LOCUS       XM_049467560            2613 bp    mRNA    linear   VRT 21-JUL-2022
DEFINITION  PREDICTED: Astyanax mexicanus argonaute RISC component 1 (ago1),
            transcript variant X3, mRNA.
ACCESSION   XM_049467560
VERSION     XM_049467560.1
DBLINK      BioProject: PRJNA853366
KEYWORDS    RefSeq.
SOURCE      Astyanax mexicanus (Mexican tetra)
  ORGANISM  Astyanax mexicanus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Characiformes; Characoidei; Acestrorhamphidae; Acestrorhamphinae;
            Astyanax.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_064408) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: Astyanax mexicanus Annotation
                                           Release 103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2613
                     /organism="Astyanax mexicanus"
                     /mol_type="mRNA"
                     /isolate="ESR-SI-001"
                     /db_xref="taxon:7994"
                     /chromosome="1"
                     /sex="female"
                     /tissue_type="muscle"
                     /dev_stage="adult"
     gene            1..2613
                     /gene="ago1"
                     /note="argonaute RISC component 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1 EST,
                     3 Proteins"
                     /db_xref="GeneID:103040377"
     CDS             127..2613
                     /gene="ago1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X3"
                     /protein_id="XP_049323517.1"
                     /db_xref="GeneID:103040377"
                     /translation="

MEPGASGAVPMGPYPPPLQQVFQAPRRPGMGTVGKPIKLLANYFEVEIPKMDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQLFGDRKPVYDGKKNIYTVLALPIGSEKVDFEVTIPGEGKDRIFKVSIRWLAKVSWRLLQETLVSGRLQVPLDSVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKTLTDSQRVRFTKEIKGGSLPGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNANFNLDPYIQEFGIKVRDDMAEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKSERIGKSGNIPAGTTVDTSITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDR"

     misc_feature    229..621
                     /gene="ago1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    649..801
                     /gene="ago1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    802..1179
                     /gene="ago1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(973..975,1018..1020,1060..1062,1072..1074,
                     1126..1128,1147..1149,1153..1155)
                     /gene="ago1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1312..2589
                     /gene="ago1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1723..1725,1735..1737,1771..1782,1789..1791,
                     1813..1815,1822..1824,1834..1836,1846..1848)
                     /gene="ago1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1927..1929,1933..1935,2143..2145,2557..2559)
                     /gene="ago1"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

tttttttagccaggaaagaggcgctttccacggcggggaaagcaggctgtagaggcgagggccggccgtggtggtggtggtggagccccggggcttgcgttgagacggcgcgcctaagtggatgggatggagccgggagcatctggcgctgtgcccatggggccgtacccccctcccctgcagcaggtgttccaggccccccgcaggccgggcatgggcaccgtggggaagcccatcaagctgctggccaactacttcgaggtggagattcccaagatggacgtctatcactacgaggtcgacatcaaacccgacaagtgtccccgacgggtcaacagggaggttgtggagtacatggtgcagcatttcaaacctcagctttttggcgaccggaagccggtttacgacggcaagaagaacatctacacagtcctggctcttcctatagggagtgaaaaggtggactttgaggtgaccatcccgggcgagggtaaggaccgcatctttaaggtgtccatccgctggctggcgaaggtgtcatggcggctgctgcaggagactctggtcagcgggagacttcaggtcccactggactctgttcaggctctggacgtggccatgagacatctggcctccatgaggtacactccagtgggacgatcattcttctccccccctgaggggtattaccatcctctgggaggaggcagggaggtgtggttcggcttccatcagtcagtacgacccgcgatgtggaagatgatgctgaacatagatgtgtcagccacagccttctacaaggcccagcccgtcatcgagttcatgtgcgaggttctggacatccgcaacatcgacgagcagcccaagactttaactgattcccaaagggtccgattcaccaaggagatcaagggtgggtccctacccggactgaaggtggaggtgacgcactgtggtcagatgaagaggaaatacagagtgtgtaacgtcacacgtcgtcctgccagtcaccagacgtttcctctgcagctggagagcggtcagacggtggagtgtaccgtagcgcagtattttaaacagaagtataacctgcagctgaaataccctcacctgccctgcctgcaggtgggccaggagcagaagcacacctacctgcccctggaggtgtgtaatatcgtagctgggcagaggtgcatcaagaagctgacagataatcagacgtccaccatgatcaaagccacggcgcggtcagcaccagacagacaggaggagatcagcaggctgatgaagaacgctaattttaatctggatccatatatacaagagtttgggattaaagtgcgggacgacatggcggaagtgacgggaagagttctcccagcgcccatcctgcagtacggaggcaggaatcgggccatagccacgcccaaccagggtgtctgggacatgagggggaagcagttctacaacgggattgagatcaaagtgtgggccattgcctgcttcgctccacagaaacagtgccgagaggaagttctaaagaactttacagatcagctgcgtaagatctctaaggatgctgggatgcctatccaggggcagccgtgtttctgtaagtacgcacagggagcggacagcgtggagcccatgttcagacacctgaagaacacctactccggcctgcagctcatcatcgtcatcctgcccggaaaaacacccgtatatgcggaggtgaagcgtgttggagacactcttctgggcatggccactcagtgtgttcaggtgaagaacgtggtgaagacgtctccacagacgctctccaacctctgcctcaaaatcaacgtcaaactcggcggcatcaacaacatcctggtaccccatcaacggtctgcagtgtttcagcagccggtgatcttcctcggggccgacgtcactcatccaccagcaggagacgggaagaagccctccattactgcagttgtgggtagtatggatgctcaccccagtcggtactgtgccacggtgcgggtgcagagaccccggcaggagatcatcgaggatctctcctacatggtgcgcgagctcctcatccagttctacaagtccacccgcttcaaacccaccaggatcatcttctacagggacggcgttccagagggccagctgccacagatcctgcactacgagctgctggccatcagagacgcctgcatcaagctggagaaggactaccagcccggcatcacctacatcgtggtgcagaagcgccaccacacccgcctcttctgcgccgacaagtccgagaggattgggaaaagtggcaacattccagccggaaccacagtggataccagcatcacccacccgttcgagtttgatttctacctgtgcagtcatgcaggtattcagggcaccagccgaccttctcattactacgtgctgtgggacgacaatcgcttcaccgccgacgagctgcagatcctcacctaccagctgtgccacacctacgtacgctgcacccgctccgtctccatccccgcccctgcctactacgcccggctagtggccttccgcgcccgctaccacctggtggacaaagagcacgacaggtga

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