LOCUS       XM_035698760            7494 bp    mRNA    linear   MAM 15-JUL-2022
DEFINITION  PREDICTED: Canis lupus dingo argonaute RISC component 1 (AGO1),
            transcript variant X1, mRNA.
ACCESSION   XM_035698760
VERSION     XM_035698760.2
DBLINK      BioProject: PRJNA477859
KEYWORDS    RefSeq.
SOURCE      Canis lupus dingo (dingo)
  ORGANISM  Canis lupus dingo
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
            Canis.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_064257) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jul 15, 2022 this sequence version replaced XM_035698760.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: Canis lupus dingo Annotation Release
                                           102
            Annotation Version          :: 102
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7494
                     /organism="Canis lupus dingo"
                     /mol_type="mRNA"
                     /isolate="Sandy"
                     /sub_species="dingo"
                     /db_xref="taxon:286419"
                     /chromosome="15"
                     /sex="female"
                     /tissue_type="muscle"
     gene            1..7494
                     /gene="AGO1"
                     /note="argonaute RISC component 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 69
                     long SRA reads, 4 Proteins"
                     /db_xref="GeneID:112642408"
     CDS             213..2795
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X1"
                     /protein_id="XP_035554653.1"
                     /db_xref="GeneID:112642408"
                     /translation="

MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    312..704
                     /gene="AGO1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    732..884
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    885..1247
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1041..1043,1086..1088,1128..1130,1140..1142,
                     1194..1196,1215..1217,1221..1223)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1380..2666
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1800..1802,1812..1814,1848..1859,1866..1868,
                     1890..1892,1899..1901,1911..1913,1923..1925)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2004..2006,2010..2012,2220..2222,2634..2636)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      7494
                     /gene="AGO1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

gcagctggccgggcgctcgcagggggagctgctgcaggctccgcggcggcggcggcaacggaggctgcgggggcagcggcgcgagcggccgggcttggggggggtgccgagcccggcccggaagcccgagcagccggagtgcggggtccctaggcccctcactctgggctccacagtctccaggccgcctgacctccgcacgggtatatgggatggaagcgggaccctcgggagcagctgcaggcgcctacctgccccccctgcagcaggtgttccaggcacctcgccggcctggcattggcactgtggggaaaccaatcaagctcctggccaattactttgaggtggacatccctaagattgatgtctaccactacgaggtggatatcaagccggataagtgtcctcgcagagtcaaccgggaagtggtggagtacatggtccagcatttcaagcctcagatctttggtgatcgcaagcctgtgtatgatggaaagaagaacatttacactgtcacagccctgcccattggcaatgaacgggttgactttgaggtgacaatccctggggaagggaaggatcgaatcttcaaggtctccatcaaatggctagctattgttagctggcgcatgctgcatgaggcccttgtcagtggccagatccctgttcccttggagtctgtgcaagccctggatgtcgccatgaggcatctggcatccatgaggtacacccccgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctacaaggcgcagccggtgattgagttcatgtgtgaggtgctggacatcagaaacatagatgagcagcctaagcccctcacggactctcagcgtgtgcgtttcaccaaggagatcaaaggcctaaaggtggaagtgacccactgtggacagatgaagaggaaataccgagtgtgtaatgttacccgccgccctgccagccaccagacgtttcccttgcagctggagagtggacagactgtggagtgcacagtggcacagtatttcaagcagaaatacaaccttcagctcaagtatccccacctgccctgcctgcaagttggccaggaacaaaagcatacctacctgcccctagaggtctgtaacattgtggctgggcagcgctgcattaagaagttgaccgacaaccagacttcgaccatgataaaggctacagctaggtcggccccagacagacaggaggagattagccgcctgatgaagaatgccagctacaacctagatccctacatccaggaatttgggatcaaagtgaaggatgacatgacggaggtgacagggcgagtgctgccggcgcccatcttgcagtacggcggccgggtgagcaggaatcgggccattgccacacctaatcaaggtgtctgggacatgcgagggaagcagttctacaatgggattgagatcaaagtctgggccatcgcctgctttgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcagggatgcccatccagggccagccttgcttctgcaaatacgcacagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccagtgtatgctgaagtgaaacgtgttggagatacacttttgggaatggctacacagtgtgtgcaagtgaagaatgtggtcaagacctcgcctcagactctatccaacctctgcctgaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgccgtctttcaacagccagtgatattcctgggagcagatgttacacaccccccagcaggggatgggaaaaaaccttctatcacagcagtggtaggcagtatggatgcccaccccagccgttactgtgctactgtgcgggtgcagcgaccccggcaggagatcattgaagacttatcctacatggtgcgtgagctgctcatccagttctacaagtctacccgcttcaagcctacccgcatcatcttctaccgagatggggttcctgaaggccagctcccccagatcctgcactatgagctgctggccattcgtgatgcctgcatcaaactggaaaaggactaccagcctgggatcacttacattgtagtgcagaaacgccatcatacccgccttttttgtgctgacaagaatgaacgaattgggaagagtggtaacatcccagctgggacaactgtggacaccaacatcacccacccatttgagttcgacttctatctgtgcagccatgcaggcatccagggcaccagccgaccatcacattactatgtcctttgggatgacaaccgtttcacagcggatgagctccagatcttgacgtaccagctgtgccacacttacgtacgatgcacacgctccgtctctatcccagcacctgcctactatgcccgcctggtggctttccgggcacgataccacctagtggacaaggaacatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaagagctgtgccgcccaaatccagaggaagcaaggaggaggagggagggtagggaggagttcagaaggccttgtttccttctacaaagggggcaaaagggtggggaacagggccagtaagccagaccaccagccagaaatctttgatgtccacctcatgacccccacccctccacccatcttgtcacatctggccctgaccccactggaccaagaggggcagcactggtgcccaccatacacacaggtgtctcatgtgactcacagtgctaaagactcatgcctgacagcttgctaaggtcggctctgcagccccgcggacaaaagctggtaggtttgggtttgatactttagatgggagagtgaggggcttgagaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggtctagatttgtttaagaggaaaaacgaaaccagacccagatcaatattttagaatactagatgttttaatgggttgaaaatccagtttgtaggaagatttttaatgctaatgattttggttgctcctcccccagctgacacccctttttcccttattcctttctctctactttgtctaccccaccttacacctcctccctgacagacatccagcccctagtaagacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctactggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctttctttggggggatggggtgggggtgggagaggaggtaggtggggaagaaatacccctaacccaacaagcctctagccagagcgccagctactttgcattcaaaggaattaacttccatattcattgagcttttaaaaagatcacaacctcaagatggttaaagtccattgacatttgcactttcagacatgacaagtctaggagctgctgagatgactggcccttggcctttccacttgacgcctccttttctccctgtcgtcgtcccccccccccccccccccccccagccttcccacctgcctgggtctggagttacttacatcgcatttctcattcttggcttcttttttcccctgatggtcaagtcgattatgtttcaatatttcttaactggggtgtcttataacaaatgatctttaggtctaaaataagaaaaaaaaaaagagcaaaaactaaatgttatttttataccataacttgagtctgttgccaaaatctggaaatccctcccatgcccaataagtttacatcccagaaacattgagccatcagaaggaactatgtacctgacttattctttggcctggctaggtagggagagtggttatctccccaaggtggggctcaggctccacccttcccctgtgcagataatatcgttttcttgctgtaggcgccctcctctgcactgccctgtactcttcctgcaagtgcatcttccctttctctagactgttctctgacactttggctcatcccagattccagtgtgtcctgtggacaggctgggggattttgctgctccctatcgcttctgtttacacaaatgaatttttcccagtttcccactagggcatgtgagtgggtggcatgggcctttgttttgttttgttttgttttgtttttgtctccctggataaagatggggtttggctatcttgcagaactggaaaagtagggggtttctagcttggtgcctgctggccttgaggcaaggccccctctttccttaactgttcatttttttcctatcccactgcttgggatgaggagttgcagcttcagtgtggaagttcctctttgtgaggagcctgggcttgggtttgccccaatctggtgatgaagccatgacactttagacctagctcaggcttggaggccagtctgaatcctggcctgtgtgcttagagctaccatttcccctctccagcagcccttgtacagacccagatttgctatgcaaaacagtctatcccaggttctgttctggttggctactttgttcagcaacttcacaaaacgtagcacaaacattgattatggagaaggcatcaggactgttgagtaactcctcctctacttcttccctactggctacggcatgggatgccccatgggcacagcccagctgaagaacagaatggagggctctgggaggaggcagctcactggagagcctacattccttacacaagtgcctaaagagagtgatgccaacactccatctgccctgtccatcgccttcatatagtgtctacttcgtgttcagtcaccctttggggaggggagctctcttgggacaatgggctctgcatgttctcttctttgggtgcatttaggggctgggatcagggcactgttcctggagggtccagtcattcaccagcatttgcaaatatccatagggagctggtggtaaccacctactctcagcaacaagtttatgttctcctttttctctctttgcctcactctctccatttggattttgagctggggcttaaaaagcattttttagcccttgggcattgcacatgccattcatgaaataaaaaagcaagagaagcagtttgggcaatggcaagaaaatgacttcttgctctgatttctttttttttaatctttgagacttgaaaaatatccttgaccttgaggattattcttgtttgaaagatggtgcatgcagtttgagaagtggtgttagcaacaagctttggatttcttggatttggttaagtggtgcttcttacttgtgctctgagaaagtgttggggggaccccagcctcatcctcttggacaggtctcttgctcccttcattctactctcttgcctctcttttctacttatctctttccctgttgtccttttccttttttcaattcactaagcttgtttgctggcctgcctgcctacgtgatgatgaattctctgcatggctatgataatcccactgttagctagcaaggtcaggcttaatactccttggctgcagaagaccaagaatctgttctccaagcctggtgatgttctctctgggcttgactgccatcgatgttatacaaaggcagatcagcaagcctgcctacctggcatgaaatcaggagggcttctgacaacttccacacctgtccactccttggggttggtttctctcattgctttttctagatctggttccatgtctctactggggcctcccttttctgaggatgtcctagggttgagctacttggtttccggtgttggggggttaggggatggacatgggggaagaagaaagtgatcggaagaaaatgggagagaatttggataaaagatgggaaagagcactgtttattgatcatttttccagtctagtctgacccattgggggttgaggtgctattgctgaaccttgggataagcctggggctattgttgatgggaacttaggtttagaataatgatgaggaaggtacctaaaagcatgaaatctccctaaaaacctcctggttcccacctactagatagccccactaaggcctcctcattggctaagcaacaatgttcttggatgggttttgtttttgtttttgtttctgtttttttggggtccagaattcagtaaatgaggctagcactcaggatgggcagccaaggggacaatttgacttctttgctggcccatggggtatctatctgcaaggctggtggacagtgttttagacctggcatcatgtgtaacaaagaagaatggaagttccttccccttcagggtggaaagtcatctcaaactagccaaaatgcagttttggaaactacattgggggaagttattttttatatttactgggcctcggccaatccaggatggtagctgggatgccttccttttaaagtctgatcatggcagggatatgcagggcactctttcctatttagccttctaagcagattggggagaagggattctctggttttctctttccccccttttattaggacttgccttctccctaggcagggagagaggctaggttggtgctctccccttactctattcctactgacttagaacctctggctgctgtttgggagcctaagaatgggagtggagggaatgggctcaaaataaaacagaataaggtggggaaggcagatttccttctttaaaaaggaaaataggaaaccctccaaggattgtgcaagtaaagacaatgtgtcaaatgcactgagtcccctggtgtagtagcaataaggaaaaatgaaatgactttcctgtgcacacagtccaacccgattggtgtgtgatgttgcacttagcagccatctggtgggcatgtgtgactactctgggtttcactttagtttctaaactttttatccctctcaagtccagcatggatggggaaatgtccctggagccccacagctgtgtacttgtttgcatttgtttccctttgagacttgtgtttgtgtcctgcttcgagctgtaccttgtccagtccattgtaaaattttcccaacagctgtaatgtacagttccttctaaagcaagcaacagcagcacaattctgtgttttataaagacaacagtggcttctatttctaaa

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