LOCUS       XM_052992416            2579 bp    mRNA    linear   INV 14-JAN-2023
DEFINITION  PREDICTED: Drosophila gunungcola protein argonaute-2-like
            (LOC128259818), transcript variant X2, mRNA.
ACCESSION   XM_052992416
VERSION     XM_052992416.1
DBLINK      BioProject: PRJNA922093
KEYWORDS    RefSeq.
SOURCE      Drosophila gunungcola (fruit fly)
  ORGANISM  Drosophila gunungcola
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_026453181) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_025200985.1-RS_2023_01
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2579
                     /organism="Drosophila gunungcola"
                     /mol_type="mRNA"
                     /strain="Sukarami"
                     /db_xref="taxon:103775"
                     /chromosome="3L"
                     /map="unlocalized"
                     /sex="male"
                     /tissue_type="Thorax"
     gene            1..2579
                     /gene="LOC128259818"
                     /note="protein argonaute-2-like; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 161
                     Proteins"
                     /db_xref="GeneID:128259818"
     CDS             167..2527
                     /gene="LOC128259818"
                     /codon_start=1
                     /product="protein argonaute-2-like isoform X2"
                     /protein_id="XP_052848376.1"
                     /db_xref="GeneID:128259818"
                     /translation="

MTKMPAKAYHYDVKIMPERPKKFYRQAFDQFRTNQLGGAIAAFDGRASCYSVDKLKTNSKDPEVTVIDKQGRTLHYTVEIKETGDLEVDLNSLKSYMTTRIFDKPMRAMQCLEVVMSAPCHQKAVRSGRSFFKTSNPGERKELDGGYEALVGLYQSLVLGDRPFLNVDISHKSFPIAMPVIEYLERFVLKEKINSSKSLEKCGHIAESFLKGLDVIYTPPKAFASASRVYKVNGLSHKPGSSQEFALDGKMTTVAEYFKSRNYRLQFPRLPCLHVGSLTNQIYLPIELCQIEGGQALNRKDDATQVANMIKFAATSTNVRKGKIMHLMKYFEHNNDPSISRFGIKIAADFIMVSTRTLNPPQVEYHGKTFCQARNGSWSMGNMQFLETKPKAHKWAILYFNTGMALYNKVSVFEKLVLAQSESMNIKLEARASIEGYKNKLELDNWFGVLKSKNCDLAFVIFPNAENTYDYIKQRTELHHGLLTQCIKQTTFDQRLTSQTIANILLKVNSKLNGINHKLQDNPLLKSLKNAMYLGADVTHPSPDQREIPSVVGVAASHDPYGASYNMQYRLQRSALEEIKDMESITMEHLRVYRQYRKTYPEHILYYRDGVSDGQFPKIKDEELRGINAACAKLGIKPKICCLIVVKRHHTRFFPSGEPSQYNKFNNVDPGTVVDRTIVHPNEMQFFMVSHQSIQGTAKPTRYNVIENTGHLDIDLLQQLTYNLCHMFPRCNRSVSYPAPAYLAHLVAARGRVYLTGTTRFLDLKREYETRQIVPAFMKTNPMYFV"

     misc_feature    296..514
                     /gene="LOC128259818"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    545..688
                     /gene="LOC128259818"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    695..1039
                     /gene="LOC128259818"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(854..856,899..901,926..928,938..940,989..991,
                     1010..1012,1016..1018)
                     /gene="LOC128259818"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1175..2431
                     /gene="LOC128259818"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1571..1573,1583..1585,1619..1630,1637..1639,
                     1664..1666,1673..1675,1685..1687,1697..1699)
                     /gene="LOC128259818"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1775..1777,1781..1783,1991..1993,2399..2401)
                     /gene="LOC128259818"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

tcagacaacaagaaacttcagtcttgaacatatcttaaaaggtgtggccaatccatcgacgggttccagggcacgaccacctgcacctgcacctgtaggaatcagcaccaagcgaggaaccatcgggagaagcggcacagctgccgtcaattacctgaatgtggacatgaccaaaatgccggcaaaggcctatcactacgatgtcaagattatgcccgagcggcccaagaagttctacaggcaggcattcgaccagttccgcacaaatcaattgggcggtgcgattgccgcctttgatggcagggcttcctgctactcagtggataagctgaaaacaaattccaaggacccggaagtcactgtgatagataagcaagggcgaactttgcactacacggtggaaatcaaggagactggagacttggaagtggatctaaactctctgaagagctatatgacgacgaggatcttcgacaagccgatgcgggcgatgcagtgtctggaggtggtgatgtcggctccttgccaccaaaaggccgttcggtcaggtcgctcctttttcaagacatccaatcctggcgagcgaaaggaattggacggcggatacgaggctctggtcggtctgtatcagtccttggtacttggtgatcgtcccttcctaaatgtcgacatatcgcacaagtcctttccgattgccatgccggtgatcgaatatctggagagatttgtcctgaaggaaaaaatcaacagcagtaaaagtctggagaagtgcggccatatcgctgaatcgttcctcaaaggcctcgatgtgatttacacaccacccaaagcatttgccagcgcttcgcgggtctacaaagtcaatggactgtcgcataagccgggaagcagccaggaattcgcactggatggcaagatgaccaccgtggcggaatattttaagagccgaaactacaggttgcagtttccccggctaccgtgtctgcatgttggatctctgacgaaccaaatatatttaccgatcgaactttgtcaaatcgagggaggtcaagcattgaatcgcaaggatgacgccactcaggtggccaatatgatcaagtttgcggccacttcgacgaacgtgcgaaagggcaagatcatgcacctgatgaagtacttcgagcacaacaatgatccgtccatcagtcggtttggcattaagatcgccgccgattttataatggtgagcacccgcaccctgaacccaccgcaagtggagtatcacggcaagacgttttgccaggcgaggaacggatcgtggagcatgggcaatatgcagtttctggagaccaagccgaaggcccacaagtgggcgattttgtactttaatacaggcatggcactttacaacaaggtcagcgtattcgagaaattggtgcttgcacaaagcgagtcgatgaacatcaagttggaggccagggcttcaatagaggggtacaagaacaaactcgaactggacaattggttcggggtactgaagagcaagaattgcgatctggcgtttgtgatctttccgaatgctgagaacacctacgactacatcaagcagaggaccgagctgcatcatggcctcctgacgcagtgcatcaagcagaccaccttcgatcaaagactgacctcacagaccattgcaaacatactacttaaggtaaactccaagctgaatggcatcaaccacaagctccaggataatcccctgttgaaatcgctcaagaacgccatgtacttgggtgccgatgtgacccatccgtcgcccgatcagcgcgagattcccagtgtggtgggcgtggcagcctcccacgatccctacggagcctcctacaacatgcagtatcgcctgcagcggtcggctctggaggagatcaaggacatggagtcgataacgatggagcatctgcgtgtgtatcgccagtacagaaagacctatccggagcacatcctctactaccgcgacggggtgagcgacggacagttcccaaagatcaaggacgaggagctgaggggcattaatgcagcctgtgctaagttgggcatcaagcccaagatttgctgcctgattgtggtgaagcgtcaccacactcgcttcttcccgagcggcgagccatcgcagtacaacaagttcaacaacgtggatcccggaaccgtggtcgatcgcaccatcgtgcatcccaacgagatgcagttcttcatggtcagccaccagtccatccagggcacggccaagccgacgcgctacaatgtgattgagaacactggccacctggacatcgacttgctgcaacagttgacctacaacctgtgccacatgttcccccgttgcaatcgctcggtttcatatccggctccggcctacttggcccacttggtggcagcgcgcggacgtgtttacctcactggcaccactaggttcctggacttgaagagggaatacgaaacgcgccagattgtgcccgcattcatgaagacaaaccccatgtactttgtataagcattaattaaggatcacaaatcggaaatagaaatttctccaaaaaaatata

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