LOCUS       XM_015561416            3561 bp    mRNA    linear   MAM 09-FEB-2016
DEFINITION  PREDICTED: Myotis davidii argonaute 2, RISC catalytic component
            (AGO2), mRNA.
ACCESSION   XM_015561416
VERSION     XM_015561416.1
DBLINK      BioProject: PRJNA232515
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Myotis davidii
  ORGANISM  Myotis davidii
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Microchiroptera;
            Vespertilionidae; Myotis.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_006282874.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Myotis davidii Annotation Release
                                           101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 6.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 3% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3561
                     /organism="Myotis davidii"
                     /mol_type="mRNA"
                     /db_xref="taxon:225400"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="spleen, kidney and small intestine"
                     /country="China: Taiyi Cave, Xianning, Wuhan, Hubei
                     Province"
                     /collection_date="21-Aug-2011"
     gene            1..3561
                     /gene="AGO2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 18 Proteins, and 97% coverage of
                     the annotated genomic feature by RNAseq alignments"
                     /db_xref="GeneID:102762576"
     CDS             16..2742
                     /gene="AGO2"
                     /codon_start=1
                     /product="protein argonaute-2"
                     /protein_id="XP_015416902.1"
                     /db_xref="GeneID:102762576"
                     /translation="

MAQPGPSCFREPPVPFPFLFGSRVTWPLCLAVLAPPAPPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGREKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASNQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYGRRTAGGSGAASRGAGRWWGGPSSASSAWSHAALPRPVRLSECVAKRTSPSALAAQEWVPARTGRCPASASSSLSPQGPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGQSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"

     misc_feature    364..588
                     /gene="AGO2"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    616..768
                     /gene="AGO2"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    769..1131
                     /gene="AGO2"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(925..927,970..972,1012..1014,1024..1026,1078..1080,
                     1099..1101,1105..1107)
                     /gene="AGO2"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1264..2613
                     /gene="AGO2"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1951..1953,1957..1959,2167..2169,2581..2583)
                     /gene="AGO2"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

ccggggagggggaggatggcccagccaggaccatcctgcttcagggagccgcccgtcccgttcccgttcctgttcggttcccgcgtgacgtggcctctttgccttgcagtgctcgcccctccggcgccgccgccgccccccatccaaggatatgccttcaagcccccgcccagacccgacttcgggacctcggggagaacaatcaagttacaggccaacttcttcgagatggacattccgaaaatcgacatctatcactacgagttggacatcaagccagagaaatgcccgcggagagtgaacagggaaatagtggagcacatggtccagcactttaaaactcagatcttcggggatcggaagccagtgttcgacgggaggaagaacctctacacagcgatgccccttccgatcgggcgggagaaggtggagctggaggtcacgctgccgggcgaagggaaagaccgcatcttcaaggtgtccatcaagtgggtgtcctgcgtgagcttgcaggcgttacacgatgcactttcggggcggctgcccagcgtcccctttgagacgatccaggccctcgacgtggtcatgaggcacctgccgtccatgaggtacacgcccgtgggccgctccttcttcacggcctccgagggctgctccaaccccctgggcggtggccgggaagtgtggttcggcttccatcagtctgtccgcccttctctttggaaaatgatgctaaatattgatgtctcggcaacagcgttctataaggcacagccagtcatcgagtttgtttgtgaagttttggattttaaaagtattgaagaacaacagaaacctctgacagattcccaaagggtcaagtttaccaaagaaatcaaaggtctgaaggtggagatcacacactgtgggcagatgaagaggaagtaccgcgtctgcaacgtgacccggcggccggccagcaaccaaacgttcccgctgcagcaggagagcgggcagacggtggagtgcacggtggcccagtacttcaaggaccggcacaagctggtgctgcgctacccccacctcccatgtttacaagtcgggcaggagcagaaacacacctaccttcctctcgaggtctgtaacatcgtggcaggacagagatgtataaagaagttgaccgacaatcagacctcaaccatgatcagagcgacggccaggtcggcgcccgatcggcaagaggagattagcaagctgatgagaagtgcgagtttcaacaccgacccctacgtccgggaatttggaatcatggtcaaagatgagatgactgacgtgactgggcgggtcctgcagccgccctccatcctctacgggggccggaataaagcgattgccacgcctgtgcagggcgtctgggacatgaggaacaagcagtttcacacgggcattgagatcaaggtgtgggccatcgcctgcttcgcaccccagcgccagtgcaccgaggtccacctcaagtccttcacggagcagctcagaaagatctccagggacgcggggatgcccatccagggccagccgtgcttctgcaagtacgcccagggcgctgacagcgtggagcccatgttccggcacctgaagaacacgtacacgggcctgcagctggtggtggtcatcctgccgggcaagacccccgtctacggtaggcggacggctggtgggagcggcgctgcttcccggggagccgggcggtggtggggtgggcccagctctgcgagctcagcctggtctcacgcggccttgccacgtcctgtgaggctctctgagtgcgtcgctaagagaacttcgcccagcgccttggccgcccaggagtgggtgcccgcgcggactgggcggtgcccagcctcggcctcaagctccctctccccccaagggccgcccgtgttccagcagccggtcatcttcctgggggccgatgtcacacacccccccgcgggggacgggaagaagccttccatcgctgccgtcgtgggcagcatggacgcccaccccaaccgctactgcgccaccgtgcgggtgcagcagcaccgccaggagatcatccaggacctggcggccatggtgcgcgagctgctcatccagttctacaagtccacgcgcttcaagcccacgcgcatcatcttctaccgcgacggcgtgtccgaggggcagttccagcaggtcctgcaccacgagctgctggccatccgcgaggcctgcatcaagctggagaaggactaccagccgggcatcacgttcatcgtggtgcagaagcggcaccacacgcggctcttctgcacggacaagaacgagcgggtcgggcagagcggaaacattccagcaggcaccaccgtggacacgaagatcacccacccgaccgagttcgacttctacctgtgcagtcacgctggcatccagggaacaagcaggccctcccactaccacgtgctttgggatgacaatcgtttctcttccgacgagctgcagatcctcacctaccagttgtgtcacacctacgtgcgctgcacgcgctcggtgtccatcccagcgccagcatactacgctcacctggtggccttccgcgccaggtaccacctggtggataaagaacatgacagtgctgaaggaagccatacctccgggcaaagtaacgggcgggaccaccaggcactggccaaggcggtccaggtccaccaggacacgctgcgcaccatgtactttgcttgacatgttgtgtttacgattgtgagcggagtcggattcacacgagaccagcgacactcagaccaacggactccagccccgtggcagccagcactggacaccacacgtcgtggactcagccgaggctcctttcccagaatgccttccgtccggatttcacactcgttctgagctgcagacctgtatgagaccccactgtcgcaggagagatggtttgccaaaatctatccgctgcttattaatagtcccgtatttcctaaaaacatctcctaaaagcagtctatgaactcagggctttaaaacatttttaatttatttggtcattcgatttacttgtttttaacacgtgattctgtatggaattgatgggctcaaactagctgtgagcgttctctgagggtgaaagcaacgcaaacactattgtggttttaaagccttgaccattctgacgttgtcactcacgtgtgtcccaccgacactcgtgtgccctgacgtggctccgcaagctcttagggacccgcggtgggcgccccacccgcgggggaaaggggctgggacgccagagaccacgcccactcaacatttctaggtccagagagattggcagccaagtgccattttaataaaaatttattaaaaaaacaaaaaaaaaaagaaaaaagatggtatgccgacagtctaatggtgagattggtcctctaggactgtgacatttattttccaaagtttctaaagaatacgggtctgtggtgatgatacagtacaatcctttcactgtatgtctttaatgtagagaatatatatatctggttgcagtattaa

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