LOCUS       XM_030325234            8612 bp    mRNA    linear   MAM 09-SEP-2020
DEFINITION  PREDICTED: Lynx canadensis argonaute RISC component 1 (AGO1),
            transcript variant X4, mRNA.
ACCESSION   XM_030325234
VERSION     XM_030325234.1
DBLINK      BioProject: PRJNA558991
KEYWORDS    RefSeq.
SOURCE      Lynx canadensis (Canada lynx)
  ORGANISM  Lynx canadensis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
            Felinae; Lynx.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_044310.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Lynx canadensis Annotation Release
                                           102
            Annotation Version          :: 102
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8612
                     /organism="Lynx canadensis"
                     /mol_type="mRNA"
                     /isolate="LIC74"
                     /db_xref="taxon:61383"
                     /chromosome="C1"
                     /sex="male"
                     /tissue_type="muscle, distal limb"
                     /country="USA: Aroostook County, Maine"
                     /lat_lon="42.2466 N 71.6746 W"
                     /collection_date="2017-12-05"
                     /collected_by="Tanya Lama"
     gene            1..8612
                     /gene="AGO1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 long SRA reads, 38 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 14 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:115520655"
     CDS             150..2723
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X4"
                     /protein_id="XP_030181094.1"
                     /db_xref="GeneID:115520655"
                     /translation="

MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    249..641
                     /gene="AGO1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:406799"
     misc_feature    669..821
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:400854"
     misc_feature    822..1184
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(978..980,1023..1025,1065..1067,1077..1079,
                     1131..1133,1152..1154,1158..1160)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1317..2594
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1728..1730,1740..1742,1776..1787,1794..1796,
                     1818..1820,1827..1829,1839..1841,1851..1853)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1932..1934,1938..1940,2148..2150,2562..2564)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gctgcgggggcagcggcgcgagcggccgggcttggggggggtgccgagcccggcccggaagcccgagcagctagagtgctgggtacctaggcccctcactctggactccacagtctctgggccgcctgacctccacacgggtatatgggatggaagcgggaccctcgggagcagctgcaggcgcctacctgccccccctgcagcaggtgttccaggcacctcgccggcctggcattggcactgtggggaaaccaatcaagcttctggccaattactttgaggtggatatccctaagattgacgtctaccactacgaagtggatatcaagccggataagtgtcctcgcagagtcaaccgggaagtggtggaatacatggtccagcatttcaagcctcagatctttggtgatcgcaagcctgtgtatgatgggaagaagaacatttacactgtcacagcactgcccattggcaatgaacgggttgactttgaggtgacaatccctggggaagggaaggatcgaatcttcaaggtctccatcaagtggctagctattgttagctggcgcatgctccatgaggccctggttagtggccagatccctgttcccttggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggtacacccccgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgacgtctcagccactgccttctataaggcgcagccagtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcccaaacccctcacggactctcagcgtgtgcgcttcaccaaggagatcaaaggtctgaaggtggaagtgacccactgtggacagatgaagaggaaataccgtgtgtgtaatgttacccgccgccctgccagccatcagacgtttcccttgcagttggagagtggacagactgtggagtgcacagtggcacagtatttcaagcagaaatataaccttcagctcaagtatccccacctgccctgcctgcaagttggccaggaacaaaagcatacctacctgcccctagaggtctgtaacattgtggctgggcagcgctgcattaagaagttgaccgacaaccagacttcgaccatgataaaggctacagctaggtcggccccagacagacaggaggagattagccgcctgatgaagaatgccagctacaatctagatccctacatccaggaatttgggatcaaagtgaaggatgacatgacggaggtgacagggcgagtgctgccggcgcccatcttgcagtacggcggccggaaccgggccattgccacacctaatcagggtgtctgggacatgcggggaaaacaattctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaagcagtgtcgagaagaggtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcagggatgcccatccagggccagccttgcttctgcaaatatgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccagtgtatgctgaagtgaaacgtgttggagatacactcttgggaatggctacacagtgtgtgcaagtgaagaatgtggtcaagacctcgcctcagaccctgtccaacctctgcctgaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgccgtctttcaacagccagtgatattcctgggagcagatgttacacaccccccagcaggggatgggaaaaaaccttctatcacagcagtggtaggtagtatggacgcccaccccagccgttactgtgctactgtgcgggtgcagcgaccccggcaagagatcattgaagacttatcctacatggtgcgtgagctgctcatccagttctacaagtccacccgtttcaagcctacccgcattatcttctaccgagatggggttcctgaaggccagctcccccagatcctccactatgagctgctggccattcgtgatgcctgcatcaaactggaaaaggactaccagcctgggatcacttatattgtggtgcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggacaactgtggacaccaacatcacccacccatttgagtttgacttctatctttgcagccacgcaggcatccagggtaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcggacgagctccagatcttgacataccagctgtgccacacttatgtacgatgcacacgctccgtctctatcccagcacctgcctactatgcccgactggtggctttccgggcacgataccacctagtggacaaggagcatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaagagctgtgccgcccaaatccagaggaagcaaggaggaggaggagggagggtagggaggagctcagaaggccttgtttccttctttctacgaagggggcgaaagggtgggggacagggccagtaagccagaccaccagccagaaatttctgatgtccacctcatgacccccacccctcacccatcttgtcacatctggccctgaccccactggaccaagaggggcagcactggtgcccgccatacacacaggtgtctcttgtgactcacagtgctaaagactcatgcctgacagcttggtaaggtcggctctgcagccccgcggacaaaagctggtaggtttgggtttgatactttagatgggagagtgaggggcttaaaaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggtctagatttgtttaagaggaaaaacgaaaccagacccagatcaatattttagaatactagatgttttaatgggttgaaaatccagtttgtaggaagatttttaatgctaatggttttggttgctcctcccccagctgccaccccctttccattattcctttctctccactttttctaccccaccttacacctcctccctgacagacatccagcccctagtaagacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctactggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctttctttgggggggatagggtgggggtgggagaggaggtaggtggggaagaaatacccctaacccaacaagcctccaaccagagcgccagctattttgcattcgaaggaattgacttccatattcattaagcttttaaaaagaccacaacctcaagatggttaaaatccattgacatttgcactttcagacatgacaagtcttggagctgctgagatgactggcccctggcctttccatttacacctcctgttcttcctgtccccccggtttccccacctgcctggatctggagttcctttcacagcatttctcactcttggcttcttttttcccctgatggtcaagttgcttatgtttcaatatttcttaactggggtgtcttataacaaatgatctttaggtctaaaataagaaaaaaagagcaaaaactaaatgttatttttataccataacttgagtctattgccaaaatctggaaatccctcccatgcccaataagtttacatcccagaaacattgagccatcagaaggaactatgtacctgacttgttctttggcctggctaggtaggggatggttatctccctaaggtggggctcaggctccatccttcccctgtgcagataatatctttttcttgctataggctccctcttctgcactgccctgcactctttcctgcaagttgcatctttcctttctctggtcctctgacactttggctcatcacagattccagtgtgtcctgtggacaggctgggggattttgctgctccctattgcttctgtttacacaaatgaatttttcccggtttcccactagggcatgtgagtgggtggcgtgggcctttgttttgttttgttttttgttttttgtctccctggatagaggttgggtttggctgtcttgcagaactggaaaagtagggggtttctagcttggtgcctactggccttgaggcaaggccccctctttccttaactgttaattttttcctgtcccactgcttgggatgaggagttgcagcttcagtgtggaagttcctctttaaggagcctgagtttgggtttaccccaatctggtgatgaagccatgacactttagacctagctcaggcttggaggctggtctggatccaggcctgtgcgcttagagctaccatttcccctccccagcagcccttgtacagacccagatttgctatgcaaaacagtctatcccaggttctgttctggttggctactttgttcagcaacttcacaaaacgtagcacaaacattgattatggagaaggcatcaggactgttgagtaactcctcctttacttctttcctactggctacagtatgggatgccccatgggcacagcccagctgaagaacagaatggagggctctgggaggaggcagctcactggagagcctacattccttacacaagtgcctaaagagagtgatgccaacactccatctgccctgtccatcgccttcatatactgtctacttcgtgttcagtcaccctttggggaggggagctctcttgggacaatgggctctgcatgttctcttcttgggtgcattttggggctgggatcagggcactgttcctggagggtccagtcattcaccagcatttgcaaatatccatagggagctggtggtagccacctactctcagcaacaagtttatgttctctcctttttctctctttgcctcactctctccatttgggttttgagctggggcttgcaatgcattttttagccctttggcattgcacatgctgttcaagaaataaaaaagcaagagaagcaatttgggcgatggcaagaaaataacctcttgctctgaattttttttttttttttaatctttgagacttgaaaaatactttgaccttgatgattattcttgtttgaaagatggtgcatgcagattgagaagtggtgttagcaacaagctttggctttcttggatttggtttaagtggtgcttcttacttatgctctgaggaagtgttgggggaccccagcctcatcctcttggacaggtctcttgcttccttcgttttactgttttgcctctcttttctacttttctctttccttgggatccttttccctttttcaattcactaagcttgtttgctggcctgcctgcctatgtgatgatgaattctctgcatggctacgataatcccactgttagctagcacagtcaggcttagcttcttggctacagacgaccaagaatctgttccccaagcccagtaatgtcctctctgggctggactgccatcaaagttactcagcaggcatgcctacctggcatgaaatcagggggcttctgataacttccacacgtgtccactccttggagtaggtttctctcattgctttttctggatctggttccatttctctctacatgggacctcccttttctgaagacatcctagagttgagctacttggtttccagggttggagggttagggggatggacatagggaaagaagagagtgatgggaagagaatggagagaatttggataaaagatgggaaagagcactgttcgttgatcatttttctagtccagtctgacccattgagggttgaggtgctactgctgaactcaggataagcctggagctgttgttgttcatgggaatttaggcttagaataatgttgaagaagaaagtatctaaaagcgtgaaacctccctaaaaagctcctggttcccatgtactagatagctcctctgtggcctcctgtttggctaaacaacaatgttcttggatagtttggggtgtttttcttttttcttttttttgtccagaattcagtaaatgaggctgacactcaggatgggcagccaaggggacattttgacttcttagctggcccatgggttatctgtctacaaggctggcgaggcagtgttttaaacctggcatcgtgtgtaacaaagaagaatggaaagttccttccctttcagggtggaaagtcctctcaaactagccaaaatgcagttttggaaactacattgggggaagttattttttatatttactgggcctaggccaatctaggatggtagctgggatgccttccttcttaacgtctgatcatggcagggatatgcagggcactctttcctatttagccttctaagcagattggggagaagggattctctggttttctcttccctccccccaccccctccttttattaggacttgccttctccctgggcagggagagaggctaggttggtgctctccccttactctattcctactgatttagaacctccggctgctgtttgggagcctaagaaagggagtggaggtaatgggctcaaaacaaaacagaataaggtggggagggcaaagttccttctttaaaaaggaaaataggaaactctccaaggattgtgcaagtaaagacaatgtgtcgaatgcactgagtcccctggtgtagtagcaataaggaataatgaaatgactttcctgtgcacagtccaacctgattggtgtgtgatgttgcacttagcagccatctggtgggcatgtgtgactactctgggtttcactttagtttctaaactttttatccctctcaagtccagcatggatggggaaatgtccctgaagccccacagctgtgtacttgtttgcatttgtttccctttgagacttgtgtttgtgtcctgctttgagctgtaccttgtccagtccattgtaaaattatcccagcagctgtaatgtacagttccttctaaagcaagcaacagcagcagcacaattctgtgttttataaagacaacagtggcttctatttctaaagtgcggtctctctctctcttttcccccacccccattagcaaagcaaactgttgggattaattatatgtgatagattttaggttagagtaatagattgttataagagcagaaccattacttctagaggaaaatggataaaaaacaccagagtattgaaactgcagattgtatgtaatcatacgtcacaaggcctccatttattcttcattcaacaaaccatgtaaagcactgtgtccagcagtgttgttaggggagatggcaaacataattcaaaaaggaggaaaaccatgtctctctccttaaggagcttaaagtttggtggtggtgggtgggtatgagtggccaaatggttccctggtacaggagagaaatgatgaaggactgaaacaaggctataaggctatacaccagtgaagataggaaagggaagatttttgagagacactcagaaagaattaataggactcaatagatggtgaaagaggaatagacactaatgctcaggtttctgcttgagcaatgagtatatcgggacattcttctaaccaagactaggggagaagggagactagatggaaggtggtgaattttgtgaagacagttagccttgtatagatggagtttggaggttcccatgaggcaacaattttaaggtttccagtaaacacttatattttggtgctcagggaagactataaaactgtagttgtagataatgggattcatactcctatatatggtaggtaaagccataggaataaacaaaatagcttagaaaaagagcgagaaaaacatagtatccagttctggaaacacaatttaaaggatgaagacaggaagctgaacctaagaagacagtcaaatcactagtagataccttgtatattttttacttaatgaggtaggagaaaaaagagaatggaataggatccaagaagggcataatcaacaacatgaactgctgcagtgaggaggaggtattttttttctactcagtttatcatcctccaccccatcttctttgggatcttataactatatggtcattcagtatttcttgaaaatgagcattggaaaaacctaatttaaataaagctaagtctaggacttcgagttgttcatcacaaccaccacttccacctccagcttcctcctgtcctcaggagttacttgtaaaagaataaaataaacaaacctaattttgttcctaa

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