LOCUS       XM_049476318            3172 bp    mRNA    linear   VRT 21-JUL-2022
DEFINITION  PREDICTED: Astyanax mexicanus argonaute RISC catalytic component 3b
            (ago3b), transcript variant X3, mRNA.
ACCESSION   XM_049476318
VERSION     XM_049476318.1
DBLINK      BioProject: PRJNA853366
KEYWORDS    RefSeq.
SOURCE      Astyanax mexicanus (Mexican tetra)
  ORGANISM  Astyanax mexicanus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Characiformes; Characoidei; Acestrorhamphidae; Acestrorhamphinae;
            Astyanax.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_064410) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: Astyanax mexicanus Annotation
                                           Release 103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3172
                     /organism="Astyanax mexicanus"
                     /mol_type="mRNA"
                     /isolate="ESR-SI-001"
                     /db_xref="taxon:7994"
                     /chromosome="3"
                     /sex="female"
                     /tissue_type="muscle"
                     /dev_stage="adult"
     gene            1..3172
                     /gene="ago3b"
                     /note="argonaute RISC catalytic component 3b; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 Proteins"
                     /db_xref="GeneID:103034630"
     CDS             674..3172
                     /gene="ago3b"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X3"
                     /protein_id="XP_049332275.1"
                     /db_xref="GeneID:103034630"
                     /translation="

MEIGTTGAVGAAPLLSVPRRPGYGTMGKPIKLLANCFQVDIPKMDVYLYEVDIKPERCPRRVNREVVDSMVQHFKVTIFGDRKPVYDGKRSLYTAHPLPVATGGVDLDVTLPGEGGKDRPFKVSIKFVSLVSWHMLHEVLTGRTMPEPIDLDKPISTNPVHAVDVVLRHLPSMRYTPVGRSFFSSPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQQVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYEADPFVQEFQFRVRDEMAEVTGRVLPAPMLQYGGRVSSEHFLNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRYKPTRLIFYRDGVSEGQFRQVLYYELLAIREACISLEREYQPGITYIVVQKRHHTRLFCADRNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDR"

     misc_feature    890..1174
                     /gene="ago3b"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    1202..1354
                     /gene="ago3b"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    1355..1717
                     /gene="ago3b"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1511..1513,1556..1558,1598..1600,1610..1612,
                     1664..1666,1685..1687,1691..1693)
                     /gene="ago3b"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1850..3148
                     /gene="ago3b"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2282..2284,2294..2296,2330..2341,2348..2350,
                     2372..2374,2381..2383,2393..2395,2405..2407)
                     /gene="ago3b"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2486..2488,2492..2494,2702..2704,3116..3118)
                     /gene="ago3b"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

ccctccctcagcccggcggtggagagagagatggtgaaccggttacaggagcggagagagtcggagagacgaaccggtgaaccagcgagaaaaacagcccggagctgaacctctgctgcggtgctgagtgttttattatagaaggacgaattttaactggttttagactgtaataaactgtggctgagtggaggttggaggttttagtgagttttatcgagtgtcagacagaagctgctgctctggttcgagttgagaagaagggaaaagctgtttctcgctctcgggagtttttacgaggagttggttcggttgtcagctgggagtaattaacgctactgagtcccggtgaacggagggagctactgaaggaggcgaaggacacggcggggaggctgtctttaacctaactaacgataaacaccgagaaccgaatgaagctaaggccgagctgaccctcagggacgggacggtctcatcagccgcagcggagaccggcgaccgcggccggggcgaggaggacagagaggtagccgttagccgagctccagcagctccagcggccccacagcggctccgcggagaccctacagcaccactactaccaccacccgtaagccgggcaccagctctggaaagccggctgactggaatccgggcagagacctcatgaatggaaatcggtactacaggagccgttggggctgcgcccctgttgtctgtgccacgaaggcctggctatggcaccatggggaagcccatcaagttgctggccaactgcttccaggtggacatccccaaaatggatgtctacctgtacgaggtggacatcaagcctgagagatgtccccgccgtgtcaacagggaggtggtggactccatggtgcagcattttaaggtgaccatctttggggacagaaaaccggtctatgatgggaagaggagcctctacacagctcatccgctaccagtggctacaggaggggtggatctcgacgtgaccttgcctggtgagggcggtaaggatcggccctttaaggtcagcatcaagtttgtgtcactggtcagttggcatatgctgcacgaggtgctaacaggacggaccatgcctgagcctatagacctggacaagccaatcagcaccaaccctgtccatgctgtcgatgtggtcctgcgccacctgccatccatgaggtacaccccagtgggacggtccttcttctcctctcctgaaggctatgatcatccactgggtgggggcagggaggtatggtttggattccaccagtcagtgcggccggctatgtggaaaatgatgctgaacatagacgtgtctgctactgccttctacaaagcccagcaggtgatccagttcatgtgtgaggttctcgacatccacaacattgatgagcagccccgtcctcttacagactcccacagagtcaaattcaccaaagaaatcaaaggtctgaaggtggaggtgacccactgcggcaccatgaggaggaagtacagggtgtgtaatgtcactcgccgacctgccagccatcaaacgttccctctgcaactggagaacgggcagactgtggagagaacggtggcacagtacttccgagagaaatacaacctgcagctcaaatatccccatctgccctgtctgcaggtgggccaagagcagaagcacacctatctgcctctggaggtgtgtaatatcgtagccgggcagcgctgcataaagaaactgactgacaaccagacgtccaccatgatcaaagccacagctcgttctgcaccagatagacaagaggaaatcagcagactggtgcgcagcgcgaactacgaggcagacccgttcgtgcaggagttccagttccgtgtgcgggacgagatggccgaggtgacgggccgcgtcctgcccgcccccatgctgcagtacggcggcagggtgagctctgaacactttctgaatcgtacagtggccaccccaagccatggtgtatgggacatgaggggaaagcagttccataccggtgtagaaatcaaaatgtgggccattgcctgctttgccacccaaagacagtgccgagaggagatcctcaagagttttacagaccagctgcgcaagatctctaaagatgcaggcatgcccatccaaggccagccatgcttctgcaagtacgctcagggagcagacagcgtggagcccatgttcagacacttgaagaacacctatgctggcctgcagctcatcatcgtcattctgcctgggaaaacgcctgtctatgcggaggtgaagcgtgttggagacactcttctgggaatggccactcagtgtgtgcaggtgaagaacgtggtgaagacttctccacagactctctccaacctctgcctcaagatcaacgtcaagctagggggcatcaacaacatcctggtcccacatcagcggccatctgtgttccagcagccagttatcttccttggtgctgatgtcactcaccctcctgcaggagatggaaagaagccctcaattgctgcggtggtgggcagtatggatgcccaccctagtcggtactgtgctacagtgcgggtgcagaggcccaggcaggagattatccaggacctggcctccatggttcgagagctgctcatccagttctacaaatccactcgatataaacccacccggctcatcttctacagggacggcgtgtccgagggacagttccgacaggtgctgtactacgagctgctggccattcgtgaggcctgtatcagcctggagagagagtaccagcctggcatcacgtatatcgttgtccagaagcgccaccacacacgccttttctgtgcggaccgcaatgagagggttggacggagtggtaacattcctgctggtaccacagtggacacggatatcacccatccatacgagtttgacttttacctttgcagtcatgctggaatacagggcacaagccgtccttcacactaccacgtgctgtgggatgacaactgcttcacagctgacgagtttcagctgctaacctaccagctgtgccacacgtatgtgcgctgcacccgctccgtgtccatcccggcaccagcctactacgcccacctggttgccttccgagcccgctaccacctggtggacaaagagcacgacaggtga

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