LOCUS       XM_029563128            3333 bp    mRNA    linear   ROD 24-JUN-2019
DEFINITION  PREDICTED: Nannospalax galili protein argonaute-1 (LOC103733310),
            transcript variant X5, mRNA.
ACCESSION   XM_029563128
VERSION     XM_029563128.1
DBLINK      BioProject: PRJNA254049
KEYWORDS    RefSeq.
SOURCE      Nannospalax galili (Upper Galilee mountains blind mole rat)
  ORGANISM  Nannospalax galili
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Spalacidae; Spalacinae; Nannospalax.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_008337140.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Nannospalax galili Annotation
                                           Release 102
            Annotation Version          :: 102
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3333
                     /organism="Nannospalax galili"
                     /mol_type="mRNA"
                     /isolate="Female #2095"
                     /db_xref="taxon:1026970"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="brain"
                     /country="Israel: Animal Facility of the Institute of
                     Evolution, University of Haifa"
     gene            1..3333
                     /gene="LOC103733310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 7 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 2 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:103733310"
     CDS             124..2244
                     /gene="LOC103733310"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X5"
                     /protein_id="XP_029418988.1"
                     /db_xref="GeneID:103733310"
                     /translation="

MPHRVGACARGTSSLPVPARYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    190..342
                     /gene="LOC103733310"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    343..705
                     /gene="LOC103733310"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(499..501,544..546,586..588,598..600,652..654,
                     673..675,679..681)
                     /gene="LOC103733310"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    838..2115
                     /gene="LOC103733310"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1249..1251,1261..1263,1297..1308,1315..1317,
                     1339..1341,1348..1350,1360..1362,1372..1374)
                     /gene="LOC103733310"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1453..1455,1459..1461,1669..1671,2083..2085)
                     /gene="LOC103733310"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

ggcgcatgttgcatgaagccctggtcagtggccagatccctgtgcccttggagtcagtgcaagccctggatgtggccatgaggcacctggcatccatgaggccagggctcctacgtgcccaggatgcctcacagggtgggggcctgtgcccgagggaccagttctctgcctgtccctgccaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctacaaagcacagccagtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcaacccaaaccccttacagattcccagcgtgttcgctttaccaaggagatcaagggcctgaaggtggaagtgacccactgtggacagatgaagaggaaataccgtgtatgtaatgttacccgccgccctgcaagccatcagacgttccccttgcaactggaaagtggacagactgtggaatgcacagtggcacagtatttcaaacagaaatataaccttcagctcaagtatccccacctaccctgcctacaagttggccaagaacaaaaacatacctatctgccactagaggtctgcaacattgtggctgggcagcgctgcattaagaagctaactgacaaccagacttcaaccatgataaaggctacagctaggtcggccccagacagacaggaggagatcagtcgtctgatgaagaatgccagctacaacttagacccttacatccaggaatttggaatcaaagtgaaggatgacatgacggaggtgacggggcgagtgctgccggcgcccatcttgcagtatggcggccggaaccgggccattgctacacccaaccagggtgtctgggacatgcggggaaaacagttctacaatgggattgagatcaaggtctgggccatcgcctgctttgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcacagaccagctacggaagatttccaaggatgcagggatgcccatccaaggtcagccttgtttctgcaaatacgcacagggggcagacagcgtggagcccatgttccggcatctgaagaacacctactcagggctgcagctcattatcgttatcctgccagggaagacgccagtgtatgctgaagtgaaacgtgttggagataccctcttgggaatggcaacacagtgtgtgcaggtgaagaatgtggtcaagacatcacctcagactctgtccaacctctgcctcaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgctgtttttcaacagccagtgatattcctgggagcagatgttacacatcccccagccggggatgggaaaaaaccttctatcacagcagtggtaggcagcatggatgcccaccccagccgatactgtgctactgtgcgggtacagcgaccacggcaggagatcattgaagacttgtcctatatggtgcgtgaattgctcatccagttctataaatctacccgcttcaagcctacccgaatcatcttctaccgagatggggttcctgaaggccagcttccacagatccttcactatgagctgcttgccattcgagatgcctgtatcaaactggaaaaggactatcagcctgggatcacttatattgtggtgcagaaacgccatcacacccgccttttttgtgccgataagaatgagcgaattggaaagagtggtaacatcccagccgggaccactgtggacaccaacatcacccacccatttgagtttgacttctatctgtgcagccatgcaggcatccagggcaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcagatgaactccagatcttgacataccagctgtgccacacttatgtgcgatgcacacgttccgtctctatcccagcacctgcctattatgctcgtttggtggctttccgggcacggtaccacctagtagacaaggagcatgacagtggagaggggagccacatatcgggacagagcaatgggcgggacccccaggccctggccaaagctgtgcaggttcaccaggatactctacgcaccatgtactttgcttgaaggcagaacgctgttacctcactggataaaagaaagctttccaagccccaggagctgtaccgcccaaatccagaggaagcaaggaagagggaggtggggtagggaggagtgcaggaggccttgtttctgtcttacagagggggggaaacagggccggcaagacagaccatcagccagaaatctctgatagcaacctcatgttctccactcctctccccatcttgtcacatctggctctgatcccactggaccaagaggggcagcactagtgcccaccatatacacaggtgtttcatgtgactcacagtgctaaagactcatgcttgacagcttggtaaggtcagctctgcagtcctgcggtcgatcaaaagctggtaggtttgggtttgatattttagatgggaaagtgaggggcttaaaaatgtgggtgggataagggaagaaatttttaggagccttaatctgaaaaggtctagatttgtttaaaaagaaaaatgaaaacagacccagatcaatattttaggatactagatgttttcatgggttcagaatccagtttgtaggaagatttttaatgctatggttttggctgctcctcctcagctgccatctaccctgccacccccttattcctttctctatattttcctaccccaccttacacttcttccctgacagacatccagccccctagtaacacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctactggtgggtaaccagtgccttccctgtaatggtaatgctgcagaactgcaaccttttgtacttttctttgtgggatggggtggggtgggaggggaggttgggagggaagaaatatcccaactccaacaaacctccagccagaatgccagctatttttcatttgaaggaattaacttccatattcattgagcttttaaaaagatcacaacctcaagatggttaaattccattgacatttgcactttcagacatgacaagtctctgagctgctgagatgactggcccttggcctttccactttagcctcctcttttccctaaccccccagcccc

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