LOCUS       XM_053033111            7766 bp    mRNA    linear   INV 23-FEB-2023
DEFINITION  PREDICTED: Anopheles moucheti protein argonaute-2 (LOC128297468),
            transcript variant X1, mRNA.
ACCESSION   XM_053033111
VERSION     XM_053033111.1
DBLINK      BioProject: PRJNA918695
KEYWORDS    RefSeq.
SOURCE      Anopheles moucheti
  ORGANISM  Anopheles moucheti
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Nematocera;
            Culicoidea; Culicidae; Anophelinae; Anopheles.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_069140) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_943734755.1-RS_2023_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/23/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7766
                     /organism="Anopheles moucheti"
                     /mol_type="mRNA"
                     /db_xref="taxon:186751"
                     /chromosome="2"
     gene            1..7766
                     /gene="LOC128297468"
                     /note="protein argonaute-2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 114
                     Proteins"
                     /db_xref="GeneID:128297468"
     CDS             494..3361
                     /gene="LOC128297468"
                     /codon_start=1
                     /product="protein argonaute-2 isoform X1"
                     /protein_id="XP_052889071.1"
                     /db_xref="GeneID:128297468"
                     /translation="

MSTERELTPGSTQQLHPLSYSDMATHIQLNGVIMGKSFNESPWTSSPPRPPSPSQSQTSFDTLSPPPAGATVNPTTVATTTGTQGAQALGVVPATPPAPPDLPVFTCPRRPNLGREGRPIVLRANHFQITMPRGYVHHYDINIQPDKCPRKVNREIIETMVHAYSKMFGALKPVFDGRNNLYTRDLLPIGNDRVELEVTLPGEGKDRVFRVTIKWVAQVSLFNLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPDGYYHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGTMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYKMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVRRADFNNDAYVQEFGLTISNNMMEVRGRVLPPPKLQYGGRVSSMSGQLLSGPQNKVSLALPNQGVWDMRGKQFFTGVEIRVWAIACFAPQRTVREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKSTFSHLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILVPSIRPKVFDEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIIQELSSMVRELLIMFYKSTGGFKPHRIILYRDGVSEGQFPHVLQHELTAIREACIKLEADYKPGITFIVVQKRHHTRLFCADKKEQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFESDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGCSEDRTPGAMARAITVHADTKKVMYFA"

     misc_feature    845..1234
                     /gene="LOC128297468"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    1262..1414
                     /gene="LOC128297468"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    1415..1777
                     /gene="LOC128297468"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1571..1573,1616..1618,1658..1660,1670..1672,
                     1724..1726,1745..1747,1751..1753)
                     /gene="LOC128297468"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1913..3232
                     /gene="LOC128297468"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2363..2365,2375..2377,2411..2422,2429..2431,
                     2453..2455,2462..2464,2474..2476,2486..2488)
                     /gene="LOC128297468"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2567..2569,2573..2575,2786..2788,3200..3202)
                     /gene="LOC128297468"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

ttcatgtgagaattgtttttcttccccaagtgagatctttttccgtagtgctgtgaaagatccacgggagggaacaaattcggatgcggagttagcgaaaagggtgccattgcatatttcactcggtgtgaaaagttgcacagtgtcacgcagtttacacctgtgaagtgaaaaattgccccccatacacatatacacacctgcgtacacttgtgaacggagaacggtgaaaaatccattcacagtcgagtagcctacgattagaaccatttactgcaaagtgatatcgaagaggaaatccattcgttaagggtccgaaactcttttagaagcccttacggatgtgctgtttggaacatttgtattgaaaagtgtgtaacatttgttgttgaaatggaaagtttgacgtacaatcttcaatcgatatcacccactcggcaagatgggagtgttgcaccgtttgttgcagacggcgcacgattgaagtgaagcaatgtccacggaaagggaactaactcccggatcaacgcagcaattgcacccgctgtcctactcggatatggccacacacattcaactgaacggagtaataatgggcaaatcgtttaatgaatcaccatggacttcttcgccgccaaggcctccaagtccgtctcagtcgcagaccagcttcgatacactctcaccaccaccagcaggtgcgacggtcaacccgacaacggtggcgacgacgaccggaacgcaaggtgctcaggcactcggtgtcgtaccggccacaccaccggccccaccagacctaccggtgttcacatgtccgcgccggccaaatttgggccgcgaaggccggccgattgtgctgcgggcgaaccacttccagatcacgatgccccggggctatgtgcatcactacgacattaacatccaacccgacaagtgtccccggaaggtgaaccgcgaaatcatcgaaacgatggtgcacgcgtacagcaaaatgttcggcgccctcaagccggtgttcgacgggcgtaacaatttgtacacgcgcgatctgctaccgatcggtaacgatcgcgtcgagctggaggtgacgttgcccggcgagggcaaggatcgtgtgttccgcgtcacaatcaagtgggtggcccaggtgtccttgttcaatctggaggaagcgctcgagggtcgcacccggcagataccgtacgacgctatactggcgctggatgtggtgatgcgccatctgccgagcatgacgtacacaccggtcggaagaagtttcttcagttccccggatggttactatcaccctctgggtggaggccgtgaggtgtggtttggtttccaccagagcgtcagaccatcgcagtggaagatgatgctaaacattgacgtgtcggctaccgccttctacaaagcacaaccggtgatcgagttcatgtgcgaagtgttggacatcagagacatcaacgagcagcgcaaaccgttgaccgattcgcagcgcgtcaagtttacgaaggaaatcaaggggcttaagatcgaaattacccactgtggtacgatgcgacgaaagtatcgcgtctgcaatgtgactcgacgacccgcacaaatgcaatcgttcccgttgcagctagagaacggccaaacggtagagtgtacggtggcgaaatacttccttgacaagtataagatgaagctgcgctatccgcatctgccctgtctgcaggtgggccaggagcacaaacacacttacctcccgctggaggtatgcaacattgtggccggtcagcgttgcatcaagaagctgacggatatgcaaacgtctaccatgatcaaggcgactgcccgttcggctccggatcgagagcgagaaatcaacaatctggtgcgtcgggctgatttcaacaacgacgcgtatgtgcaggagtttggtttgaccatctcgaacaacatgatggaggtgcgaggacgtgtgcttccgccaccgaagctacagtacggaggtcgcgtttccagcatgagcggacaattactctccggtccacagaataaggtgagcttagcattaccaaaccaaggggtttgggatatgcgaggcaaacaatttttcactggcgtcgagattcgcgtatgggctatcgcctgtttcgcaccgcagcgcaccgtacgggaggatgcactacggaactttacccagcaattgcagaagatttccaacgatgctggtatgccgatcattggtcagccatgcttctgcaagtacgccaccggcccggatcaggtggagccgatgttcagatatctgaagagcaccttcagtcacctgcagctcgtcgtcgtggtgctgcccggcaaaacacccgtttatgcggaagtgaagcgagttggtgacacggttctcggtatggcgacacaatgtgttcaggctaaaaatgtcaacaagacgtcaccacagacactgtccaatctctgcttgaagatcaacgtgaagctgggcggtatcaactcgattctggtgccatcgatcagaccaaaggtgttcgacgagccagtcattttccttggcgccgatgtaacacatccaccggccggtgataacaagaaaccctcaatagcagcagtggtcggttcgatggatgcgcatccatcgcggtacgcggccaccgtccgtgtacagcagcaccgtcaggaaattattcaggagttgagtagtatggtgcgggagctgctaattatgttctacaaatcgaccggtggtttcaagccgcaccgcatcatactgtaccgagacggtgtatcggaaggtcagttcccgcatgtgcttcagcacgagttgacagcgattcgtgaggcgtgcataaagctggaggcagactacaaaccaggcatcacgttcatcgtggttcagaagcggcaccacacgaggctattctgtgcggacaagaaagagcaaagtggcaaatcgggcaacattccagccggtacgaccgtcgatgtgggcattacccatccgaccgagttcgacttttacctgtgcagtcaccagggcattcagggcacgagtcgtccatcccattaccacgtgctctgggatgacaatcacttcgagtcggacgagctgcagtgcctaacgtatcaactgtgtcacacgtacgtgcggtgtactcgatccgtgtccattccagctcctgcctactacgcacatctggtggcatttagggcgaggtaccacttggttgagaaggagcacgattctggcgaaggatcccatcagagcggttgctccgaggacagaacgcctggtgcgatggcacgtgccattaccgtacacgccgataccaaaaaggttatgtactttgcttaaattgccgcaacagctcacaagacgaccagaccgtgtctgagaaggcgtgaaagagtggaaaaacaaatcaaaacacaaatcgaacaacattctagcttccccccaattgtgtgcacccttgcaaccccgttcctgctgcggtgaaagcaggtgctggcgaaagaatagcatcagcagtagcaataacaatgtgcagcaggagcagcaccaggatgtgcagatcgtcaatccaattcaagtactatttttatatccagatctcgccgattgataggagttgtaatgccgccaactgatgctttaatttttggaccataattcttaagcgtgagtcgcgctttacccaacgccacccaacagtgaaatatgtgtgtagcgatcacgcacacaaacagaatcaagcaaatgagtaaggagacactatatgctaagtacaatagcgttttatcattgcatcacttctcaaagaaaggtgtcatttatgaatggaaaatcagacagatgcatactgaacatttttttaaatgcaacccatggcgatatggcatgtagcagcaacacagtgttttaggttaacatttatttttatatacatctaattattattttacaataggttacgataaaaccttttctattcttccttaattgtgcagtaccagtagcagccagcaggtgatgagaacaaatttgaattcggttcgtgtatagttactttctcttgacctgatattgtataaaaaaaatgcaaaggatttttgtttttgctctgtctttggtaaaccacaaccgctacaaacaatgtttacagtcagtgctgttagtgtatgtaatgtacgtagtctataatagtttagtacaattgaactacaagggatttttatgtcttaacgtatgcgagctatagcgattaccgtgcatctctgcaatcaaatggctaaatgtgtaatgtgttaagcaccttatttcagattatgttacgcattatttgcaatagaataagccagaacaacgattggattatatgattggtttcttttgcagttggcttgagttgaaacggttagatttagcagtgatgaggtcggttgataattggattaagtattgcggagcatgcttcgctaatgtgtcctccattgcatacgataggttctgctgtacactgctcaaaagtgcaacattagccacgcgtttgcgttgggcgttggtctacttctcaggctgggtcatagtgtttatttgtcctcttcgcgatctccgtcactcagtttcaacacagtttatatcgctcgccctaccgaaacattgcttacaccgctcaacaaagtgaataatgtttgcatacgcataagttaatctgcttttaatactagcacaagctctcactacttacaagtaagccccttttctcacaatccccacatcagcattactgttgtaaatagtttccaactgttcacgtttgagttaggcgcttttttcttgtaataaatgcggtcgtttgattggattgaaatatttatggtttgccctatatctctgagacacgtttctaaacacacagtctgtcagtgagggcggtgcgcggttgtttgctcaaacaacagcacacagtttaatcgtgccgggaattcttaagaagatttaacacaatcaaaccaaactgttcaacacattttacatttaaggattgtcgcatcaagaagacatgtttgtgccgggataaaatcgaataagcaacctatttacgccaacgaaattcatcaaaaaacattaaacaaatctagaattagcggaactctaagaaatgaatgtgaacatagattcttaacaaaacaaaaaaaaaaaaccaaccgaaaatcacaatacgttgtcagctgctatgtaccattaggtggaatatttaaaacatgtaaaaattttacaggaacatggtatggttgtcgtaaaacagaacaacccctctcgaatggaaggaggcaattttatcaatgcaaaatgtgtcaaaagtacgatgccacgatgcgatagcgagggtagggaggtagggttgaggatatgtagcaatgtcctgtatgcatctacaggaacgcaggttcagctctaaagcgtgcgatgtagacagatatataggggtctgtgcggatgtgtgcaggtgctgctgcagtagaaatcgggctgctacacttaatcgtatgatacttatagtaggaaggaacaatttgttttgtttatttgtttgtttgcgatcgaattctatcatgagcgaattaacccacccagagaacccaataacaatacacaataaccgactgaccctccccccccccccccccccatttcaaggcatgtcgtaagaaaaagagaatcaaaaacaaagtttcctttacagcaaagtgtgttagcatatattgttgtagtcgatcgcatgaaggtttcagtaaatgttccggtacgggaagctaaatcaaatagcgcgaaccaaattgaaccgtagcaacatggccacatctgccagagttgttggtgtaagggcacgtgtgtgagtgtgtttcaacggaaggtgaatcaagatacattcgtttgaaccaacaccaccaccctgtgaaatagatttagagcaatgtgcaaagaaaaaaaaaacaaaacaaactcaaatcaagtctcttagcattatcagcatccactttcgccggatcggttaatttagtgtttacccttgccccgaaccattttgctttctcattgaaattcgtgtttcaagctgttgtaggattaatatgttggcaaaacgagcaacacaaaaaggaagtaaataacaaatcacatgtagacaaactatttatcacaaagacaacaccgtgtaatgtgtgtgagggcagcgcagtgaaggattttaataatggcaacatttttgtggtgtgacacggtgcaagatgttagtcaagatttgctcgtcgcgataggattgcgtggcttccttatttaactttattcaagccaagagagagaggagaacgcgaacgggaatataatgattcttatatgaagcggatggttagggttttgtttcccgatagtggaaatagaatatcagatcaggtggcgcgcggatgtacgatgatggatggtatcgatgtgtatggtgtgtcagtcacaggccactatcatcagtaccgcatccatgaaacaaaccagacatattagtaaggcggtcaaagtgccaccaataagatgaaacttgagtccgggaattagattgtaaggtttaataaaacaaaaggaagtactttattacaaaacaaaatacccattaatggcgaccaccaaattgcgacgttcttctgcaaaacggggacgagcgctcgatgagatcaacagaagaaagctacacaggaacacaaacactaacactttacgaacgatttatacaagctgacgcgcatcttcgataggtagcggtgtgtaaacaacaaaggaacgccaacaaaattaggatgtatgtgctctttttttctccttaatttattaagcaacacacaaccaccacaacacaagcgcaactgagaaaggtttctccaaaaatacacaaaaaatctaaaaaactcacctacgtataggttatatactgatgttgttttaaaatccatgggcggctggtttccttttgtggaaaggcgtgtaagaaatgctagtaaggaacggttgcttgaatgttttagcttgtaattacaacggagcacaagtcggtcggtcggttttcgcgtatcgtagcgtcacagtatacagttcacactccccacatggaaggtcctggtgaacttttactacgccaagtgcttttggtgcagcagcagaagggccgaagacccattctttatctcttgtttgctgaacaaaaaaacacacaaaatggaaaacgagtgagaatgaccaaacataaatagtgggaaagaatgttgtaccgaacgtaaactggagaagcacatcggatgcataacgtgacaaatgaaaccaacacacaacacagtgaccaaacacacaaaaaaacgcagacgctgaatgtacggggggccgtaaagaatggtaacaaataactatattcaacttatacaagggatttataacatattaaggtagtcaaaaggaggagggaagtaaaaagggaagaaaaagccagaaatccaattaatggtaaagcagcggagcgtaacgagcggcagcgaaacaacattaaaaagcaaaattgtattttagataaaaaagcaacctaaaatcatgaaaaaagagaaatctttctaaaactccccgcccccccacgggagggtggtttaaggcaaattagcaagtaagaagcaaccacaacaacaacaacaaagcataaactttattgatgaatgga

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