LOCUS       XM_049596220            3008 bp    mRNA    linear   VRT 23-JUL-2022
DEFINITION  PREDICTED: Epinephelus fuscoguttatus dicer 1, ribonuclease type III
            (dicer1), transcript variant X3, mRNA.
ACCESSION   XM_049596220
VERSION     XM_049596220.1
DBLINK      BioProject: PRJNA859906
KEYWORDS    RefSeq.
SOURCE      Epinephelus fuscoguttatus (brown-marbled grouper)
  ORGANISM  Epinephelus fuscoguttatus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Eupercaria; Perciformes; Serranoidei; Serranidae;
            Epinephelinae; Epinephelini; Epinephelus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_064765) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: Epinephelus fuscoguttatus Annotation
                                           Release 100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3008
                     /organism="Epinephelus fuscoguttatus"
                     /mol_type="mRNA"
                     /db_xref="taxon:293821"
                     /geo_loc_name="China"
                     /collection_date="2018-12"
                     /linkage_group="LG14"
                     /note="scaffold1"
     gene            1..3008
                     /gene="dicer1"
                     /note="dicer 1, ribonuclease type III; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 Proteins"
                     /db_xref="GeneID:125900927"
     CDS             381..3008
                     /gene="dicer1"
                     /codon_start=1
                     /product="endoribonuclease Dicer isoform X2"
                     /protein_id="XP_049452177.1"
                     /db_xref="GeneID:125900927"
                     /translation="

MAGLQLVTPATSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALEHNTIVCLNTGSGKTFIAVLLTKELSHQIRGHYQENAKRTVFLVNTALSVVQQAAAVRTHSDLQVGEYTDLEETSAWTDQRWSQEIIENQVLVMTCHIFLHVLRNKILPLSKINLVVFDDCHLAITDHPYCEIMKLFEGCSCSPRILGLTASILNGKCDPSELELKIQNLERILKSNAETATDLVVLDRYASQPREVVLDCGPYVDKSGLSSCLQAELDEALHFLNDCNISVAREDRDPTFISKQVLSDCLAVLQVLGPWCADKAAGIMVRELQKYIKHEQEELNRKFLLFTDTILRKVHALCEEHFSPASLDLKFVTPKVLRLLEILHEYKPFERQQFESVEWYNNRNQDNYVSWSDSEDEDEDEEVEAKERPEANFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHSIGKNQPRNKQMEVEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPVSNYIMLADSERTKAFEEDLTTYKAIEKILRNKCSKSVEVSEFEVEQVMDDDNILPPYVLRSEDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCKTTEKLDERFQSTLYLPINSPLRVPVKGPTMNCARLAEKAVALVCCEKLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYAVPEQTYYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPRIPHFPVYTRSGEVTISIELQKSGFTLTTAQLDLITRLHQYIFSHILRLEKPALEFKPTLADSAYCVLPLNVGE"

     misc_feature    474..1067
                     /gene="dicer1"
                     /note="DEXH-box helicase domain of endoribonuclease Dicer;
                     Region: DEXHc_dicer; cd18034"
                     /db_xref="CDD:350792"
     misc_feature    order(474..485,492..494,543..566,687..689,876..878,
                     969..971)
                     /gene="dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350792"
     misc_feature    order(651..656,723..728,801..803,807..812,819..821,
                     894..902)
                     /gene="dicer1"
                     /note="nucleic acid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:350792"
     misc_feature    1161..1445
                     /gene="dicer1"
                     /note="Partner-binding domain of the endoribonuclease
                     Dicer; Region: Dicer_PBD; cd15903"
                     /db_xref="CDD:277191"
     misc_feature    order(1176..1181,1188..1190,1194..1199,1374..1379,
                     1386..1391,1398..1400,1407..1412,1419..1421)
                     /gene="dicer1"
                     /note="Trbp binding interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:277191"
     misc_feature    1659..2042
                     /gene="dicer1"
                     /note="C-terminal helicase domain of the endoribonuclease
                     Dicer; Region: SF2_C_dicer; cd18802"
                     /db_xref="CDD:350189"
     misc_feature    order(1695..1703,1911..1913,1968..1970,1974..1976)
                     /gene="dicer1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:350189"
     misc_feature    order(1923..1925,1929..1931,2004..2006,2010..2012)
                     /gene="dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350189"
     misc_feature    2238..2504
                     /gene="dicer1"
                     /note="Dicer dimerization domain; Region: Dicer_dimer;
                     pfam03368"
                     /db_xref="CDD:460900"
ORIGIN      

gaaaggaagtggtcccaccgtgaacaagtagctaccaaatcggggcagcaagactgaatggcagtgaggatatccaacgaatgatttgaagcattttttgccaagactatcaattgaaacacataccccagagctggaggacccagtcacaatccctgccactttccatctgtgtaaaggtctgtttccaactaaatgtggggaagcatcaggagcatcagattaagagatattttatcatgaagcccagattaagtgttgtctgcttatccagaaagtctcagttattaccttgaacttgtgaaaagaagaggatgatgatatgagataaagtggacaaccggaggagcccagccccctcacctccacctctttgaagcatggcaggcctacagcttgtcacccctgccacttcacccatggggcctttctttggcctgccatggcagcaggaggctatccacgataacatctatacacctaggaaatatcaggtagaacttcttgaagcagctcttgaacataatactattgtctgcttgaatactggctcagggaagacctttattgcagtacttctaacaaaagagctctcccaccaaatccgtggacattaccaagaaaatgcgaagaggactgtttttctggtgaacacagctttgtctgtagttcagcaagcagctgcagtcaggactcactctgacctccaagtgggagagtacacagatctggaggagacctcagcatggactgaccaacggtggagtcaagagataatcgagaatcaggtgctggtcatgacttgccacatattcctgcacgttctgagaaataaaatcttaccgttgtctaaaatcaacttggtggtttttgatgattgtcacctggccatcacagaccacccttactgtgagataatgaagctgtttgagggctgctcctgcagtcctcgtatcctgggtctcacagcctccattctgaatgggaagtgtgatccgtcagaactggagctgaagatccagaatctggagagaatcctgaagagcaacgctgaaactgccactgaccttgtggtcctggacagatatgcctcccagcccagagaagtggtgctggactgtggtccctatgttgataagagtggcctctcttcctgccttcaggcagagctggatgaagctctccacttcctgaatgactgcaacatatctgttgccagagaggaccgggaccccacgttcatctccaaacaggtcctcagtgactgcctggctgtgctgcaggtgctgggaccctggtgtgcagataaggcagcaggcatcatggtgcgggagctccagaagtacatcaaacatgagcaggaggagctcaaccgcaagtttttactcttcactgacaccatcctgcgcaaagtgcatgcactctgtgaggagcacttctctcctgcctcgctggatctcaagtttgtcacccccaaggtcctccggctgctcgagatcctgcatgaatacaagccctttgagcggcagcagtttgaaagcgtggagtggtacaacaaccgcaaccaggacaactatgtgtcctggagcgactccgaggacgaagatgaggatgaggaggtggaggccaaagagaggcccgaagccaactttccctcaccgttcaccaacatcctctgtgggatcatctttgtggagaggaggtacacagctgtcgtcctcaatcgtctgatcaaagaggcggggaagcaggacccagagctggcttacatcagcagcaactttatcacgggtcacagcatcggcaagaaccagccacggaacaagcagatggaggtggagttcaggaaacaagaggaggttcttcgcaaattccgggctcatgaaaccaacctgctaattgccaccagcatcgtggaagaaggtgtggatatcccaaagtgtaatttggtggtgcggtttgacttgcccacagagtacaggtcctacgtccagtccaaaggcagagctcgagcacctgtctccaactacatcatgctagctgacagtgagagaaccaaagcctttgaagaagatctcactacctataaggccatagaaaagatcttaaggaacaagtgctccaagtcagtggaggtgagtgagtttgaagtggagcaggtgatggacgatgacaacatcctcccaccctacgtgcttcgatctgaggatggaggtccccgggtcaccattaatacagccattgggcacatcaacaggtactgtgctcggcttcccagtgacccattcacccacttagcacccaagtgtaaaactactgagaagctggatgaacgcttccagtccacactctacttacccatcaactcccctctgcgagttcctgttaagggtcctacaatgaattgtgccagactggcagagaaagcagttgcactagtatgttgtgagaaactccacaaaataggtgagctggacgatcacttgatgccggtgggaaaggagacagtgaagtatgaagaggagctagaccttcacgatgaggaagagaccagcgtaccaggccggcctggctctaccaagaggaggcagtgctaccctaaagccataccagagtgtctgcgggacagttatgctgtacccgagcagacttactacctatatgtgattgggatggtcctcaccacccctctccctgatgagctcaacttccgcagaaggaagctctacccaccggaggacaccacaaggtgcttcggcatcctgactgccaaacctatacctcgaattccccatttcccagtgtacacccgctcgggtgaggtgaccatctccatcgagctgcagaagtctggtttcacgctcaccaccgcccagctcgacctcatcacccgcctgcaccagtacatcttctcccacatcctccgcctggagaaacctgcactggagttcaagcccacgctggctgactcggcttattgcgttctacctctgaatgttggtgagtag

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