LOCUS       XM_001390757            1086 bp    mRNA    linear   PLN 21-FEB-2025
DEFINITION  Aspergillus niger uncharacterized protein (An05g02260), partial
            mRNA.
ACCESSION   XM_001390757
VERSION     XM_001390757.1
DBLINK      BioProject: PRJNA19263
            BioSample: SAMEA3283178
KEYWORDS    RefSeq.
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
REFERENCE   1  (bases 1 to 1086)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2025) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NT_166521).
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..1086
                     /organism="Aspergillus niger"
                     /mol_type="mRNA"
                     /db_xref="taxon:5061"
                     /chromosome="VII"
                     /map="unlocalized"
                     /clone="An05"
     gene            <1..>1086
                     /locus_tag="An05g02260"
                     /db_xref="GeneID:4980963"
     CDS             1..1086
                     /locus_tag="An05g02260"
                     /EC_number="1.1.1.9"
                     /inference="profile:COGS:COG1063"
                     /inference="profile:PFAM:PF00107"
                     /inference="similar to AA sequence:UniProtKB:AF072541.1"
                     /note="Catalytic activity: xylitol + NAD(+) <=> D-xylulose
                     + NADH.;
                     Cofactor: zinc 2+;
                     Similarity: similarities to L-Iditol 2-dehydrogenases (EC
                     1. 1. 1. 14).;
                     Title: strong similarity to xylitol dehydrogenase xdh -
                     Galactocandida mastotermitis;
                     See PMID 10661867"
                     /codon_start=1
                     /product="uncharacterized protein"
                     /protein_id="XP_001390794.1"
                     /db_xref="GeneID:4980963"
                     /db_xref="GOA:A2QL21"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR002328"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:A2QL21"
                     /translation="

MENPSFVLRNIKDVVIEDRPKPILKDPHDVMVHVAQTGICGSDVHYWQRGRIGDFVLTGPMVLGHESAGVVVEVGDKVRHLKPGDRVAMEPGVPCRRCDYCRSGSYNLCGDTIFAATPPWDGTLAKYYVNAADFCYKIPDHMTLEEAAMVEPVSVAVAIAKTANLQAHQTVLVLGCGPIGVLCQAVAKAAGARTIIGVDVILSRLEVAKSYGIDHTFMPSRAEPGTDPMVHAERVAMXLKEELGLGEGADVVLECSGAEPCVQMGIYAARRGATFVQAGMGKENILFPITAVCTRGLTIKGSIRYLTGCYPAAIDLIAKGKIDVKRLITNRFPFEKAEEAFELVKAGRADVFKVMIAGVQE"

     misc_feature    13..1074
                     /locus_tag="An05g02260"
                     /note="Sorbitol dehydrogenase; Region: sorbitol_DH;
                     cd05285"
                     /db_xref="CDD:176188"
     misc_feature    order(118..120,124..126,136..138,154..156,163..165,
                     193..195,340..342,349..351,451..453,838..840,907..912)
                     /locus_tag="An05g02260"
                     /note="inhibitor binding site [active]"
                     /db_xref="CDD:176188"
     misc_feature    order(118..120,124..126,193..198,451..453)
                     /locus_tag="An05g02260"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176188"
     misc_feature    order(283..285,292..294,301..303,325..327)
                     /locus_tag="An05g02260"
                     /note="structural Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176188"
     misc_feature    order(463..465,529..537,592..600,610..612,655..657,
                     763..768,772..774,832..840,904..912)
                     /locus_tag="An05g02260"
                     /note="NADP binding site [chemical binding]; other site"
                     /db_xref="CDD:176188"
     misc_feature    order(469..471,502..504,508..510,556..558,565..573,
                     577..579,604..606,652..654,721..723,934..936,943..948,
                     955..957)
                     /locus_tag="An05g02260"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176188"
ORIGIN      

atggagaacccctcatttgtcctgcgcaacatcaaagatgtagtcattgaagaccggcccaaacccatcctcaaagacccccatgatgtgatggtccatgtagcacaaacaggtatttgtggaagtgatgttcactactggcaacgcggtcgcatcggcgacttcgtcctcaccgggcccatggtcctcggccatgaatctgccggcgtagttgtcgaagtcggcgacaaagtccgacacctcaaacccggcgatcgcgtcgccatggaaccgggcgtaccctgtcgtcgctgcgactactgccgcagcggatcatacaacctctgtggcgatacgatcttcgctgcgaccccgccctgggacggcaccctcgccaaatactacgtcaacgccgccgacttctgctacaagataccggaccacatgacgctcgaggaagcagccatggtggagcccgtgtctgtggccgtggccatcgccaagacagccaacctgcaagcacaccagactgtgctggttctgggatgcggtccgatcggcgtactatgccaggccgtggctaaggctgccggagccaggaccatcatcggagtggatgtgattctgtcccgactggaggtagccaagtcgtacggcatcgatcacacattcatgccctcgcgggccgagcccggcactgacccgatggtgcatgcggagcgggtagcgatgcanttgaaggaggagctgggtctgggagaaggcgcagacgtggtgttggagtgctctggtgctgagccgtgtgtgcagatgggtatctacgcagcccgccggggagccacattcgtgcaggctggcatgggcaaggagaacattctgttccccattacggcggtgtgcacgcgtgggttgaccatcaagggatccattcggtatctgaccgggtgctatccggcggctatcgacttgattgccaagggcaagattgatgtgaagcggttgatcacgaataggttcccgttcgagaaggccgaggaggcattcgagttggtcaaggctggacgggcggatgtgttcaaagttatgattgcgggagtgcaggagtaa

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