LOCUS       XM_030443569            3953 bp    mRNA    linear   VRT 22-JUL-2025
DEFINITION  PREDICTED: Sparus aurata NRDE-2, necessary for RNA interference,
            domain containing (nrde2), mRNA.
ACCESSION   XM_030443569
VERSION     XM_030443569.1
DBLINK      BioProject: PRJNA558036
KEYWORDS    RefSeq.
SOURCE      Sparus aurata (gilthead seabream)
  ORGANISM  Sparus aurata
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Eupercaria; Spariformes; Sparidae; Sparus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_044202.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_900880675.1-RS_2025_07
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 07/21/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3953
                     /organism="Sparus aurata"
                     /mol_type="mRNA"
                     /db_xref="taxon:8175"
                     /chromosome="16"
     gene            1..3953
                     /gene="nrde2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 4 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 21 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:115597547"
     CDS             54..3686
                     /gene="nrde2"
                     /codon_start=1
                     /product="protein NRDE2 homolog"
                     /protein_id="XP_030299429.1"
                     /db_xref="GeneID:115597547"
                     /translation="

MRHTIMALFPAFAEVECDKVDDSTKELDWLNNKSFQTGDALSLHSRYLEKNSERLNKKESSVGREVSSEEEQKEEGSVPSKRKKKKSEKKRKKKKKHKKKSGRYSSSGGSDSETIYPSDLKREEEGDRPQAAPLASRFSWLDDLHSPTEQPFCVDRKADTANWTYKSLYRGDVARYKRKGSSSLGLDPHKQGVSWEESESNKKHKGGDKKKAADRYFSTVSRQLLRSEPPVPTLPTIPDCSDAISPTSFLPLGDNEDNKVGETGDRVQTSSVNPLGVYDSSTALWLQGKGQQAQTEPQKQDTHAEKSAALLAGRTEEFNRRLREQPADTQLWIQFIRYQDELTATVFGMEEEQQGNDLSERSKSSHRAVLEKKLSIAERAVATNPSCVALQLERLRICQELWEPSLLTKEWKKLVFLHPNSAPLWKEYLLFTQSYFSNFTVSKVNSAYGKCLSTLSAVRDGSMVSHPALPGIEEDMLDIFTQQCHFLRQSGHSEKAISLFQAMIDFTFYKPDSVRELSTKQQVEFFEPFWDSGEARVGELGARGWKAWMLQQERGGWLQPSAEEEEDEEEDEEEVKDRSQPRHTIWLDVESSREAAHWLPWRPDKAKGQSEEDCEDPDRQVLFDDIGPSLICLSSPELQLRLLLRFLSFLGLPIDCVLSATPCQPGLLLENLSFLTQGNDLRHPLTSYDLPDLGVNSVGHMTTLQGTRKFAGLGKQGETFVTNVLNMLQPVVPAPHRATLSLSWMQYEKSKVLHCLYGSNKKRLRFQGKRSKRVSKQLLKEPDNRSSLVLWREYAHLEWLLGNLDEARKVFSTATVMGGTKGLKSPSLCELYLLWAQLEVEDGAGVQAGGITAVTVSPAVCVLTRLAEGTSSSSSSSSLSPSPVSILKARKSYEQALTAGLSALDPNLHNPQASRKGKEDLPRLRGLVGCYALFQYLTMGIQAANTIYNQARETMEALYQTLILDKQLNSNEEANLSSTGANQVAAASSHTSRLHVNRLAYECEAVAVQQAALLRYHNSISVFPLATLRQTLTSSLSTWPSSAPLWSIYVQVENRYHSAGRARRFFHSVTRNNSSVVPRLFAIFAEQQRKQLVDAALRSGFHDAALPILPENGLSNRVRGLFERTISTEMCSHCPLLWRMYMHFLLSDGQVDKAKGIFYKALQNIPWAKGLYMDGVQLFPQHLQEFVDLITEKELRLRLPLEELDILLED"

     misc_feature    504..815
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(504..530,537..542,552..557,561..563,567..611,
                     618..626,630..638,672..680,690..695,699..704,711..731,
                     753..764,786..815)
                     /gene="nrde2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1002..1964
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
ORIGIN      

tttattttggtaaaccggccgtcacttgacgtcataatcctgcgactgtttatatgcgacataccatcatggctctgtttccagcttttgcagaagtagagtgtgacaaagttgacgattcgacgaaagaattagactggctgaataataagagttttcagactggagatgccctctctcttcacagtcggtatttggagaagaacagtgagaggctgaacaagaaggaatcaagtgtaggcagagaggtgagctctgaagaggagcagaaggaagagggtagtgtaccatccaagaggaagaaaaaaaagagtgagaagaagaggaaaaaaaagaaaaaacacaaaaagaagagtggaaggtattccagcagcggcgggtctgactctgaaaccatttatcccagtgaccttaaaagggaagaagagggcgacaggccccaggctgctccactagcaagtcgtttctcatggttggatgacctccactcgcccacagagcagccgttctgtgtggaccgtaaagcggacacagctaactggacgtacaagtccttgtacagaggggatgtagccaggtataagaggaaaggcagctcatccttgggtctggaccctcacaagcagggagtcagctgggaggagtcagagtcaaataagaaacacaaaggcggggacaagaagaaggcggcagacagatacttctctacagtcagtcgccagctgttgaggtctgagccccctgttcctacattacctacgattcctgactgcagtgatgccatcagccccacctccttcctcccactgggtgacaatgaggataacaaagtaggagagacgggtgacagagtgcagacatcatcagtaaaccccctgggtgtgtatgactcctctacggctctctggctgcaggggaagggacagcaggcgcagacagagccgcagaagcaggacacacacgcggagaagagtgctgcgctcttggctgggaggactgaagagtttaacaggcggctcagagagcagccggcagacacacagctatggatacaattcatacgataccaggatgagctgactgcaacagtgtttggaatggaggaggagcaacagggcaacgacttgtctgagcgctccaagtcctcccaccgagcagtcctggagaaaaagctgagcattgcagagcgcgctgtggccaccaacccaagctgcgtagctctgcaactggagaggctcaggatctgccaagagctctgggagccctcacttctgactaaagagtggaagaagctggtgttcctccacccaaacagtgcccccttgtggaaagagtatctactgttcacacagagctacttcagcaacttcactgtgtcgaaggtcaactctgcctatgggaagtgtctcagcacgcttagtgctgtgcgggatggcagcatggtctctcatccagccctgccagggattgaagaggatatgttggatatcttcactcaacagtgtcatttcctgcgacagtctggtcactcagaaaaggcaatttccctgtttcaggctatgatcgattttactttctacaaacctgacagtgtacgagaactgtccaccaaacagcaggttgagttctttgagccattttgggacagtggggaggccagggttggagagctgggggccagaggttggaaagcctggatgctccaacaagagcgaggaggttggctacagcccagtgcagaggaagaagaggatgaggaagaggatgaggaggaggttaaggatcggagccagcccagacatacaatctggttggatgtggagtcatctcgggaagcagctcactggctgccttggcggcctgacaaagctaagggccaatcagaagaggactgtgaggacccagacagacaggtgttgtttgatgacatcggtccctccctcatttgcctgtcttcaccagagctccagctccgtcttcttctccgtttcttgtcattccttgggctgcccattgactgcgtgctctctgccaccccctgtcagcctggtctgctgctagagaacctttcttttctcactcagggtaatgaccttcggcatcctctgacctcctatgacctacccgaccttggggtcaactctgtaggtcacatgaccactctccagggaacaaggaagtttgcggggctcgggaagcagggcgagacatttgtcaccaatgtgttaaatatgctccagcctgtagttcctgccccccaccgagccacgctgtcactcagctggatgcagtatgaaaaatccaaggtcttgcactgcctatacggcagcaacaaaaagcgtctccgctttcagggcaagagaagcaagcgggtttcaaagcagctactcaaagaacccgacaaccgctcgtcattggtgctatggcgggagtacgcccacctggagtggttactgggcaacctcgatgaggctcgcaaagtcttctccacggccacagtgatggggggaaccaaagggcttaagagccccagcctctgtgagctgtatctgctgtgggctcagctggaggtggaggacggagcaggtgtgcaagcaggaggaataactgcggtcaccgtgtccccagctgtatgtgtgctaaccaggctagcagaaggaacctcctcatcctcctcgtcatcctccctgtccccatctccggtttccatcctgaaagccaggaagtcatatgagcaagctctgactgcaggcttgtcagccctggacccaaacctccacaaccctcaggccagcagaaaaggtaaagaggacctgcccaggctgaggggcctggtaggctgctacgccttgttccagtacctcacgatgggcatccaagcagctaacaccatctacaaccaggctagagagacgatggaggcgttgtaccaaacactaatacttgataagcagctcaacagtaatgaggaagccaacctttctagcaccggtgctaaccaggttgcagctgcttccagccataccagcaggctccatgttaacaggctagcttatgagtgtgaggcagtagcagtgcagcaggcagcattgctaaggtaccacaatagcatcagtgtgtttccactggcaacgctgagacagacattgacctcttccctctccacctggcccagcagcgcccctctctggagcatatatgtacaggtagagaaccgttaccatagtgctggccgggcacgtcgtttttttcactctgtaaccaggaacaacagcagtgtggtaccacgcctctttgccatttttgctgaacaacaaaggaagcagctggtggatgctgctctgaggtctggtttccatgatgctgcccttcctatcttgcctgaaaatggcctcagcaaccgtgtccgtggactgtttgaaagaaccatatcaacagagatgtgttctcactgtcctttactttggaggatgtacatgcacttcctgttgtctgatgggcaggtggataaagccaaagggatcttctacaaggccttacagaacattccctgggctaagggtttgtacatggacggagtgcagctgttccctcagcatctgcaggagtttgtagatcttataacagagaaggaactccgactcagactgcctttagaggaactggatatactactggaggactgaacactgtatacacgtgtatacacacacctcattcaagaacttcagcccacatagtggcatgtttgatgtcaacaagaagatacagatgcgaaaactctgatgcgtacacacatagccgcagtgttaaacagttaagtttcagtgatgttattaaagatgggcatggagctatccttcggactttatgtatattgttttattttcacagaaaaccaccagctctgtgttttaataccagatacagtcaataaatatgtctctctattc

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