LOCUS       XM_015043203            3348 bp    mRNA    linear   VRT 12-JUN-2025
DEFINITION  PREDICTED: Poecilia latipinna NRDE-2, necessary for RNA
            interference, domain containing (nrde2), transcript variant X3,
            mRNA.
ACCESSION   XM_015043203
VERSION     XM_015043203.1
DBLINK      BioProject: PRJNA305623
KEYWORDS    RefSeq.
SOURCE      Poecilia latipinna (sailfin molly)
  ORGANISM  Poecilia latipinna
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes;
            Poeciliidae; Poeciliinae; Poecilia.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_015113236.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_001443285.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/12/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3348
                     /organism="Poecilia latipinna"
                     /mol_type="mRNA"
                     /isolate="Pla-1442-1.1"
                     /db_xref="taxon:48699"
                     /chromosome="Unknown"
                     /sex="female"
                     /dev_stage="adult"
     gene            1..3348
                     /gene="nrde2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 2 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:106954008"
     CDS             70..3252
                     /gene="nrde2"
                     /codon_start=1
                     /product="protein NRDE2 homolog isoform X3"
                     /protein_id="XP_014898689.1"
                     /db_xref="GeneID:106954008"
                     /translation="

MCDAIMALFPAFAEVSENKVEDSSTELDWLNNKSFQAGNALSLHSRFLEKSTEQPNKREESVGRDITCSDGESSGKEDGPPKKKKKKSEKKRKKKKKHKKKSGRASGSSGSDSETIYPSDLKREEEGIRHQPASLGTRFTWLDDLQSPTENPFCVDRKPDPANWTYKSLYRGDVARYRRKGSSSLGLDFRRQGVSWEDSETKKKKKVGVNGNAADRYFSVATRKLLRAAPPVPVIPATPESGDVLNSTSFLPLGDAERDNTRHELDSKAQTSVNPLGVYDSSTSLWMQGKGRLLQDDAKPVAETEEKSEYVAGRTEEFNRRLREQPADTQLWIEFIRYQDELSAAAFGGDEEQQGSDLAERRKSSYRAILEKKLSIADRAVETNPTCVALQLERLRICQDLWEPSTLAKEWKKLVFLHPNSAPLWRKYLLFTQSYFSSFSVTKVNSAYGKCLSTLSAVRDGSMVSHPALPGIEEDMLDIFTQQCHFLRQSGHCEKAISLFQAMIDFSYFKPDSVKKLSTKQQVDFFETFWDSGEARVGEVGARGWKAWMTQQERGGWVQPPAEEEEEEEEEEDEEEVKDRSQPRGTVWLEVESSREAAHWLPWRPDKAKGQSEEDCEDPDRQVLFDDIGPSLICLTSPELQLRFLLSFLAFLGFPVDFVLSAAPYQPSMLLENLSLLTQGASLQRPLTSFNPLETGINPVGHMTTLQGTRKWLGLGKQGEKFLTNVFSMLQPFLPPPHRAVLSLSWMLYEKLKVLHCLRSGNKKRLRAQGKSSKRVAKRLLKEPDNRSSLVLWREYAHLEWVLGNLDEARKVFSTATAMGGTRGLGSPALCELCLLWSQLEVENSAKEQGGVADVTTSPAVAVLTRLAEGTSSSSSSQTLTPVSILKARRSYDQALSSSLSSLDQKIQNHQQDGNAAQDEPQEDKLRLRGLVGCYALFQYLTVSIQAASAVYSQARERMEELHRSLTPERQPDHDEATTRPSRTVHSQHVSWLASDCEALAVQQAALLRHNNSVGVCTLATLRQMLTCSLSVWPYSAPLWSVYIQVCSIAPAGHAGFSPL"

     misc_feature    523..834
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(523..549,556..561,571..576,580..582,586..630,
                     637..645,649..657,691..699,709..714,718..723,730..750,
                     775..786,805..834)
                     /gene="nrde2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1018..2028
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
ORIGIN      

cacattactaatctgggcgaaacaacctccacgtgacgtcaaactcctgcgactgtttacatctagcgtatgtgcgacgctatcatggctctttttccagcgtttgctgaagtatcggaaaacaaagttgaagattcgtcgacagaattagactggctgaacaataagagttttcaggctggaaatgctctctcccttcacagtcgttttttagaaaagtccactgaacagccaaacaagagggaggaaagtgttggcagggatattacatgctccgatggggaaagcagtgggaaggaggatgggcctccaaagaagaagaaaaagaagagtgaaaaaaagaggaaaaagaagaaaaagcacaaaaaaaagagtggaagggcttcgggcagtagtggatcggactctgaaaccatctatcccagtgatctcaagagggaagaggaggggattaggcatcagcctgcgtcattaggaactcgttttacatggttggatgacctccagtcgcctacggaaaatccattctgtgtggaccgtaaaccagacccggccaactggacttataagtccctgtacagaggagacgtagctaggtatcggagaaaaggaagttcctctttaggtctggactttcgcaggcagggagtcagctgggaggattctgagacaaagaagaagaagaaagtcggggtcaatgggaatgcagctgacaggtacttttctgtagccactcgaaagctgctgcgggctgcacctcctgttcccgttatccctgcgacgccagaaagtggggatgtactcaactcaacctccttcctccctctgggtgacgctgaacgggacaacacaagacatgagttagatagcaaagcacagacgtcagtaaacccccttggcgtgtatgattcgtccacctccttgtggatgcaggggaagggacgactgcttcaggacgacgcgaagccggtcgcagaaacagaggaaaagtccgagtatgtggctggaaggaccgaagagtttaaccggcgactcagggagcagccagcagatacacagctgtggatagagttcatacgctaccaggacgagctgagtgcagctgcatttgggggtgacgaggagcagcagggcagtgatttggcggagcgccgcaagtcgtcctacagggcgattctggagaagaagctgagcattgcagacagagccgtggaaaccaaccccacctgcgtcgctctgcagctcgagaggctccgaatctgccaggatctctgggaaccctccactttggctaaagaatggaagaaactggtgtttctccatccaaacagcgcccccttgtggaggaaatatctgctttttacgcagagctacttcagcagcttctcagtgacaaaagtcaactctgcatacggaaagtgtctgagcacgctcagcgctgtgagagacggcagcatggtatcccacccagctttgcctggaatagaggaggatatgctggatatcttcacccagcagtgtcatttcttgcggcagtctggtcactgtgagaaggcgatttctttgtttcaggccatgatcgattttagctactttaaacctgacagtgtgaagaagctctccacaaagcagcaggttgatttctttgagacattctgggacagtggagaggcgagagttggggaggtaggagcccgaggatggaaggcctggatgacccaacaagagcgaggaggatgggttcagccccctgcagaggaagaggaggaggaggaggaggaagaggacgaagaggaggtgaaagaccggagccagcccagagggaccgtctggctggaagtggagtcgtcccgtgaagcagctcactggttgccctggagacctgacaaagccaaaggccaatcagaggaggactgtgaggaccctgacagacaggtgctgtttgatgacatcggcccatcccttatttgtctgacttcaccagaactccagctgcggtttcttctcagtttcttggcctttctgggtttcccggtggattttgtgctctctgctgccccctatcagccaagcatgctactggagaacctctcactgctcactcaaggtgcatcgctccagcgtcctctgacttcctttaacccccttgagacggggattaaccctgtaggtcacatgaccactctccaaggaaccaggaagtggttggggcttggaaagcagggtgagaagtttctcaccaacgtgttcagcatgctgcagcctttcctccctcctccccatcgagccgttctgtctctcagctggatgctgtacgagaagctgaaggttttgcactgtctgcgcagcggcaacaaaaagcggcttcgcgctcagggaaagagcagcaagcgggtcgccaagagactcctcaaagaacccgacaatcgctcgtccctggtgctgtggagggagtacgcacacctggagtgggtgctgggcaacctggacgaggctcggaaggtgttctccacggcgacggcgatgggaggaaccaggggccttggcagtcctgctctgtgtgagctgtgcctcctgtggtcccagctggaggtagagaactcggcaaaggagcagggaggagtcgctgacgtaacgacgtcgccagctgttgcggtgctgaccagactggcagaaggaacatcttcgtcttcatcctcccagaccttgaccccagtttcaatcctgaaggccaggagatcgtatgatcaggctctgagctccagcctgtcgtctctggaccagaagatccagaatcatcagcaggacggaaacgcagcccaagatgagccacaggaagataagctgaggctaagaggcctggtcggctgctacgctctgtttcagtacctaacagtgagcatccaagctgctagtgctgtctacagccaggccagggagaggatggaggagctgcaccgctcgttaacacccgaaaggcagcctgaccacgatgaggcaaccacccgcccgagtcgtaccgtgcacagccagcatgtcagctggttggcttcagactgtgaggctttagcagtgcaacaggcggctctgctcagacacaacaatagtgtcggtgtgtgtactttggcaacactgaggcagatgcttacctgttccctctcagtttggccgtacagcgcccccctgtggagtgtttacattcaggtctgctccatagcgccggccgggcacgccggtttttcaccactgtaaccagagacaacagcagcagcgtggtaccccgtctgtttgctattgttgctgaacagcataggaagcagctggtggatgcagctcagaggtgaggct

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