LOCUS       XM_016218367            5285 bp    mRNA    linear   MAM 11-APR-2016
DEFINITION  PREDICTED: Miniopterus natalensis argonaute 3, RISC catalytic
            component (AGO3), transcript variant X4, mRNA.
ACCESSION   XM_016218367
VERSION     XM_016218367.1
DBLINK      BioProject: PRJNA317472
KEYWORDS    RefSeq.
SOURCE      Miniopterus natalensis
  ORGANISM  Miniopterus natalensis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Microchiroptera;
            Vespertilionidae; Miniopterinae; Miniopterus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_015504134.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Miniopterus natalensis Annotation
                                           Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5285
                     /organism="Miniopterus natalensis"
                     /mol_type="mRNA"
                     /isolate="MN2012-01"
                     /db_xref="taxon:291302"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="skeletal muscle"
                     /dev_stage="adult"
                     /country="South Africa"
                     /collection_date="Oct-2012"
     gene            1..5285
                     /gene="AGO3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 1 sample with support for all
                     annotated introns"
                     /db_xref="GeneID:107541315"
     CDS             419..2299
                     /gene="AGO3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X4"
                     /protein_id="XP_016073853.1"
                     /db_xref="GeneID:107541315"
                     /translation="

MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQDEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    419..760
                     /gene="AGO3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(554..556,599..601,641..643,653..655,707..709,
                     728..730,734..736)
                     /gene="AGO3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    893..2170
                     /gene="AGO3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1304..1306,1316..1318,1352..1363,1370..1372,
                     1394..1396,1403..1405,1415..1417,1427..1429)
                     /gene="AGO3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1508..1510,1514..1516,1724..1726,2138..2140)
                     /gene="AGO3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

cttccttgagaagcagtatttgacacccttcaccccccaagtctgaaaaacagaagaggaggaaaggcttttcaactcagttttataaggctagtatacctctgatactgacacttgagaaaaaatataattctctcaacggaagaatcatttgacacattttaactttctcatgataaaaatttacagcaaactagcaatagaagaaaacttcctcaacctgatcaaagcatctacaaaaatatacaggaatcatcatagtgaatggtgaaaaaatttaatgcttttgcctgaagctcaagaacaaggcaaggatacttgccctcgctacttctattcagtattttgctggagatccagaccagtgcagtgagtttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgacattcataatattgatgagcagccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacaagaaggcctgccagtcatcaaacctttcctttacagttagaaaatggccaaactgtggagagaacagtagcacagtatttcagagaaaagtatactcttcagctgaagtacccacaccttccctgtctgcaagtggggcaggagcaaaaacatacctatctgccactagaagtctgtaatattgtggcagggcaacgatgtatcaagaagctaacggacaatcagacttccactatgatcaaagcaacagcaagatctgcaccagatagacaagacgaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagttccaatttaaagttcgggatgaaatggcccatgtaaccggacgtgtacttccagcacctatgctccagtatggaggacggaatcggacagtagccacaccaagccatggagtatgggacatgcgagggaaacagttccacacaggagttgaaatcaaaatgtgggctatagcttgttttgccacacagaggcagtgtagagaagaaatactcaagggtttcacggaccagctgcgtaagatttctaaagatgcaggaatgcccatccagggccagccttgcttctgcaaatatgcacagggggcagacagcgtggagcccatgttccggcatctgaagaacacctattctggtcttcagctcatcatcgtcatcctgccagggaagacgccagtgtatgcggaggtgaaacgtgtaggagatacacttttgggtatggctacacagtgtgttcaagtcaagaatgtgataaaaacatcccctcaaactctctcaaacctgtgcctaaagataaatgttaaacttggagggatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagcagatgtcactcatccaccagctggtgatgggaagaagccttctattgctgctgttgtaggtagtatggatgcccacccaagcagatactgtgctacagtaagagttcagagaccccgacaggagatcatccaggacttggcatccatggtccgagaacttctcattcaattttataagtcaactcggttcaaacctacgcgtatcatcttttatcgggatggtgtttcagagggacagtttaggcaggtattatattatgaactgctagcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctacattgtagttcagaagagacatcacactcgattattttgtgctgataggacagaaagggttggaagaagtggcaatatcccagctggaacgaccgtggatacagacattacgcacccatatgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgtccttcacactatcatgttttatgggatgataactgctttactgcagatgaacttcagctgctaacttaccagctctgccacacttatgtgcgctgtacacgttctgtttctatacccgcaccagcgtattatgctcacctggtggcattcagagccagatatcatctcgtagacaaagaacacgacagtgctgaaggaagtcacgtttcaggacagagcaatgggcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaaaaaagtccgagaatgttctctgagaggaagaaccagaagacgaattgacatacgatgtatgtttccagtggagtcagttgagcggggatgcctccagccatacagaaaccaacactgtgggaccagggtctgatttttatgttgatgcaaggaagattgtttacttcatccaggaacacagcaccatatgcaatatgaaaccagccaactgctttttcgtgcggtctcctgtaggaagtatcgccattgttttgttttcactttcttgtagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaaaaaagaaagaaaaggtaaatgatggttttaaaaaacacacctacatgaataatcagtgattgttcacaattatgtgtgcaacattagtgtgtattcgtgtattcttgtaaagtatctgtgtacactttaaatgtatacatgtatacttcatatgcatatatatctggatctacagtgataatagatatatatgttctctgtatatattttatagttcattccattgggaaatgtctttcccttttattatcctcttgccaccactttattcctcgctctacctccctcacctacattttttttccttaatgctaccagtgactttcagatgttcacgtatctggttcatttgagtatgaagcgcggcaaactagactttatttttatttgcacacccactcctgcctcttgtctcatacacaattctgagtcctcaactcttgatattgctttcttaagaagcaaaattattttatgtatgtatatatacgtttttatgagagtctgtgctgccccctcctactccgaacttaacatttgccatttgtgcaatgtgtacataagcagtggcaacctaaactattctcttttttttagtgagtttgttaaagctgctataaatataaaaccttgtctgaagttataactctttctctctataagtgatatatattctaaagccttctgtttctatgggttatacatggaaatcccctaaagcttttataaagagtaaatattttaagtgattgcagctctgtagggttgaggcctctgaaattggatgaagagaaagaagaagttgttgagggtttttaaaaatattttttttgctagtttacttgctgcctctcatacattaatgtgattttcatatatatatttttatatatatgtgtgtatatataaacatatatgtatgtattttgaagtagagcttccttttcttttatatttattagaatagtgctttaataattatagaactgtattggcaacatcttttatagaaatataatcatgtttattttaagaactgacaacttgtttatgctatcttttagtgcaataagcagttttaaaggaaagctgtgtctgtttgacatcggtaccacagatagtggaagaaacaggcacctccataatgttaaaagagcaactaatacagccttaatttcagaaggaaagttttgcaattttcaagtctaaagcatgtctttaaaagtcacaatgaaaatgaaggaaattgatatcctaaatgagtttaaccttgaatattaaaaataaagaactttgatttacaaaatgatcatgactagattaagattttagaagatatttaaattctttgaaaataaatcatatttactaaagaatggttaggtacccattttcatttattaaaatgaatcaggaaaatgtgatcttctaaaaaaaattttgctgatttatcaccagtgtaactttccttttaaaattagggttatgatgacgaagttagggcttggattatttttaaatgagttaaatcactgaaatgtggggaaagttttgcaaaacttttgttttattgatttcactttaagatattaaatagtactataaagctgtcaaaaccaagttcaccagtaacattggattcaggggagctttgcacttttgtaactcatgaaaattgcattttaatttaatttttttttttgcactggttcagagtataaatattacagattgtttccagtgggcattgttgttaacctttcaaaattccatctgttcatgaaaacaaatggattagctctatagtttctctcttacctgtaatccattcttattgccaatttactgtattttgagcctaaaatctgagcccgtgtcctccaacagttacgaaatcttttgtccctccgccagaaaactaagaaagtactgtattttgtatgtttattatattgaagtgtttgaaatgctatttacaacactgtttcaaagctctttacacgaggtaatatttgtataatatatacattttttctcccaaccttccctcctctcctccaaaaaattcctgtaaagcatgtattttttttttatgttgaaactttactaaatatagtagtcaggaacatgggcaagagaagaaaatagtgtattgtatgtggtaaaaacttgattgctctgtgcttgcttagtatgagtaaaacatcttcctttttcagtgggagttatacagaaactttagggcccagggaagaactatagacacccttccctagttcctgttttacctaattttgagttacttagtttcacattcactagagggaagcccataatttaaatctatttagaaagacttttacaaaggaaagaaaaaatgttttaaatataaagctttacctttgaagtgagttcttttttagagtttcttacagtttcaatattactagtttaaggttggttaacttgaaagagtatgtatagtatatttctattttgcttactaacaaattagtatgtcaatcttaactacaagaaatcttgtacttagagttttaagataaaagactaagaggcaaatacattttgaattttgttttaattgttattgcacttctggtatagaattcctggtgtttttcattttttaaa

//