LOCUS       XM_029713151            4498 bp    mRNA    linear   VRT 10-JUL-2025
DEFINITION  PREDICTED: Salmo trutta NRDE-2, necessary for RNA interference,
            domain containing (nrde2), transcript variant X2, mRNA.
ACCESSION   XM_029713151
VERSION     XM_029713151.1
DBLINK      BioProject: PRJNA550988
KEYWORDS    RefSeq.
SOURCE      Salmo trutta (river trout)
  ORGANISM  Salmo trutta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
            Salmoniformes; Salmonidae; Salmoninae; Salmo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_042981.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_901001165.1-RS_2025_07
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 07/09/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4498
                     /organism="Salmo trutta"
                     /mol_type="mRNA"
                     /db_xref="taxon:8032"
                     /chromosome="25"
     gene            1..4498
                     /gene="nrde2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 17 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:115162137"
     CDS             591..4166
                     /gene="nrde2"
                     /codon_start=1
                     /product="protein NRDE2 homolog isoform X2"
                     /protein_id="XP_029569011.1"
                     /db_xref="GeneID:115162137"
                     /translation="

MTSYSCDCLRAEAINMALFPAFAGLSNTKAENAHKELEWLSNQSFRTDDALSLHQRATEKANETQSAETRLVIPEREDKNDVQSNKKKKKEKKKKKKKHKKKSGEPSPASSGSDSDTIYPSDLLKKAESTPPSEEVQFQVEGSFVWLDDLQTPTDRPFCVDRRADRANWEYKSLYRGDIARYKRKGSSSLGLDLRSQAVSWAESGPEKKRVDRRQRPNRYFSPTVRQLLMSDGKPTLPRPPPEGTTTTLPFIPVPSCLEGEAEGGGSAKGQGSWFNPLGVYDSSTSLWLQGKGKAEHGKTEEQPSTPRDNAAVMLAERVEDFNRRLRETPTDTHTWLQFVLFQDEVAGAPGVFGDISENETERRKRSVRATLEKKVAILDRAVENNPSCVELKLERLRLCRELWEPAALLKEWKKLVFLHPNSAPLWRKYLLFMQSHFSTFSVSKVNTVYGKCLSTLAAVQDGSMVSHQVLPGTDEHMLAIFVQQCHFLRQAGHSEKAVCLFQGLLDFTFFKPDTVKDLPTRQQVEFFEPFWDSGEPRVGERGASGWRAWMTQQERGGWLQPSEQDDGDEEDQEELEVKDKTWPKWRIWLDVETSREAIHWLPWRPDKTKGQSVEDCEDPDRQVLFDDIGPSMIRLVRPDLQLCLLLSFLHFLGLPADTSCYSAPSCSLLLDDQALLGDVHHPDSPLTSYDLPVPGVSPVGHMTSLQGARRGAGLCKQGEEFVDNVFQMVLPLFSAQERAVLSLHWIQYEKLKVLRCVRGRNKKRVKSQGKRSKRLAKRLLKEPENRGRLSLWREYAHLEWLLGNLDEAHKVFDTALGLGVAGGLADPALCDLCLLYAQLEVEEAWRRDKGGAGTTVTTAMSSPAVYILTKLAEGSSYAPFLGQLAPVAVLKARKAYEQAVVSSLPGLDEGAAGQGQSKKSRRVKGLVGCYALFQYLTVGVDAADAVYNLARKRLEQHSSMSAQESASSEVMCDIQTLSSVSECEALAVQQVALLRYHTSTNVYPLSHIRLALTSALAHFASSTSLWQLYVQVENRYHSAGRARRFFHSVTKASASVVPRLFAISAEQQRKQLVDSVQRSDCYGDTLSTLPENGLSNRIRSLFENAIATEHGVHCPLLWRMYMNFLVSEGKVEQGRGIFYKALQDVPWAKGLYMDAVQLFPEHVQEFLDLMTEKELRLRVPMEEVDILLED"

     misc_feature    1059..1358
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(1059..1085,1092..1097,1107..1112,1116..1118,
                     1122..1166,1173..1181,1185..1193,1215..1223,1239..1244,
                     1248..1253,1260..1280,1299..1310,1329..1358)
                     /gene="nrde2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1554..2552
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
ORIGIN      

tctgctcattgtacgggagtccaggattggctacgttggatctgcaatgcgtcaagcaatggcgcctaatattacccgagtagtttaggaaaacggtgtggccggacagtctactttgtatcacagagcgttttataatactataattattgctgtcgacaagacgtttctttcagtctgtctagttccacaaaatcatacatcctcatctggcaggggctcgattagagttttttgggaggaatggtggtgatcggcgattggtcaccgcaagcatacacggaactgtttacttttagtcgcggaattgaacatgacaggtgtatcaatgagggaatatataattaaaatattagaaatcctgtgctgattgagtctattttgtgaattaaactactgcattcaaaccaagatttacttttaggcaataatctcgcagtctatggaagtgagtttgtgtgctcatgctcaaggataaataagccaaactaaaccatacaatttgcattcaagagaacaggattttagcagcctaaaattatgcgattcctaaaattctatctctccaacaaaccacaggcgcgttcgagatgacatcatattcatgcgactgtttacgcgcagaggctatcaacatggctctatttccagcttttgcaggattatcaaatacaaaagctgagaatgcacataaagaactagaatggctgagtaatcaaagtttccgcactgatgacgctctctctcttcaccaacgagccactgagaaagccaacgaaacacaatcggcagaaacaagactcgttataccagagagggaggataagaatgacgtccaatccaacaagaagaaaaagaaggagaagaagaagaaaaagaagaagcacaagaagaagagtggagaaccctctccagcaagcagtggctcagattcagatactatctaccccagtgacctcctaaaaaaggctgagagcactcctcccagtgaggaggtgcagtttcaggtggaggggtcttttgtgtggttggatgacctccagacccccaccgatcggcccttctgcgtagacaggagagcagaccgtgccaactgggagtacaaatcactttacagaggagatatcgctaggtacaaaaggaaaggctcttcctctctgggtttggacctgcggtctcaggccgtgagctgggctgagtctggcccagagaagaagagagtggacaggagacagagacccaaccgctacttctcccccaccgtccgccagctgctgatgtctgatggcaaacccacgctgcccagacctccaccagagggcaccaccaccaccttacccttcatccctgtgccctcctgtctggaaggtgaggcagaggggggtggctctgccaaaggccagggctcctggttcaaccccctgggggtgtatgactcctccacctccctgtggctccaggggaaggggaaggcggagcatggcaagacagaggaacaaccttctactcccagggacaatgctgccgtcatgctggctgaacgggtggaggacttcaacaggaggctgagggaaacccccacagacacacacacctggcttcagtttgtcctcttccaggacgaggtagctggggcgcctggggtgtttggtgacatctctgagaacgagaccgagcggcggaagaggtcagtgcgggccacgctggagaagaaggtagccattttggatcgagcagtggagaataatccgagctgcgtggaactgaagctggagcgactgcggctctgtagggagctgtgggagccggcagccctgctgaaggagtggaaaaagctggtgttcctgcaccccaacagcgccccactgtggaggaagtacctgctgttcatgcagagccacttcagtaccttctccgtgtcaaaggtcaacacggtatacgggaagtgtctgagcacgctggcggcggtgcaggatgggagcatggtttctcaccaggtgctaccgggcactgatgaacacatgctggccatcttcgtccagcagtgtcatttcctcaggcaggctggccactcagagaaagctgtgtgtctgttccagggcctactggacttcaccttcttcaagccagacactgtcaaggacctacccaccagacaacaggtggagttctttgagccattctgggacagtggggagccccgtgtcggggagagaggggccagtggatggagagcctggatgacccagcaggagagagggggctggctccaacccagtgaacaagatgatggagatgaagaagatcaggaggaattggaggtgaaggataaaacctggcccaagtggaggatctggttggatgtggagacatcacgcgaggccatccattggctgccgtggaggccggacaaaaccaagggccaatcggtggaggactgtgaggacccggaccgacaggtgctgtttgatgacattgggccgtctatgatccggttggtccgcccagacctccagctatgtcttcttctgtccttcctgcacttcctgggtctacctgctgacacttcctgttacagcgccccctcctgtagcctgctgctggatgatcaggctctactgggggatgttcaccaccctgactcaccactgacctcctatgacctccctgttcctggggtcagccccgtgggtcacatgacctccctgcagggtgccaggaggggggcggggctgtgtaagcagggggaggagtttgtagacaacgtgttccagatggttctgcctctgttctctgctcaggagagagctgtcctctcactacactggatccagtatgagaagctcaaggtgctgaggtgcgtgcgcggcaggaacaagaagcgtgtgaaatcccaggggaagaggagcaagcgcctggccaagcgcctgctgaaagagccagagaaccggggccgcctcagcctgtggagggagtacgcccacctggagtggctgctagggaatttggacgaggcccacaaggtgttcgacacggccctgggactgggcgtggcaggagggctggcagaccctgccctgtgtgatctctgcctgctctacgcccagctggaggtggaggaggcctggcgaagggataagggcggagcagggacgactgttacgaccgccatgtcttcaccagcggtctatatcctcaccaagctagcagagggtagttcgtatgcccccttcttgggacagttggctccagtggccgtgctgaaggccaggaaggcctatgagcaggctgtggtgagctccctgcctgggctggacgagggggccgcggggcaggggcaatccaagaagtccaggcgggtcaaaggtctggtggggtgttacgccctattccagtacctgactgtgggggtcgatgctgctgatgcagtctacaacctggccaggaagaggctggagcaacactccagtatgtcagcccaggagtcagctagcagtgaagttatgtgtgacatacagacactgagctctgtctcagagtgtgaggccctggctgtccagcaggtggcgctgctgcgctaccacaccagcaccaacgtgtacccacttagccatatcagactggcgctgacctcggccctggcccactttgcctccagcacttctctgtggcagttgtatgtgcaggtggagaaccgctaccacagcgccggcagggctcgccgcttcttccacagcgtgaccaaggctagtgccagtgtcgtgccacgcctgttcgccatcagcgcagagcagcaaaggaagcagctagtggactctgttcagaggtctgattgctatggcgacaccctctccaccctgccagagaacggcctgagcaaccgtatccgctcgctgtttgagaatgccatagcaacagagcacggggtccactgtccgttgctgtggaggatgtacatgaacttcctggtgtcagaggggaaggtggagcagggaagagggatcttctacaaggctctacaggatgtcccatgggccaagggtttatacatggacgcggtgcaactcttccctgagcacgtgcaggagttcctggacctgatgacagagaaggagctcagactgagggttcccatggaggaggtggacatactgctggaggactgatgctctaaaacccttcccacagtgcactggggcctggcttcctcagacactccactgtggatacccaaagttgtgcactgaccaatagaacagccaagtgtcctcatgaagaagagcattttacttttcaaacagacgtgtgaataaatgatgttacacttattagtgttaattcaatattttgatggattgcatatccatatttttatatttccagctttttatggattcttaatccatattttgatggatataatatcctatttttatgtcaaagatttgttttgaaacggattaaaaaagagaactgaaataaacgttttgtttcctaa

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