJNA934361
KEYWORDS    RefSeq.
SOURCE      Anopheles nili
  ORGANISM  Anopheles nili
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Nematocera;
            Culicoidea; Culicidae; Anophelinae; Anopheles; nili species
            complex.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_071291) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_943737925.1-RS_2023_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/14/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2865
                     /organism="Anopheles nili"
                     /mol_type="mRNA"
                     /db_xref="taxon:185578"
                     /chromosome="2"
     gene            1..2865
                     /gene="LOC128730264"
                     /note="protein argonaute-2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 79
                     Proteins"
                     /db_xref="GeneID:128730264"
     CDS             1..2865
                     /gene="LOC128730264"
                     /codon_start=1
                     /product="protein argonaute-2 isoform X1"
                     /protein_id="XP_053679277.1"
                     /db_xref="GeneID:128730264"
                     /translation="

MSTERELTPGSTQQLHPLSYSDMATHIQLNGIMGKSFNESPWTSSPPRPPSPSQSQTSFDTLSPPPAGATVNPTTVATTTGTQGSQPLGVVPATPPAPPDLPVFTCPRRPNLGREGRPIVLRANHFQITMPRGFVHHYDINIQPDKCPRKVNREIIETMVHAYSKMFGALKPVFDGRNNLYTRDLLPIGNDRVELEVTLPGEGKDRVFRVTIKWVAQVSLFNLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPDGYYHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGTMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYKMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVRRADFNNDAYVQEFGLTISNNMMEVRGRVLPPPKLQYGGRVSSMSGQLLSGPQNKVSLALPNQGVWDMRGKQFFTGVEIRVWAIACFAPQRTVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKSTFSHLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILVPSIRPKVFDEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIIQELSSMVRELLIMFYKSTGGFKPHRIILYRDGVSEGQFPHVLQHELTAIREACIKLEADYKPGITFIVVQKRHHTRLFCADKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFESDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSEDRTPGAMARAITVHADTKKVMYFA"

     misc_feature    349..738
                     /gene="LOC128730264"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    766..918
                     /gene="LOC128730264"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    919..1281
                     /gene="LOC128730264"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1075..1077,1120..1122,1162..1164,1174..1176,
                     1228..1230,1249..1251,1255..1257)
                     /gene="LOC128730264"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1417..2736
                     /gene="LOC128730264"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1867..1869,1879..1881,1915..1926,1933..1935,
                     1957..1959,1966..1968,1978..1980,1990..1992)
                     /gene="LOC128730264"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2071..2073,2077..2079,2290..2292,2704..2706)
                     /gene="LOC128730264"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

atgtcaacggaaagggaactaactcccggatcgacgcagcaattgcatcctctgtcatactcggatatggccacacatatccaactgaacggaataatgggaaaatcgtttaatgaatcaccatggacttcttcgccgccaaggcctccaagtccgtctcagtcgcagaccagcttcgatacactttcaccaccaccagccggtgcgacggtcaacccgaccacggtggcaacgacaacgggaacccaaggttcccagcctctcggtgttgttccggccacaccaccggcacccccagacctaccggtgttcacatgtccgcgccggcccaacttgggtcgcgaaggacgaccgatcgtgctgcgggcgaaccatttccagatcacgatgccccgtggcttcgtgcatcactacgatattaacatccagccggacaaatgtccccgaaaggtgaaccgcgagatcatcgaaacgatggtgcacgcgtacagcaagatgtttggtgccctgaagcccgtctttgacggacgcaataacttgtacacgcgcgatctgctcccgatcggaaatgatcgcgtcgagctcgaagtgacacttcctggtgagggtaaggatcgtgttttccgcgtcacaatcaaatgggtggcgcaggtgtcgctgttcaacctggaggaagcgctcgaaggacgcaccagacaaatcccgtacgatgcgatccttgcgctggacgtggtgatgcgccatctaccaagcatgacgtacacacctgtcggtagaagcttcttcagttctccagatgggtactatcatcccctcggaggaggtcgtgaggtttggttcggtttccatcaaagcgtccgaccgtcgcagtggaaaatgatgctaaacattgacgtgtcggccaccgcattctacaaagcgcaaccggtgattgagttcatgtgcgaggtgctggacatcagggatatcaacgaacaacgcaaaccactgaccgattcgcaacgcgtgaagttcacgaaggaaattaaggggcttaagatcgaaattacccactgtggtacgatgcgacgaaagtaccgcgtctgcaacgtgacgcgaagacccgcacaaatgcaatccttcccgttgcagctggaaaacggccagacggtcgaatgtacggtggccaaatacttcctggacaagtataagatgaagctacgctatccgcatctgccgtgtcttcaggtgggtcaggagcataaacacacgtacctcccgctagaggtatgcaacattgttgccggtcagcggtgcatcaagaagctgacagatatgcagacgtctaccatgattaaggcgacggctcgatcagctccagatcgggagcgagaaattaacaatctagtgcgacgggctgatttcaacaacgacgcgtatgtgcaggaattcggtttgaccatttccaacaacatgatggaagttcgaggtcgggtccttccgccacctaagctccagtatggaggccgcgtttccagcatgagtggacaattactctccggtccacagaataaggtgagcttagcattaccaaaccaaggggtttgggatatgcgaggcaaacaatttttcactggcgtcgagattcgcgtgtgggctattgcctgctttgcgccccagcgcacggtacgggaggatgcattgcggaacttcacccagcagctgcagaagatatccaacgacgctggcatgccgatcattggacagccttgcttctgcaaatacgctaccgggccggatcaagtggaaccgatgttcagatatctgaagagcaccttcagccacttgcagctcgtcgttgtggtcctgcccggcaaaacacccgtttacgccgaagtgaagcgcgttggcgatacagtgctgggaatggctacacaatgcgtgcaagcaaagaacgtgaacaaaacttccccacagacgctgtccaatctctgcttgaagatcaacgtgaagctgggtggaattaactcgatcctggtgccatcgatcagaccaaaggtattcgacgagcccgtcattttcctcggtgcagacgtgacacatcctccggctggcgataacaagaaaccctcgatagctgccgtcgttgggtcgatggatgcgcatccgtcgcggtacgcggcaacggtgcgcgtgcaacagcaccgacaggaaataattcaggagctgagcagcatggtgcgtgagctgctgatcatgttctacaaatcgaccggtggattcaaaccgcaccgcatcatactgtaccgtgatggcgtttcggagggtcaattcccgcatgtgctgcagcacgagctgacggcgatccgtgaagcgtgcataaagcttgaggcggactacaagcccggcataacattcatcgtggtgcagaagcgccatcacacgaggctgttctgtgcggacaagaaggaacagagcggcaagtcgggcaacattccagccggtacgaccgtggacgtaggcattacgcatccgaccgagttcgacttttatctctgcagtcaccagggtattcagggcacgagtcgtccgtcacattatcacgttctctgggatgacaatcactttgaatcggacgagctgcagtgcctcacgtaccagctgtgccacacgtacgtccggtgtactcgatccgtttccattccagctcctgcctactacgcacatttggtcgcatttagggcgaggtatcacttagtggagaaggagcacgattccggcgaaggatctcatcagagtggctgttccgaggatagaacgccgggtgcgatggctcgtgccattaccgtacacgccgataccaaaaaggttatgtacttcgcctaa

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